Do Not Be Fooled by Fancy Mutations: Inflammatory Fibroid Polyps Can Harbor Mutations Similar to Those Found in GIST by Bodil Bjerkehagen, Kristin Aaberg, Sonja E. Steigen

“…Surgeons that remove a typical polyp from the stomach or small intestine should be reluctant to accept a diagnosis of GIST just because there is a mutation in platelet-derived growth factor receptor alfa (PDGFRA). Background. A subtype of gastric and intestinal polyps is denoted as inflammatory fibroid polyp (IFP). …”
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Clinical Efficacy and Safety of Pulsed Dye Laser Combined with Pingyangmycin on Hyperplastic Scar after Acne by Rong Guo, Wenxia Xuan, Xiao He, Kai Xu

“…And compared with the control group, the growth factor of the research group was lower, while the treatment comfort and satisfaction, psychological state, and prognosis quality of life were higher. …”
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A Review: Inflammatory Process in Alzheimer's Disease, Role of Cytokines by Jose Miguel Rubio-Perez, Juana Maria Morillas-Ruiz

“…By contrast, other cytokines such as IL-1 receptor antagonist (IL-1ra), IL-4, IL-10, and transforming growth factor (TGF)-β can suppress both proinflammatory cytokine production and their action, subsequently protecting the brain. …”
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First Description of the Clinical Activity of Avapritinib in Sporadic Mesenteric Desmoid Tumor by Rebecca Ganzon, Wei Chen, Gabriel Tinoco

“…Avapritinib is a tyrosine kinase inhibitor (TKI) approved in 2020 for adults with unresectable or metastatic gastrointestinal (GI) stromal tumors (GISTs) harboring a platelet-derived growth factor receptor alpha (PDGFRA) Exon 18 mutation, including D842V mutations. …”
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Clinical and genetic analysis of methylmalonic aciduria in 60 patients from Southern China: a single center retrospective study by Hiba Abid, Areeba Abid, Sarah Sohail, Sara Jawaid

“…We highlight the variability in serum MMA levels due to dietary intake, renal function, and external factors, advocating for the integration of supplementary diagnostic tools, such as the 1–13 C-propionate oxidation breath test, alongside biomarkers like fibroblast growth factor 21, growth differentiation factor 15, and lipocalin-2, to improve diagnostic accuracy. …”
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Facial Papulopustular Eruption during the COVID-19 Pandemic in Patients Treated with EGFR Inhibitors by Eleonora De Luca, Pietro Sollena, Lucia Di Nardo, Ettore D’Argento, Emanuele Vita, Giampaolo Tortora, Ketty Peris

“…Papulopustular rash (PPR) is the most frequent cutaneous adverse event during treatment with epidermal growth factor receptor inhibitors (EGFRis). Although often mild in severity, it can impair patients’ quality of life and may also be a reason for discontinuing or changing the dose of the antineoplastic treatment. …”
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Targeting HER2 in Nuclear Medicine for Imaging and Therapy by Adriana V. F. Massicano PhD, Bernadette V. Marquez-Nostra PhD, Suzanne E. Lapi PhD

“…Since its discovery, the human epidermal growth factor 2 (HER2) has been extensively studied. …”
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In-Trastuzumab Scintigraphy in HER2-Positive Metastatic Breast Cancer Patients Remains Feasible during Trastuzumab Treatment by Sietske B.M. Gaykema, Johan R. de Jong, Patrick J. Perik, Adrienne H. Brouwers, Carolien P. Schröder, Thijs H. Oude Munnink, Alphons H.H. Bongaerts, Elisabeth G.E. de Vries, Marjolijn N. Lub-de Hooge

“…Human epidermal growth factor receptor (HER)2 imaging with radiolabeled trastuzumab might support HER2-targeted therapy. …”
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PPAR-γ Agonists and Their Effects on IGF-I Receptor Signaling: Implications for Cancer by A. Belfiore, M. Genua, R. Malaguarnera

“…It is now well established that the development and progression of a variety of human malignancies are associated with dysregulated activity of the insulin-like growth factor (IGF) system. In this regard, promising drugs have been developed to target the IGF-I receptor or its ligands. …”
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Lung Cancer Prediction Using Neural Network Ensemble with Histogram of Oriented Gradient Genomic Features by Emmanuel Adetiba, Oludayo O. Olugbara

“…These machine learning classifiers were trained to predict lung cancer using samples of patient nucleotides with mutations in the epidermal growth factor receptor, Kirsten rat sarcoma viral oncogene, and tumor suppressor p53 genomes collected as biomarkers from the IGDB.NSCLC corpus. …”
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Neural Compensations After Lesion of the Cerebral Cortex by Bryan Kolb, Russell Brown, Alane Witt-Lajeunesse, Robbin Gibb

“…For example, factors such as gonadal hormones, nerve growth factor, or psychomotor stimulants may act to either enhance or retard recovery, depending upon the timing of administration. …”
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Spinal NGF Restores Opioid Sensitivity in Neuropathic Rats: Possible Role of NGF as a Regulator of CCK-Induced Anti-Opioid Effects by Catherine M Cahill, Terence J Coderre

“…The breadth of peripheral effects produced by nerve growth factor (NGF) in nociceptive processing has been well documented. …”
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Thanatophoric Dysplasia: A Report of 2 Cases with Antenatal Misdiagnosis by Lamidi Audu, Amina Gambo, Tokan Silas Baduku, Bilkisu Farouk, Anisa Yahaya, Kefas Jacob

“…Thanatophoric dysplasia (TD) is a rare but uniformly lethal inherited disorder of the skeletal system resulting from defects in the fibroblast growth factor receptor-3 gene on the short arm of chromosome ##4. …”
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Suppression of Human Tenon Fibroblast Cell Proliferation by Lentivirus-Mediated VEGF Small Hairpin RNA by Zhongqiu Li, Wen Hua, Xuedong Li, Wei Wang

“…The functions of vascular endothelial growth factor (VEGF) in scar formation after trabeculectomy were investigated in a human Tenon fibroblast cell line from glaucoma patients using lentivirus-mediated VEGF shRNA. …”
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Selective inhibition of TGF-β-induced epithelial-mesenchymal transition overcomes chemotherapy resistance in high-risk lung squamous cell carcinoma by Liangdong Sun, Jue Wang, Huansha Yu, Xinsheng Zhu, Jing Zhang, Junjie Hu, Yilv Yan, Xun Zhang, Yuming Zhu, Gening Jiang, Ming Ding, Peng Zhang, Lele Zhang

“…Furthermore, the combination of chemotherapy with transforming growth factor-β inhibition augments antitumour responses in LUSC tumours. …”
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Expansion of CD16-Negative Natural Killer Cells in the Peripheral Blood of Patients with Metastatic Melanoma by Shernan G. Holtan, Douglas J. Creedon, Michael A. Thompson, Wendy K. Nevala, Svetomir N. Markovic

“…Expansion of CD16− NK cells was associated with elevated plasma transforming growth factor-beta (TGF-β levels (median 20 ng/ml, Spearman's ρ=0.81,P=.015)). …”
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Diabetic Macular Edema Pathophysiology: Vasogenic versus Inflammatory by Pedro Romero-Aroca, Marc Baget-Bernaldiz, Alicia Pareja-Rios, Maribel Lopez-Galvez, Raul Navarro-Gil, Raquel Verges

“…Although the vascular endothelial growth factor (VEGF) is known to play a role in the development of DME, the pathological processes leading to the onset of this disease are highly complex and the exact sequence in which they occur is still not completely understood. …”
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Spatial Transcriptome and Single Nucleus Transcriptome Sequencing Reveals Tetrahydroxy Stilbene Glucoside Promotes Ovarian Organoids Development Through the Vegfa‐Ephb2 Pair by Chunlan Mu, Xiaoyong Li, Jiamei Yang, Geng G. Tian, Hepeng Bai, Wenhui Lin, Linhui Wang, Ji Wu

“…This analysis indicates that TSG promotes ovarian organoid development through the vascular endothelial growth factor A‐Eph receptor B2 ligand‐receptor pair between granulosa cells and oocytes. …”
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Neuroprotection as a Therapeutic Target for Diabetic Retinopathy by Cristina Hernández, Massimo Dal Monte, Rafael Simó, Giovanni Casini

“…Upregulation of vascular endothelial growth factor (VEGF), the main target of current therapies, is likely to be one of the first responses to retinal hyperglycemic stress and VEGF may represent an important survival factor in early phases of DR. …”
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Galectin-1 as an Emerging Mediator of Cardiovascular Inflammation: Mechanisms and Therapeutic Opportunities by Ignacio M. Seropian, Germán E. González, Sebastián M. Maller, Daniel H. Berrocal, Antonio Abbate, Gabriel A. Rabinovich

“…In addition, this lectin promotes angiogenesis by co-opting the vascular endothelial growth factor receptor (VEGFR) 2 signaling pathway. Since a coordinated network of immunomodulatory and proangiogenic mediators controls cardiac homeostasis, this lectin has been proposed to play a key hierarchical role in cardiac pathophysiology via glycan-dependent regulation of inflammatory responses. …”
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