Vitreous Mediators in Retinal Hypoxic Diseases by Roberto dell'Omo, Francesco Semeraro, Giulio Bamonte, Francesco Cifariello, Mario R. Romano, Ciro Costagliola

“…Under hypoxic conditions, a variety of soluble factors are secreted into the vitreous cavity including growth factors, cytokines, and chemokines. Cytokines, which usually serve as signals between neighboring cells, are involved in essentially every important biological process, including cell proliferation, inflammation, immunity, migration, fibrosis, tissue repair, and angiogenesis. …”
Get full text

3D Bioprinting Strategies for Melatonin‐Loaded Polymers in Bone Tissue Engineering by Damla Aykora, Ayhan Oral, Cemre Aydeğer, Metehan Uzun

“…Polymer‐based biomaterials are mostly used for the controlled release of various drugs, therapeutic agents, mesenchymal stem cells, ions, and growth factors. Polymers are now among the most preferable materials for 3D bioprinting. …”
Get full text

Interleukin-1-Beta and Dyslipidemic Syndrome as Major Risk Factors for Thrombotic Complications in Type 2 Diabetes Mellitus by Oana Bădulescu, Codruţa Bădescu, Manuela Ciocoiu, Magda Bădescu

“…The results achieved in our study have revealed the highest thrombotic risk among the groups of diabetic patients, which is in direct correlation with the high values of interleukin-1-beta and the modifications of lipid parameters, acknowledging the data in the literature, according to which hyperglycemia alters endothelial functions directly and indirectly by synthesis of growth factors and cytokines and generates metabolic disorders which would explain the high risk for thrombotic events.…”
Get full text

In Vitro Model for Studying Malignancy Associated Changes by Xiao Rong Sun, Yonghong Zheng, Calum MacAulay, Stephen Lam, Alexei Doudkine, Branko Palcic

“…Our results demonstrate that MAC appear to be specific to changes induced by malignancy, and that these changes differ from those induced by growth factors in the serum. This study provides evidence in support to the hypothesis that MAC are induced by a soluble factor(s) released by malignant cells. …”
Get full text

Angiogenesis in Spontaneous Tumors and Implications for Comparative Tumor Biology by C. Benazzi, A. Al-Dissi, C. H. Chau, W. D. Figg, G. Sarli, J. T. de Oliveira, F. Gärtner

“…Several molecules such as cell surface receptors, growth factors, and enzymes are involved in this process. …”
Get full text

To Compare the Efficacy of Platelet-Rich Plasma with Low-Level Laser Therapy and Low-Level Laser Therapy Alone in the Treatment of Chronic Plantar Fasciitis by Sushil Kumar Saini, Atul Kumar Saroj, Ashutosh Verma

“…Platelet rich plasma (PRP) can be injected to various tissues where it releases high amounts of platelet derived growth factors that increases growth and healing process. …”
Get full text

How breastfeeding affects immunity? by Dawid Piecuch, Weronika Sobota, Katarzyna Zemsta, Przemysław Piskorz, Michał Zwoliński, Edyta Hańczyk, Aleksandra Sędek

“…Breastfeeding offers unique benefits, including providing maternal antibodies, immunoglobulins and growth factors that lower the risk of many diseases. In the work presented here, we focus mainly on the components of maternal milk and the benefits of providing them. …”
Get full text

Mesenchymal Stem Cell-Based Immunomodulation: Properties and Clinical Application by Mengyuan Wang, Quan Yuan, Liang Xie

“…Numerous bioactive molecules secreted by MSCs, particularly cytokines, growth factors, and chemokines, exert autocrine/paracrine effects that modulate the physiological processes of MSCs. …”
Get full text

Liver Fibrosis and Altered Matrix Synthesis by Katrin Neubauer, Bernhard Saile, Giuliano Ramadori

“…At the cellular level, origin of liver fibrogenesis is initiated by the damage of hepatocytes, resulting in the recruitment of inflammatory cells and platelets, and activation of Kupffer cells, with subsequent release of cytokines and growth factors. The hepatic stellate cells seem to be the primary target cells for these inflammatory stimuli, because during fibrogenesis, they undergo an activation process to a myofibroblast-like cell, which represents the major matrix-producing cell. …”
Get full text

Successful pregnancy of a Maine Coon queen despite feline mammary fibroadenomatous hyperplasia recurrence after treatment with aglepristone by P Socha, P Mossakowski

“…One of the disorders of the mammary gland in the queen is feline mammary fibroadenomatous hyperplasia (FMFH), caused by an increasing concentration of progesterone (P4) and some other local growth factors. It occurs mostly during puberty after the heat characterised by spontaneous or provoked ovulation, as a result of exogenous progesterone intake and sometimes during pregnancy. …”
Get full text

Interactions with iridophores and the tissue environment required for patterning melanophores and xanthophores during zebrafish adult pigment stripe formation. by Larissa B Patterson, David M Parichy

“…Here we show that bnc2 promotes melanophore and xanthophore development by regulating expression of the growth factors Kit ligand a (Kitlga) and Colony stimulating factor-1 (Csf1), respectively. …”
Get full text

Postextractive Alveolar Ridge Preservation Using L-PRF: Clinical and Histological Evaluation by Giorgio Serafini, Marco Lollobrigida, Lorenzo Fortunato, Giulia Mazzucchi, Luca Lamazza, Dario Di Nardo, Iole Vozza, Mara Riminucci, Alberto De Biase

“…Leukocyte- and platelet-rich fibrin (L-PRF) is an autologous platelet concentrate rich in growth factors and plasma proteins, obtained by centrifugation of patient whole blood, and widely used in oral surgery. …”
Get full text

A systematic review assessing the osseoincorporation potential of trabecular dental implants: A current evidence and future directions by Karuna S. Patwardhan, Nisha Puranik, Hema Kanathila, Santosh Yamanappa Nelogi, Vasanti P Jirge

“…Histologically, 2 studies showed upregulation of bone morphogenic proteins, collagens, and growth factors with respect to trabecular dental implants. …”
Get full text

Allergic Contact Dermatitis Is Associated with Significant Oxidative Stress by S. Kaur, K. Zilmer, V. Leping, M. Zilmer

“…In 40 patients, interleukin- (IL-) 6, monocyte chemoattractant protein (MCP-1), and IL-10 levels were measured in sera with the Evidence Investigator Cytokine & Growth factors High-Sensitivity Array, total peroxide concentration (TPX) and total antioxidant capacity (TAC) by means of spectrophotometry, and the plasma concentrations of adiponectin and leptin by the quantitative sandwich enzyme immunoassay technique. …”
Get full text

The Effect of a Synthetic Heparan Sulfate on the Healing of Colonic Anastomoses by Malene Nerstrøm, Peter-Martin Krarup, Lars Nannestad Jorgensen, Magnus S. Ågren

“…The mimetic compound OTR4120 may replace endogenous-degraded heparan sulfates that normally maintain the bioactivity of growth factors that are important for tissue repair. Herein, we investigated the effect of OTR4120 on the healing of normal colonic anastomoses. …”
Get full text

Mesenchymal Stem Cell–Sourced Exosomes as Potentially Novel Remedies for Severe Dry Eye Disease by Carl Randall Harrell, Valentin Djonov, Ana Volarevic, Aleksandar Arsenijevic, Vladislav Volarevic

“…MSC-Exos contain a variety of bioactive proteins (growth factors, immunoregulatory molecules, cytokines, and chemokines) lipids, and microRNAs (miRNAs) which affect viability, proliferation, phenotype, and function of eye-infiltrated immune cells. …”
Get full text

Successful Control of Acute Myelofibrosis with Lenalidomide by G. Vassilopoulos, M. Palassopoulou, K. Zisaki, M. Befani, E. Bouronikou, N. Giannakoulas, E. Stathopoulou, P. Matsouka

“…The patient was treated for four months with anabolic steroids (Danazol), growth factors and received regular blood transfusions. …”
Get full text

Clinical Characteristics of Patients with Newly Diagnosed Diabetic Macular Edema in Turkey: A Real-Life Registry Study—TURK-DEM by Bora Eldem, Sengul Ozdek, Ali Osman Saatci, Emin Ozmert, Esat Ulay, Gulsah Nomak

“…Laser photocoagulation (32.1%) and antivascular endothelial growth factors (anti-VEGF; 31.8%) were the most commonly planned treatments. …”
Get full text

Perbandingan Perubahan Luas Luka dan Angiogenesis pada Luka Bakar Derajat IIB Tikus Sprague Dawley yang Diberikan Advanced Platelet-rich Fibrin dan Advanced Platelet-rich Fibrin Pl... by Ellia Stella, Komang Ardi Wahyuningsih

“…The new generation of PRF, namely advanced PRF plus (A-PRF+), has a different fibrin structure and more growth factors compared to Advanced PRF (A-PRF), the generation before A-PRF+. …”
Get full text

Performance of PRP Associated with Porous Chitosan as a Composite Scaffold for Regenerative Medicine by Andréa Arruda Martins Shimojo, Amanda Gomes Marcelino Perez, Sofia Elisa Moraga Galdames, Isabela Cambraia de Souza Brissac, Maria Helena Andrade Santana

“…The results showed the performance of the scaffolds was superior to that of activated platelet-rich plasma alone, in terms of delaying the release of growth factors and increased proliferation of the stem cells. …”
Get full text