Targeting heparan sulfate proteoglycans as an effective strategy for inhibiting cancer cell migration and invasiveness compared to heparin by Lorenzo Depau, Jlenia Brunetti, Chiara Falciani, Elisabetta Mandarini, Marta Zanchi, Maria Francesca Paolocci, Marta Garfì, Alessandro Pini, Luisa Bracci

“…By virtue of their ability to bind different growth factors, morphogens and extracellular matrix proteins, heparan sulfate proteoglycans (HSPGs) play a determinant role in cancer cell differentiation and migration. …”
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Regional Determinants of Efficiency Growth of Small and Medium-Sized Enterprises. Evidence from Poland by Teresa Łuczka, Paweł Przepióra

“…It is not surprisingly that the specified set of pro-growth factors does not exists. Next section describes the results of the author’s own studies in the fields. …”
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Advances in Meniscal Tissue Engineering by Umile Giuseppe Longo, Mattia Loppini, Francisco Forriol, Giovanni Romeo, Nicola Maffulli, Vincenzo Denaro

“…Current research efforts of tissue engineering try to combine cell-based therapy, growth factors, gene therapy, and reabsorbable scaffolds to promote healing of meniscal defects. …”
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Pituitary adenoma: important genetic factors and clinical diagnostic issues by G. Juknytė, E. Karinauskė, R. Liutkevičienė

“…It is thought to be a disease of multifactorial etiology, the occurrence of which is influenced by genetic factors, hormonal stimulation, and growth factors. PA can be inherited in an autosomal dominant manner. …”
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Calcium/Cobalt Alginate Beads as Functional Scaffolds for Cartilage Tissue Engineering by Stefano Focaroli, Gabriella Teti, Viviana Salvatore, Isabella Orienti, Mirella Falconi

“…These novel chondrogenesis-promoting scaffolds take advantage of the synergy between the alginate matrix and Co+2 ions, without employing costly growth factors (e.g., transforming growth factor betas (TGF-βs) or bone morphogenetic proteins (BMPs)) to direct hADSC differentiation into cartilage-producing chondrocytes.…”
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Human epicardial organoids from pluripotent stem cells resemble fetal stage with potential cardiomyocyte- transdifferentiation by Fanwen Wang, Xinle Zou, Huilin Zheng, Tianci Kong, Duanqing Pei

“…Meanwhile, extracellular matrix and growth factors secreted by epicardial organoid mimics the ecology of subepicardial space between the epicardium and cardiomyocytes. …”
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In Vivo Experiments with Dental Pulp Stem Cells for Pulp-Dentin Complex Regeneration by Sunil Kim, Su-Jung Shin, Yunjung Song, Euiseong Kim

“…While it is important to perform research on cells, scaffolds, and growth factors, it is also critical to develop animal models for preclinical trials. …”
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Advances and Challenges in Islet Transplantation: Islet Procurement Rates and Lessons Learned from Suboptimal Islet Transplantation by Annette Plesner, C. Bruce Verchere

“…To facilitate the engraftment of more robust islets suitable for combating the challenging isolation period and proinflammatory transplantation milieu, numerous approaches have been employed to prevent beta-cell dysfunction and death including immune modulation, prevention of apoptosis and hypoxia, as well as stimulation of growth factors, angiogenesis, and reinnervation. In addition to briefly discussing islet isolation procedures, procurement rates, and islet transplantation, the relevant literature pertaining to successful suboptimal islet transplantation is reviewed to provide insight into potential approaches to balance the limited supply of available donor islets.…”
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Physical Exercise as a Diagnostic, Rehabilitation, and Preventive Tool: Influence on Neuroplasticity and Motor Recovery after Stroke by Caroline Pin-Barre, Jérôme Laurin

“…Indeed, it reduces inflammatory processes and apoptotic marker expression, promotes brain angiogenesis and expression of some growth factors, and improves the activation of affected muscles during exercise. …”
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Biomaterials in Guided Bone and Tissue Regenerations: An Update by Reza Abdollahi Namanloo, Maedeh Ommani, Kamyar Abbasi, Mostafa Alam, Ashkan Badkoobeh, Mahdi Rahbar, Hadi Kokabi Arasteh, Emran Hajmohammadi, Reza Sayyad Soufdoost, Seyed Ali Mosaddad

“…Secondly, biomaterials are examined for their therapeutic uses such as growth factors, stem cells, and gene delivery vehicles. …”
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Glucose Deprivation Enhances the Antiproliferative Effects of Oral Hypoglycemic Biguanides in Different Molecular Subtypes of Breast Cancer: an in Vitro Study by Bardaweel Sanaa K., Alsalamat Husam A., Aleidi Shereen M., Bashatwah Rasha M.

“…Many of these studies experienced detrimental limitations, since they were conducted on cancer cells commonly grown in culture media consisting of extremely high concentrations of growth factors and glucose. The present study was aimed at exploring the antiproliferative effects of the commonly studied metformin and the less frequently reported phenformin oral hypoglycemic agents on different molecular subtypes of breast cancer under rich glucose and glucose deprived conditions. …”
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Gab Docking Proteins in Cardiovascular Disease, Cancer, and Inflammation by Yoshikazu Nakaoka, Issei Komuro

“…In mammals, the Gab proteins, consisting of Gab1, Gab2, and Gab3, are involved in the amplification and integration of signal transduction evoked by a variety of extracellular stimuli, including growth factors, cytokines, antigens, and other molecules. …”
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Promoting Articular Cartilage Regeneration through Microenvironmental Regulation by Kai Liu, Bingjun Zhang, Xiaoling Zhang

“…We find that regulating the opening of mechanosensitive ion channels, regulating the expression of HIF-1, delivering growth factors, and clearing senescent cells can promote the formation of articular cartilage regeneration microenvironment. …”
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Mechanisms of Inflammation in Proliferative Vitreoretinopathy: From Bench to Bedside by Stavros N. Moysidis, Aristomenis Thanos, Demetrios G. Vavvas

“…One such target is the indirect pathway of activation of platelet-derived growth factor receptor alpha (PDGRα), which plays an important role in PVR. …”
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Platelet-Rich Plasma Injection Modulates Inflammatory Cytokines in Temporomandibular Joint Disorders: A Cross-Sectional Study by Karar Abdulzahra Mahdi, Muhassad H. Al-Mudhafar, Dunya Malhan Hanweet

“…Conclusion: The decrease in TNF-α and IL-8 levels following PRP injection indicates a potential anti-inflammatory effect in TMDs. PRP’s growth factors may help reverse degenerative changes by promoting tissue regeneration and repair.…”
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A Fuzzy Ecosystem Benchmarking for Crowdfunding in Transport Sector by Gargi Pant Shukla, Santosh Kumar, Mukesh Kumar, Ankit Kumar, Manoj Chhetri

“…The sixteen identified growth factors for CF have been distributed in 5 levels in the ISM designed model. …”
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Androgenetic Alopecia: A Review by Sebastine Oseghae Oiwoh, Ademola Olusegun Enitan, Olubola Titilope Adegbosin, Adeolu Oladayo Akinboro, Emmanuel Olaniyi Onayemi

“…Key search words included each term like ‘androgenetic alopecia’, ‘androgenic alopecia’, ‘pattern baldness’ and ‘pattern hair loss’ AND each term like ‘epidemiology’, ‘pathophysiology’, ‘genetics’, ‘hormones’, ‘micronutrient’, ‘stress and inflammation’, ‘growth factors’, ‘clinical features’, ‘staging’, ‘cardiovascular associations’, ‘diagnosis’ and ‘management’ were used in the search. …”
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Conditioned medium derived from mesenchymal stem cells and spinal cord injury: A review of the current therapeutic capacities by Gholam Reza Kaka, Farrokh Modarresi

“…CM encompasses neuroprotective growth factors and cytokines, such as stem cell factor (SCF), vascular endothelial growth factor (VEGF), and glial cell line-derived neurotrophic factor (GDNF). …”
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Changes in Cytokines of the Bone Microenvironment during Breast Cancer Metastasis by Donna M. Sosnoski, Venkatesh Krishnan, William J. Kraemer, Courtenay Dunn-Lewis, Andrea M. Mastro

“…The complex bone microenvironment produces an ever changing array of cytokines and growth factors. In this study, we examined levels of MCP-1, IL-6, KC, MIP-2, VEGF, MIG, and eotaxin in femurs of athymic nude mice inoculated via intracardiac injection with MDA-MB-231GFP human metastatic breast cancer cells, MDA-MB-231BRMS1GFP, a metastasis suppressed variant, or PBS. …”
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Articular Cartilage Repair Using Marrow Stimulation Augmented with a Viable Chondral Allograft: 9-Month Postoperative Histological Evaluation by James K. Hoffman, Sandra Geraghty, Nicole M. Protzman

“…The chondral allograft is comprised of native viable chondrocytes, chondrogenic growth factors, and extracellular matrix proteins within the superficial, transitional, and radial zones of hyaline cartilage. …”
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