PEGDA-based HistoBrick for increasing throughput of cryosectioning and immunohistochemistry in organoid and small tissue studies by Emilie Vuille-dit-Bille, Larissa Utz, Fiona E. Müllner, Valeria J. Arteaga-Moreta, Yanyan Hou, Stefan E. Spirig, Diane Ledroit-Paic, Sarah Heub, Jonas Goldowsky, Gilles Weder, Magdalena Renner

“…Abstract Histology is the gold standard for analyzing tissue structure and cell morphology. …”
Get full text

The Basas Spanish Squat: Superimposition of Electrical Stimulation to Optimize Patellar Tendon Strain: A Case Series by Carlos Basas, Naoaki Ito, Karin Grävare Silbernagel, Fernando Reyes-Gil, Ángel Basas

“…# Background The Basas Spanish Squat with electrical stimulation (E-stim) has shown promising results as a potential key exercise in treatment of athletes with patellar tendinopathy. Gold standard exercise therapy for tendon injuries consists of tendon loading exercises, or exercises that appropriately applies high levels of mechanical strain to the tendon. …”
Get full text

Diabetic Macular Edema Pathophysiology: Vasogenic versus Inflammatory by Pedro Romero-Aroca, Marc Baget-Bernaldiz, Alicia Pareja-Rios, Maribel Lopez-Galvez, Raul Navarro-Gil, Raquel Verges

“…DM parameters controls (glycemia, arterial tension, and lipids) are the gold standard for preventing DR and DME. Although the vascular endothelial growth factor (VEGF) is known to play a role in the development of DME, the pathological processes leading to the onset of this disease are highly complex and the exact sequence in which they occur is still not completely understood. …”
Get full text

Immunotherapies to Nano-Immunotherapies: Advances in Immune Targeting in Bladder Cancer by Beatriz Ramos, Dakota Rogers

“…Recent advances include the use of gold nanoparticles, TLR agonist-loaded nanoparticles, and exosome-based delivery systems to boost immune responses. …”
Get full text

On inflation in the Russian economy by A. I. Bolonin

“…During the time of the gold standard and bimetallism regulation of the economy as a whole was not considered as an important macroeconomic problem. …”
Get full text

Pangenome Analysis of Helicobacter pylori Isolates from Selected Areas of Africa Indicated Diverse Antibiotic Resistance and Virulence Genes by Biigba Yakubu, Edwin Moses Appiah, Andrews Frimpong Adu

“…The challenge facing Helicobacter pylori (H. pylori) infection management in some parts of Africa is the evolution of drug-resistant species, the lack of gold standard in diagnostic methods, and the ineffectiveness of current vaccines against the bacteria. …”
Get full text

Health Canada's use of its priority review process for new drugs: a cohort study by Joel Lexchin

“…The purpose of this study is to compare Health Canada's use of priority reviews to therapeutic ratings from two independent organisations, the Patented Medicine Prices Review Board (PMPRB) and the French drug bulletin Prescrire International, over the period 1 January 1997–31 December 2012.Design Cohort study.Data sources Annual reports of the Therapeutic Products Directorate, and the Biologics and Genetic Therapies Directorate; evaluations of therapeutic innovation from PMPRB and Prescrire International; WHO Collaborating Centre for Drug Statistics Methodology.Interventions Assessments by PMPRB and Prescrire International treated as a gold standard for postmarket therapeutic value.Primary and secondary outcome measures Drug-by-drug comparison between the review status from Health Canada and the therapeutic status from PMPRB/Prescrire using κ values, and positive and negative predictive values. …”
Get full text

Mesenchymal Stem Cells for the Treatment of Spinal Arthrodesis: From Preclinical Research to Clinical Scenario by F. Salamanna, M. Sartori, G. Barbanti Brodano, C. Griffoni, L. Martini, S. Boriani, M. Fini

“…The use of spinal fusion procedures has rapidly augmented over the last decades and although autogenous bone graft is the “gold standard” for these procedures, alternatives to its use have been investigated over many years. …”
Get full text

Electrochemical Study of Carbon Nanotubes/Nanohybrids for Determination of Metal Species Cu2+ and Pb2+ in Water Samples by Andréa Claudia Oliveira Silva, Luis Carlos Ferreira de Oliveira, Angladis Vieira Delfino, Mario Roberto Meneghetti, Fabiane Caxico de Abreu

“…The glassy carbon electrode modified by gold nanoparticles demonstrated increased sensitivity and decreased detection limits, among other improvements in analytical performance data. …”
Get full text

Defining the Pros and Cons of Open, Conventional Laparoscopy, and Robot-Assisted Pyeloplasty in a Developing Nation by Mrinal Pahwa, Archna R. Pahwa, Mohit Girotra, Rtika Ryfka Abrahm, Sachin Kathuria, Ajay Sharma

“…Historically, open dismembered pyeloplasty has been considered the gold standard intervention for correcting PUJO. The aim of this study was to compare the surgical and functional outcomes of three different approaches, namely, open, conventional laparoscopy, and robotic pyeloplasty. …”
Get full text

Challenges in Laboratory Diagnosis of Malaria in a Low-Resource Country at Tertiary Care in Eastern Nepal: A Comparative Study of Conventional vs. Molecular Methodologies by Pragyan Dahal, Basudha Khanal, Keshav Rai, Vivek Kattel, Satish Yadav, Narayan Raj Bhattarai

“…Considering real-time PCR as the gold standard method, microscopy had a sensitivity of 21.4% and a specificity of 100%, and the RDT had a sensitivity of 28.6% and a specificity of 92.1%. …”
Get full text

A Solution to the Time-Dependent Stress Distribution in Suborbicular Backfilled Stope Interaction with Creeping Rock by Baoxu Yan, Xingping Lai, Hanwen Jia, Erol Yilmaz, Chen Hou

Get full text

A Novel Classification of Uncertain Stream Data using Ant Colony Optimization Based on Radial Basis Function by Tahsin Ali Mohammed Amin, Sabah Robitan Mahmood, Rebar Dara Mohammed, Pshtiwan Jabar Karim

“…Error metrics show that our model significantly outperforms the gold standard and other popular ML methods. Using industry-standard performance metrics, the results of our experiments show that our proposed method does a better job of classifying uncertain data than other methods …”
Get full text

Phytotherapeutics and Probiotics as an Alternative to the Use of Antimicrobials in the Diets of Laying Quails by J Zanella, JK Valentim, AA Almeida, RG Garcia, CM Komiyama, PH Braz, MFC Burbarelli, FC Serpa, FR Caldara, BB Przybulinski, VARC Heiss, DD Moraleco

“…Conducted over 42 days with 300 quails, starting at 21 days of age and an average weight of 87 ± 3.5 g, the quails were divided into five groups: negative control (no additives), commercial antibiotics, probiotics (BS Gold®), essential oils (Phyto 100®), and natural pollen. …”
Get full text

Care home resident identification: A comparison of address matching methods with Natural Language Processing. by Víctor Suárez-Paniagua, Arlene Casey, Charis A Marwick, Jennifer K Burton, Helen Callaby, Isobel Guthrie, Bruce Guthrie, Beatrice Alex

“…Performance was evaluated in a diagnostic test study comparing NLP prediction to independent, gold-standard manual identification of care home addresses. …”
Get full text

Comparative Analysis of Hemagglutination Inhibition and Plaque Reduction Neutralization Tests for Japanese Encephalitis Virus Antibody Detection by Cui Li, Jianqing Wan, Deli Wang, Lu Xiao, Xuni Li, Cunshuai Zhang, Zhao Wang

“…The Plaque Reduction Neutralization Test (PRNT) is considered the gold standard for detecting JE-specific antibodies because of its high specificity. …”
Get full text

When Hysteroscopy is the only way out; a case series of endometrial osseous metaplasia by John Imaralu, Taiwo Solaja, Oluwole Ayegbusi, Olukemi Grillo, Remilekun Atunrase-Sotola, Theophilus Elejere

“… Background: Endometrial osseous metaplasia (EOM) poses diagnostic and treatment dilemmas. Hysteroscopy is the gold standard in the diagnosis of endometrial pathologies and offers optimal treatment for osseous metaplasia. …”
Get full text

Assessment of Accuracy of Linear Alveolar Ridge Measurements with Different Implant Planning Software Programs by S Savita, Neha Bhutani, Syed Zakaullah, Ramesh Chowdhary, Deepak Kumar, Farha Naaz

“…Hence, our study was done with the aim to compare the reliability of available software systems along with gold standard of ridge mapping using bone caliper. …”
Get full text

Clinical evidence based review and systematic scientific review in the identification of malignant transformation of inverted papilloma by Cai Long, Basel Jabarin, Alexandra Harvey, Jennifer Ham, Amin Javer, Arif Janjua, Andrew Thamboo

“…Conclusion Endoscopy with biopsy is the gold standard practice to identify IP-SCC; however, MRI is the preferred imaging modality to recognize malignant transformation in cases where biopsy is difficult. …”
Get full text

Sustainable Leaching of Cu, Ni, and Au from Waste Printed Circuit Boards Using Choline Chloride-Based Deep Eutectic Solvents by Sara Saffaj, Diego Mantovani, Georgios Kolliopoulos

“…., copper (Cu) and nickel (Ni), and precious metals, i.e., gold (Au), from waste printed circuit boards (PCBs). …”
Get full text