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33841
<i>In vitro</i> and <i>in vivo</i> tropism and biodistribution of recombinant simian adenovirus type 25
Published 2024-11-01“…At the same time, a higher tropism to human glioblastoma cells (GL-6) was found compared to the other two studied adenoviruses. In vivo experiments have shown that recombinant adenoviruses are mainly localized at the injection site, and transgene expression persists for 21 days. …”
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33842
The efficacy of Artichoke leaf extract conjugated with organic zinc nanoparticles on growth, carcass traits and blood biochemical parameters of broilers
Published 2025-01-01“…In a completely randomized design experiment, 210 1-day-old chicks (Arbor Acres) were assigned to three trial groups. …”
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33843
High interstitial fluid pressure enhances USP1-dependent KIF11 protein stability to promote hepatocellular carcinoma progression
Published 2025-01-01“…Methods This study investigates the role of kinesin family member 11 (KIF11) in HCC under HIFP conditions, using both in vivo and in vitro models. In vitro experiments replicated the HIFP environment to observe changes in HCC cell behavior and protein expression, while in vivo studies involved mice portal hypertension to create an orthotopic liver cancer model, allowing for the evaluation of tumor progression. …”
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33844
The structural characteristics of dietary fibers from Tremella fuciformis and their hypolipidemic effects in mice
Published 2023-03-01“…The results showed tremella dietary fibers were significant in swelling, water holding and oil holding, cholesterol and bile acids. In vivo experiment results in mice indicated that SDF has the best effect on hyperlipidemia mice than IDF and total dietary fiber (TDF). …”
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33845
MP-LLAVRec: an agricultural product recommendation algorithm based on LLAVA and user modal preference
Published 2025-01-01“…It consisted of three main components: (1) LLAVA data enhancement, which introduced a multimodal macromodel to improve the understanding of node attributes; (2) agricultural product association relationship fusion, which constructed and improved the complex association network structure among products to ensure that the system can better understand the substitution relationship, complementary relationship, and implied consumption logic among products; (3) user modal preference feature extraction block, which deeply mined the interaction data between consumers and products, and advanced the effective user feature information from the correspondence between global user representations and local modal user representations.Results and DiscussionWe conduct experiments on a real dataset from Amazon's large-scale e-commerce platform to verify the effectiveness of MP-LLAVRec. …”
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33846
Drought Adaptation and Responses of Stipa krylovii Vary Among Different Regions: Evidence From Growth, Physiology, and RNA‐Seq Transcriptome Analysis
Published 2025-01-01“…In this study, to explore the drought adaptation and responses of the dominant species in the semi‐arid Eurasian Steppes and their differences among the different regions in terms of growth, physiology, and RNA‐seq transcriptome, Stipa krylovii was chosen as the study material, and a seed source (three regions: eastern, middle, and western regions) × soil moisture treatment (three treatments: control, light drought, and heavy drought) two‐factor experiment was conducted. (1) Four growth traits for individuals from the western region were significantly lower than those from the other two regions. …”
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33847
Development of a Multi-Sensor Mobile Device for Urban Air Quality Monitoring at the Street Corner: The SMILE Project
Published 2025-01-01“…The AQM device ensures reliable operation across temperature variations from 10°C to 40°C and humidity levels ranging from 10% to 70%. Outdoor experiments were conducted in the city of Marseille to validate the efficiency of the AQM device and assess its ability to provide street-level air quality data. …”
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33848
Macrofaunal biopores: Diversity and regeneration rates across diverse pedoclimatic conditions studied with repacked soil cores
Published 2025-02-01“…To capture their contribution to biopore formation, improvements of the repacked soil core approach and complementary laboratory experiments were suggested.…”
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33849
RETRACTED ARTICLE: A prospective diagnostic model for breast cancer utilizing machine learning to examine the molecular immune infiltrate in HSPB6
Published 2024-10-01“…Furthermore, in vitro cell experiments have demonstrated the impact of HSPB6 on cell migration, proliferation, and apoptosis. …”
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33850
Brain penetration of peripheral extracellular vesicles from Alzheimer's patients and induction of microglia activation
Published 2025-01-01“…We demonstrated that pEVs traverse the BBB by transcytosis and subsequently diffuse progressively into the brain. pEVs were then internalized by neuronal and radial glial cells as seen in Tg(huc:EGFP) and Tg(gfap:EGFP) zebrafish, respectively. Additional experiments were performed with the intrahippocampal injection of pEVs in the mouse, indicating their spreading throughout the brain and their uptake by neuronal and glial cells. …”
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33851
A comparative machine learning study of schizophrenia biomarkers derived from functional connectivity
Published 2025-01-01“…We developed a pipeline which allows us to aggregate over a million different features and assess their predictive potential in a single, computationally efficient experiment. We selected top 1% of features with the largest permutation feature importance and trained 13 classifiers on them using 10-fold cross-validation. …”
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33852
Impact of #PCOSweightloss: A global X hashtag analysis study of weight loss narratives in the PCOS community
Published 2025-01-01“…The hashtag #PCOSweightloss has become a pivotal forum on the platform X, where individuals exchange experiences, share information, and motivate each other concerning weight loss strategies connected with Polycystic Ovary Syndrome (PCOS). …”
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33853
Curcumin nanocrystals ameliorate ferroptosis of diabetic nephropathy through glutathione peroxidase 4
Published 2025-01-01“…Furthermore, in vivo experiments were carried out to investigate the roles of Cur-NCs in STZ-induced DN rats.ResultsThe results showed that HG treatment greatly enhanced the levels of LDH, MDA, Iron, lipid ROS, apoptosis, NCOA4, TFR-1, while decreasing the expression of GSH, GPX4, SLC7A11, and FTH-1. …”
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33854
Adhesion-induced MoS2 layer transfer via in-situ TEM-nanoindentation: Effects of curvature and substrate mediated residual stress
Published 2025-01-01“…Our pioneering in situ experiments, utilizing TEM-based nanoindentation, provided precise imaging and force monitoring of MoS2's interaction with a diamond. …”
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33855
Differences in the Quality Components of Wuyi Rock Tea and Huizhou Rock Tea
Published 2024-12-01“…The sensory evaluation showed that they each have their own characteristics, but the overall acceptability of Wuyi rock tea is ahead of Huizhou rock tea (<i>p</i> < 0.01). Biochemical experiments showed that HT was the highest in water leachables, about 43.12%; WT was the highest in tea polyphenols, about 14.91%; WR was the highest in free amino acids, about 3.38%; and the six rock teas had different health benefits. …”
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33856
The expression of apoptosis-regulating proteins Bcl-2 and Bad in liver cells of C57Bl/6 mice under light-induced functional pinealectomy and after correction with melatonin
Published 2021-06-01“…In the next series of experiments, mice with LIFP received daily intragastrically either melatonin (1 mg/kg body weight in 200 μl of distilled water) or 200 μl of water as a placebo. …”
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33857
Toward Resilient Maternal, Neonatal and Child Health Care: A Qualitative Study Involving Afghan Refugee Women in Pakistan
Published 2025-01-01“…The research focused on experiences during the initial four waves of the COVID-19 pandemic (2020-2021), utilizing a conceptual framework integrating Health Emergency Disaster Risk Management (Health-EDRM) with primary health care. …”
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33858
Identification of pyrimidine metabolism-based molecular subtypes and prognostic signature to predict immune landscape and guide clinical treatment in prostate cancer
Published 2025-12-01“…TK1 was identified and the biological functions of TK1 were determined using loss-of-function experiments. RNA sequencing was subsequently performed to determine the molecules associated with the underlying mechanisms of TK1 function.Results In total, six out of 98 PMGs simultaneously exhibited differential expression in PCa and were correlated with BCR. …”
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33859
Efficacy of natural and synthetic inhibitors in the elimination of viruses in potato (<i>Solanum tuberosum</i> L.)
Published 2024-10-01“…Natural polysaccharides – carrageenans – were observed to have a significant antiviral effect, so their use in agricultural biotechnology might be promising for new experiments. Our approach successfully eliminated viruses in two new promising potato cultivars, ‘Poseidon’ and ‘Orion’, which were included in the system of virus-free seed production. …”
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33860
Exploring the growth performance, antioxidant capacity, and metabolism of Babylonia areolata in response to yeast selenium supplementation
Published 2025-03-01“…Except control group, the experiment involved five other diets, with one containing sodium selenite (1.6 mg Se/kg diet) and three containing graded levels of yeast selenium (L-YSe (2.4 mg Se/kg diet), M-YSe (14.4 mg Se/kg diet), H-YSe (22.5 mg/kg), and one containing yeast (2 g/kg). …”
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