Bismuth-Remaining Cupellation Fire Assay Preconcentration Combined with Inductively Coupled Plasma Mass Spectrometry for the Simultaneous Determination of Ultratrace Au, Pt, Pd, Ru... by Wenshan Ni, Xiangju Mao, Mingxing Yao, Qiliang Sun, Xiaorui Guo, Hongli Zhang, Lu Liu

“…In this work, a novel method of bismuth fire assay (Bi-FA) combined with inductively coupled plasma mass spectrometry (ICP-MS) simultaneous determination of ultratrace gold (Au), platinum (Pt), palladium (Pd), ruthenium (Ru), rhodium (Rh), and iridium (Ir) in geologic samples was established. …”
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New Platform Technology for Comprehensive Serological Diagnostics of Autoimmune Diseases by Annika Willitzki, Rico Hiemann, Vanessa Peters, Ulrich Sack, Peter Schierack, Stefan Rödiger, Ursula Anderer, Karsten Conrad, Dimitrios P. Bogdanos, Dirk Reinhold, Dirk Roggenbuck

“…However, detection of antinuclear antibodies by IIF is still recommended to be the gold standard method for antibody screening in sera from patients with suspected SARD. …”
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DeepRetention: A Deep Learning Approach for Intron Retention Detection by Zhenpeng Wu, Jiantao Zheng, Jiashu Liu, Cuixiang Lin, Hong-Dong Li

“…Here we present DeepRetention, a novel approach for IR detection by modeling the pattern of sequencing depth of introns. Due to the lack of a gold standard dataset of IR, we first compare DeepRetention with two state-of-the-art methods, i.e. iREAD and IRFinder, on simulated RNA-seq datasets with retained introns. …”
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Predicting the infecting dengue serotype from antibody titre data using machine learning. by Bethan Cracknell Daniels, Darunee Buddhari, Taweewun Hunsawong, Sopon Iamsirithaworn, Aaron R Farmer, Derek A T Cummings, Kathryn B Anderson, Ilaria Dorigatti

“…The plaque reduction neutralisation test (PRNT) is the gold standard assay for measuring serotype-specific antibodies, but this test cannot differentiate homotypic and heterotypic antibodies and characterising the infection history is challenging. …”
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Development and evaluation of a novel E7 multi-epitopic vaccine for human papillomavirus type 16: design, expression, purification, and immunological characterization by Bahareh Bahmani, Zahra Amini-bayat, Mohammad Mehdi Ranjbar, Masoud Hassanzadeh Makoui, Amir-Hassan Zarnani

“…Results Our study revealed that the final construct was successfully expressed in E. coli BL21 (DE3)-gold within 4 h of induction as inclusion bodies. …”
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Artificial intelligence as a transforming factor in motility disorders–automatic detection of motility patterns in high-resolution anorectal manometry by Miguel Mascarenhas, Francisco Mendes, Joana Mota, Tiago Ribeiro, Pedro Cardoso, Miguel Martins, Maria João Almeida, João Rala Cordeiro, João Ferreira, Guilherme Macedo, Cecilio Santander

“…Abstract High-resolution anorectal manometry (HR-ARM) is the gold standard for anorectal functional disorders’ evaluation, despite being limited by its accessibility and complex data analysis. …”
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Examining the Specificity of Smartphone ECG Devices in Decision-Making for ST-Elevation Myocardial Infarction and Non-ST-Elevation Myocardial Infarction by Sahil mahajan, Salil Garg, Yogendra Singh, richa sharma, Tanuj Bhatia, nitin chandola, deeksha agarwal

“…Utilizing smartphone ECG devices as the index, 12-lead ECG tests were administered alongside the Gold Standard ECG machine for comparison among patients in CCUs and CICUs. …”
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Diagnostic Performance between Histidine-Rich Protein 2 (HRP-2), a Rapid Malaria Diagnostic Test and Microscopic-Based Staining Techniques for Diagnosis of Malaria by Jean Baptiste Niyibizi, Emmanuel Kamana Gatera

“…Microscopy remains the gold standard for diagnosing malaria, but it is labor intensive and depends upon the skill of the examiner. …”
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Enhancing cardiac assessments: accurate and efficient prediction of quantitative fractional flow reserve by Arshia Eskandari, Sara Malek, Alireza Jabbari, Kian Javari, Nima Rahmati, Behrad Nikbakhtian, Bahram Mohebbi, Seyed Ehsan Parhizgar, Mona Alimohammadi

“…Invasive Fractional flow reserve (FFR) is the gold standard for Coronary Artery Disease risk assessment. …”
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METHODOLOGY FOR DATA COLLECTION IN SIMULATED IRRADIATIONS USING MONTE CARLO TECHNIQUES ON DICOM IMAGES FOR X-RAY FLUORESCENCE EMISSIONS LOCALIZATION IN HIGH ATOMIC NUMBER MATERIALS by Nicolás E. Martín, F. Malano, Miguel Sofo Haro, M. Valente

“…This approach allows for simultaneous transmission computed tomography (CT) along with XFCT, providing multimodal/multiplexed in vivo images and expanding applications with metallic probes such as gold nanoparticles (AuNPs). Despite its benefits, CT+XFCT imaging poses challenges, particularly in minimizing X-ray dose. …”
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Analytical and diagnostic performance characteristics of reverse-transcriptase loop-mediated isothermal amplification assays for dengue virus serotypes 1-4: A scoping review to inf... by Paul Arkell, Dumrong Mairiang, Adisak Songjaeng, Kenny Malpartida-Cardenas, Kerri Hill-Cawthorne, Panisadee Avirutnan, Pantelis Georgiou, Alison Holmes, Jesus Rodriguez-Manzano

“…Reverse-transcriptase (RT) quantitative polymerase chain reaction (qPCR) assays are the current gold-standard in diagnosis and serotyping of infections, but their use in low-middle income countries (LMICs) has been limited by laboratory infrastructure requirements. …”
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Diagnosis of Obstructive Sleep Apnea in Parkinson’s Disease Patients: Is Unattended Portable Monitoring a Suitable Tool? by Priti Gros, Victoria P. Mery, Anne-Louise Lafontaine, Ann Robinson, Andrea Benedetti, R. John Kimoff, Marta Kaminska

“…Polysomnography (PSG) is the gold standard for OSA diagnosis. Unattended portable monitoring (PM) may improve access to diagnosis but has not been studied in PD. …”
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Monitoring for 5-aminosalicylate nephrotoxicity in adults with inflammatory bowel disease: prognostic model development and validation using data from the Clinical Practice Researc... by Abhishek Abhishek, Richard D Riley, Christian D Mallen, Guruprasad P Aithal, Georgina Nakafero, Matthew J Grainge, Maarten W Taal, Tim Card, Matthew D Stevenson

“…Objective To develop and validate a prognostic model for risk-stratified monitoring of 5-aminosalicylate nephrotoxicity.Methods This UK retrospective cohort study used data from the Clinical Practice Research Datalink Aurum and Gold for model development and validation respectively. …”
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Usefulness of Multidetector Row Computed Tomography for Predicting Cardiac Events in Asymptomatic Chronic Kidney Disease Patients at the Initiation of Renal Replacement Therapy by Jung Eun Lee, Yong Kyu Lee, Eun Jeong Choi, Ji Sun Nam, Byoung Wook Choi, Beom Seok Kim

“…Although coronary angiography is the gold standard in diagnosing CAS its invasiveness and economic burden lead to searching for a noninvasive alternative method. …”
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Neutrophil Gelatinase-Associated Lipocalin: A New Marker of Renal Function in C-Related End Stage Liver Disease by Omkolsoum Mohamed Alhaddad, Ayman Alsebaey, Mohamed Omar Amer, Hala Hany El-Said, Tary Abdel Hamid Salman

“…Measurement of the glomerular filtration rate (GFR) is the gold standard but time consuming. The aim is to validate plasma NGAL (pNGAL) and urinary NGAL (uNGAL) as markers of renal function in patients with HCV related cirrhosis. …”
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Automated Indirect Immunofluorescence Evaluation of Antinuclear Autoantibodies on HEp-2 Cells by Jörn Voigt, Christopher Krause, Edda Rohwäder, Sandra Saschenbrecker, Melanie Hahn, Maick Danckwardt, Christian Feirer, Konstantin Ens, Kai Fechner, Erhardt Barth, Thomas Martinetz, Winfried Stöcker

“…Indirect immunofluorescence (IIF) on human epithelial (HEp-2) cells is considered as the gold standard screening method for the detection of antinuclear autoantibodies (ANA). …”
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Anti-VEGF therapy for diabetic macular edema: up-to-date approaches to the management of patients with high and low baseline functional parameters by E.V. Bobykin

“…There is no doubt that the key role is played by anti-angiogenic (anti-VEGF) therapy which has become the gold standard treatment for DME and is supported by a strong evidence base. …”
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Total synthesis and target identification of marine cyclopiane diterpenes by Tian Li, Shan Jiang, Yuanhao Dai, Xia Wu, Huihui Guo, Liang Shi, Xueli Sang, Li Ren, Jie Wang, Lili Shi, Wenming Zhou, Houhua Li, Hong-Dong Hao

“…Our asymmetric synthesis commences from Wieland-Miescher ketone and features a sequential intramolecular Pauson-Khand reaction and gold-catalyzed Nazarov cyclization to rapidly construct the 6-5-5-5 tetracyclic skeleton. …”
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Tongue squamous cell carcinoma-targeting Au-HN-1 nanosystem for CT imaging and photothermal therapy by Ming Hao, Xingchen Li, Xinxin Zhang, Boqiang Tao, He Shi, Jianing Wu, Yuyang Li, Xiang Li, Shuangji Li, Han Wu, Jingcheng Xiang, Dongxu Wang, Weiwei Liu, Guoqing Wang

“…However, inadequate accumulation of photosensitizers at the tumor site diminishes the efficacy of photothermal therapy (PTT). This study modified gold nanodots (AuNDs) with the TSCC-targeting peptide HN-1 to improve the selectivity and therapeutic effects of PTT. …”
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Identification and characterization of the functional tetrameric UDP-glucose pyrophosphorylase from Klebsiella pneumoniae by Isabel Ramón Roth, Pavel Kats, Timm Fiebig, Françoise Routier, Roman Fedorov, Larissa Dirr, Jana I. Führing

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