Serological Profile of Anti-<i>Toxoplasma gondii</i> Antibodies in Liver Transplant Recipients by Gabriella Beltrame Pintos, Francielly Camilla Bazílio Laurindo Pires, Nathália Zini, Rita Cássia Martins Alves da Silva, Francisco Inaldo Mendes Silva Junior, Renato Ferreira da Silva, Tainara Souza Pinho, Luiz Carlos de Mattos, Cinara Cássia Brandão

“…Hepatosplenomegaly (47.9%), fever (35.4%), encephalopathy (20.8%), and headache (16.7%) were commonly observed symptoms. …”
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Application of gastrointestinal decompression method in determining tip position of the triple-lumen nasointestinal tube in critically ill patients (胃肠减压法在危重症患者三腔鼻肠管位置判断中的应用)... by WANG Zhimin (王志民), LI Xuejing (李雪晶), QIAO Shouang (乔首昂)

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Rapid spread of the SARS-CoV-2 Omicron XDR lineage derived from recombination between XBB and BA.2.86 subvariants circulating in Brazil in late 2023 by Ighor Arantes, Kimihito Ito, Marcelo Gomes, Felipe Cotrim de Carvalho, Walquiria Aparecida Ferreira de Almeida, Ricardo Khouri, Fabio Miyajima, Gabriel Luz Wallau, Felipe Gomes Naveca, Elisa Cavalcante Pereira, Marilda Mendonça Siqueira, Paola Cristina Resende, Gonzalo Bello

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Virological Aspects of COVID-19 in Patients with Hematological Malignancies: Duration of Viral Shedding and Genetic Analysis by Asma Themlaoui, Massimo Ancora, Kais Ghedira, Yosra Mhalla, Manel Hamdoun, Maroua Bahri, Lamia Aissaoui, Raihane Ben Lakhal, Adriano Di Pasquale, Cesare Camma, Olfa Bahri

“…SARS-CoV-2 infection was symptomatic in 48.6% of cases with fever, and cough was symptomatic in 61% of cases; the mortality rate was estimated to be 13.5%. …”
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Intratumoral oncolytic virus OH2 injection in patients with locally advanced or metastatic sarcoma: a phase 1/2 trial by Lu Zhang, Shu Li, Jing Huang, Yan Wu, Liang Han, Tian Gao, Qingxia Fan, Suxia Luo, Binlei Liu, Lixin Zhou, Xinyu Wang, Ling Jia, Jianhua Shi, Zhichao Tan, Zhengfu Fan, Sijuan Ding, Chujie Bai, Ruifeng Xue, Jiayong Liu

“…The most frequent treatment-related adverse events (TRAEs) were fever (n=9). Grade 3 or 4 TRAEs were reported in four patients (15.4%). …”
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Detection of viral antigen and inflammatory mediators in fatal pediatric dengue: a study on lung immunopathogenesis by Leandro Junqueira Moragas, Laíza Vianna Arruda, Laíza Vianna Arruda, Lucca de Lima Siqueira Oliveira, Felipe de Andrade Vieira Alves, Felipe de Andrade Vieira Alves, Natália Gedeão Salomão, Natália Gedeão Salomão, Jemima Fuentes Ribeiro da Silva, Carlos Alberto Basílio-de-Oliveira, Rodrigo Panno Basílio-de-Oliveira, Ronaldo Mohana-Borges, Caio Gonçalves Azevedo, Gabriela Xavier de Oliveira, Jorge José de Carvalho, Fernando Colonna Rosman, Fernando Colonna Rosman, Marciano Viana Paes, Kíssila Rabelo, Kíssila Rabelo

“…IntroductionThe dengue virus (DENV) is the etiological agent that causes dengue fever illness, an arbovirus with a major endemic potential that has become increasingly prevalent in Brazil and has already been associated with fatal cases in children. …”
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Pediatric bacterial meningitis in southern China: analysis of 838 cases by Lianfeng Chen, Wen-Lin Wu, Yuanyuan Gao, Xiaojing Li, Sida Yang, Huici Liang, Kelu Zheng, Yani Zhang, Haixia Zhu, Yang Tian, Bingwei Peng, Haisheng Lin, Xiuying Wang, Shuyao Ning, Yinyan Gan, Chi Hou, Yinting Liao, Huiling Sheng, Wen-Xiong Chen, Wen-Xiong Chen

“…Common symptoms included fever, seizure, lethargy, vomiting, anorexia, poor feeding, and irritability. …”
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Understanding limb necrotizing infections: A comprehensive approach by A. Garrido-Hidalgo, J. García-Coiradas, M. Echevarría-Marín, S. Llanos, J.A. Valle-Cruz, F. Marco

“…All reported severe treatment-resistant pain; sixteen had fever exceeding 37.8 °C (72.7%). Skin lesions occurred in twelve (54.5%), and thirteen had hypotension and tachycardia (59.1%).Treatment involved resuscitative support, antibiotherapy, and radical debridement. …”
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[Artículo traducido] Infecciones necrosantes de partes blandas: aproximación diagnóstico-terapéutica by A. Garrido-Hidalgo, J. García-Coiradas, M. Echevarría-Marín, S. Llanos, J.A. Valle-Cruz, F. Marco

“…All reported severe treatment-resistant pain; sixteen had fever exceeding 37.8 °C (72.7%). Skin lesions occurred in twelve (54.5%), and thirteen had hypotension and tachycardia (59.1%). …”
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A lineage 1 branch porcine reproductive and respiratory syndrome virus live vaccine candidate provides broad cross-protection against HP-like PRRSV in piglets by Chao Li, Jinhao Li, Bangjun Gong, Hu Xu, Zhenyang Guo, Lirun Xiang, Siyu Zhang, Qi Sun, Jing Zhao, Menglin Zhang, Yan-Dong Tang, Chaoliang Leng, Jianan Wu, Qian Wang, Jinmei Peng, Guohui Zhou, Huairan Liu, Tongqing An, Xuehui Cai, Zhi-Jun Tian, Hongliang Zhang

“…The results revealed that piglets challenged with DLF presented clinical symptoms such as continuous high fever and an obvious decrease in daily weight gain. …”
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Comprehensive analysis of endoscopic ultrasound (EUS) in mediastinal lesions: patient characteristics, diagnostic outcomes, safety, and efficacy: a multi-country study by Hussein Okasha, Eyad Gadour, Ghias Un Nabi Tayyab, Andrada Seicean, Elbacha Hicham, Emad Emad, Turki Alamri, Nadeem Tehami, Heero Ismael Faraj, Ahmed Alzamzamy, Hiwa Hussein, Mohammed Tag-Adeen, Mohamed Elbasiony, Abed Al-Lehibi, Shereen Saleh, Zaher Houmani, Mohamed Abdelghani, Khaled Ragab, Zahi Ismaili, Othmane Drir, Elsayed Ghoneem, Omar Abdallah, Souad Rebiai, Nonthalee Pausawasdi, Fedoua Rouibaa, Mohamed Borahma, Hassan Atalla, Mahmoud Farouk, Ahmed Altonbary

“…EUS-FNB accounted for a 0.5% complication incidence rate each for fever, pain, thoracic pain, and hemorrhage. EUS-FNA had no complication rate. …”
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Evaluation of dried blood spot sampling for real-time PCR malaria diagnostics in a rural setting in Angola by Alejandro Mediavilla, Begoña Febrer-Sendra, Aroa Silgado, Patricia Martínez-Vallejo, Beatriz Crego-Vicente, Arlette Nindia, Carles Rubio Maturana, Lidia Goterris, Joan Martínez-Campreciós, Sandra Aixut, Pedro Fernández-Soto, María Luisa Aznar, Antonio Muro, Inés Oliveira-Souto, Israel Molina, Elena Sulleiro

“…Samples from both phases of the study were analyzed by generic real-time PCR (Plasmodium spp.) and the subsequent positive samples underwent species-specific real-time PCR (Plasmodium species) and (ii) cross-sectional study conducted at the Hospital Nossa Senhora da Paz, Cubal (Angola), including 200 participants with fever. For each patient, a fresh capillary blood specimen [for thin and thick blood films and rapid diagnostic test (RDT)] and venous blood, collected as DBSs (two 10-µl circles were combined for a total volume of 20 µl of DBS), were obtained. …”
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Phase I study of intratumoral administration of CV8102 in patients with advanced melanoma, squamous cell carcinoma of the skin, squamous cell carcinoma of the head and neck, or ade... by Lucie Heinzerling, Michael Fluck, Caroline Robert, Celeste Lebbe, Erika Richtig, Sven D Koch, Ulrike Gnad-Vogt, Tobias Seibel, Thomas Eigentler, Juan Martin-Liberal, Sebastian Ochsenreither, Peter Mohr, Patrick Terheyden, Carsten Weishaupt, Michael Erdmann, Lukas Koch, Ainara Soria, Igor Samoylenko, Jürgen Krauß, Peter Brossart, Franz Georg Bauernfeind, Marina Gonzalez, Peter Wengenmayer, Ioannis Thomas, Artem Poltoratskiy, Marina Sekacheva, Beate Schmitt-Bormann, Gianluca Quintini, Martin Falk, Paula Codó, Arjun Oberoi, Jana Hess, Yulia Semiletova, Casilda Llacer Perez, Oliver Schönborn-Kellenberger

“…Common treatment-emergent adverse events were fever (57%), chills (37%) and fatigue (25%). In the dose escalation part, objective responses occurred in 3/33 patients treated with CV8102 as monotherapy and in 2/25 patients treated with CV8102 plus a PD-1 inhibitor. …”
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Dysregulated autoantibodies targeting AGTR1 are associated with the accumulation of COVID-19 symptoms by Dennyson Leandro M. Fonseca, Maj Jäpel, Michael Adu Gyamfi, Igor Salerno Filgueiras, Gabriela Crispim Baiochi, Yuri Ostrinski, Gilad Halpert, Yael Bublil Lavi, Elroy Vojdani, Thayna Silva-Sousa, Júlia Nakanishi Usuda, Juan Carlo Santos e Silva, Paula P. Freire, Adriel Leal Nóbile, Anny Silva Adri, Pedro Marçal Barcelos, Yohan Lucas Gonçalves Corrêa, Fernando Yuri Nery do Vale, Letícia Oliveira Lopes, Solveig Lea Schmidt, Xiaoqing Wang, Carl Vahldieck, Benedikt Fels, Lena F. Schimke, Gustavo Cabral-Miranda, Mario Hiroyuki Hirata, Taj Ali AKhan, Yen-Rei A. Yu, Rodrigo JS Dalmolin, Howard Amital, Aristo Vojdani, Haroldo Dutra Dias, Helder Nakaya, Hans D. Ochs, Jonathan I. Silverberg, Jason Zimmerman, Israel Zyskind, Avi Z. Rosenberg, Kai Schulze-Forster, Harald Heidecke, Rusan Catar, Guido Moll, Alexander Hackel, Kristina Kusche-Vihrog, Yehuda Shoenfeld, Gabriela Riemekasten, Reza Akbarzadeh, Alexandre H. C. Marques, Otavio Cabral-Marques

“…Significant correlations were identified between specific AABs and symptoms such as fever, muscle aches, anosmia, and dysgeusia. Notably, anti-AGTR1 antibodies, which contribute to endothelial glycocalyx (eGC) degradation, a process reversed by losartan, have emerged as strong predictors of core symptoms. …”
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COVID-19 Vaccines Effectiveness and Safety in Trinidad and Tobago: A Systematic Review and Meta-Analysis by Angel Justiz-Vaillant, Kimberly Roopnarine, Shaundell Solomon, Alyssa Phillips, Solange Sandy, Alyssa Subero, Sarah Seepersad, Nicholas Span, Phalmanie Ramnath, Akaasha Ramnarine, Bimala Ramdath, Chelsea Rampaul, Renissa Ramdial, Dana Phagoo, Thalia Ramdhanie, Vinaya Moonilal, Emily-Marie Poliah, Steffan Poonwassie, Karishta Punilal, Sarah Panchoo, Justice Parris, Steven Oudit, Trudy Muir, Johnson Nicholas-Joseph, Bijey Raj Pandit, Sanjeev Pakeerah, Vesham Sookoo, Patrice Richards, Tishia John, Darren Gopaul, Sachin Soodeen, Odette Arozarena-Barbosa, Arlene Williams, Chandrashehkar Unakal, Rodolfo Arozarena Fundora, Reinand Thompson, Patrick Eberechi Akpaka

“…The Pfizer-BioNTech and Moderna vaccines demonstrated the highest efficacy, particularly against COVID-19 variants, while Janssen and Sinopharm were comparatively less effective. mRNA vaccines, such as Pfizer-BioNTech and Oxford-AstraZeneca, were associated with more frequent and severe side effects, including soreness, fever, and cardiovascular issues. The review also identified significant gaps in the current scientific literature regarding COVID-19 vaccination issues in Trinidad and Tobago. …”
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Higher frequency of interstate over international transmission chains of SARS-CoV-2 virus at the Rio Grande do Sul - Brazil state borders by Filipe Zimmer Dezordi, José Valter Joaquim Silva Júnior, Terimar Facin Ruoso, Angela Giovana Batista, Pedro Mesquita Fonseca, Larissa Paim Bernardo, Richard Steiner Salvato, Tatiana Schäffer Gregianini, Thaísa Regina Rocha Lopes, Eduardo Furtado Flores, Rudi Weiblen, Patrícia Chaves Brites, Mônica de Medeiros Silva, João Batista Teixeira da Rocha, Gustavo de Lima Barbosa, Lais Ceschini Machado, Alexandre Freitas da Silva, Marcelo Henrique Santos Paiva, Matheus Filgueira Bezerra, Tulio de Lima Campos, Tiago Gräf, Daniel Angelo Sganzerla Graichen, Elgion Lucio da Silva Loreto, Gabriel da Luz Wallau

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Viral diversity in wild rodents in the regions of Canaã de Carajás and Curionopólis, State of Pará, Brazil by Adriana Freitas Moraes Monteiro, Adriana Freitas Moraes Monteiro, Fábio Silva da Silva, Ana Cecília Ribeiro Cruz, Ana Cecília Ribeiro Cruz, Sandro Patroca da Silva, Alice Louize Nunes Queiroz, Livia Medeiros Neves Casseb, Livia Medeiros Neves Casseb, Livia Carício Martins, Livia Carício Martins, Daniele Barbosa de Almeida Medeiros, Daniele Barbosa de Almeida Medeiros

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Listeria monocytogenes Meningoencephalitis and Cerebral Abscess in a Heart Transplant Recipient by Paul C. Adjei

“…A 54-year-old male, five months postorthotopic heart transplantation, presented with intermittent fevers, headaches, and “soupy” stools. Prior to presentation, he had low-level cytomegalovirus (CMV) viremia for two straight weeks. …”
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Fatal Fulminant Hepatic Failure from Adenovirus in Allogeneic Bone Marrow Transplant Patients by Jatin M. Vyas, Wayne A. Marasco

“…Both patients presented with high fevers, abnormal liver functions tests, and hypodense lesions in the liver by CT scan. …”
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Klebsiella pneumoniae Renal Abscess Syndrome: A Rare Case with Metastatic Involvement of Lungs, Eye, and Brain by Divyanshu Dubey, Fayez S. Raza, Anshudha Sawhney, Ambarish Pandey

“…We describe a rare case of Klebsiella pneumoniae renal abscess with metastatic spread leading to endopthalmitis, pulmonary cavitary lesions, and cerebral emboli in a 41-year-old Hispanic female with diabetes mellitus who presented with a four-to-five-day history of fevers, headache, eye pain, and vomiting. She was treated with IV antibiotics and made a gradual but full recovery.…”
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