Showing 1,001 - 1,020 results of 6,564 for search '"genomic"', query time: 0.08s Refine Results
  1. 1001

    Connecting genomic results for psychiatric disorders to human brain cell types and regions reveals convergence with functional connectivity by Shuyang Yao, Arvid Harder, Fahimeh Darki, Yu-Wei Chang, Ang Li, Kasra Nikouei, Giovanni Volpe, Johan N. Lundström, Jian Zeng, Naomi R. Wray, Yi Lu, Patrick F. Sullivan, Jens Hjerling-Leffler

    Published 2025-01-01
    “…Abstract Identifying cell types and brain regions critical for psychiatric disorders and brain traits is essential for targeted neurobiological research. By integrating genomic insights from genome-wide association studies with a comprehensive single-cell transcriptomic atlas of the adult human brain, we prioritized specific neuronal clusters significantly enriched for the SNP-heritabilities for schizophrenia, bipolar disorder, and major depressive disorder along with intelligence, education, and neuroticism. …”
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  2. 1002

    Comparative Analysis of the Full-Length Genome Sequence of a Clinical Isolate of Human Parainfluenza Virus 4B by John A. Lednicky, Thomas B. Waltzek, Micah D. Halpern, Sara B. Hamilton

    Published 2012-01-01
    “…The hPIV-4B genomic sequence that we determined conforms to the paramyxovirus “rule of six.” …”
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  3. 1003

    Whole genome sequence of Streptomyces colonosanans strain MUSC 93JT isolated from mangrove forest in Malaysia by Hooi-Leng Ser, Jodi Woan-Fei Law, Wen-Si Tan, Wai-Fong Yin, Kok-Gan Chan

    Published 2020-03-01
    “…Due to these data, the strain was subjected to whole genome sequencing to uncover its genomic potential and further improve the understanding of the strain. …”
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  4. 1004

    Genome-wide transcriptome analysis and drug target discovery reveal key genes and pathways in thyroid cancer metastasis by Minjing Zou, Amal Qattan, Monther Al-Alwan, Hazem Ghebeh, Naif Binjumah, Latifa Al-Haj, Khalid S. A. Khabar, Abdulmohsen Altaweel, Falah Almohanna, Abdullah M. Assiri, Abdelilah Aboussekhra, Ali S. Alzahrani, Ali S. Alzahrani, Yufei Shi

    Published 2025-02-01
    “…However, the mechanisms are still poorly understood. MethodsWe performed genome-wide transcriptome analysis comparing gene expression profile of metastatic thyroid cancer cells (Met) with primary tumor cells established from transgenic mouse models of papillary thyroid cancer (PTC), follicular thyroid cancer (FTC), poorly differentiated thyroid cancer (PDTC), and anaplastic thyroid cancer (ATC).ResultsGenes involved in tumor microenvironment (TME), inflammation, and immune escape were significantly overexpressed in Met cells. …”
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    Machine learning methods for predicting essential metabolic genes from Plasmodium falciparum genome-scale metabolic network. by Itunuoluwa Isewon, Stephen Binaansim, Faith Adegoke, Jerry Emmanuel, Jelili Oyelade

    Published 2024-01-01
    “…It assessed various network properties in Plasmodium falciparum, using a Genome-Scale Metabolic Model (iAM_Pf480) from the BiGG database and essentiality data from the Ogee database. …”
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    Comparative genomic study of the Penicillium genus elucidates a diverse pangenome and 15 lateral gene transfer events by Celine Petersen, Trine Sørensen, Mikkel R. Nielsen, Teis E. Sondergaard, Jens L. Sørensen, David A. Fitzpatrick, Jens C. Frisvad, Kåre L. Nielsen

    Published 2023-02-01
    “…The comprehensive characterization of the genomic diversity in the Penicillium genus supersedes single-reference genomes, which do not necessarily capture the entire genetic variation.…”
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    Genomic signatures of habitat isolation and paleo-climate unveil the “island-like” pattern in the glasshouse plant Rheum nobile by Hum Kala Rana, Santosh Kumar Rana, Hang Sun, Dong Luo

    Published 2025-04-01
    “…The Himalaya and the Hengduan Mountains, known for their ‘Sky Islands’ ecosystems, offer a unique opportunity to study genomic differentiation of endemic plants. While there is growing research on the genetic mechanisms underlying the distinctiveness of species in these regions, gaps remain in understanding the specific genomic processes shaping the “island-like” genetic structure of Rheum nobile. …”
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  19. 1019

    Genome skimming provides evidence to accept two new genera (Apiaceae) separated from the Peucedanum s.l. by Bo-Ni Song, Chang-Kun Liu, Chang-Kun Liu, Jiao-Jiao Deng, Wei-Yan Tan, Song-Dong Zhou, Xing-Jin He

    Published 2025-01-01
    “…Therefore, we conducted a comprehensive taxonomic revision of taxa within the polyphyletic Peucedanum s.l. genus in this study.MethodsWe used two molecular datasets (103 plastomes and 43 nrDNA sequences) generated by genome skimming to reconstructed a reliable phylogenetic framework with high support and resolution. …”
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