Flavor Metabolic Pathways of Fermented Large Yellow Croaker with Pediococcus pentosaceus by QIN Fei, ZHANG Shuyu, WEI Haocheng, NI Hui

Subjects: “…large yellow croaker; pediococcus pentosaceus; volatile flavor compounds; key odor-active compounds; free fatty acid; metabolic pathway…”
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CD36 inhibition enhances the anti-proliferative effects of PI3K inhibitors in PTEN-loss anti-HER2 resistant breast cancer cells by You-Yu Liu, Wei-Lun Huang, Sin-Tian Wang, Hui-Ping Hsu, Tzu-Ching Kao, Wei-Pang Chung, Kung-Chia Young

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Polystyrene nanoplastics promote colitis-associated cancer by disrupting lipid metabolism and inducing DNA damage by Shan Tian, Ruixue Li, Jiao Li, Jinhui Zou

“…Inhibition of fatty acid metabolism is a therapeutic target for controlling PS-NP-induced CAC. …”
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Maternal obesity increases hypothalamic miR-505-5p expression in mouse offspring leading to altered fatty acid sensing and increased intake of high-fat food. by Laura Dearden, Isadora C Furigo, Lucas C Pantaleão, L W P Wong, Denise S Fernandez-Twinn, Juliana de Almeida-Faria, Katherine A Kentistou, Maria V Carreira, Guillaume Bidault, Antonio Vidal-Puig, Ken K Ong, John R B Perry, Jose Donato, Susan E Ozanne

“…We demonstrate that targets of miR-505-5p are enriched in fatty acid metabolism pathways and overexpression of miR-505-5p decreased neuronal fatty acid metabolism in vitro. miR-505-5p targets are associated with increased BMI in human genetic studies. …”
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Reveal the pharmacodynamic substances and mechanism of an edible medicinal plant Rhodiola crenulate in DSS-induced colitis through plasma pharmacochemistry and metabolomics by Yu Peng, Xiaoao Xiao, Tingting Ji, Xinyuan Wang, Yixuan Xu, Jianbo Xiao, Hui Cao, Zhiyong Chen, Huifan Liu, Yuanqing Gao, Hongxun Tao

“…Correspondingly, RCE could prevent colitis by improving fatty acid metabolism and secondary bile acid metabolism.…”
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Global Gene Expression Profiling in PPAR-γ Agonist-Treated Kidneys in an Orthologous Rat Model of Human Autosomal Recessive Polycystic Kidney Disease by Daisuke Yoshihara, Masanori Kugita, Tamio Yamaguchi, Harold M. Aukema, Hiroki Kurahashi, Miwa Morita, Yoshiyuki Hiki, James P. Calvet, Darren P. Wallace, Takafumi Toyohara, Takaaki Abe, Shizuko Nagao

“…Stearoyl-coenzyme A desaturase 1 is a key enzyme in fatty acid metabolism found in the top 5 genes downregulated by PIO treatment. …”
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Distinct dynamic regulation of pectoralis muscle metabolomics by insulin and the promotion of glucose-lipid metabolism with extended duration by Xiangli Zhang, Pengfei Du, Ziyang Wang, Yao Zhu, Xuemeng Si, Wen Chen, Yanqun Huang

“…Extended insulin monitoring promotes glucose uptake and glycolysis, alongside enhanced fatty acid metabolism. This research provides insights into the potential mechanisms of insulin action in chicken muscles.…”
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Deficiency of the mitochondrial transporter SLC25A47 minimally impacts hepatic lipid metabolism in fasted and diet-induced obese mice by Brecht Attema, Montserrat A. de la Rosa Rodriguez, Evert M. van Schothorst, Sander Grefte, Guido JEJ. Hooiveld, Sander Kersten

“…Conclusion: Collectively, our results hint at a role of SLC25A47 in amino acid and fatty acid metabolism, yet suggest that SLC25A47 is dispensable for hepatic lipid homeostasis during fasting and high-fat feeding.…”
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Identification of fatty acid anabolism patterns to predict prognosis and immunotherapy response in gastric cancer by Weijie Sun, Yanhong Xia, Feifan Jin, Jinghao Cao, Gaoping Wu, Keyi Li, Yanhua Yu, Yunyi Wu, Gaoqi Ye, Ke Xu, Dengpan Liu, Weidong Jin

“…However, the correlation between fatty acid metabolism and the development and progression of GC remains largely unknown. …”
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Review of the Structural and Dynamic Mechanisms of PPARγ Partial Agonism by Alice J. Kroker, John B. Bruning

“…PPARγ (peroxisome proliferator activated receptor γ) is a ligand activated transcription factor of the nuclear receptor superfamily that controls the expression of a variety of genes involved in fatty acid metabolism, adipogenesis, and insulin sensitivity. …”
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Identification of a transcription factor AoMsn2 of the Hog1 signaling pathway contributes to fungal growth, development and pathogenicity in Arthrobotrys oligospora by Qianqian Liu, Kexin Jiang, Shipeng Duan, Na Zhao, Yanmei Shen, Lirong Zhu, Ke-Qin Zhang, Jinkui Yang

“…Phenotypic and transcriptomic analyses revealed that AoMsn2 is essential for fatty acid metabolism and autophagic pathways. Additionally, untargeted metabolomic analysis identified an important function of AoMsn2 in the modulation of secondary metabolites. …”
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The Metabolic Features of Tumor-Associated Macrophages: Opportunities for Immunotherapy? by Sonja S. Mojsilovic, Slavko Mojsilovic, Victor H. Villar, Juan F. Santibanez

“…Here, we review the main functional TAM metabolic patterns influenced by TME, including glycolysis, amino acid, and fatty acid metabolism. Moreover, this review discusses antitumor immunotherapies that affect TAM functionality by inducing cell repolarizing and metabolic profiles towards an antitumoral phenotype. …”
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Alteration of Energy Substrates and ROS Production in Diabetic Cardiomyopathy by O. Lorenzo, E. Ramírez, B. Picatoste, J. Egido, J. Tuñón

“…Glycolytic enzymes and transporters are impaired by fatty acid metabolism, leading to accumulation of glucose derivatives. …”
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Identification of serum biomarkers for cystic echinococcosis in sheep through untargeted metabolomic analysis using LC–MS/MS technology by Xiao-Xia Wu, Wan-Li Ban, Li-Jiang Wu, Wen-Jing Qi, Mehdi Borhani, Xiao-Ying He, Xiao-Lei Liu, Ming-Yuan Liu, Jing Ding

“…These differential metabolites are involved in various metabolic pathways, including amino acid metabolites (arginine, l-isoleucine, l-valine) and fatty acid metabolism (fenugreek, arachidonic acid, linolenic acid). …”
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Identification of hub genes and pathogenesis in Kawasaki disease based on bioinformatics analysis by Min Cao, Zhenhu Zhang, Qian Liu, Yuda Zhang

“…Results: In this study, 32 Co-DEGs were identified, and these genes mainly participated in neutrophil degranulation, neutrophil activation involved in immune response, and negative regulation of cytokine production involved in immune response; meanwhile, they were primarily enriched in starch and sucrose metabolism, fatty acid metabolism, autophagy and apoptosis, ferroptosis, and other pathways. …”
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Neonatal necrotizing enterocolitis complicated by glutaric acidemia type II: a case report by Yuli Zhang, Yuli Zhang, Longfei Chen, Miao Duan

“…Glutaric acidemia type II (GAII) is an autosomal recessive genetic metabolic disorder associated with mitochondrial dysfunction, characterized by multiple acyl-CoA dehydrogenase deficiency that affects fatty acid metabolism. Necrotizing enterocolitis (NEC) represents a severe inflammatory condition affecting premature neonates. …”
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Cytochrome P450 monooxygenase-mediated eicosanoid pathway: A potential mechanistic linkage between dietary fatty acid consumption and colon cancer risk by Weicang Wang, Jianan Zhang, Guodong Zhang

“…In this review, we will discuss recent studies about the roles of cytochrome P450 monooxygenases in fatty acid metabolism and its roles in colonic inflammation and colon cancer, and how this information could help us to clarify the health impacts of dietary fatty acids. …”
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Accumulation of Oxidized Low-Density Lipoprotein in Psoriatic Skin and Changes of Plasma Lipid Levels in Psoriatic Patients by Nilgun Solak Tekin, Ishak Ozel Tekin, Figen Barut, Emine Yilmaz Sipahi

“…Abnormalities in essential fatty acid metabolism, free radical generation, lipid peroxidation, and release of lymphokines have been proposed. …”
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Quantitative Proteomic Analysis of Hepatic Tissue of T2DM Rhesus Macaque by Tingfu Du, Shuaiyao Lu, Qinfang Jiang, Yun Li, Kaili Ma

“…Pathway analyses indicated that the biological functions of differentially expressed proteins were related to glycolysis/gluconeogenesis, fatty acid metabolism, complements, and coagulation cascades. …”
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Relationship between Fecal Content of Fatty Acids and Cyclooxygenase mRNA Expression and Fatty Acid Composition in Duodenal Biopsies, Serum Lipoproteins, and Dietary Fat in Colecto... by K. Almendingen, A. T. Høstmark, L. N. Larsen, O. Fausa, J. Bratlie, L. Aabakken

“…Future studies should focus on molecular mechanisms relevant to fatty acid metabolism, inflammation, and angiogenesis, in addition to nutrition.…”
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