The Role of PPARs in Placental Immunology: A Systematic Review of the Literature by Stefan Hutter, Julia Knabl, Ulrich Andergassen, Udo Jeschke

“…Besides abortion as possible result of improper early pregnancy development, other pregnancy associated conditions like preeclampsia (PE), intrauterine growth retardation (IUGR), preterm labour, or gestational diabetes mellitus (GDM) are linked to immunologic overactivation and dysregulation. …”
Get full text

Epigenetic regulation in female reproduction: the impact of m6A on maternal-fetal health by Peipei Li, Yumeng Lin, Hongyun Ma, Jiao Zhang, Qiaorui Zhang, Ruihua Yan, Yang Fan

“…At present, researchers have found that m6A is involved in the regulation of gestational diabetes and other reproductive system diseases, but the specific mechanism is not clear. …”
Get full text

Understanding Patient Registries for Diabetes: A Scoping Review of Published Literature by Lana Moayad MD(C), Paige Alliston RD, MHSc, Saira Khalid BScN, Donna Fitzpatrick-Lewis MSW, Hertzel C. Gerstein MD, MSc, Diana Sherifali RN, PhD

“…Methods: We searched Pubmed, MEDLINE, Embase, and Emcare using the following criteria: (1) the population is people with diabetes mellitus, including type 1, type 2, and/or gestational diabetes; and (2) the study describes a patient focused registry. …”
Get full text

Future Directions: Analyzing Health Disparities Related to Maternal Hypertensive Disorders by Margaret Harris, Colette Henke, Mary Hearst, Katherine Campbell

“…Factors that influence the prevalence of maternal hypertensive disorders among racially and ethnically diverse women include maternal age, level of education, United States-born status, nonmetropolitan residence, prepregnancy obesity, excess weight gain during pregnancy, and gestational diabetes. Examination of the factors that increase the risk for maternal hypertensive disorders along with the current interventions utilized to manage hypertensive disorders will assist in the identification of gaps in prevention and treatment strategies and implications for future practice. …”
Get full text

Maternal–Foetal Effects of Exposure to Bisphenol A: Outcomes and Long-Term Consequences by Henrique Eloi Costa, Ines Medeiros, Melissa Mariana, Elisa Cairrao

“…Furthermore, in mothers, BPA exposure may be linked to pre-eclampsia and gestational diabetes mellitus and affects birth parameters, leading to a higher risk of preterm delivery, shorter birth lengths and lower birth weights, although the results were not always consistent. …”
Get full text

Low Grade Islet but Marked Exocrine Pancreas Inflammation in an Adult with Autoimmune Pre-Diabetes by Hiroshi Nomoto, Tatyana Gurlo, Madeline Rosenberger, Mark D. Girgis, Sarah Dry, Peter C. Butler

“…The patient had gestational diabetes at age 29 and has a 23 year old sister with T1D. …”
Get full text

Prevalence and Factors Associated with Preterm Birth in Urban Areas: Case-Control Study by Rozhan Khezri, Shaker Salarilak, Sepideh Jahanian

“…Multivariable logistic regression analysis revealed a significant association between PTB and the following factors: education levels, antenatal care (ANC) visits [Adjusted Odds Ratio (AOR)=7.91 (95% CI: 2.43–25.71)], premature rupture of membranes (PROM) [AOR=5.25 (95% CI: 2.01–13.74)], gestational diabetes mellitus (GDM) [AOR=5.27 (95% CI: 1.49–18.58)], and preeclampsia [AOR=9.47 (95% CI: 3.02–29.73)].Conclusion: Identifying pregnant women at risk of preterm birth is crucial, and treatments are available to reduce the risk. …”
Get full text

Endothelial Function in Women with and without a History of Glucose Intolerance in Pregnancy by Shireen Brewster, John Floras, Bernard Zinman, Ravi Retnakaran

“…Background/Aims. Gestational diabetes mellitus (GDM) and milder gestational impaired glucose tolerance (GIGT) identify women who are at risk of developing cardiovascular disease. …”
Get full text

Gestation complications in women with metabolic syndrome: pathogenesis, diagnosis and prevention (literature review) by L.P. Shelestova, L.F. Ushullu

“…It has been proven that the components of metabolic syndrome are associated with the development of pregnancy complications, such as pre-eclampsia, fetal growth retardation and macrosomia, gestational diabetes, preterm labour, fetal death, habitual early termination of pregnancy. …”
Get full text

Does remote COVID infection in pregnancy affect the placenta and pregnancy outcomes? – Results from a prospective cohort study (PLACENTA IN COVID/ PIC study) by N D Varunashree, Sherin Daniel, Swati Rathore, Mahesh Moorthy, Bijesh Yadav, Manisha M. Beck

“…Among those infected in the third trimester, 93% were symptomatic. Gestational Diabetes was the most common associated medical condition. . …”
Get full text

Research update on the effects of probiotic supplementation during pregnancy on pregnancy complications: a systematic literature review by Jing YANG, Xiaochuan WANG, Borui LIU, Xiaoyan ZHANG, Xiaoyu GAO, Jiajin HU

“…This review aims to summarize the potential effects of probiotic supplementation during pregnancy on common pregnancy complications, including gestational diabetes mellitus, preeclampsia, intrahepatic cholestasis of pregnancy, premature birth and spontaneous abortion, due to the current limitations in clinical research on probiotics and the heterogeneity of existing findings. …”
Get full text

Risk factors for type 2 diabetes mellitus in adolescentes by Wendy Valdés Gómez, Arianna Almirall Sánchez, Miguel Ángel Gutiérrez Pérez

“…Variables such as age, sex, history of gestational diabetes, low birth weight, breastfeeding time, family history of DM2, fruit / vegetable intake, physical activity and physical examination results were collected. …”
Get full text

Association between Prenatal One-Hour Glucose Challenge Test Values and Delivery Mode in Nondiabetic, Pregnant Black Women by Jerel M. Ezell, Rosalind M. Peters, Jessica E. Shill, Andrea E. Cassidy-Bushrow

“…At ~28 weeks of gestation, participants underwent a routine 1-hour 50 g GCT to screen for gestational diabetes mellitus. Logistic regression was used to examine the association between 1-hour GCT value and delivery mode. …”
Get full text

Gestational Weight Gain among Healthy Pregnant Women from Asia in Comparison with Institute of Medicine (IOM) Guidelines-2009: A Systematic Review by Priyanka Arora, Bani Tamber Aeri

“…The most common fetal-maternal complications among the excessive GWG women were found to be macrosomia, large for gestational age and caesarean section followed by gestational diabetes and hypertension, whereas low birth weight, small for gestational age and preterm birth, was found to be associated with low GWG women. …”
Get full text

Congenital malformations in children of diabetic mothers in the province of Cienfuegos. 2016-2019 by Fanny Arbolay Sanabria, Lázaro Roberto Herrera Fragoso, Maylé Santos Solí, Gladys Bárbara Barberis Pérez, Walkiria Díaz Senra, María Soledad Vilches León

“…<br /><strong>Results:</strong> in the studied population the highest percentage of mothers presented gestational diabetes mellitus; Mothers between 20 and 35 years old predominated and a large number of them were overweight. …”
Get full text

The Effectiveness of Myo-Inositol and D-Chiro Inositol Treatment in Type 2 Diabetes by Basilio Pintaudi, Giacoma Di Vieste, Matteo Bonomo

“…Inositol has been used as a supplement in treating several pathologies such as PCOS, metabolic syndrome, and gestational diabetes. Both myo-inositol and its isomer d-chiro-inositol showed insulin mimetic effects in conditions of insulin resistance. …”
Get full text

Health Care Consumption during Pregnancy in relation to Maternal Body Mass Index: A Swedish Population Based Observational Study by Elisabeth S. Lindholm, Daniel Altman, Margareta Norman, Marie Blomberg

“…Preeclampsia was more than four times as common, hypertension five times as common, and gestational diabetes 11 times as common when comparing in-patient care, obese to normal weight women (p<0.001 for all comparisons). …”
Get full text

Integrated Analysis Identifies Four Genes as Novel Diagnostic Biomarkers Which Correlate with Immune Infiltration in Preeclampsia by Mu-yi Yang, Ming-hui Ji, Tian Shen, Lei Lei

“…Diseases enriched by DEGs were mainly related to preeclampsia, gestational diabetes, ovarian disease, female reproductive system disease, and endocrine system disease. …”
Get full text

Wolfram Syndrome: A Case Report and Review of Clinical Manifestations, Genetics Pathophysiology, and Potential Therapies by N. B. Toppings, J. M. McMillan, P. Y. B. Au, O. Suchowersky, L. E. Donovan

“…We describe a woman without risk factors for gestational or type 2 diabetes who presented with gestational diabetes (GDM) at the age of 39 years during her first and only pregnancy. …”
Get full text

Body Mass Index and Gestational Weight Gain Are Associated with Maternal and Neonatal Outcomes Based on Chinese Women by Tingzhao Wang, Lichun Li, Chunchun Wu, Rong Cao, Qingli Li, Liji Yu, Youguo Chen

“…In the obese group, the risk of adverse maternal and neonatal outcomes (OR: 5.760, 95% CI: 1.997-16.786), maternal complications (OR: 3.112, 95% CI: 1.645-5.887), gestational diabetes mellitus (GDM) (OR: 2.943, 95% CI: 1.509-5.741), cesarean section (OR: 1.899, 95% CI: 1.002-3.599), and preterm delivery (OR: 4.752, 95% CI: 1.395-16.185) increased. …”
Get full text