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34601
Biotechnological Effects of <i>Lactobacillus plantarum</i>, Cellulase, and Xylanase on Nutritional Quality and Microbial Community Structure of Corn Stover Silage
Published 2025-01-01“…Furthermore, dosage gradients were established to determine the optimal dosage range, providing a robust scientific basis for the optimization of additive applications. In this experiment, corn stover was used as the substrate, with the moisture content maintained at 60%. …”
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34602
B7-H3 CAR-T cell therapy combined with irradiation is effective in targeting bulk and radiation-resistant chordoma cancer cells
Published 2025-01-01“…An irradiator was used for all irradiation (IR) experiments.Results The combination of B7-H3 CAR-T cell therapy and IR has a greater killing effect on killing radiation-resistant CCSCs and bulk chordoma cells compared with CAR-T cell or IR monotherapy. …”
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34603
Antifungal activity and mechanism of Phoebe bournei wood essential oil against two dermatophytes
Published 2025-02-01“…Fluorescence microscopy images showed excessive production of ROS and disruption of MMP in dermatophytes after PWEO treatment. Physiological experiment of M. gypseum showed significant differences in protein extravasation, extracellular conductivity and intracellular MDA content after three hours of treatment with 0.450 mg/mL PWEO compared with the control. …”
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34604
Sonic hedgehog restrains the ubiquitin-dependent degradation of SP1 to inhibit neuronal/glial senescence associated phenotypes in chemotherapy-induced peripheral neuropathy via the...
Published 2025-02-01“…Furthermore, our in vivo experiments demonstrated that Shh activation significantly reduced axonal degeneration, demyelination, and improved nerve conduction. …”
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34605
Strategies adopted by men to deal with uncertainty and anxiety when following an active surveillance/monitoring protocol for localised prostate cancer and implications for care: a...
Published 2020-09-01“…Only men from ProtecT were included; men outside ProtecT may have different experiences.Conclusion Men looked to clinicians for clarity, control and reassurance. …”
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34606
The antiarthritic effect of CBR‐470‐1 in hypoxic environment is to increase the level of NOD‐like receptor family pyrin domain containing 3 ubiquitination by decreasing phosphoglyc...
Published 2025-01-01“…Conclusions This study conducted a series of in vitro and in vivo experiments, revealing that hypoxia plays a pro‐inflammatory role by increasing PGK1 activity and reducing the binding of the deubiquitinating enzyme ubiquitin‐specific peptidase 14 to NLRP3, thereby reducing the ubiquitination level of NLRP3. …”
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34607
How Uremic Toxins Alter Atorvastatin Disposition: Molecular Mechanisms of Inhibition of the Enzyme CYP3A4
Published 2025-01-01“…RLM were extracted, and the metabolic experiment of ATV was performed in a human CYP3A4 model. …”
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34608
Potential impact and mechanism of aged polyethylene microplastics on nitrogen assimilation of Lactuca sativa L.
Published 2025-02-01“…In this study, pot experiments were conducted to investigate the potential effect of aged polyethylene (PE) microplastic addition (particle sizes: 20 and 0.1 µm, addition levels: 0.5 % [w/w], referred to as the control (CK), P20 (20-µm PE), AP20 (20-µm aged PE), P0.1 (0.1-µm PE), AP0.1 (0.1-µm aged PE) on MNPs accumulation and N assimilation in romaine lettuce (Lactuca sativa L.). …”
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34609
Large-scale production of Mansonella perstans infective larvae from engorged Culicoides milnei
Published 2024-12-01“…Previous studies have developed in vitro culture systems using infective stage 3 larvae (L3), but these life stages are difficult to obtain and thus the performance of in vitro cultures is restricted and does not allow large-scale testing of drugs or even infection experiments in animal models. Therefore, we aim to establish a platform for the large-scale production of M. perstans infective larvae from engorged Culicoides milnei.MethodsCulicoides species were caught in Yangom (Yabassi Health District) in the Littoral Region of Cameroon following a blood meal on six microfilariae-positive donors with different microfilaraemic loads over one year. …”
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34610
Lycium barbarum polysaccharide inhibits retinal neovascularization and inflammation in vitro and in vivo
Published 2025-02-01“…METHODS: In vitro tests were performed on human retinal microvascular endothelial cells (HRECs) from three groups, including control group (normal oxygen), hypoxic group (hypoxia at 37℃, 1% O2, 5% CO2, and 94% N2), and LBP group (hypoxic group with LBP 100 μg/mL). In vivo experiments, C57 mice were divided into three groups: control group (normal rearing group), the oxygen-induced ischemic retinopathy (OIR) group, and the OIR with 50 mg/kg LBP group. …”
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34611
Integrating Two-Tier Optimization Algorithm With Convolutional Bi-LSTM Model for Robust Anomaly Detection in Autonomous Vehicles
Published 2025-01-01“…To demonstrate the optimum classification outcome of the IWOAFS-XAIAD technique, a wide range of experiments is performed on a VeReMi dataset. The experimental validation of the IWOAFS-XAIAD technique portrayed a superior accuracy value of 98.52% over the existing methods.…”
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34612
A clinical study of the immunogenicity and protective potency of a live recombinant GamLPV vaccine for intranasal use for the prevention of whooping cough in adult volunteers
Published 2024-12-01“…A new live recombinant pertussis vaccine for intranasal use (GamLPV) has completed preclinical studies in experiments on nonhuman primates and 2 phases of clinical trials involving adult healthy volunteers, in which the safety, immunogenicity and protective activity of the GamLPV were proven. …”
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34613
Evaluation of eco-driving performance of electric vehicles using driving behavior-enabled graph spectrums: A naturalistic driving study in China
Published 2025-02-01“…Firstly, a multi-source refined data set was constructed through naturalistic driving experiments (NDE). Four typical traffic state (CCCF: congested close car-following; CSSF: constrained slow free-flow; CSCF: constrained slow car-following; UFFF: unconstrained fast free-flow) were classified through longitudinal acceleration data, and driving behavior graph was constructed to realize the visual representation of driving behavior. …”
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34614
Perancangan Knowledge Sharing System Untuk Meningkatkan Kinerja Dosen Di Fakultas Teknik Universitas Bangka Belitung
Published 2023-07-01“…However, adaptation will be difficult when colleagues and seniors do not provide discussion space to share information, knowledge and experiences with new lecturers. With the plan to open a new study program at the Faculty of Engineering, Universitas Bangka Belitung (UBB), new lecturers have to be in a temporary homebase that is not their scientific field. …”
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34615
K-Pop Fandom Activism on Social Media: Refuting Accusations of Slacktivism in Internet Activism
Published 2024-11-01“…Therefore, future research should integrate the views and experiences of those directly involved in K-Pop fandom activism so that it is possible to formulate more comprehensive conclusions. …”
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34616
Different starch sources and amino acid levels on growth performance, starch and amino acids digestion, absorption and metabolism of 0- to 3-week-old broilers fed low protein diet
Published 2025-03-01“…The study aimed to investigate how the starch digestion rate and amino acid levels impact the growth and intestinal starch and amino acid digestion, transport, and metabolism in juvenile broilers. The experiment was conducted with 702 Arbor Acres Plus broilers at 1 d old, which were randomly divided into 9 treatments with 6 replicates of 13 chickens each. …”
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34617
NH3 release during the snow evaporation process in typical cities in Northeast China
Published 2025-01-01“…This study collected snow samples from five notable snowfall events in Changchun, Jilin Province that occurred from November 2023 to March 2024, to conduct indoor simulated evaporation experiments (among them, the actual phase changes of two snowfall events consisted mainly of evaporation, whereas those of the other three events consisted mainly of sublimation). …”
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34618
Genetic predisposition to Behcet's disease mediated by a IL10RA enhancer polymorphism
Published 2025-01-01“…Methods: To analyse the genetic susceptibility to BD mediated by IL10RA causal polymorphisms, we performed a study on data from our previous genome-wide association studies (GWAS), the bioinformatic analysis of post-annotation of GWAS and relevant mechanism verification experiments, including chromatin immunoprecipitation, luciferase gene-reporter assay, electrophoretic mobility shift assays, and enzyme-linked immunosorbent assay. …”
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34619
Enterobacter-inoculation altered the C, N contents and regulated biomass allocation in Reaumuria soongorica to promote plant growth and improve salt stress tolerance
Published 2025-01-01“…This study explores the impact of PGPR on biomass allocation, C, and N contents of R. soongorica seedlings through a pot experiment. Strains P6, N20, and N21, identified as Enterobacter, were isolated from the rhizosphere of R. soongorica, and they exhibited various beneficial traits such as indole-3-acetic acid (IAA) production, phosphate solubilization, nitrogen fixation, and tolerance to up to 8% NaCl stress. …”
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34620
Pengaruh Paparan Medan Magnet Extremely Low Frequency (ELF) terhadap Perubahan pH Pada Proses Fermentasi Biji Kopi Lanang (Peaberry) Kering
Published 2021-09-01“…The type of research that use in the experimental reseacrh with a randomized subject post test only control grup design, it aiming to examine the effect of treatment by repeating the experiment. This study include seven sample groups covering the control group and the experimental group variation in the intensity of ELF magnetic field with 200 µT and 300 µT and variation of a length 30, 60, 90 minutes. …”
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