Candidate antirheumatic genotherapeutic plasmid constructions have low immunogenicity by T. S. Nepomnyashchikh, T. V. Tregubchak, S. N. Yakubitskiy, O. S. Taranov, R. A. Maksyutov, S. N. Shchelkunov

“…Poxviruses, as compared to other viral families, have an unprecedentedly rich set of such immunomodulatory genes. …”
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Transcriptomics Analysis of Maize (<i>Zea mays</i> L.) in Response to the Infection by <i>Setosphaeria turcica</i> by Hui Jia, Pan Li, Bu Tao, Yuwei Liu, Zhihang Liu, Mengfang Zhu, He Zhou, Maocun Wang, Jingao Dong, Shouqin Gu, Xiaodong Gong

“…Moreover, the genes belonging to the NAC, MYB-related, HB, and WRKY transcription factor families were also significantly enriched among the DEGs. …”
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Relationship of Serum Uric Acid Level with Demographic Features, Risk Factors, Severity, Prognosis, Serum Levels of Vitamin D, Calcium, and Magnesium in Stroke by Payam Saadat, Alijan Ahmadi Ahangar, Mansor Babaei, Mandana Kalantar, Mohammad Ali Bayani, Hiva Barzegar, Hemmat Gholinia, Farbod Zahedi Tajrishi, Sekineh Faraji, Fatemeh Frajzadeh

“…A large financial burden is imposed on the families and health systems of countries in addition to the problems related to the disabilities caused by the disease for the patients. …”
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Cytotoxic Activity of Bisphosphonic Derivatives Obtained by the Michaelis–Arbuzov or the Pudovik Reaction by Zsuzsanna Szalai, Janka Bednárik, Boldizsár Szigfrid Tóth, Angéla Takács, Szilárd Tekula, László Kőhidai, Konstantin Karaghiosoff, László Drahos, György Keglevich

“…<b>Conclusions:</b> The new families of compounds synthesized by our novel approaches may be of practical importance due to the significant cytotoxic activity on the cell cultures investigated. …”
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Ecological-based insights into bat populations in the Yucatán Peninsula under a One Health approach: coexistence or biophobia by Ma. Fernanda Sánchez-Soto, Osiris Gaona, Ricardo Mercado-Juárez, Ricardo Mercado-Juárez, Alfredo Yanez-Montalvo, Arit de León-Lorenzana, Gabriela Borja-Martínez, Gabriela Borja-Martínez, Daniela Zaldívar, Stephany Rodríguez-González, Erika N. Hernández-Villegas, Andres Moreira-Soto, Jan Felix Drexler, Gerardo Suzán, Ella Vázquez-Domínguez, Luisa I. Falcón

“…Gut microbiome was mainly composed of Pseudomonadota, Bacillota and Actinobacterota (&gt;90%), and abundant bacterial families included Enterobacteriaceae, Staphylococcaceae and Streptococcaceae. …”
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Infections with Giardia duodenalis and Entamoeba histolytica/Entamoeba dispar as Hidden and Prevalent Conditions in Periurban Communities in the State of Rio de Janeiro, Brazil by Deiviane A. Calegar, Kerla J. L. Monteiro, Andressa B. Gonçalves, Márcio N. Boia, Lauren H. Jaeger, Beatriz C. Nunes, Filipe A. Carvalho-Costa

“…Infection with G. duodenalis was significantly more frequent among children living in poor families (24/187 (12.8%) vs. 16/272 (5.9%); prevalence ratio (PR) = 2.18; 95% confidence interval (CI) = 1.19–3.99; p=0.011). …”
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Transcriptome and weighted gene co-expression network analysis of jujube (Ziziphus jujuba Mill.) fruit reveal putative genes involved in proanthocyanin biosynthesis and regulation by Wenqiang Wang, Yunfeng Pu, Hao Wen, Dengyang Lu, Min Yan, Minzhe Liu, Minyu Wu, Hongjin Bai, Lirong Shen, Cuiyun Wu

“…Sixteen genes encoding 9 families of transcriptional factors (i.e., MYB, bHLH, ERF, bZIP, NAC, SBP, MIKC, HB, WRKY) were considered as hub genes. …”
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Clinical-epidemiological Characterization of Suicide in Elder Adults by Wilfredo Valiente Morejón, Bárbara Junco Sena, Yoel Padrón Vega, Yisel de la Caridad Ramos Águila, Alina Rodríguez Méndez

“…The most frequent suicides occurred in old men with elementary school level, without working or marital bond and living with other people but with noticeable problems in the familial structure and functioning. The most frequent method was hanging. …”
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Ichthyoarchaeological perspectives on roles of fish and red meat during Indus Civilization in Gujarat, India by G. S. Abhayan, Pramod P. Joglekar, Pramod P. Joglekar, P. Ajithprasad, S. V. Rajesh, Pankaj Goyal, Brad Chase, Jeevan Kharakwal, Prabodh Shirvalkar

“…Analysis of fishbone assemblages from Indus sites such as Bagasra, Kanmer, Shikarpur, Kotada Bhadli, and Navinal in Gujarat has identified 24 fish species from 14 families. Evidence of anthropogenic activities such as cut marks, charring, and chewing on the bones suggests various aspects of fish consumption. …”
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Action against birth defects: if not now, when? by Kathleen Strong, Judith Robb-McCord, Salimah Walani, Cecilia Mellado, Lorenzo D. Botto, Guillermo Lay-Son, Theresa Diaz, Tahmina Banu, Kokila Lakhoo, Anshu Banerjee

“…Survivors face long-term morbidity and lifelong disability which compounds the health and economic woes of individuals, families, communities and society as a whole. Demographic changes in sub-Saharan Africa portend a growing number of births with 1.6 billion projected from 2021 to 2050. …”
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Pooled prevalence and determinants of household satisfaction with the community-based health insurance (CBHI) scheme in Ethiopia: a systematic review and meta-analysis by Getasew Berhanu, Yodit Abebe, Gizaw Sisay, Kassahun Animut

“…Since 2011, Ethiopia has implemented a community-based health insurance program to improve universal health coverage and promote access to health care by reducing health expenditures for low-income families. Various studies on household satisfaction with the CBHI scheme and its determinants have been undertaken in Ethiopia, and the results have been inconsistent across regions, with significant variability. …”
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Exploring nutritional risks of the specific carbohydrate diet: food and nutrient intake in children with juvenile idiopathic arthritis by Naima Hagström, Afsaneh Koochek, Eva Warensjö Lemming, Anders Öman, Henrik Arnell, Lillemor Berntson

“…Diet is considered a key research priority for juvenile idiopathic arthritis (JIA), garnering considerable interest from affected families. Despite this, research studies focusing on dietary interventions remain scarce. …”
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Influence of MHC on genetic diversity and testicular expression of linked olfactory receptor genes by Mingue Kang, Byeongyong Ahn, Jae Yeol Shin, Hye-Sun Cho, Jongan Lee, Chankyu Park

“…Abstract Background Olfactory receptor (OR) genes are highly polymorphic and form extensive families that recognize a wide range of vertebrate odorants. …”
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Behaviours preceding suicides at railway and underground locations: a multimethodological qualitative approach by Lisa Marzano, Jay-Marie Mackenzie, Jo Borrill, Emily Hawkins, Bob Fields, Ian Kruger, Ian Noonan

“…Objectives Suicides by train have devastating consequences for families, the rail industry, staff dealing with the aftermath of such incidents and potential witnesses. …”
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Assessing the impact of paternal emigration on children ‘left-behind’—A cohort analysis by Natalia Norori, Lucy Barrass, Maria Theresa Redaniel, Nanette R. Lee, Laura D. Howe, Duleeka Knipe

“…This may reflect beneficial effects of paternal migration and/or pre-existing socioeconomic and health differences amongst families who do and do not experience paternal migration.…”
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Qualitative and quantitative characteristics of black patch trait in Oujiang color common carp by Ke Jing, Huifan Chen, Nusrat Hasan Kanika, Penghui Zhang, Roland Nathan Mandal, Chunxiao Zeng, Zhiyi Zhang, Jun Wang, Chenghui Wang

“…The black patches in Oujiang color common carp (Cyprinus carpio var. color) encompasses both the formation of patches and their intricate color distribution, and has been considered as the qualitative trait. Using the crossing families of the two kinds of body color patterns in this carp, ''RB'' (red with big black patches) and ''WW'' (white body), we found Mendel's laws of inheritance patterns of black patches in Oujiang color common carp, suggesting the black patches would be controlled by single dominant gene and looked as a qualitative trait. …”
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An adenosine analog shows high antiviral potency against coronavirus and arenavirus mainly through an unusual base pairing mode by Xiaoying Jia, Xuping Jing, Ming Li, Minli Gao, Yao Zhong, Entao Li, Yang Liu, Rui Li, Guoqiang Yao, Qiaojie Liu, Minmin Zhou, Yuxia Hou, Linfeng An, Yibao Hong, Shanshan Li, Jiancun Zhang, Wei Wang, Kaiming Zhang, Peng Gong, Sandra Chiu

“…However, most ribose-modified NAs do not present broad-spectrum features, likely due to differences in ribose-RdRP interactions across virus families. Here, we show that HNC-1664, an adenosine analog with modifications both in ribose and base, has broad-spectrum antiviral activity against positive-strand coronaviruses and negative-strand arenaviruses. …”
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Genotypic Spectrum in a Cohort of Sri Lankan Patients With Homocystinuria by Hewa Warawitage Dilanthi, Kandana Liyanage Subhashinie Jayasena, Nambage Dona Priyani Dhammika, Neluwa Liyanage Ruwan Indika, Matara Mahavidanage Nishani De Silva, Imalke Kankananarachchi, Pushpa Malkanthi Gardiye Punchihewa, Dharma Irugalbandara, Sabine Schroeder, Kosala Karunaratne, Eresha Jasinge

“…We determined the variants in CBS gene in 14 Sri Lankan patients with homocystinuria, from 9 unrelated families. The clinical features and the biochemical response to pyridoxine were studied for further correlations. …”
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Ecology and phenology of the bat tick Argas (Carios) dewae (Acari: Argasidae) by Lisa Godinho, Emile van Lieshout, Stephen Griffiths, Mackenzie L. Kwak, Ala Tabor

“…This paper also reports the first records of A. dewae from 6 bat species in 3 bat families (Miniopteridae: Miniopterus australis; Molossidae: A. australis; Vespertilionidae: Chalinolobus morio, Myotis Macropus, Vespadelus darlingtonia, Vespadelus regulus) and a second record of A. dewae from a human. …”
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Investigating the formation and evolution of plant diversity patterns in the Qiangtang Plateau based on phylofloristics approach by Xiaoping Li, Yun Han, Lei Miao, Hao Xu, Jingya Yu, Shuang Han, Faqi Zhang

“…Furthermore, using fossil data, we deduced that the emergence of seed plant families in this region dates back to the Cretaceous period (145.00 Ma), with a significant acceleration in evolutionary rates observed since the onset of the Quaternary Ice Age (2.00 Ma). …”
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