Comparative Evaluation of Tear Film and Corneal Surface in Chronic Smokers and Non Smokers: A Cross-sectional Study by Ruchi Dabas, Meena Kumari, Manisha Rathi, Monika Dahiya, Rajni Yadav, Sumit Sachdeva

“…Tobacco smoke is a well-documented ocular irritant that exacerbates Dry Eye Disease (DED) and its associated symptoms. Aim: To compare tear film and corneal surface parameters in chronic smokers and non smokers. …”
Get full text

Episcleral spread of ciliochoroidal melanoma following surgeries: a case report by E.E. Grishina, I.D. Kim, E.N. Izotova

“…Follow-up of the patient with the misdiagnosis of benign eye disease continued for 20 years. The cataract and glaucoma surgeries were carried out. …”
Get full text

Change in Ocular Surface Staining during Eyelid Warming Is Related to Tear Cytokine Levels by Erlend C. S. Landsend, Jonatan Olafsson, Xiaoran Lai, Hans C. D. Aass, Tor P. Utheim

“…To investigate the changes in the tear cytokine profile of patients with meibomian gland dysfunction (MGD) treated with eyelid warming and to correlate these changes with clinical parameters for dry eye disease (DED). Methods. Seventy patients with MGD were included and treated with the warming of eyelids. …”
Get full text

Extracellular MMP-9-Based Assessment of Ocular Surface Inflammation in Patients with Primary Open-Angle Glaucoma by Anna Zaleska-Żmijewska, Ewa Strzemecka, Zbigniew M. Wawrzyniak, Jacek P. Szaflik

“…Objective assessment of dry eye disease (DED) severity and ocular inflammation using the InflammaDry® test for extracellular matrix metalloproteinase-9 (MMP-9) and the impact of antiglaucoma eye drops in people with primary open-angle glaucoma (POAG). …”
Get full text

Change in the Foveal Avascular Zone and Macular Capillary Network Density after Hyperbaric Oxygen Therapy in Healthy Retina by Sadık Görkem Çevik, Bekir Selim Bağlı

“…Methods: The study was conducted in volunteers who received HBO2 treatment but did not have any eye disease. Patients underwent detailed eye examinations including dilated fundus examination, visual acuity, and refraction before being admitted for HBO2 therapy. …”
Get full text

Anatomical and Visual Outcomes after LASIK Performed in Myopic Eyes with the WaveLight® Refractive Suite (Alcon® Laboratories Inc., USA) by Imene Salah-Mabed, Sarah Moran, Emmanuelle Perez, Guillaume Debellemanière, Damien Gatinel

“…Besides, we can assume that the patients’ quality of vision depends more on the postoperative dry eye disease generated by the laser than on the induced HOAs.…”
Get full text

Computer vision syndrome: neuro- and pathophysiological aspects (analytical review) by R.R. Akhmadeev, T.R. Mukhamadeev, E.R. Shammasova

“…</p> <p> <b>Keywords: </b>computer vision syndrome, dry eye disease, accommodation, pathogenesis, neurophysiology, visual motor integration. …”
Get full text

Tear neuropeptides are associated with clinical symptoms and signs of dry eye patients by Yirou Zhang, Hong Zhang, Xingyu Zhu, Han Ye, Kan Yang, Xujiao Zhou, Jiaxu Hong

“…Purpose To evaluate levels of 3 tear-soluble neuropeptides in dry eye patients and to identify the correlations with clinical signs and symptoms.Methods A total of 16 dry eye patients and 12 healthy volunteers were enrolled. Dry eye disease (DED) diagnosis was based on the 2017 Report of the Tear Film & Ocular Surface Society International Dry Eye Workshop (TFOS DEWS II). …”
Get full text

Unveiling molecular insights: in silico exploration of TLR4 antagonist for management of dry eye syndrome by Kothandan Sudhakar, Neeru Dugar, Srikanth Jupudi, Ravichandran Ashwin, Kuppusamy Gowthamarajan

“…Background Dry eye disease is the most commonplace multifractional ocular complication, which has already affected millions of people in the world. …”
Get full text

Rhegmatogenous retinal detachment: current treatment approaches by A.V. Doga, D.O. Shkvorchenko, L.A. Kryl, M.R. Taevere, D.A. Buryakov

“…&nbsp;Fedorov NMRC “MNTK “Eye Microsurgery”, Moscow, Russian Federation</b> </p> <p> <i>Rhegmatogenous retinal detachment (RRD) is a severe eye disease that may result in low vision or blindness in the lack of surgery. …”
Get full text

An injectable shape-adaptive hydrogel system for subconjunctival injuries: In situ and permanently releases rapamycin to prevent fibrosis via promoting autophagy by Xue Sun, Haohao Cui, Jingfan Li, Boyuan An, Ruixing Liu, Zhihua Guo, Dandan Chu, Xingchen Geng, Bingbing Cui, Lei Zhu, Jingguo Li, Zhanrong Li

“…Subconjunctival fibrosis (SCF) is a common and refractory eye disease that is a serious threat to vision. The severe side effects of existing drugs and low drug bioavailability due to the ocular barrier are major challenges in SCF treatment. …”
Get full text

TACSTD2 in gelatinous drop-like corneal dystrophy: variant functional analysis and expression in the cornea after limbal stem cell transplantation by Liubov O. Skorodumova, Ekaterina N. Grafskaia, Daria D. Kharlampieva, Dmitry I. Maltsev, Tatiana V. Petrova, Alexandra V. Kanygina, Elena V. Fedoseeva, Pavel V. Makarov, Boris E. Malyugin

“…Abstract Gelatinous drop-like corneal dystrophy (GDLD) is a rare autosomal recessive eye disease. GDLD is characterized by the loss of barrier function in corneal epithelial cells (CECs) and amyloid deposition due to pathogenic variants in the TACSTD2 gene. …”
Get full text

The amplitude of low frequency fluctuation and spontaneous brain activity alterations in age-related macular degeneration by Yan Yan Zhang, Jin Yu Hu, Qian Ling, San Hua Xu, Min Kang, Hong Wei, Jie Zou, Quanyong Yi, Gang Tan, Yi Shao, Yi Shao

“…BackgroundWet age-related macular degeneration (wAMD) is a vision-threatening eye disease worldwide. The amplitude of low-frequency fluctuation (ALFF) method was used to observe changes in spontaneous brain activity, which may help to investigate the underlying pathological mechanism of AMD.MethodsEighteen patients with wAMD and 18 age- and gender-matched healthy controls (HCs) were recruited. …”
Get full text

Protocol for a mixed-methods randomised controlled trial evaluating the psychosocial effects of an expressive arts-based intervention on adults with age-related macular degeneratio... by Qing Li, Temmy Lee Ting Lo, Rainbow Tin Hung Ho, Adrian Ho Yin Wan, Ted Chun Tat Fong, Caitlin Kar Pui Chan, Allen Ming Yan Cheong, Wai Chi Chan

“…Introduction Age-related macular degeneration (AMD) is a prevalent eye disease among middle-aged and older adults. AMD leaves the patient with irreversible deteriorating vision, which profoundly impacts their daily lives and psychosocial well-being. …”
Get full text

Serum Inflammatory Cytokines and Growth Factors in Patients with Sjögren’s Syndrome and Diabetes Mellitus by Yalçın Karaküçük, Sema Yilmaz, Ali Unlu, Banu Bozkurt, Şule Nur Acar Duyan

“…Abstract Background/ Aims: Sjögren’s syndrome (SS) and diabetes mellitus (DM) are common causes of dry eye disease (DED) and autologous serum is used when artificial tears are not sufficient. …”
Get full text

Clinical and genetic aspects of albinism by V.V. Kadyshev, S.A. Ryazhskaya, O.V. Khalanskaya, N.V. Zhurkova, R.A. Zinchenko

“…., Griscelli syndrome, Waardenburg syndrome, Aland Island eye disease, etc.) also occurs. Each case of albinism requir es an accurate molecular genetic diagnosis to provide a personalized treatment approach, predict life expectancy and health status, and plan pregnancy.…”
Get full text

IOP-lowering therapy and ocular surface in glaucoma. Part 1. The effects of drug substances of glaucoma medications on the ocular surface by A.V. Antonova, V.P. Nikolaenko, V.V. Brzheskiy

“…</i> </p> <p> <i><b>Keywords</b>: glaucoma, IOP-lowering treatment, ocular surface, dry eye disease, Ocular Surface Disease Index, inflammation, preservatives, benzalkonium chloride, preservative-free medication.…”
Get full text

Clinical Features of Optic Disc Drusen in an Ophthalmic Genetics Cohort by Jasmine Y. Serpen, Lev Prasov, Wadih M. Zein, Catherine A. Cukras, Denise Cunningham, Elizabeth C. Murphy, Amy Turriff, Brian P. Brooks, Laryssa A. Huryn

“…As ODD can be associated with visual field defects further compromising already degenerating visual function in patients with retinal degenerations, it is important to further our knowledge of ODD in inherited eye disease. The present study aims to evaluate prevalence, demographic features, and optic disc parameters of eyes with superficial ODD in inherited eye conditions. …”
Get full text

Combined Low-Level Light Therapy and Intense Pulsed Light Therapy for the Treatment of Dry Eye in Patients with Sjögren’s Syndrome by Matteo Di Marino, Paola Conigliaro, Francesco Aiello, Claudia Valeri, Clarissa Giannini, Raffaele Mancino, Stella Modica, Carlo Nucci, Roberto Perricone, Massimo Cesareo

“…To evaluate the effects of combined intense pulsed light therapy (IPL) and low-level light therapy (LLLT) in dry eye disease (DED) in patients affected by Sjögren’s syndrome. …”
Get full text

Perspectives of proteomic analysis in ophthalmology by A.A. Krylova, A.V. Zakharchuk, O.I. Krivosheina, S.I. Pekov, I.A. Popov

“…The results of proteomic mapping of tear and aqueous humor in dry eye disease, keratoconus, glaucoma, cataract, age-related macular degeneration, and diabetic retinopathy are described. …”
Get full text