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33721
The Impact of Technological Factors on the Air Phase of Defrosted Fermented-Milk Desserts
Published 2023-03-01“…The dispersion of structural elements was measured using microstructural methods. The experiments included the quality parameters of mixes, as we ll as the dispersion of air phase in the frozen state and after 24 h of storage at 4 ± 2°C. …”
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33722
UPLC-MS/MS Method for Givinostat in Rat Plasma: Development, Validation, in vivo Pharmacokinetics Study and in vitro Metabolic Stability Research
Published 2025-01-01“…Finally, in vitro results showed that givinostat had a slow intrinsic clearance (CLint) value of 14.92 μL/min/mg protein with a half-life (t1/2) value of 92.87 min.Conclusion: Givinostat was rapidly absorbed and cleared slowly in vivo, and it was confirmed by in vitro experiments. This study provides a potential reference for givinostat in clinical studies.Keywords: givinostat, UPLC-MS/MS, rat plasma, pharmacokinetic study, in vitro metabolic stability…”
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33723
Validation of the COTENP Code: A Steady-State Thermal-Hydraulic Analysis Code for Nuclear Reactors with Plate Type Fuel Assemblies
Published 2018-01-01“…The latter discrepancy can be partially justified due to lack of information to adequately model the IEA-R1 experiment and CARR reactor. The results show that the COTENP code is sufficiently accurate to perform steady-state thermal-hydraulic design analyses for reactors with plate type fuel assemblies.…”
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33724
Hypoglychemic activity of Moringa oleifera extract in streptozotocin-induced diabetic rats
Published 2024-08-01“…Method: Healthy male Wistar rats (weight 200-300 g, aged 9-11 weeks) were used in the experiment. The rats were divided into five groups: normal control (healthy), negative control (diabetic without treatment), positive control (diabetic treated with 9 mg/200 g metformin), treatment 1 (diabetic treated with 400 mg/kg BW M. oleifera extract), and treatment 2 (diabetic treated with 800 mg/kg BW M.oleifera extract). …”
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33725
Targeted generative data augmentation for automatic metastases detection from free-text radiology reports
Published 2025-02-01“…We further investigate three targeted data augmentation techniques which selectively expand the original training samples, leading to comparable or superior performance compared to vanilla data augmentation, in most cases, while being substantially more computationally efficient. In our experiments, data augmentation improved the average F1-score by 2.3, 3.5, and 3.9 points for lung, liver, and adrenal glands, the organs for which we had access to expert-annotated data. …”
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33726
ROS-mediated M1 polarization-necroptosis crosstalk involved in Di-(2-ethylhexyl) phthalate-induced chicken liver injury
Published 2025-01-01“…In addition, there was increased infiltration of liver macrophages (CD68), upregulation of M1 polarization indicators (CD86, iNOS, IL-1β, TNF-α) and downregulation of M2 polarization indicators (CD163, Arg-1, IL-10, TGF-β) and appearance of necroptosis (RIPK1, RIPK3, MLKL). The vitro experiments confirmed the addition of N-acetylcysteine (NAC) inhibited M1 polarization and necroptosis. …”
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33727
Reusing of Organic Waste from Tubifex sp. Substrate in nature
Published 2007-07-01“…Rearing was performed for 50 days. During experiment chicken manure of 0.075 g/m2 was added into culture every day. …”
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33728
Efficacy of Ivermectin, Liquid Paraffin, and Carbaryl against Mange of Farmed Rabbits in Central Kenya
Published 2019-01-01“…Treatments were administered as follows: group 1 (G1) received two ivermectin injections at an interval of 14 days, group 2 (G2) was treated with a combination of carbaryl and liquid paraffin applied every other day up to the end of the experiment, group 3 (G3) was treated with liquid paraffin droplets applied daily until the lesion cleared, while group 4 (G4, infected-untreated) received distilled water applied topically on their ears and group 5 (G5, uninfected-untreated negative control) was not treated with any preparation. …”
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33729
Enhancement of Cytomegalovirus-Specific Cytokine Production after Modulation of the Costimulation in Kidney Transplant Patients
Published 2019-01-01“…BTLA antibodies, however, led only to a marginal increase of CMV-specific IFN-γ and of IL-21 production. Experiments in healthy controls could confirm the results of the kidney transplant recipients. …”
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33730
miR663 Prevents Epo Inhibition Caused by TNF-Alpha in Normoxia and Hypoxia
Published 2021-01-01“…Furthermore, mimic-miR663 transfection resulted in a lower apoptosis rate of UT-7 cells in coculture experiments. Conclusions. miR663 is involved in Epo mRNA production and that is able to prevent or reverse the inhibitory effect of TNF-α. …”
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33731
Early warning systems (EWSs) for chikungunya, dengue, malaria, yellow fever, and Zika outbreaks: What is the evidence? A scoping review.
Published 2021-09-01“…Included were studies reporting on (a) experiences with existing EWS, including implemented tools; and (b) the development or implementation of EWS in a particular setting. …”
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33732
Gender Disparities in Medical and Dental Admissions: Students' Perspectives on Barriers
Published 2025-02-01“…Thirty-two first-year female students from the 2024 batch were purposively selected for focus group discussions (FGDs) to explore their personal experiences regarding gender-specific challenges. The themes that emerged were safety concerns, transportation issues, cultural norms and social pressures, lack of female role models, and family support. …”
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33733
Sorption Characteristics and Chromatographic Separation of 90Y3+ from 90Sr2+ from Aqueous Media by Chelex-100 (Anion Ion Exchange) Packed Column
Published 2024-01-01“…Thus, in this context the sorption profiles of Y3+ and Sr2+ from aqueous solutions containing diethylenetriaminepenta acetic acid (DTPA), ethylenediaminetetra-acetic acid (EDTA), acetic acid, citric acid, or NaCl onto Chelex-100 (anion ion exchange) solid sorbent were critically studied for developing an efficient and low-cost methodology for selective separation of Y3+ from Sr2+ ions (1.0 × 10−5 M). Batch experiments displayed relative chemical extraction percentage (98 ± 5.4%) of Y3+ from aqueous acetic acid solution onto Chelex-100 (anion ion exchanger), whereas Sr2+ species showed no sorption. …”
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33734
Biochemical Composition Variation among Southern Ethiopian Arabica Coffee (Coffea arabica L.) Genotypes
Published 2022-01-01“…Therefore, a nutritional laboratory experiment was carried out at Jimma University College of Agriculture and Veterinary Medicine (JUCAVM). …”
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33735
Evaluating the Impact of Data Transformation Techniques on the Performance and Interpretability of Software Defect Prediction Models
Published 2023-01-01“…Based on our findings, we recommend that (1) considering the impact of data transformation methods on model performance and interpretability when designing SDP approaches as transformations can improve model accuracy, and potentially obscure important features, which lead to challenges in interpretation, (2) conducting comparative experiments with and without the transformations to validate the effectiveness of proposed methods which are designed to improve the prediction performance, and (3) tracking changes in the most important features before and after applying data transformation methods to ensure precise and traceable interpretability conclusions to gain insights. …”
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33736
Decomposition and nutrient release pattern of wheat (Triticum aestivum) residues under different treatments in desert field conditions of Sudan
Published 2024-02-01“…Decomposition and nutrient release pattern from wheat residue were investigated in a 12 week litter bag experiment under field condition. Litter bags contain 50 g wheat residue were buried in plots cultivated with guar and treated with following treatments: crop residue (CR), recommended fertilizer ? …”
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33737
Health profession students’ perceptions of ChatGPT in healthcare and education: insights from a mixed-methods study
Published 2025-01-01“…The qualitative data revealed three main themes: experiences with ChatGPT, its impact on the quality of healthcare, and its integration into the curriculum. …”
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33738
Experimental assessment of Acanthopagrus schlegelii biomass based on environmental DNA technology
Published 2024-12-01“…This study conducted an experiment involving the aquaculture of Acanthopagrus schlegelii to explore the release and degradation mechanisms of eDNA. …”
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33739
Assessment of fire blight resistance in apple clonal rootstocks using molecular markers
Published 2020-12-01“…Most of the studied genotypes had different combinations of markers. However, the experiments showed that forms 62-396 and 14-1 with two out of three markers (AE10-375 and CH-F7-FB1) phenotypically manifested the trait of resistance to metabolites of E. amylovora.…”
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33740
One Health preparedness and response for mosquito-borne viruses: a stakeholder- and social network-analysis in the Netherlands
Published 2025-01-01“…Interviewees not currently active in MBV policy were given the opportunity to share their experiences regarding ‘zoonotic infectious diseases’ or ‘healthy living environments’. …”
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