A clinical decision model for failed adrenal vein sampling in primary aldosteronism by Sophie N. M. ter Haar, Sofie J. van Goor, Eleonora P. M. Corssmit, Arian R. van Erkel, Bartholomeus E. P. B. Ballieux, Olaf M. Dekkers, Olaf M. Dekkers, Michiel F. Nijhoff

“…Adrenal vein sampling (AVS) is the gold standard for subtype differentiation but can be unsuccessful by challenging right adrenal vein anatomy. …”
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Induced mesenchymal stem cells generated from periodontal ligament fibroblast for regenerative therapy by Hemanathan Vembuli, Sheeja Rajasingh, Patrick Nabholz, Jefferson Guenther, Brian R. Morrow, Margaret M. Taylor, Marziyeh Aghazadeh, Vinoth Sigamani, Johnson Rajasingh, Johnson Rajasingh, Johnson Rajasingh

“…Despite autologous bone grafts remain the gold standard for treatment, challenges such as limited bone availability, immune reactions, and the risk of infectious disease transmission have driven the search for alternative cell-based therapies for bone regeneration. …”
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The Simulation of a Surface Plasmon Resonance Metallic Grating for Maximizing THz Sensitivity in Refractive Index Sensor Application by Asmar Sathukarn, Chia Jia yi, Sakoolkan Boonruang, Mati Horprathum, Khwanchai Tantiwanichapan, Kiattiwut Prasertsuk, Chayut Thanapirom, Woraprach Kusolthossakul, Kittipong Kasamsook

“…To demonstrate our methodology, we design a gold-coated grating with a polydimethylsiloxane (PDMS) as a substrate, in order to perform quantitative analysis of gasoline-toluene mixture composition, which has a refraction index variation of 0.1 at THz frequency. …”
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Utility of the Rose Bengal Test as a Point-of-Care Test for Human Brucellosis in Endemic African Settings: A Systematic Review by Abel B. Ekiri, Christopher Kilonzo, Brian H. Bird, Elizabeth VanWormer, David J. Wolking, Woutrina A. Smith, Honorati Masanja, Rudovick R. Kazwala, Jonna A.K. Mazet

“…The diagnostic sensitivity (DSe) and specificity (DSp) of RBT compared to culture as the gold standard were 87.5% and 100%, respectively, in studies that used suitable “true positive” and “true negative” patient comparison groups and were considered to be of high scientific quality. …”
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Pityriasis versicolor: insight into current knowledge and treatment possibilities by Jakub Parys, Agnieszka Mikosińska, Martyna Kaźmierczak, Patrycja Kałuziak, Maciej Mossakowski, Marta Jajczak, Aleksandra Witek, Stanisław Jesionek, Mateusz Litwin

“…Despite these advancements, a universally accepted gold standard for treatment remains undefined, and patient adherence often is a barrier to successful outcomes. …”
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Latent class cluster analysis of knowledge on acute myocardial infarction in community residents: a cross-sectional study in Tianjin, China by Jing Wang, Xu Zhang, Yan Zhang, Jing Ma, Nan Zhang, Yuan Wang, Jing Gao, Jian-yong Xiao, Yin Liu, Ji-xiang Wang, Xiao-wei Li, Ming-dong Gao, Jing-xian Wang, Shi-bo Xu

“…This study aimed to identify clusters of knowledge on symptoms and RFs of AMI, compare characteristics and the awareness of the need for prompt treatment.Design Multistage stratified sampling was used in this cross-sectional study. Latent GOLD Statistical Package was used to identify and classify the respondent subtypes of the knowledge on AMI symptoms or modifiable RFs. …”
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Comparative efficacy of conventional pap smear and liquid based cytology for screening of cervical cancer in women of reproductive age group in a tertiary care centre in rural Madh... by Shambhavi, Suresh Kumar Sutrakar, Lokesh Tripathi, Parul Singh Rajpoot, Priyanka Agrawal, Uday Raj Singh, Jagannath Jatav, Deepti Tiwari, Pushpkunjika Sharma

“…CPS, LBC (Ezyprep™), and colposcopy-guided biopsies were utilized, with histopathology as the gold standard. Statistical analysis involved sensitivity, specificity, and receiver operating characteristic curves. …”
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Gas-phase fractionation DDA promotes in-depth DIA phosphoproteome analysis by Zhiwei Tu, Yabin Li, Shuhui Ji, Shanshan Wang, Rui Zhou, Gertjan Kramer, Yu Cui, Fei Xie

“…Library-based DIA database searching against project-specific data-dependent acquisition (DDA) spectral libraries is the gold standard. These libraries are constructed using material-consuming pre-fractionation two dimensional DDA analysis. …”
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Clinical Laboratory Validation Study of a High Sensitivity Troponin I Assay on a POCT (Point of Care Testing) Device by Fabio Grunspun Pitta, Adriana Caschera Leme, Simone Rodrigues Gomes, Tarsila Perez Mota, Fernanda Vieira Paladino, José Leão de Souza Júnior, Rosemeire de Paula Braz, Thais Cristine Rodrigues Leonel Lamounier, Jéssica Buzin Gomes Ferreira, Carlos Eduardo dos Santos Ferreira

“…Background: In Acute Coronary Syndrome without ST-segment elevation, the use of high-sensitivity troponins in rapid protocols is considered the gold standard for diagnostic exclusion/confirmation, in conjunction with clinical stratification. …”
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A genomic strategy for precision medicine in rare diseases: integrating customized algorithms into clinical practice by Cristina Méndez-Vidal, Nereida Bravo-Gil, Javier Pérez-Florido, Irene Marcos-Luque, Raquel M. Fernández, José Luis Fernández-Rueda, María González-del Pozo, Marta Martín-Sánchez, Elena Fernández-Suárez, Marcela Mena, Rosario Carmona, Joaquín Dopazo, Salud Borrego, Guillermo Antiñolo

“…Abstract Background Despite the use of Next-Generation Sequencing (NGS) as the gold standard for the diagnosis of rare diseases, its clinical implementation has been challenging, limiting the cost-effectiveness of NGS and the understanding, control and safety essential for decision-making in clinical applications. …”
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Efficacy and safety of transanal endoscopic microsurgery for early rectal cancer: a meta-analysis by Chunqiang Wang, Tianye Huang, Xuebing Wang

“…BackgroundThe gold standard for the treatment of rectal cancer is radical surgery with total mesorectal excision (TME). …”
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Validity, Agreement and Reliability of the ForceFrame Dynamometer in Patients with Anterior Cruciate Ligament Injury by Kamilla Arp, Thomas Frydendal, Troels Kjeldsen, Ulrik Dalgas, Signe Timm, Bjarke Viberg, Kim Ingwersen, Claus Varnum

“…Day one included validity assessments with FF, a gold-standard ID and a handheld dynamometer (HHD). …”
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The use of bacterial culture for Leptospirosis di- agnosis in female water buffaloes by Rosaura Pérez-Gil, Oriana Gavidia, Juan Torres

“…The bacteriological culture of Leptospira spp. is the gold standard test because it can demonstrate the agent’s presence. …”
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Tratamento Farmacológico das Dimensões Sintomáticas da Perturbação de Personalidade Borderline: Recomendações Baseadas na Evidência by Carlos Siopa, Francisco Silva, Inês Souto Braz

“…Embora a psicoterapia seja o tratamento gold‑standard, o tratamento farmacológico torna‑se necessário em vários casos. …”
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Evaluating the feasibility, sensitivity, and specificity of next-generation molecular methods for pleural infection diagnosis by Peter T. Bell, Timothy Baird, John Goddard, Olusola S. Olagoke, Andrew Burke, Shradha Subedi, Tiana R. Davey, James Anderson, Derek S. Sarovich, Erin P. Price

“…However, we encountered challenges that complicated pleural infection interpretation, including: (i) uncertainties regarding microbial pathogenicity and the impact of prior antibiotic therapy on diagnostic performance; (ii) lack of a clinical diagnostic gold-standard for molecular performance comparisons; (iii) potential microbial contamination during specimen collection or processing; and (iv) difficulties distinguishing background microbial noise from true microbial signal in low-biomass specimens. …”
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Primary repair vs arthroscopic reconstruction for proximal anterior cruciate ligament tears: a comparative study by Sergey A. Gerasimov, Ekaterina A. Morozova, Daria A. Naida, Denis O. Kolmakov, Andrey A. Zykin, Ekaterina V. Khramtsova

“…Anterior cruciate ligament (ACL) reconstruction is the gold standard surgical option for ACL tears. Another treatment method is primary ACL repair. …”
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The value of metagenomic next-generation sequencing in the diagnosis of fever of unknown origin by Lan Min Lai, Qing-gen Chen, Yang Liu, Rui Zhao, Mei Ling Cao, Lei Yuan

“…The sensitivity and specificity of culture and mNGS were analyzed based on the final clinical diagnosis as the gold standard to assess the diagnostic value of mNGS in FUO cases. …”
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Targeting accuracy of neuronavigation: a comparative evaluation of an innovative wearable AR platform vs. traditional EM navigation by Marina Carbone, Marina Carbone, Nicola Montemurro, Nicola Montemurro, Nadia Cattari, Nadia Cattari, Martina Autelitano, Martina Autelitano, Fabrizio Cutolo, Fabrizio Cutolo, Vincenzo Ferrari, Vincenzo Ferrari, Emanuele Cigna, Emanuele Cigna, Sara Condino, Sara Condino

“…This study evaluates the benefits of a novel AR platform, VOSTARS, by comparing its targeting accuracy to that of the gold-standard electromagnetic (EM) navigation system, Medtronic StealthStation® S7®. …”
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Discovery and in vitro characterization of a human anti-CD36 scFv by Cecilia Mata-Cruz, Cecilia Mata-Cruz, Sandra L. Guerrero-Rodríguez, Keyla Gómez-Castellano, Gregorio Carballo-Uicab, Juan Carlos Almagro, Juan Carlos Almagro, S. Mayra Pérez-Tapia, S. Mayra Pérez-Tapia, S. Mayra Pérez-Tapia, Marco A. Velasco-Velázquez

“…Herein, we aimed to identify human anti-CD36 single-chain variable fragment (scFv) with therapeutic potential.MethodsThe semisynthetic ALTHEA Gold Plus Libraries™ were panned using recombinant human CD36. …”
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Effectiveness of Gastric Cancer Endoscopic Screening in Intermediate-Risk Countries: Protocol for a Systematic Review and Meta-Analysis by Maria Beatriz Mourato, Nuno Pratas, Andreia Branco Pereira, Filipa Taré, Raphael Chança, Inês Fronteira, Rui Dinis, Miguel Areia

“…Upper endoscopy with biopsy is the gold standard for GC diagnosis. Several studies have investigated the relevance of endoscopic screening and how to implemente it in IR countries. …”
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