Multi-Omics on Traditional Medicinal Plant of the Genus <i>Aconitum</i>: Current Progress and Prospect by Ting Wang, Cai Rangji, Wenbin Liu, Jing Ma, Ruichen Zhou, Liang Leng, Yi Zhang

“…The use of high-throughput omics allows for the investigation of <i>Aconitum</i> plant genetics, gene regulation, metabolic pathways, and growth and development. …”
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Transcriptional regulation by CHIP/LDB complexes. by Revital Bronstein, Liron Levkovitz, Nir Yosef, Michaela Yanku, Eytan Ruppin, Roded Sharan, Heiner Westphal, Brian Oliver, Daniel Segal

“…The nuclear adaptor CHIP/LDB is a major developmental regulator capable of forming tissue-specific transcription complexes with various types of transcription factors and cofactors, making it a valuable model to study the intricacies of gene regulation. To date only few CHIP/LDB complexes target genes have been identified, and possible tissue-dependent crosstalk between these complexes has not been rigorously explored. …”
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Transcriptome-wide association study identifies genes associated with bladder cancer risk by Siting Li, Jiang Gui, Margaret R. Karagas, Michael N. Passarelli

“…Abstract Genome-wide association studies (GWAS) have detected several susceptibility variants for urinary bladder cancer, but how gene regulation affects disease development remains unclear. …”
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Discovery of Novel Leaf Rust Responsive microRNAs in Wheat and Prediction of Their Target Genes by Dhananjay Kumar, Dharmendra Singh, Pulkit Kanodia, Kumble Vinod Prabhu, Manish Kumar, Kunal Mukhopadhyay

“…MicroRNAs are endogenous small noncoding RNAs which play critical roles in gene regulation. Few wheat (Triticum aestivum L.) miRNA sequences are available in miRBase repertoire and knowledge of their biological functions related to biotic stress is limited. …”
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The role of the pAbp gene encoding the cytoplasmic poly(A)-binding protein in spermatogenesis of Drosophila melanogaster by E. U. Bolobolova, E. M. Baricheva, N. V. Dorogova

“…In Drosophila spermatogenesis, posttranscriptional mechanisms of gene regulation play an important role, so cytoplasmic PABP can have significant function in this process. …”
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Optogenetic regulation of endogenous gene transcription in mammals by E. S. Omelina, A. V. Pindyurin

“…We also discuss the advantages and disadvantages of these DNA targeting tools in the context of the light-inducible gene regulation systems.…”
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Predicting microRNA target genes using pan-cancer correlation patterns by Shuting Lin, Peng Qiu

“…Together, this analysis revealed a novel framework for uncovering previously unidentified miRNA-gene relationships, enhancing the collective comprehension of miRNA-mediated gene regulation.…”
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The histone methyltransferase DOT1B is dispensable for stage differentiation and macrophage infection of Leishmania mexicana by Nicole Eisenhuth, Elisa Theres Rauh, Melina Mitnacht, Andrea Debus, Ulrike Schleicher, Falk Butter, Katerina Pruzinova, Petr Volf, Christian J. Janzen

“…Conserved histone methyltransferases of the DOT1 family are involved in replication regulation, cell cycle progression, stage differentiation, and gene regulation in trypanosomatids. However, the specific functions of these enzymes depend on the host evasion strategies of the parasites. …”
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Unveiling Tissue‐Specific RNA Landscapes in Mouse Organs During Fasting and Feeding Using Nanopore Direct RNA Sequencing by Chengfei Jiang, Ping Li, Haiming Cao

“…Collectively, this findings reveal previously unrecognized layers of gene regulation, offering new insights into the metabolic basis of organ function.…”
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Methods of massive parallel reporter assays for investigation of enhancers by S. E. Romanov, D. A. Kalashnikova, P. P. Laktionov

“…These approaches have contributed substantially to the understanding of the fundamental principles of gene regulation.…”
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Surprising features of nuclear receptor interaction networks revealed by live-cell single-molecule imaging by Liza Dahal, Thomas GW Graham, Gina M Dailey, Alec Heckert, Robert Tjian, Xavier Darzacq

“…SMT and PAPA thus provide a direct way to probe which components are functionally limiting within a complex TF interaction network providing new insights into mechanisms of gene regulation in vivo with implications for drug development targeting nuclear receptors.…”
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Exploring the protective role of caffeine against Taraxacum-Induced ribotoxic stress mediated through autophagy and mitochondrial depolarization by Chien-Jung Lin, Shu-Ting Liu, Zih-Syuan Wu, Shih-Ming Huang, Teng-Wei Chen

“…By providing detailed information on Taraxacum-induced rRNA cleavage and N-truncated histone H3’s mechanisms of gene regulation, we hope to understand their respective cellular death and survival stresses.…”
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FishPi: a bioinformatic prediction tool to link piRNA and transposable elements by Alice M. Godden, Benjamin Rix, Simone Immler

“…A tool to link piRNAs with complementary TE targets will improve our understanding of the role of piRNAs in genome maintenance and gene regulation. Existing tools such as TEsmall can process sRNA-seq datasets to produce differentially expressed piRNAs, and piRScan developed for nematodes can link piRNAs and TEs but it requires knowledge about the target region of interest and works backwards. …”
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miR-134-3p Regulates Cell Proliferation and Apoptosis by Targeting INHBA via Inhibiting the TGF-β/PI3K/AKT Pathway in Sheep Granulosa Cells by Xinai Huang, Yongjin Bao, Fan Yang, Xiaodan Li, Feng Wang, Chunxiang Zhang

“…Although miRNAs are essential for post-transcriptional gene regulation, it is not yet known how they affect the expression of <i>INHBA</i> during follicle development. …”
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Recent trends in nanocomposite packaging films utilising waste generated biopolymers: Industrial symbiosis and its implication in sustainability by Zeba Tabassum, Anand Mohan, Narsimha Mamidi, Ajit Khosla, Anil Kumar, Pratima R. Solanki, Tabarak Malik, Madhuri Girdhar

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Epigenetic regulation of banana fruit ripening: global and specific DNA methylation profile, and characterization of DNA methylation-related genes by Dina Hermawaty, Mita Azzahra Putri, Sekar Prabhandiya, Fenny Martha Dwivany, Karlia Meitha

“…Additionally, methylation dynamics were observed on CpG islands of two critical transcription factors, MaMADS1 and MaMADS2, though gene regulation was unaffected. The study highlights that DNA methylation regulation precedes visible physiological changes in ripening, offering insights into the molecular mechanisms governing fruit ripening and potential strategies to enhance quality and extend shelf life.…”
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Protein interference for regulation of gene expression in plants by A. O. Vyacheslavova, I. A. Abdeeva, E. S. Piruzian, S. A. Bruskin

“…Transcription factors (TFs) play a central role in the gene regulation associated with a plant's development and its response to the environmental factors. …”
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Emerging roles of circular RNAs on the regulation of production traits in chicken by Guishuang You, Hong Long, Xiaoxu Shen, Huadong Yin, Shibin Zhang

“…This performance is determined by various production traits that are primarily influenced by multiple factors, including epigenetics—a critical aspect of gene regulation. Circular RNAs (circRNAs), a unique class of non-coding RNAs, have emerged as key epigenetic regulators. …”
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The interaction of Adipose Derived Stem Cells and Breast Cancer by Natasha Cunningham, Ava O'Meara, Cathy L. Brougham

“…MicroRNAs have been linked to gene regulation essential in oncogenic, and tumour suppression as well as cell signalling pathways in BC. …”
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Brain-derived tau oligomer polymorphs: distinct aggregations, stability profiles, and biological activities by Filippa Lo Cascio, Suhyeorn Park, Urmi Sengupta, Nicha Puangmalai, Nemil Bhatt, Nikita Shchankin, Cynthia Jerez, Naomi Moreno, Alice Bittar, Rhea Xavier, Yingxin Zhao, Cankun Wang, Hongjun Fu, Qin Ma, Mauro Montalbano, Rakez Kayed

“…Our results indicate that the aBDTOs possess different structural and morphological features that impact neuronal function, gene regulation, and ultimately disease progression. The distinct tau oligomeric polymorphs may thus contribute to the development of clinical phenotypes and shape the progression of diseases. …”
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