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            2641
Identification of iron metabolism-related genes in coronary heart disease and construction of a diagnostic model
Published 2024-11-01“…BackgroundCoronary heart disease is a common cardiovascular disease, yferroptosiset its relationship with iron metabolism remains unclear.MethodsGene expression data from peripheral blood samples of patients with coronary heart disease and a healthy control group were utilized for a comprehensive analysis that included differential expression analysis, weighted gene co-expression network analysis, gene enrichment analysis, and the development of a logistic regression model to investigate the associations and differences between the groups. …”
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            2642
The role of acetylation and deacetylation in cancer metabolism
Published 2025-01-01“…They modulate the activity of transcription factors that drive gene expression changes. Metabolic enzymes are also affected, altering cellular metabolism to support tumour growth.…”
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            2643
The interplay between epitranscriptomic RNA modifications and neurodegenerative disorders: Mechanistic insights and potential therapeutic strategies
Published 2024-12-01“…These epitranscriptomic changes intricately control gene expression, influencing cellular functions and contributing to disease pathology. …”
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            2644
Research Progress of Single-Cell Transcriptome Sequencing Technology in Plants
Published 2024-10-01“…Single-cell transcriptome sequencing (scRNA-seq) technology can be used to determine the gene expression levels of each individual cell, facilitating the study of intercellular expression heterogeneity. …”
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            2645
Combatting biofilm-mediated infections in clinical settings by targeting quorum sensing
Published 2024-12-01“…Quorum sensing (QS) is a process of cell-to-cell communication that bacteria use to coordinate gene expression in response to cell density, which is crucial for biofilm formation and maintenance.. …”
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            2646
The RNA-dependent association of phosphatidylinositol 4,5-bisphosphate with intrinsically disordered proteins contribute to nuclear compartmentalization.
Published 2024-12-01“…This suggests the pivotal role of PIP2 in the establishment of a functional nuclear architecture competent for gene expression.…”
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            2647
Mining contextually meaningful subgraphs from a vertex-attributed graph
Published 2024-11-01“…Integrative analysis of interaction networks with gene expression and annotations enables the discovery of context-specific complexes and improves the identification of functional modules and pathways. …”
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            2648
From barcodes to genomes: a new era of molecular exploration in bryophyte research
Published 2025-01-01“…Recent research involving plastomes, mitogenomes, and transcriptomes of various bryophyte species has provided insights into molecular changes and gene expression in response to environmental stressors. …”
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            2649
Fatty acid amides present in Camembert cheese improved cognitive decline after oral administration in mice
Published 2024-08-01“…Moreover, we investigated changes in gene expression related to neurogenesis in the hippocampus. …”
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            2650
Epigenetics and Breast Cancers
Published 2012-01-01“…Other enzymes are recruited to the region by ligand-ERα dimers which activate DNA demethylases to act simultaneously to increase gene expression of protooncogenes and growth-promoting genes. …”
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            2651
Effect of Caloric Restriction on Hepatic Sinusoidal System and Stellate Cells in Mice
Published 2014-01-01“…Caloric restriction reduced collagen deposits in liver sections and lowered the gene expression of α1-(I) collagen but not α-smooth muscle actin. …”
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            2652
Polyomavirus large T antigens: Unraveling a complex interactome
Published 2025-06-01“…All members of the polyomavirus family encode a large T antigen (LT) protein that plays essential roles in viral DNA replication, regulation of viral gene expression, and the manipulation of numerous cellular pathways. …”
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            2653
Identification of the Immune Cell Infiltration Landscape in Head and Neck Squamous Cell Carcinoma (HNSC) for the Exploration of Immunotherapy and Prognosis
Published 2022-01-01“…An analysis of the Cancer Genome Atlas (TCGA) database revealed gene expression profiles and corresponding clinical information. …”
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            2654
GENETIC PATHWAYS LEADING TO THERAPY-RELATED MYELOID NEOPLASMS
Published 2011-01-01“…<span> </span>Cytogenetic analysis, molecular analysis and gene expression profiling analysis of t-MN has revealed that there are distinct subtypes of the disease; however, our understanding of the genetic basis of t-MN is incomplete.…”
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            2655
A novel statistical framework for meta-analysis of total mediation effect with high-dimensional omics mediators in large-scale genomic consortia.
Published 2024-11-01“…We applied the developed method to 5 TOPMed studies with over 5800 participants to estimate the mediation effects of gene expression on age-related variation in systolic blood pressure and sex-related variation in high-density lipoprotein (HDL) cholesterol. …”
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            2656
Circulating microRNA as promising biomarkers in hypertrophic cardiomyopathy: can advanced cardiac magnetic resonance unlock new insights in research?
Published 2024-12-01“…Non-coding RNAs, particularly microRNAs, have emerged as promising biomarkers due to their role in regulating gene expression in both healthy and pathological hearts. …”
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            2657
ROLE OF THE MODULATORY MEDIATOR SEROTONIN IN THE INDUCTION OF EPIGENETIC PROCESSES DURING LONG TERM MEMORY FORMATION IN HELIX
Published 2015-01-01“…They include posttraslational histone modifications, which lead to chromatin remodeling and thereby influences gene expression involved in learning. Mollusks are a popular model in neurobiology, because they have relatively simple CNSs with giant neurons. …”
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            2658
Functions and applications of RNA interference and small regulatory RNAs
Published 2024-11-01“…This process involves Argonaute/small RNA (AGO/sRNA) complexes that target transcripts via sequence complementarity and modulate gene expression and epigenetic modifications. RNAi is a highly conserved gene regulatory phenomenon that recognizes self- and non-self nucleic acids, thereby defending against invasive sequences. …”
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            2659
Evaluation of 2′-Deoxy-2′-Flouro-5-Methyl-1-β--Arabinofuranosyluracil as a Potential Gene Imaging Agent for Expression In Vivo
Published 2002-04-01“…2′-Deoxy-2′-flouro-5-methyl-1-β- d -arabinofuranosyluracil (FMAU) has been evaluated in HT-29 cells as a potential positron emission tomography (PET) radiotracer for imaging HSV-tk gene expression in vivo. In vitro experiments demonstrate that the accumulation of [ 14 C]-FMAU in HSV-tk -expressing cells is 2.4-fold ( p < .02), 4.0-fold ( p < .001), and 5.3-fold ( p < .001) higher than the wild-type cells at 1, 3, and 5 hr, respectively. …”
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            2660
Metabolome and transcriptomics analyses reveal quality differences between Camellia tachangensis F. C. Zhang and C. sinensis (L.) O. Kunzte.
Published 2024-01-01“…We analyzed changes in metabolite abundance and gene expression patterns of C. tachangensis and C. sinensis using metabonomics and transcriptomics. …”
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