Sensory alterations and immunological changes during the chronification of postsurgical pain: a study protocol for a prospective observational cohort study by Leo Koenderman, Niels Eijkelkamp, Frank J P M Huygen, Roel J H Custers, Marjelle E C van Driel, Nadine van Veenendaal, Lisette Margaretha Vernooij, L Timmerman, Diyar Delawi, M Rijsdijk

“…The ‘Sensory Changes and Immunological parameters in Postsurgical pain’ study (SCIP-Pain study) was designed to test this hypothesis and identify sensory alterations and changes in the immunological response that are related to the development of CPSP with neuropathic features.Methods and analysis This protocol describes the SCIP-Pain study—an ongoing prospective observational cohort study involving 150 adult patients undergoing elective lower extremity orthopaedic surgery. Study participants complete questionnaires, undergo quantitative sensory testing (QST) and provide blood samples to assess the immunological response at various time points: before surgery, 2 weeks and 3 months after surgery. …”
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Review on Synthesis Method, Classification and AdsorptionSeparation and Sensing Application of Metal-Organic Frameworks (MOFs) Based Composites by Aklilu Melese, Kenaegzer Mulate, Abdu Hussen, Afework Hailekiros, Walelign Wubet

“…The structural characteristics, classification, The most widely used and successful strategies for MOFs composite synthesis are presented like (Encapsulation method, Solvothermal method, Solution impregnation, and Click chemistry (reaction) method), numerous characterization techniques and their applications MOFs composite have all been covered in this review. Crystals with extremely high porosity and good thermal and chemical stability can be produced by carefully choosing the MOF ingredients. …”
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A case of 49,XXXYY followed-up from infancy to adulthood with review of literature by Junko Kanno, Akinobu Miura, Sayaka Kawashima, Hirohito Shima, Dai Suzuki, Miki Kamimura, Ikuma Fujiwara, Masayuki Kamimura, Mitsugu Uematsu, Masataka Kudo, Atsuo Kikuchi

“…49,XXXYY is an extremely rare sex chromosomal aneuploidy (SCA), with only seven cases reported worldwide to date. …”
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Advancing date palm cultivation in the Arabian Peninsula and beyond: Addressing stress tolerance, genetic diversity, and sustainable practices by Soumya Koippully Manikandan, Dharshini Jenifer. A, Nisarga K. Gowda, Vaishakh Nair, Rami Al-Ruzouq, Mohamed Barakat A. Gibril, Fouad Lamghari, John Klironomos, Maryam Al Hmoudi, Mohamed Sheteiwy, Ali El-Keblawy

“…However, sustainability challenges persist due to various abiotic stresses, such as salinity, temperature extremes, drought, soil factors, and biotic stresses, including diseases and pests. …”
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The impact of nutritional status on centenarians’ physical, mental, and functional health by Ivan David Lozada-Martinez, Laura Vindas-Meza, Sandra Castelblanco-Toro, Juan Carlos Salazar-Uribe, Juan-Manuel Anaya

“…Summary: Background & Aims: Nutrition has been described as a lifestyle factor strongly associated with health phenotypes in extreme longevity. However, little is known about its relationship with health-related outcomes in centenarians. …”
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Evaluating machine learning models for supernova gravitational wave signal classification by Y Sultan Abylkairov, Matthew C Edwards, Daniil Orel, Ayan Mitra, Bekdaulet Shukirgaliyev, Ernazar Abdikamalov

“…We test convolutional and recurrent neural networks, as well as six classical algorithms: random forest, support vector machines, naïve Bayes(NB), logistic regression, k -nearest neighbors, and eXtreme gradient boosting. All models, except NB, achieve over 90 per cent accuracy on our dataset. …”
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Parathyroid Carcinoma in the Setting of Tertiary Hyperparathyroidism: Case Report and Review of the Literature by Federico Cappellacci, Fabio Medas, Gian Luigi Canu, Maria Letizia Lai, Giovanni Conzo, Enrico Erdas, Pietro Giorgio Calò

“…Parathyroid carcinoma is one of the rarest cancers in normal population, and it is extremely uncommon in the setting of tertiary hyperparathyroidism. …”
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Optimization of Polyphenol Extraction from Purple Corn Pericarp Using Glycerol/Lactic Acid-Based Deep Eutectic Solvent in Combination with Ultrasound-Assisted Extraction by Ravinder Kumar, Sherry Flint-Garcia, Miriam Nancy Salazar Vidal, Lakshmikantha Channaiah, Bongkosh Vardhanabhuti, Stephan Sommer, Caixia Wan, Pavel Somavat

“…Purple corn pericarp, a processing waste stream, is an extremely rich source of phytochemicals. Optimal polyphenol extraction parameters were identified using response surface methodology (RSM) by combining a deep eutectic solvent (DES) and ultrasound-assisted extraction (UAE) method. …”
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Mesh Migration into the Neobladder and Ileum with Complicated Fistula Formation following Incisional Hernia Repair by Masatsugu Kuroiwa, Masato Kitazawa, Yusuke Miyagawa, Futoshi Muranaka, Shigeo Tokumaru, Satoshi Nakamura, Makoto Koyama, Yuta Yamamoto, Nao Hondo, Takehito Ehara, Satoru Miyazaki, Hirokazu Tanaka, Yuji Soejima

“…However, its postoperative complications reportedly include mesh infection, adhesions, and fistula formation in other organs. Here, we report an extremely rare case of mesh migration into the neobladder and ileum with entero-neobladder and neobladder-cutaneous fistulas. …”
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Development of Cutaneous Leishmaniasis after Leishmania Skin Test by Paulo R. Machado, Augusto M. Carvalho, Gustavo U. Machado, Marina L. Dantas, Sérgio Arruda

“…Thirty-year-old female with a previous history of a cutaneous ulcer suspicious of leishmaniasis 20 years ago presented with a new complaint of a depressed papular lesion 8×7 mm in the right lower extremity. The lesion was of 10-day duration. Because early cutaneous leishmaniasis (CL) lesions may have a non-ulcerated appearance, a Leishmania skin test (LST) was performed on the forearm with a strong positive result (38×32 mm). …”
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Autoinflammatory Bone Diseases by Fatih Haşlak, Nergis Akay, Ümit Gül, Aybüke Günalp, Elif Kılıç Könte, Sezgin Şahin, Özgür Kasapçopur

“…Data on the diagnosis and treatment of these rare diseases are extremely limited. However, if not diagnosed and treated promptly, it can result in significant complications, including severe disability and mortality. …”
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Investigation of a transformer-based hybrid artificial neural networks for climate data prediction and analysis by Shangke Liu, Ke Liu, Zheng Wang, Yuanyuan Liu, Bin Bai, Rui Zhao

“…IntroductionClimate change isone of the major challenges facing the world today, causing frequent extreme weather events that significantly impact human production, life, and the ecological environment. …”
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α₁-Acid Glycoprotein with Highly Fucosylated Glycans as a Potential Diagnostic Marker for Early Detection of Hepatobiliary and Pancreatic Cancers by Mizuki Endo, Shin Yazawa, Rie Sano, Takehiko Yokobori, Ken Shirabe, Hiroshi Saeki

“…In contrast, all the tumor markers exhibited low sensitivity and accuracy, even though they commonly had extremely high (≥80%) specificity. Further, a significant number of patients in both early and advanced clinical stages were found to be false negative in these tumor makers but were found to be positive in the fAGP level. …”
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The Prediction of Day‐to‐Day Occurrence of Low Latitude Ionospheric Strong Scintillation Using Gradient Boosting Algorithm by Xiukuan Zhao, Guozhu Li, Haiyong Xie, Lianhuan Hu, Wenjie Sun, Sipeng Yang, Yi Li, Baiqi Ning, Hisao Takahashi

“…Using the long‐term ground‐based GNSS receiver and ionosonde data collected in the Brazilian longitude sector during 2012–2020, an ionospheric strong scintillation prediction model based on the gradient boosting algorithms extreme gradient boosting (XGBoost), light gradient boosting machine (LightGBM), and CatBoost is created and tested. …”
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Diverged Populations Admixture Bolsters Genetic Diversity of a New Island Dibbler (Parantechinus apicalis) Population, but Does Not Prevent Subsequent Loss of Genetic Variation by Rujiporn Thavornkanlapachai, Harriet R. Mills, Kym Ottewell, Cathy Lambert, J. Anthony Friend, Daniel J. White, Zahra Aisya, W. Jason Kennington

“…Nevertheless, genetic contributions in the translocated population became equal over time with no parental purebreds, suggesting an extreme excess of hybrids across multiple years. While genetic variation in the translocated population was comparable or higher than the source populations, the increase was short‐lived. …”
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Sensor Image, Anomaly Detection Method for Hydroelectric Dam Structure Using Sensors Measurements and Deep Learning by Van-Phuong Ha, Dinh-Van Nguyen, Trong-Chuong Trinh, Duc-Cuong Quach, Van HuyBui

“…This often results in the collection of extremely imbalanced datasets. Furthermore, the sensor measurements are highly correlated with each other along the spatial and temporal axes. …”
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Estimation of evaporation in Andalusian reservoirs: Proposal of an index for the assessment and classification of dams by Santiago García-López, Marcia Salazar-Rojas, Mercedes Vélez-Nicolás, Jorge. M.G.P. Isidoro, Verónica Ruiz-Ortiz

“…Evaporative losses represent 1.1 % of inflows in the most efficient reservoirs, while in others, losses exceed 30 %, reaching 54 % in the most extreme case.…”
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An optimized method for AUV trajectory model in benthonic hydrothermal area based on improved slime mold algorithm by Chunmeng Jiang, Yiming Tang, Jianguo Wang, Wenchao Zhang, Min Zhou, Jiaying Niu, Lei Wan, Guofang Chen, Gongxing Wu, Xide Cheng

“…The results showed that the improved SMA shortened the search process, effectively avoided the local extreme values, and generated a high-precision desired trajectory model in a shorter time. …”
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Unravelling Lithium Interactions in Non-Flammable Gel Polymer Electrolytes: A Density Functional Theory and Molecular Dynamics Study by Nasser AL-Hamdani, Paula V. Saravia, Javier Luque Di Salvo, Sergio A. Paz, Giorgio De Luca

“…Lithium metal batteries (LiMBs) have emerged as extremely viable options for next-generation energy storage owing to their elevated energy density and improved theoretical specific capacity relative to traditional lithium batteries. …”
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The influence of internal spatial coupling characteristics of blue-green space on cooling benefit in metropolitan areas: Evidence form Hangzhou, China by Qianru Lu, Weifeng Qi, Dongye Yang, Mingyu Zhang

“…The influence of spatial coupling relationships varies across different land-use densities, with more pronounced effects under typical high-temperature conditions compared to extreme heat. These findings offer urban planners valuable insights into optimizing the spatial relationship of blue-green spaces, helping to maximize their cooling benefit in limited space resource in metropolitan, ultimately enhancing urban resilience to climate change.…”
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