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1001
Connecting genomic results for psychiatric disorders to human brain cell types and regions reveals convergence with functional connectivity
Published 2025-01-01“…Abstract Identifying cell types and brain regions critical for psychiatric disorders and brain traits is essential for targeted neurobiological research. By integrating genomic insights from genome-wide association studies with a comprehensive single-cell transcriptomic atlas of the adult human brain, we prioritized specific neuronal clusters significantly enriched for the SNP-heritabilities for schizophrenia, bipolar disorder, and major depressive disorder along with intelligence, education, and neuroticism. …”
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1002
Comparative Analysis of the Full-Length Genome Sequence of a Clinical Isolate of Human Parainfluenza Virus 4B
Published 2012-01-01“…The hPIV-4B genomic sequence that we determined conforms to the paramyxovirus “rule of six.” …”
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1003
Whole genome sequence of Streptomyces colonosanans strain MUSC 93JT isolated from mangrove forest in Malaysia
Published 2020-03-01“…Due to these data, the strain was subjected to whole genome sequencing to uncover its genomic potential and further improve the understanding of the strain. …”
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1004
Genome-wide transcriptome analysis and drug target discovery reveal key genes and pathways in thyroid cancer metastasis
Published 2025-02-01“…However, the mechanisms are still poorly understood. MethodsWe performed genome-wide transcriptome analysis comparing gene expression profile of metastatic thyroid cancer cells (Met) with primary tumor cells established from transgenic mouse models of papillary thyroid cancer (PTC), follicular thyroid cancer (FTC), poorly differentiated thyroid cancer (PDTC), and anaplastic thyroid cancer (ATC).ResultsGenes involved in tumor microenvironment (TME), inflammation, and immune escape were significantly overexpressed in Met cells. …”
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1005
Genomic analysis and potential polyhydroxybutyrate (PHB) production from Bacillus strains isolated from extreme environments in Mexico
Published 2025-01-01Subjects: Get full text
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1006
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1007
Flanking monomer repeats define lower context complexity of sites containing single nucleotide polymorphisms in the human genome
Published 2016-01-01Subjects: Get full text
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1008
Replication of Interactions between Genome-Wide Genetic Variants and Body Mass Index in Fasting Glucose and Insulin Levels
Published 2014-12-01“…Genomics & Informatics…”
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1009
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1010
Genome-Wide Approach Identifies Natural Large-Fragment Deletion in ASFV Strains Circulating in Italy During 2023
Published 2025-01-01“…In addition, an in vivo experiment in pigs was performed. Complete genomic sequencing of 30 strains revealed large-fragment deletions and translocations. …”
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1011
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1012
Machine learning methods for predicting essential metabolic genes from Plasmodium falciparum genome-scale metabolic network.
Published 2024-01-01“…It assessed various network properties in Plasmodium falciparum, using a Genome-Scale Metabolic Model (iAM_Pf480) from the BiGG database and essentiality data from the Ogee database. …”
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1013
Complete Genomic Landscape Reveals Hidden Evolutionary History and Selection Signature in Asian Water Buffaloes (Bubalus bubalis)
Published 2025-01-01Subjects: Get full text
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1014
Comparative genomic study of the Penicillium genus elucidates a diverse pangenome and 15 lateral gene transfer events
Published 2023-02-01“…The comprehensive characterization of the genomic diversity in the Penicillium genus supersedes single-reference genomes, which do not necessarily capture the entire genetic variation.…”
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1015
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1016
Florfenicol Resistance in Enterobacteriaceae and Whole-Genome Sequence Analysis of Florfenicol-Resistant Leclercia adecarboxylata Strain R25
Published 2019-01-01“…International Journal of Genomics…”
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1017
Genomic signatures of habitat isolation and paleo-climate unveil the “island-like” pattern in the glasshouse plant Rheum nobile
Published 2025-04-01“…The Himalaya and the Hengduan Mountains, known for their ‘Sky Islands’ ecosystems, offer a unique opportunity to study genomic differentiation of endemic plants. While there is growing research on the genetic mechanisms underlying the distinctiveness of species in these regions, gaps remain in understanding the specific genomic processes shaping the “island-like” genetic structure of Rheum nobile. …”
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1018
A Genomic‐Based Workflow for eDNA Assay Development for a Critically Endangered Turtle, Myuchelys georgesi
Published 2025-01-01Subjects: Get full text
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1019
Genome skimming provides evidence to accept two new genera (Apiaceae) separated from the Peucedanum s.l.
Published 2025-01-01“…Therefore, we conducted a comprehensive taxonomic revision of taxa within the polyphyletic Peucedanum s.l. genus in this study.MethodsWe used two molecular datasets (103 plastomes and 43 nrDNA sequences) generated by genome skimming to reconstructed a reliable phylogenetic framework with high support and resolution. …”
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1020
Detection of inversion with breakpoints in ARSB causing MPS VI by whole-genome sequencing: lessons learned and best practices
Published 2025-01-01Subjects: Get full text
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