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681
Surface topography modulates initial platelet adhesion to titanium substrata
Published 2024-07-01“…In addition, the secretion of critical molecules stored in platelet granules (platelet factor 4, PF4; soluble P-selectin, sCD62P; transforming growth factor-beta1, TGF-β1; platelet-derived growth factor-AB, PDGF-AB) was measured by enzyme-linked immunosorbent assay (ELISA) analysis of the supernatants. …”
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682
Anti-VEGF therapy for proliferative diabetic retinopathy: translating research evidence into clinical practice
Published 2020-06-01“…</i> </p> <p> <i><b>Keywords</b>: proliferative diabetic retinopathy, diabetic macular edema, vascular endothelial growth factor, anti-VEGF.</i> </p> <p> <i><b>For citation: </b>Abdulaeva E.A., Minkhuzina E.L., Kuskov A.N. …”
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683
Bioprinted hydrogels in bone regeneration: a bibliometric analysis
Published 2025-02-01“…Future research directions may focus on gelatin, additive manufacturing, and growth factors. Additionally, international collaboration is essential to enhance the effectiveness of bioprinted hydrogels in bone regeneration applications.…”
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684
Immunoregulative coating for scarless healing in anterior cruciate ligament reconstruction
Published 2025-03-01“…Moreover, it avoids the overuse of exogenous growth factors and potential complications, offering a more convenient and feasible therapeutic strategy.…”
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685
Graphene-Based Materials for Bone Regeneration in Dentistry: A Systematic Review of In Vitro Applications and Material Comparisons
Published 2025-01-01“…Additionally, its ability to act as an effective carrier for growth factors and drugs allows controlled release, facilitating the engineering of specific tissues for bone regeneration. …”
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686
Combination Blockade of the IL6R/STAT-3 Axis with TIGIT and Its Impact on the Functional Activity of NK Cells against Prostate Cancer Cells
Published 2022-01-01“…We analyzed the secretion of cytokines, chemokines, and growth factors in 22Rv1, LNCaP, and DU145 cells. In these cells, we also evaluated the expression of NK ligands, IL6R, STAT-3, and phosporylated STAT-3. …”
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687
Syndecan-1: A Review on Its Role in Heart Failure and Chronic Liver Disease Patients’ Assessment
Published 2019-01-01“…Under various fibrogenetic conditions, shedding of syndecan’s extracellular domain took place, becoming a soluble form that binds different growth factors and inhibits further fibrosis. This complex molecule is also involved in the lipid metabolism, by altering the clearance of cholesterol particles, and in chronic hepatitis, by enhancing the viral invasion of hepatocytes. …”
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688
The effect of conditioned media on the cellular proliferation of pancreatic cancer cells, pancreatic stellate cells, and myeloid-derived suppressor cells
Published 2025-01-01“…Its highly immunosuppressive tumour microenvironment is driven by secreted proteins, such as cytokines and growth factors, which promote the differentiation of immunosuppressive cells and influence cellular proliferation and migration. …”
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689
Comparative Analysis of Tenogenic Gene Expression in Tenocyte-Derived Induced Pluripotent Stem Cells and Bone Marrow-Derived Mesenchymal Stem Cells in Response to Biochemical and B...
Published 2021-01-01“…In this study, we extensively investigated the expression of tenogenic genes in equine bone marrow mesenchymal stem cells (BMSCs) and tenocyte-derived induced pluripotent stem cells (teno-iPSCs) stimulated by growth factors (TGF-β3 and BMP12) combined with ectopic expression of tenogenic transcription factor MKX or cyclic uniaxial mechanical stretch. …”
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690
Markers of vascular autoregulation in primary open-angle glaucoma
Published 2019-11-01“…</i> </p> <p> <i>Associations of genetic polymorphisms of growth factors contributing to the development of primary open-angle glaucoma (POAG) were studied. …”
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691
ZEB1 as a marker of metastasis in thyroid carcinomas: review of literature and own data
Published 2024-11-01“…Downregulation of E-cadherin expression is induced by transforming growth factor β, epidermal growth factor, fibroblast growth factor, and interleukin-6. …”
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692
Intraoperative Local Administration of Platelet-Rich Plasma (PRP) during Neurolysis Surgery for the Treatment of Digital Nerve Crush Injury
Published 2018-01-01“…In addition to conventional therapies such as neurolysis, direct repair, and auto/allografts, new treatments administering growth factors and cells for promoting nerve regeneration exist. …”
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693
Clinical Efficacy of Platelet-Rich Plasma in the Treatment of Neurotrophic Corneal Ulcer
Published 2018-01-01“…Platelet-rich plasma (PRP) is an autologous blood product without preservatives and rich in proteins and growth factors which make it possible for cells to differentiate, proliferate, and migrate, thus stimulating healing and regeneration of tissues. …”
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694
Human Motor Neuron Progenitor Transplantation Leads to Endogenous Neuronal Sparing in 3 Models of Motor Neuron Loss
Published 2011-01-01“…In addition, we have also found that hMNPs secrete physiologically active growth factors in vivo, including NGF and NT-3, which significantly enhanced the number of spared endogenous neurons in all three animal models. …”
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695
Problems of healing chronic wounds
Published 2023-09-01“…In recent years, various methods of stimulating reparative processes have been used in clinical practice to treat wounds: local administration of recombinant growth factors, use of platelet-rich plasma, biotechnological wound dressings, and artificial skin substitutes. …”
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696
Untargeted Metabolomics Reveals Key Differences Between Yak, Buffalo, and Cow Colostrum Based on UHPLC-ESI-MS/MS
Published 2025-01-01“…Background: Colostrum, abundant in immunoglobulins and growth factors, plays a vital role in supporting immunity. …”
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697
Polysaccharide-based biomaterials for regenerative therapy in intervertebral disc degeneration
Published 2025-02-01“…Furthermore, polysaccharide-based hydrogels have demonstrated the potential to deliver bioactive molecules, including growth factors, cytokines and anti-inflammatory drugs, directly to the degenerated disc environment, thereby enhancing therapeutic outcomes. …”
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698
Two new strains of Streptomyces with metabolic potential for biological control of pear black spot disease
Published 2024-12-01“…Both strains contained genes related to amino acid transport and metabolism, along with several CAZY genes and 19 plant growth factors. The resistance genes of strain TRM 76172 were classified as macrolides, and genomic prediction revealed the biosynthetic pathway of the active compound Candidin. …”
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699
Human Umbilical Cord Mesenchymal Stem Cells Encapsulated with Pluronic F-127 Enhance the Regeneration and Angiogenesis of Thin Endometrium in Rat via Local IL-1β Stimulation
Published 2022-01-01“…Conditional medium derived from IL-1β-primed hUC-MSCs increased the concentration of angiogenesis factors (basic fibroblast growth factor (bFGF), vascular endothelial growth factors (VEGF), and hepatocyte growth factor (HGF)). …”
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700
Copper Does Not Induce Tenogenic Differentiation but Promotes Migration and Increases Lysyl Oxidase Activity in Adipose-Derived Mesenchymal Stromal Cells
Published 2020-01-01“…Copper sulfate supplementation can have a beneficial effect on tendon regeneration not by inducing tenogenic differentiation, but by improving the recruitment of MSCs to the site of injury, where they can secrete growth factors, cytokines and chemokines, and prevent the effects of oxidative stress at the site of inflammation, as well as improve the stabilization of collagen fibers, thereby accelerating the process of tendon healing.…”
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