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661
An Improved Pearson’s Correlation Proximity-Based Hierarchical Clustering for Mining Biological Association between Genes
Published 2014-01-01“…Microarray gene expression datasets has concerned great awareness among molecular biologist, statisticians, and computer scientists. …”
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662
Treatment of Cancer Gene Changes in Chronic Myeloid Leukemia by Big Data Analysis Platform-Based Dasatinib
Published 2022-01-01“…At the same time, the gene expression profile was analyzed by principal component analysis (PCA) in the analysis system. …”
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663
Messenger RNA Turnover Processes in Escherichia coli, Bacillus subtilis, and Emerging Studies in Staphylococcus aureus
Published 2009-01-01“…We conclude by discussing emerging studies on the role modulating mRNA stability has on gene expression in the important human pathogen Staphylococcus aureus.…”
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664
Shortening of 3'UTRs correlates with poor prognosis in breast and lung cancer.
Published 2012-01-01“…A major part of the post-transcriptional regulation of gene expression is affected by trans-acting elements, such as microRNAs, binding the 3' untraslated region (UTR) of their target mRNAs. …”
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665
Fungal-Host Interaction: Curcumin Modulates Proteolytic Enzyme Activity of Candida albicans and Inflammatory Host Response In Vitro
Published 2018-01-01“…However, proteinase gene expression was not downregulated after curcumin treatment. …”
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666
Autoregulation of the glial gene reversed polarity in Drosophila
Published 2025-01-01“…The upstream 2 kb within the repo CRD has remarkable repo-dependent gene expression activity, and mutagenesis of RBS1 in this 2 kb region results in a significant decrease in repo-induced reporter gene expression in both systems. …”
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667
Neuroprotection Caused by Hyperoxia Preconditioning in Animal Stroke Models
Published 2011-01-01“…Neuroprotection induced by HO exhibits specific adaptation responses that involve a number of cellular and biochemical alterations, including metabolic homeostasis and reprogramming of gene expression. The changes in the metabolic pathways are generally short lived and reversible, while the consequences of gene expression are a long-term process and may lead to the permanent alteration in the pattern of gene expression. …”
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668
Particulate Matter-Induced Acute Coronary Syndrome: MicroRNAs as Microregulators for Inflammatory Factors
Published 2021-01-01“…Various plausible pathogenic mechanisms have been identified, including microRNAs (miRNAs), an epigenetic regulator for gene expression. Endogenous miRNAs, average 22-nucleotide RNAs (ribonucleic acid), regulate gene expression through mRNA cleavage or translation repression and can influence proinflammatory gene expression posttranscriptionally. …”
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669
Meta-analysis of retinal transcriptome profiling studies in animal models of myopia
Published 2025-01-01“…The five studies underwent transcriptome meta-analyses to determine retinal gene expression changes and associated pathways. The results were compared with genes associated with human myopia.ResultsDifferential gene expression analysis of form-deprived mouse retinas revealed 235 significantly altered transcripts, implicating the BMP2 signaling pathway and circadian rhythms, among others. …”
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670
Mono-allelic epigenetic regulation of polycistronic transcription initiation by RNA polymerase II in Trypanosoma brucei
Published 2025-02-01“…Our findings support epigenetic regulation of Pol II transcription initiation as a viable mechanism of gene expression control in T. brucei. This has implications for our understanding how trypanosomes utilize polycistronic genome organization to regulate gene expression during its life cycle.…”
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671
Molecular Imaging of Gliomas
Published 2002-10-01“…Noninvasive imaging of endogenous gene expression by means of positron emission tomography (PET) may reveal insight into the molecular basis of pathogenesis and metabolic activity of the glioma and the extent of treatment response. …”
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672
Hematological profile and its correlation with reverse transcription–polymerase chain reaction-based serial quantitative detection of BCR-ABL in chronic myeloid leukemia patients a...
Published 2024-12-01“…The eosinophil count was raised. The BCR-ABL gene expression was positively and significantly correlated with total count. …”
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673
Protective effects of resveratrol on the expression of catalase, glutathione peroxidase, and superoxide dismutase genes in the ovary and their activity in the serum of rats exposed...
Published 2025-01-01“…Results: Lead acetate significantly downregulates Cat, Gpx, and Sod gene expression, but Res significantly upregulates gene expression, especially at doses of 40 mg/kg for Cat, 20 mg/kg and 40 mg/kg for Gpx, and 80 mg/kg for Sod. …”
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674
Intratumor Genetic Heterogeneity of Breast Carcinomas as Determined by Fine Needle Aspiration and TaqMan Low Density Array
Published 2007-01-01“…Background: Gene expression profiling is thought to be an important tool in determining treatment strategies for breast cancer patients. …”
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675
Novel Treatment of Small-Cell Neuroendocrine of the Vagina
Published 2018-01-01“…Eighty-five percent of patients die within one year of diagnosis from metastatic disease despite multimodal therapy. Gene expression profiling of tumor tissue may be useful for treatment options for various malignancies. …”
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676
Anti-correlation of LacI association and dissociation rates observed in living cells
Published 2025-01-01“…Using a stochastic model of the relationship between gene expression variability and binding kinetics, we performed single-cell gene expression measurements to infer association and dissociation rates for a set of 35 different LacI binding sites. …”
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677
TRPV Subfamily (TRPV2, TRPV3, TRPV4, TRPV5, and TRPV6) Gene and Protein Expression in Patients with Ulcerative Colitis
Published 2020-01-01“…TRPV3 gene expression was significantly higher in controls than in active UC patients (P=0.002). …”
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678
T Cell Activation and Regulation of HIV-1: Same Effectors with Distinct Outcomes
Published 1999-01-01“…The molecular mechanisms that regulate the function of the immune system and human immunodeficiency virus type-1 (HIV-1) gene expression are diverse and complicated. However, replication of HIV-1 is controlled by many of the same regulatory signals that play a crucial role in the transcriptional regulation of the immune system. …”
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679
Role of tRNA-Derived Fragments in Protozoan Parasite Biology
Published 2025-01-01“…Furthermore, we investigate how these tsRNAs either modulate gene expression within the parasite itself or are packaged into extracellular vesicles to alter host gene expression, thereby promoting parasite survival and adaptation.…”
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680
Synergetic role of TRPV4 inhibitor and mechanical loading on reducing inflammation
Published 2025-01-01“…Gene expression analysis further demonstrated significant reductions in pro-inflammatory gene expression and a synergistic promotion of anti-inflammatory phenotypes under TRPV4 inhibition at 6% mechanical strain. …”
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