Influence of Poly(L-Lactic Acid) Nanofibers and BMP-2–Containing Poly(L-Lactic Acid) Nanofibers on Growth and Osteogenic Differentiation of Human Mesenchymal Stem Cells by Markus D. Schofer, Susanne Fuchs-Winkelmann, Christian Gräbedünkel, Christina Wack, Roland Dersch, Markus Rudisile, Joachim H. Wendorff, Andreas Greiner, Jürgen R. J. Paletta, Ulrich Boudriot

“…The initial down-regulation was not observed when BMP-2 was directly incorporated into PLLA nanofibers by electrospinning, indicating that growth factors like BMP-2 might survive the spinning process in a bioactive form.…”
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Slowly Delivered Icariin/Allogeneic Bone Marrow-Derived Mesenchymal Stem Cells to Promote the Healing of Calvarial Critical-Size Bone Defects by Tianlin Liu, Xin Zhang, Yuan Luo, Yuanliang Huang, Gang Wu

“…In in vitro cellular experiments, icariin at optimal concentration (10−6 mol/L) could significantly upregulate the osteogenesis- and angiogenesis-related genes and proteins, such as Runx2, ALP, osteocalcin, vascular endothelial growth factors, and fibroblast growth factors, as well as the mineralization of BMSCs. …”
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The Efficacy of Platelet-Rich Plasma in the Repair of Tympanic Membrane Perforation by Kudure Basavaraj Prashanth, Haraganahalli Anandappa Manjunatha, Prathvi P. Nayak

“… Introduction Platelet-rich plasma (PRP) contains high platelet concentration and growth factors that help in rapid wound healing, hemostasis, and decreased scarring. …”
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Application of evolutionary games to modeling carcinogenesis by Andrzej Swierniak, Michal Krzeslak

“…This review, although partly idiosyncratic, covers such major areas of cancer-related phenomena as production of cytotoxins, avoidance of apoptosis, production of growth factors, motility and invasion, and intra- and extracellular signaling. …”
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The Role of PDGFs and PDGFRs in Colorectal Cancer by Roberta M. Manzat Saplacan, Loredana Balacescu, Claudia Gherman, Romeo I. Chira, Anca Craiu, Petru A. Mircea, Cosmin Lisencu, Ovidiu Balacescu

“…PDGFs are important growth factors for normal tissue growth and division, with an important role in blood vessel formation. …”
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Neurobiology of Major Depressive Disorder by Rosa Villanueva

“…Clinically, descriptive gene and protein expression analysis and genetic and functional studies revised here show that individual alterations of a complex signaling network, which includes the hypothalamic-pituitary-adrenal axis; the production of neurotrophins and growth factors; the expression of miRNAs; the production of proinflammatory cytokines; and, even, the abnormal delivery of gastrointestinal signaling peptides, are able to induce major mood alterations. …”
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Combined Periodontal and Endodontic Management of Palatal Radicular Groove with Platelet-Rich Fibrin and Biodentine® by Arjun Hari Rijal, Bhageshwar Dhami, Pratistha Ghimire

“…Different treatment modalities are available for its management, such as periodontal flap surgery, endodontic management, sealing of PRG with various cements, bone graft procedure for intrabony defect, extraction with intentional replantation after sealing or removal of a PRG, and endodontic treatment as well as the use of various growth factors. Success of the therapy depends on the type, depth, and extent of PRG, presence or absence of intrabony defect, vitality of involved tooth, and types of materials used to seal PRG. …”
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Gastrointestinal myofibroblasts: role in regulation of physiological activity and reparation of gastro-intestinal tract by E. F. Barinov, O. N. Sulayeva

“…Thesefunctions are related to wide spectrum of myofibroblast secretory products, producing molecules of basal membrane, components of matrix and growth factors. Intestinal myofibroblasts are pacemakers for smooth myocytes of GIT, they modulate neurotransmission, participate in modulation of immune response, playing a critical role in reparation of erosions and ulcers of GIT.…”
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Small Bowel Review: Part II by ABR Thomson, JA Thomson, MJ Ropeleski, GE Wild

“…Topics discussed are enterocyte proliferation and growth factors; amino acids, peptides and allergies; motility; salt and water absorption and secretion – diarrhea; vitamins and minerals; early development and ageing of the intestine; and ethanol effects.…”
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Understanding the Mysterious M2 Macrophage through Activation Markers and Effector Mechanisms by Tamás Rőszer

“…These markers are transmembrane glycoproteins, scavenger receptors, enzymes, growth factors, hormones, cytokines, and cytokine receptors with diverse and often yet unexplored functions. …”
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Polycaprolactone for Hard Tissue Regeneration: Scaffold Design and In Vivo Implications by Fernanda Ramírez-Ruiz, Israel Núñez-Tapia, María Cristina Piña-Barba, Marco Antonio Alvarez-Pérez, Vincenzo Guarino, Janeth Serrano-Bello

“…In the last thirty years, tissue engineering (TI) has emerged as an alternative method to regenerate tissues and organs and restore their function by implanting specific lineage cells, growth factors, or biomolecules functionalizing a matrix scaffold. …”
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Dental Pulp Mesenchymal Stem Cells Attenuate Limb Ischemia via Promoting Capillary Proliferation and Collateral Development in a Preclinical Model by Youfeng Li, Yuning Zhang, Hua Wang, Chengfeng Sun, Dongmei Liu, Hongying Liu, Jia He, Furong Chen, Weiting Wang, Xi Jiang, Chu-tse Wu, Yuefeng Yang

“…In vitro experiments showed that serum deprivation improved the expression of angiogenic factors, growth factors, and chemokines in DP-MSCs and UC-MSCs, but not in BM-MSCs and AD-MSCs. …”
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Stem Cells for Augmenting Tendon Repair by Lawrence V. Gulotta, Salma Chaudhury, Daniel Wiznia

“…Specifically, the type of stem cell, the amount of cells, and the proper combination of growth factors or mechanical stimuli to induce differentiation all remain to be seen. …”
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Fine Tuning Cell Migration by a Disintegrin and Metalloproteinases by D. Dreymueller, K. Theodorou, M. Donners, A. Ludwig

“…The different steps of immune cell, tissue cell, or cancer cell migration are tightly coordinated in time and place by growth factors, cytokines/chemokines, adhesion molecules, and receptors for these ligands. …”
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Matrix Metalloproteinases in Inflammatory Bowel Disease: An Update by Shane O’Sullivan, John F. Gilmer, Carlos Medina

“…Studies of the involvement of MMPs in IBD since 2006 have revealed an array of immune and stromal cells which release the proteases in response to inflammatory cytokines and growth factors. Through digestion of the extracellular matrix and cleavage of bioactive proteins, a huge diversity of roles have been revealed for the MMPs in IBD, where they have been shown to regulate epithelial barrier function, immune response, angiogenesis, fibrosis, and wound healing. …”
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Nucleic Acid-Based Therapy Approaches for Huntington's Disease by Tatyana Vagner, Deborah Young, Alexandre Mouravlev

“…These approaches include increasing expression of growth factors, decreasing levels of mutant huntingtin, and restoring cell metabolism and transcriptional balance. …”
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The Role of Decorin in Autoimmune and Inflammatory Diseases by Yuanji Dong, Jixin Zhong, Lingli Dong

“…Decorin is involved in an extensive signaling network and can interact with other extracellular matrix components, growth factors, receptor tyrosine kinases, and various proteases. …”
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Enhancing IVF Success in Challenging Infertility Cases: The Role of PRGF, GH, and Endometrial Optimization by Sudhanshu Dakre, Jarul Shrivastava, Namrata Anjankar, Deepti Shrivastava, Aakash More, Shradha M. Ulhe

“…It included plasma-rich growth factors, growth hormone, supplementation along with some interventional support of endometrial scratching, and assisted hatching. …”
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Pathogenesis of Nonsteroidal Anti-Inflammatory Drug Gastropathy: Clues to Preventative Therapy by Salim MA Bastaki, John L Wallace

“…Acid impairs the restitution process, interferes with hemostasis and can inactivate several growth factors that are important in mucosal integrity and repair. …”
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Using Mathematical Modeling as a Resource in Clinical Trials by Evans K. Afenya

“…In the case of dose-dense treatment along with recombinant hematopoietic growth factors, the models predict a situation in which normal and abnormal cells in the marrow and peripheral blood are obliterated by drug action, while the normal cells regain their growth capabilities through growth-factor stimulation.…”
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