PreS1 deletions in genotype C HBV leads to severe hepatic inflammation and hepatocarcinogenesis via the IRE1-JNK axis by Yu-Min Choi, Junghwa Jang, Dong Hyun Kim, Ziyun Kim, Eunseo Kim, Won Hyeok Choe, Bum-Joon Kim

“…Methods: The effects of HBV replicative capacity, ER stress signaling, inflammation, cell death, and tumorigenesis resulting from PreS1 deletions were investigated through in vitro and in vivo experiments. Inhibitors of the IRE1-JNK pathway and IL6 blockade were used to examine HCC tumor load induced by preS1 deletions. …”
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Effects of taurine on growth performance, body composition and physiological responses of western white shrimp, Litopenaeus vannamei broodstock by Vahid Morshedi, Mahmoud Nafisi Bahabadi, Mansour Torfi Mozanzadeh, Amin Oujifard, Naser Agh, Khalegh Maneii, Ahmad Qasemi, Nehzat Bakhshi, Hadi Ebrahimi, Rezvan Tamadoni, Shirin Hamedi, Reza Bagherpour, Fatemeh Solimani

“…To evaluate the effects of Tau on growth, body composition, digestive enzymes, and haemolymph biochemical parameters, sampling was taken at the end of the experiment. Results and discussion: The results showed that final weight, specific growth rate, weight gain, condition factor, and survival of shrimp fed with the supplemented diets with Tau had no significant differences than the control group (p>0.05). …”
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Investigating the Effect of Different Levels of Butyric Acid Glycerides and Clove Oil on Growth Performance, Blood Parameters and Tibia Bone Characteristics of Broiler Chickens by Seyyedeh azam khatami, Mir Daryoush Shakouri, Nemat Hedayat Evrigh

“…The equation of the statistical model of the experiment was according to the relation Yijk = µ + Ai + Bj + (AB)ij + eijk, where Yijk represents the numerical value of each observation, µ is the population mean, Ai is the effect of butyric acid glycerides (0 and 0.2%), Bj was the effect of clove oil (0, 500 and 1000 mg/kg), ij (AB) was the interaction effect of butyric acid glycerides and clove oil, and eijk was the experimental error.Results and Discussion: The results showed that the addition of 0.2% butyric acid glycerides in the diet of broiler chickens reduced feed intake, body weight and daily weight gain compared to the control group (P<0.05). …”
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Vegetable Crop Growth Modeling in Digital Twin Platform Based on Large Language Model Inference by ZHAO Chunjiang, LI Jingchen, WU Huarui, YANG Yusen

“…The results of the experiments demonstrating the efficacy of the proposed system in addressing the complexities of vegetable crop growth modeling. …”
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Width evolution of channel belts as a random walk by J. M. Turowski, J. M. Turowski, F. McNab, A. Bufe, A. Bufe, S. Tofelde

“…Model predictions compare well to data of sediment age distributions measured at field sites and the temporal evolution of channel belts observed in flume experiments. Both comparisons indicate that a random walk approach adequately describes the lateral migration of channels and the formation of channel belts. …”
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Investigating the Effect of Chicken Manure and Potassium Sulfate on the Physiological Properties of Fenugreek )Trigonella foenum-graecum L.( Medicinal Plant by Mohammad hossein Aminifard, Sajjad Nadafa, Hassan Hassan, Mehdi Jahani

“…The investigated traits of this experiment included morphological and physiological traits, which were sampled after the plants were fruited and the pods turned yellow by removing the marginal effect.Results and Discussion The results showed that the highest level of secondary and main stem height, leaf dry weight and other growth traits were obtained with the highest level of chicken manure (2000 kg/ha), which of course was not significantly different from the level of 1000 kg/ha of chicken manure. …”
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Combined Effects of Humic Acid-Modified Magnetic Biochar and AMF on the Properties of Saline-Alkali Soil and Photosynthetic Parameters of Muskmelon by ZHANG Yating, LOU Xueyi, WU Jiarui, LIU Hongyuan, YE Binyu, XIAO Jiamin, LI Jiameng, MIAO Yining, CHEN Xinyan, LIU Yilin, TAN Yuyu, WANG Zhichao, LIU Peng

“…Moreover, by conducting pot experiments, the influence of individual fungi, individual biochar, and combined biochar-fungi (AMF+10%B, AMF+20%B) on the physicochemical properties, and enzyme activities of saline soil and alkaline soil, and the photosynthetic parameters of muskmelon were studied. …”
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Effects of <i>Enterococcus faecalis</i> Supplementation on Growth Performance, Hepatic Lipid Metabolism, and mRNA Expression of Lipid Metabolism Genes and Intestinal Flora in Geese by Siyu Sun, Yujie Zhao, Zhen Pang, Baoxia Wan, Jiaqi Wang, Zhenyu Wu, Qiuju Wang

“…Each group was divided into six replicates, with five geese per replicate. During the 45-day experiment, the control group received a basal diet, while the experimental group was provided with the same basal diet supplemented with <i>E. faecalis</i> in drinking water at a concentration of 1.0 × 10⁸ CFU/mL. …”
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Targeting NANOS1 in triple-negative breast cancer: synergistic effects of digoxin and PD-1 inhibitors in modulating the tumor immune microenvironment by Tangyi Wang, Yadian Lei, Jingwei Sun, Li Wang, Yuxin Lin, Zhijing Wu, Shoude Zhang, Chengzhu Cao, Chengzhu Cao, Chengzhu Cao, Haiyan Wang, Haiyan Wang, Haiyan Wang

“…Molecular docking identified Dig and AA as high-affinity binders of NANOS1. Animal experiments showed Dig and PD-1 inhibitor combination enhanced immunotherapy efficacy for TNBC.DiscussionThe findings from this study suggest that TOE may offer a novel therapeutic approach for TNBC by targeting NANOS1, a protein whose down-regulation is associated with improved patient outcomes. …”
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Effect of Electroacupuncture at Shuigou Acupoint on L-type Voltage-gated Calcium Channels in hippocampal CA1 region of MCAO rats by Da LONG, Ling CHEN, Yu YAO, Mingan ZENG

“…After the mice waking up, Zausinger six acupoint scale was used to the neurological function score of the mice, and the mice which scored 1 to 3 points were selected for the experiment. They were randomly divided into Shuigou group, control group and non-acupiont group according the random number method, with 10 mice in each group. …”
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Large errors in soil carbon measurements attributed to inconsistent sample processing by R. J. Even, M. B. Machmuller, M. B. Machmuller, J. M. Lavallee, J. M. Lavallee, T. J. Zelikova, T. J. Zelikova, M. F. Cotrufo, M. F. Cotrufo

“…Further, to better understand how soil processing procedures and quantification methods commonly used in soil testing laboratories affect soil C concentration measurements, we designed an internal experiment assessing the individual effect of several alternative procedures (i.e., sieving, fine grinding, and drying) and quantification methods on total (TC), inorganic (SIC), and organic (SOC) soil C concentration estimates. …”
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Annexin A8 deficiency delays atherosclerosis progression by Carmen Gutiérrez‐Muñoz, Rafael Blázquez‐Serra, Irene San Sebastian‐Jaraba, Sandra Sanz‐Andrea, Maria J. Fernández‐Gómez, Gonzalo Nuñez‐Moreno, Pablo Mínguez, Joan Carles Escolá‐Gil, Paula Nogales, Veronique Ollivier, Jose L. Martín‐Ventura, Benoit Ho‐Tin Noe, Ursula Rescher, Nerea Méndez‐Barbero, Luis M. Blanco‐Colio

“…Oxidized low‐density lipoprotein (ox‐LDL) increased AnxA8 expression in murine aortic endothelial cells (MAECs). In vitro experiments revealed that AnxA8 deficiency in MAECs suppressed P/E‐selectin and CD31 expression and secretion induced by ox‐LDL with a concomitant reduction in platelet and leukocyte adhesion. …”
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Wild grasses as the reservoirs of infection of rust species for winter soft wheat in the Northern CaucasusWild grasses as the reservoirs of infection of rust species for winter sof... by E. I. Gultyaeva, L. A. Bespalova, I. B. Ablova, E. L. Shaydayuk, Zh. N. Khudokormova, D. R. Yakovleva, Yu. A. Titova

“…Monopustular Puccinia spp. isolates were used for virulence genetics analysis. In experiments to study the specialization of rust species from wild-growing cereals on common wheat, 12 winter cultivars were used (Grom, Tanya, Yuka, Tabor, Bezostaya 100, Yubileynaya 100, Vekha, Vassa, Alekseich, Stan, Gurt, Bagrat). …”
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Evaluation of Some Cumin Ecotypes Based on Selection Index of Ideal Genotype by Masoud Golestani

“…Methods: To evaluate cumin ecotypes using the SIIG, an experiment was conducted on 12 cumin ecotypes based on a randomized complete block design with three replications in the 2022-2023 cropping season. …”
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Conflict-related and sexual trauma in treatment-seeking Arabic-speaking men: a cross-sectional studyResearch in context by Max Vöhringer, Freya Specht, Christine Knaevelsrud, Birgit Wagner, Maria Böttche, Yuriy Nesterko

“…Interpretation: The results of this exploratory study reveal that a substantial proportion of Arabic-speaking treatment seeking men from different countries in the MENA region reported experiences of sexual and conflict-related trauma, which were associated with high psychological symptom scores. …”
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Detection Method of Effective Tillering of Rice in Field Based on Lightweight Ghost-YOLOv8 and Smart Phone by CUI Jiale, ZENG Xiangfeng, REN Zhengwei, SUN Jian, TANG Chen, YANG Wanneng, SONG Peng

“…[Results and Discussions]The results of field experiments showed that there were differences in the growth height of effective tillers and ineffective tillers of rice. …”
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Gut bacteria Prevotellaceae related lithocholic acid metabolism promotes colonic inflammation by Liping Chen, Zhenghao Ye, Junhua Li, Lijia Wang, Yu Chen, Meiping Yu, Jian Han, Jiangeng Huang, Dongyan Li, Yongling Lv, Kai Xiong, De’an Tian, Jiazhi Liao, Ursula Seidler, Fang Xiao

“…Through multivariate analysis, LCA was identified as the key bile acid that significantly affects colonic inflammation and the integrity of mucosal barrier. Subsequent experiments confirmed that LCA supplementation effectively mitigated the inhibitory effects of gut microbiota on colitis progression in mice, primarily through the activation of the sphingosine-1-phosphate receptor 2 (S1PR2)/NF-κB p65 signaling pathway. …”
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Effectiveness of hCMV, mEF1a and mAct promoters on driving of foreign gene expression in transgenic zebrafish by . Alimuddin, G. Yoshizaki, O. Carman, T. Takeuchi

“…Here, as the first step of study, we conducted experiment to select an appropriate construct that allows higher expression levels of masu salmon (Oncorhynchus masou) D6-desaturase gene in zebrafish (Danio rerio) in order to increase its activity for synthesizing EPA/DHA.  …”
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Effect of Sunflower (Helianthus annus L.) Hulls with Different Particle Sizes on Growth Performance and Physiological Responses of Broiler Chickens Fed Different Levels of Protein by Najibeh Beigzadeh, Smayyeh Salari, Faegheh Zaefarian, Shima Hosseinifar

“…This study investigates the performance of broilers fed on low-density crude protein diets with increasing particle size of sunflower (Helianthus annus L.) hulls.Materials and Methods: This experiment aimed to examine the effect of sunflower hull particle size on the performance and physiological response of broiler chickens fed with different protein levels. …”
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The Combined Effect of Garlic (Allium sativum) and Turmeric (Curcuma longa) Extracts to Reduce the Adverse Effects of Aflatoxin B1 in Rats by Hadi Sarir, Saeedeh Zakerian, masood didarkhah

“…The aim of this research is to investigate the effect of the combination of garlic and turmeric extract on the amount of plasma aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase, the amount of triiodothyronine, thyroxine, total antioxidant capacity, and malondialdehyde in rats intoxicated with aflatoxin B1.Materials and Methods: In this research, 64 male Wistar rats with an average body weight of 250-300 g were used to evaluate the synergistic effect of garlic and turmeric extract against the damage caused by aflatoxin B1 in the form of a completely randomized design as a factorial experiment (2×2×2). Eight groups were tested for 28 days in the animal dissection laboratory of the Faculty of Agriculture of Birjand University, observing all ethical considerations. …”
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