Showing 161 - 180 results of 635 for search '"extracellular matrix"', query time: 0.06s Refine Results
  1. 161

    The Role of Hyaluronan in Innate Defense Responses of the Intestine by Carol A. de la Motte, Sean P. Kessler

    Published 2015-01-01
    “…Hyaluronan is an abundant extracellular matrix component prevalent in the vertebrate intestinal tract. …”
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  2. 162

    Principles of Medical Biochemistry / by Meisenberg, Gerhard

    Published 2017
    Table of Contents: “…Introduction to biomolecules -- Introduction to protein structure -- Oxygen-binding proteins : hemoglobin and myoglobin -- Enzymatic reactions -- Coenzymes -- DNA, RNA, and protein synthesis -- The human genome -- Protein targeting and proteostasis -- Introduction to genetic diseases -- Viruses -- DNA technology -- Biological membranes -- The cytoskeleton -- The extracellular matrix -- Extracellular messengers -- Intracellular messengers -- Plasma proteins -- Defense mechanisms -- Cellular growth control and cancer -- Digestive enzymes -- Introduction to metabolic pathways -- Glycolysis, tricarboxylic acid cycle, and oxidative phosphorylation -- Oxygen deficiency and oxygen toxicity -- Carbohydrate metabolism -- The metabolism of fatty acids and triglycerides -- The metabolism of membrane lipids -- Lipid transport -- Amino acid metabolism -- Metabolism of iron and heme -- The metabolism of purines and pyrimidines -- Micronutrients -- Integration of metabolism.…”
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  3. 163

    Combined Effects of Estrogen and Mechanical Loading on Anterior Cruciate Ligament Fibroblast Biosynthesis by Xuhui Liu, Zong-Ping Luo

    Published 2005-01-01
    “…In a recent study, our group demonstrated a negative combined effect of estrogen and mechanical loading on the gene expression of major extracellular matrix component molecules in ACL fibroblasts.…”
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  4. 164

    Sitagliptin and the Blood-Retina Barrier: Effects on Retinal Endothelial Cells Manifested Only after Prolonged Exposure by Anja Jäckle, Focke Ziemssen, Eva-Maria Kuhn, Jürgen Kampmeier, Gerhard K. Lang, Gabriele E. Lang, Helmut Deissler, Heidrun L. Deissler

    Published 2020-01-01
    “…Because both associated proteins are important for adhesion of iBREC to the extracellular matrix, the observed low CI might be caused by weakened attachment of the cells. …”
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  5. 165

    Progress in Study of Low-Intensity Pulsed Ultrasound Acting on Inflammation-Related Signaling Pathways in Knee Osteoarthritis by OUYANG Hui, LIN Xingjin, WANG Jinying, SHEN Longbin, WANG Chengdong

    Published 2023-10-01
    “…They appear in multiple pathogenic signaling pathways of KOA, regulate the intracellular activity of KOA and play an important role in pathological processes such as chondrocyte destruction, extracellular matrix reduction, abnormal cartilage remodeling, subchondral ossification, and synovial inflammation. …”
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  6. 166

    The impact of glucocorticoid receptor transactivation on context-dependent cell migration dynamics by Szonja Polett Pósa, Éva Saskői, Lili Bársony, Lőrinc Pongor, Fanni Fekete, János Papp, Anikó Bozsik, Attila Patócs, Henriett Butz

    Published 2025-02-01
    “…RNA sequencing revealed dex’s impact on cell adhesion and extracellular matrix signalling in TN cells and on DNA replication in ER + cells. …”
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  7. 167

    Engineered CAF-cancer cell hybrid membrane biomimetic dual-targeted integrated platform for multi-dimensional treatment of ovarian cancer by Yuwei Yao, Jiarui Zhang, Kexin Huang, Yingying Peng, Shuangshuang Cheng, Shuangge Liu, Ting Zhou, Jinhua Chen, Haojia Li, Yingchao Zhao, Hongbo Wang

    Published 2025-02-01
    “…The nanoparticle PH20/CCM@PMCS could penetrate the extracellular matrix of tumor tissues and target both cancer cells and CAFs. …”
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  8. 168

    Distinct Murine Pancreatic Transcriptomic Signatures during Chronic Pancreatitis Recovery by Yinjie Zhang, Baibing Yang, Joy M. Davis, Madeline M. Drake, Mamoun Younes, Qiang Shen, Zhongming Zhao, Yanna Cao, Tien C. Ko

    Published 2021-01-01
    “…In conclusion, we identified a distinct set of DEGs in association with extracellular matrix and cancer cell activities to contrast CP and CPR. …”
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  9. 169

    In Sickness and in Health: Perineuronal Nets and Synaptic Plasticity in Psychiatric Disorders by Harry Pantazopoulos, Sabina Berretta

    Published 2016-01-01
    “…Rapidly emerging evidence implicates perineuronal nets (PNNs) and extracellular matrix (ECM) molecules that compose or interact with PNNs, in the pathophysiology of several psychiatric disorders. …”
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  10. 170

    Fine Tuning Cell Migration by a Disintegrin and Metalloproteinases by D. Dreymueller, K. Theodorou, M. Donners, A. Ludwig

    Published 2017-01-01
    “…Both basic cell migration and migration towards chemotactic stimulus consist of changes in cell polarity and cytoskeletal rearrangement, cell detachment from, invasion through, and reattachment to their neighboring cells, and numerous interactions with the extracellular matrix. The different steps of immune cell, tissue cell, or cancer cell migration are tightly coordinated in time and place by growth factors, cytokines/chemokines, adhesion molecules, and receptors for these ligands. …”
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  11. 171

    Regulatory Effect of Inflammatory Mediators in Intervertebral Disc Degeneration by Zhangfu Li, Honghao Yang, Yong Hai, Yunzhong Cheng

    Published 2023-01-01
    “…It is related to changes in tissue structure and function, including the breakdown of the extracellular matrix (ECM), aging, apoptosis of the nucleus pulposus, and biomechanical tissue impairment. …”
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  12. 172

    Matrix Metalloproteinases in Inflammatory Bowel Disease: An Update by Shane O’Sullivan, John F. Gilmer, Carlos Medina

    Published 2015-01-01
    “…Through digestion of the extracellular matrix and cleavage of bioactive proteins, a huge diversity of roles have been revealed for the MMPs in IBD, where they have been shown to regulate epithelial barrier function, immune response, angiogenesis, fibrosis, and wound healing. …”
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  13. 173

    SOX9: a key transcriptional regulator in organ fibrosis by Yishuo Li, Yue Xing, Ning Liu, Bin Liu, Zhihui Wang

    Published 2025-02-01
    “…Many disorders are associated with the process of fibrosis; moreover, fibrosis is a common symptom of chronic inflammatory diseases, characterized by the accumulation of excessive components in the extracellular matrix through different signaling pathways. …”
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  14. 174

    Variations to the Nanotube Surface for Bone Regeneration by Christine J. Frandsen, Karla S. Brammer, Sungho Jin

    Published 2013-01-01
    “…A particularly fascinating area of research involves the study of nanostructured surfaces, which are believed to enhance osteogenic behavior, possibly due to the mimicry of components of the extracellular matrix of bone. There is a growing body of data that emphasizes the promise of the titanium oxide (TiO2) nanotube architecture as an advanced orthopedic implant material. …”
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  15. 175

    Leukocytes: The Double-Edged Sword in Fibrosis by Jakub Kryczka, Joanna Boncela

    Published 2015-01-01
    “…Skin tissue scar formation and fibrosis are often characterized by the increased production and deposition of extracellular matrix components, accompanied by the accumulation of a vast number of myofibroblasts. …”
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  16. 176

    The impact of prolonged blockade of the releasing hormone on alterations in cardiac macrophage polarisation subsequent to quercetin administration in rats by T.A. Voroshylova, V.I. Shepitko, Ye.V. Stetsuk, N.V. Boruta, O.V. Vilkhova, M.V. Rud, G.S. Puzyryov, O.V. Sych, А.A. Miahkokhlib

    Published 2024-12-01
    “…Cardiomyocytes represent the contractile units of the myocardium, while the maintenance and renewal of the extracellular matrix is a function of fibroblasts. The extracellular matrix provides structural support and mechanical signals for resident cells, and stores biologically active signaling molecules. …”
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  17. 177

    Effects of the Highly COX-2-Selective Analgesic NSAID Etoricoxib on Human Periodontal Ligament Fibroblasts during Compressive Orthodontic Mechanical Strain by Christian Kirschneck, Erika Calvano Küchler, Michael Wolf, Gerrit Spanier, Peter Proff, Agnes Schröder

    Published 2019-01-01
    “…Clinically dosed etoricoxib, that is, a highly selective COX-2 inhibition, did not have substantial effects on hPDL fibroblast-mediated periodontal inflammation, extracellular matrix remodeling, RANK-L/OPG expression, and osteoclastogenesis during simulated orthodontic compressive strain.…”
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  18. 178

    Angiogenesis and Its Therapeutic Opportunities by So Young Yoo, Sang Mo Kwon

    Published 2013-01-01
    “…The sophisticated multistep process is tightly regulated in a spatial and temporal manner by “on-off switch signals” between angiogenic factors, extracellular matrix components, and endothelial cells. Uncontrolled angiogenesis may lead to several angiogenic disorders, including vascular insufficiency (myocardial or critical limb ischemia) and vascular overgrowth (hemangiomas, vascularized tumors, and retinopathies). …”
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  19. 179

    The Biology and Function of Tissue Inhibitor of Metalloproteinase 2 in the Lungs by Louis Costanzo, Brian Soto, Richard Meier, Patrick Geraghty

    Published 2022-01-01
    “…During aging and disease progression, the extracellular matrix (ECM) undergoes structural changes in which elastin and collagens serve an essential role. …”
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  20. 180

    Cancer Stem Cells and Their Microenvironment: Biology and Therapeutic Implications by Eunice Yuen-Ting Lau, Nicole Pui-Yu Ho, Terence Kin-Wah Lee

    Published 2017-01-01
    “…Here, we review the significance of stromal cells, immune cells, extracellular matrix, tumor stiffness, and hypoxia in regulation of CSC plasticity and therapeutic resistance. …”
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