Evaluation method and application for in-situ stress in No. 8+9 coal seam, southern Shenfu block, northeastern margin of Ordos Basin by Jiawei WU, Wei TANG, Yanhe ZHU, Cunwu WANG, Yongjing TIAN, Jingyu ZI, Jianghao YANG, Xian SHI

Get full text

Analisis Sentimen pada Data Saran Mahasiswa Terhadap Kinerja Departemen di Perguruan Tinggi Menggunakan Convolutional Neural Network by Yuliska Yuliska, Dini Hidayatul Qudsi, Juanda Hakim Lubis, Khairul Umum Syaliman, Nina Fadilah Najwa

“…This research utilizes two CNN architectures, which are Simple CNN dan DoubleMax CNN to identify the effect of the complexity of CNN architecture to final result. Our experiments show that DoubleMax CNN has a great performance in classifying sentiment in the student’s reviews with the best Accuracy value of 98%, Recall 97%, Precision 98% and F1-Score value of 98%. …”
Get full text

Optimal selection of satellite XCO₂ images for urban CO₂ emission monitoring by A. Danjou, G. Broquet, A. Schuh, F.-M. Bréon, T. Lauvaux, T. Lauvaux

“…It uses synthetic data experiments with synthetic truth and 9920 synthetic satellite images of XCO<span class="inline-formula">₂</span> over 31 of the largest cities across the world generated with a global adaptive-mesh model, the Ocean–Land–Atmosphere Model (OLAM), zoomed in at high resolution over these cities. …”
Get full text

Effect of Channel Orientation and Rib Pitch-to-Height Ratio on Pressure Drop in a Rotating Square Channel with Ribs on Two Opposite Surfaces by Prabhu S. V., Arora Neelabh, Vedula R. P.

“…The study has been conducted for three Reynolds numbers, namely, 13 000, 17 000, and 22 000 with the rotation number varying from 0&#8211;<math alttext="$0.38$"> <mn>0.38</mn> </math>. Experiments have been carried out for various rib pitch-to-height ratios <math alttext="$(P/e)$"> <mrow><mo>(</mo> <mrow> <mrow><mi>P</mi><mo>/</mo><mi>e</mi></mrow> </mrow> <mo>)</mo></mrow> </math> with a constant rib height-to-hydraulic diameter ratio <math alttext="$(e/D)$"> <mrow><mo>(</mo> <mrow> <mrow><mi>e</mi><mo>/</mo><mi>D</mi></mrow> </mrow> <mo>)</mo></mrow> </math> of <math alttext="$0.1$"> <mn>0.1</mn> </math>. …”
Get full text

Kangtaizhi Granule Alleviated Nonalcoholic Fatty Liver Disease in High-Fat Diet-Fed Rats and HepG2 Cells via AMPK/mTOR Signaling Pathway by Jiaxin Zhang, Haixia Du, Menglan Shen, Zhengqi Zhao, Xinmiao Ye

“…Network pharmacology screened 42 compounds and 79 related targets related to NAFLD; HPLC analysis also confirmed six compounds in KTZG. Further experiments were also performed. In an in vivo study, SD rats were randomly divided into five groups: control (rats fed with normal diet), NAFLD (rats fed with high-fat diet), and KTZG 0.75, 1.5, and 3 groups (NAFLD rats treated with KTZG 0.75, 1.5, and 3 g/kg, respectively). …”
Get full text

A Multifunctional MIL-101-NH2(Fe) Nanoplatform for Synergistic Melanoma Therapy by Shang J, Chen Y, Wang F, Yang J, Li Y, Yang L, Liu X, Zhong Z, Yue C, Zhou M

“…Cellular studies using B16F10 cells assessed cytotoxicity, cellular uptake, migration inhibition, and colony formation suppression. In vivo experiments in melanoma-bearing mice evaluated antitumor efficacy and systemic safety through tumor growth inhibition, histological analyses, and toxicity assessments.Results: MIL@DOX@ICG exhibited a uniform octahedral structure with a particle size of approximately 139 nm and high drug loading efficiencies for DOX (33.70%) and ICG (30.59%). …”
Get full text

Exploring the Mechanisms of Iron Overload-Induced Liver Injury in Rats Based on Transcriptomics and Proteomics by Yujia Shu, Xuanfu Wu, Dongxu Zhang, Shuxia Jiang, Wenqiang Ma

“…The integrated transcriptomic and proteomic analysis suggests that HO-1 and Lnc286.2 are potentially significant in iron overload-induced liver injury in rats. In vitro experiments utilizing ferric ammonium citrate (FAC) were conducted to establish an iron overload model in rat liver-derived BRL-3A cells. …”
Get full text

Betulinic Acid Inhibits the Metastasis of Colon Cancer Cells through Regulating TGF-β/Smad Signaling Pathway by Xiaoying LIN, Aling SHEN, Meizhu WU, Ying CHENG, Xiaoping CHEN, Huixin LIU, Liya LIU, Zhiqing SHEN, Xiangyan WU, Nanhui XU, Jianfeng CHU, Youqin CHEN, Jun PENG

“…Then the cells were collected by digestion and centrifugation after treating with different concentrations (0,10,20, and 40 μmol/L) of BA for 48 h.1.0×10⁵cells/mL cell suspension was used for the Transwell experiment of cell migration and invasion, respectively. …”
Get full text

Integrating Bulk and Single-Cell Transcriptomic Data to Identify Ferroptosis-Associated Inflammatory Gene in Alzheimer&rsquo;s Disease by Zhou H, Peng Y, Huo X, Li B, Liu H, Wang J, Zhang G

“…This subpopulation simultaneously expressed characteristic markers of peripheral blood monocytes, suggesting that these cells may originate from peripheral blood monocytes, thereby triggering neuroinflammation through the ferroptosis pathway. Cell experiments confirmed that SLC11A1 was significantly upregulated in inflammatory microglia induced by ferroptosis.Conclusion: This study reveals the key role of SLC11A1 in AD, particularly in the context of ferroptosis and immune inflammation. …”
Get full text

Construction and characterization of chimeric FcγR T cells for universal T cell therapy by Juanjuan Zhao, Manling Chen, Xudong Li, Zhaoqi Chen, Wei Li, Rongqun Guo, Min Wang, Zhongxing Jiang, Yongping Song, Jianxiang Wang, Delong Liu

“…The functionality of CFR T cells was evaluated through degranulation assays, specific target lysis experiments, in vitro cytokine production analysis, and assessment of tumor xenograft destruction specificity in mouse models using different monoclonal antibodies (MoAbs). …”
Get full text

THE ROLE OF N. I. VAVILOV AND VIR’S SCIENTISTS IN DESERT RECLAMATION by N. I. Dzyubenko, A. A. Kochegina

“…They were the first in the world to suggest using phytomelioration by psammophytes of moving sands, conducted successful experiments in the introduction of black saxaul, calligonum and sandy acacia into cultivation and discovered the wet condensation subsurface horizon creating reserves of moisture in the sand dunes. …”
Get full text

Upregulated SAE1 Drives Tumorigenesis and Is Associated with Poor Clinical Outcomes in Breast Cancer by Hong Liu, Jing Wang, Yunhai Li, Feng Luo, Lei Xing

“…Through bioinformatics analysis and in vitro experiments, the biological function and possibly associated signal pathways of SAE1 in BC were further analyzed. …”
Get full text

MT2A promotes angiogenesis in chronically ischemic brains through a copper–mitochondria regulatory mechanism by Ni Mo, Chuyang Tai, Yang Yang, Cong Ling, Baoyu Zhang, Lei Wei, Cian Yao, Hui Wang, Chuan Chen

“…The optimal drug concentration for inducing CPO was subsequently determined, and in vitro experiments revealed that HUVEC activity was significantly decreased in the CPO group under hypoxic culture, accompanied by increased DLAT oligomerization, decreased SDHB expression, increased HSP70 expression. …”
Get full text

Les paysages mémoriels de la Grande Guerre (1914-1918) : un changement de paradigme dans la recherche sur le tourisme de mémoire by Myriam Jansen-Verbeke, Wanda George

“…L’inclusion dans l’enquête de questions ouvertes portant sur les valeurs, expériences ou souvenirs de plus de 2.400 répondants provenant de 61 pays ont permis d’établir une vaste base de données, d’où se dégagent des variables pertinentes dans le processus actuel de mise en tourisme d’anciens paysages mémoriels. …”
Get full text

Relationship between chlorophyll-a, sea surface temperature, and sea surface salinity by M. Hidayat, R. Wafdan, M. Ramli, Z. Muchlisin, S. Rizal

“…It was carried out in the Northern Bay of Bengal, which experiences extreme monsoons, in the southwest monsoon and northeast monsoon from June to September and November to February, respectively. …”
Get full text

A novel human specific lncRNA MEK6-AS1 regulates adipogenesis and fatty acid biosynthesis by stabilizing MEK6 mRNA by Di Li, Yunhua Chen, Xingyu Zhu, Yanlei Yang, Hongling Li, Robert Chunhua Zhao

“…Loss- and gain-of function experiments in vivo and in vitro were used to analyze effects of lncRNA. …”
Get full text

Masculinization of Nile tilapia (Oreochromis niloticus) by administration of bull testes meal by Muslim Muslim, M. Zairin Junior, Nur Bambang Priyo Utomo

“…Experimental design was utilized two factors experiments in completely randomized design. Fry kept in 40-L glass aquaria at a density of 40 fry/aquarium. …”
Get full text

Reduced Circulating Levels of miR-491-5p and miR-485-3p Are Associated with the Occurrence of Vertebral Fractures in Postmenopausal Women with Osteoporosis by Jixi Xu, Mingbo Li, Wei Pei, Jinyong Ding, Yueran Pan, Huifeng Peng, Shiman Lin, Yanbo Huang

“…Postmenopausal women experiences osteoporotic structural damage and bone fragility resulting from reduced bone formation and increased bone resorption. …”
Get full text

Prediksi Produksi Biofarmaka Menggunakan Model Fuzzy Time Series dengan Pendekatan Percentage Change dan Frequency Based Partition by Dwi Ekasari Harmadji, Solikhin Solikhin, Uky Yudatama, Agus Purwanto

“…Thus, competent parties can use the outcomes of this experiment to help determine future strategic policies. …”
Get full text

Chemical composition and insecticidal potential of botanical fractionation extracts for the management of Sitophilus zeamais Motschulsky, 1855 (Coleoptera: Curculionidae) in stored... by Fikadu Kifle, Melaku Girma, Araya Gebresilassie, Yitbarek Woldehawariat, Estifanos Ele

“…Fractionated extracts were obtained by macerating and soaking E. globulus leaves, whole T. minuta plants and A. squmosa seeds using hexane, chloroform, and methanol as extraction solvents. Experiment tests were carried out at different doses (5, 10, and 15 g/kg) on adult S. zeamais to investigate adult mortality rate, progeny inhibition rate, repellent effect, fumigation effects, and effects on grain weight loss. …”
Get full text