Human Umbilical Cord Mesenchymal Stem Cells Attenuate Ocular Hypertension-Induced Retinal Neuroinflammation via Toll-Like Receptor 4 Pathway by Shangli Ji, Jie Xiao, Jian Liu, Shibo Tang

“…In addition, via in vitro experiments, we found that the increased expression of the TLR4 signaling pathway induced by lipopolysaccharide (LPS) was markedly decreased after hUC-MSCs were cocultured with rMC-1 and BV2 cells. …”
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Synthesis ratios of Mg-Al and Zn-Al layered double hydroxides efficiency and selectivity in nitrate removal from solution by M. Mohammadi, A. Mohammadi Torkashvand, P. Biparva, M. Esfandiari

“…Mg-Al (3:1), Mg-Al (4:1), Zn-Al (4:1), and Zn-Al (3:1) LDHs, were prepared to evaluate their efficiency and selectivity towards nitrate removal from aquatic solutions. A batch experiment was done at the initial nitrate concentration of 5-1000 mg/L, pH 5 to 12, and contact time of 5-180 min. …”
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Detection method of mixed coin transaction based on CoinJoin——take the Wasabi platform as an example by Hu LI, Yunfang CHEN, Wei ZHANG

“…Designed to enhance the privacy of user transactions, mixed coin technology has created disruptions to the address clustering rules typically used for cryptocurrency regulation.Consequently, hackers have begun utilizing mixed coin technology as a tool for money laundering and fund evasion, which has raised concerns among financial regulators regarding the detection of mixed coin transactions.Currently, most detection methods for mixed coin transactions rely on data analysis and statistics, lacking a comprehensive understanding of the internal workings of these transactions.This lack of knowledge may undermine the credibility and effectiveness of detection methods due to the absence of reliable verification data.CoinJoin, a decentralized mixed coin concept, represents one approach, and commercial implementations like Wasabi have gained popularity.Drawing from the characteristics of CoinJoin and its restriction on the size of anonymous transaction sets and mixed coin amounts, a general detection method for CoinJoin mixed coin transactions was devised.Such transactions typically involved multiple inputs and outputs, with more output items than UTXOs in the input, and a high occurrence of duplicate values among the output amounts.A basic detection method for Wasabi was developed by combining the generic detection method for CoinJoin with specific features of Wasabi, as identified in related studies, to complete the detection process.A trusted validation dataset was acquired from the Wasabi platform service interface, and this dataset was analyzed to achieve two objectives.First, the alignment of rule parameters in the Wasabi base detection method was accomplished.Second, a new metric was proposed, measuring the ratio of the highest frequency of duplicate values in the output amount of transactions to the number of UTXOs in the input.This metric assessed the level of user participation in mixed coin transactions, providing a measure of user freedom.Using these two approaches, significant progress is made in the detection of mixed coin transactions.The experiments show that the recall rate of Wasabi’s basic detection method is 94.2% and the accuracy rate is 67.2%.After the analytical feedback from the credible validation dataset, the recall rate of the improved detection method reaches 100% and the accuracy rate is above 99%.The total market size of the entire CoinJoin type of mixed coin transactions was evaluated and predicted based on a common test methodology.It is concluded that the number of CoinJoin mixed coin transactions in today’s mixed coin market represents 1.9 per 1 000 of all Bitcoin transactions and 3.7 per 1 000 of the transaction value at most.…”
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The systematic analysis of genes related to butyrate metabolism suggests that CDKN3 could serve as a promising therapeutic target for lung adenocarcinoma treatment by Yanchao Luan, Chao Liang, Qingsong Han, Xueqin Zhou, Na Yang, li Zhao

“…Finally, the function of CDKN3 in LUAD was verified by in vitro experiments. Results Through a comprehensive analysis of the TCGA-LUAD dataset, 51 significant BMR-DEGs were confirmed. …”
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Investigation of 4-Nitro-N, N-diphenylaniline as a chemical tracer under high pressure high temperature reservoir conditions for enhanced oil recovery applications by Subhadip Maiti, Nishant Kumar Choudhary, Kiran R. Gore, Sandeep D. Kulkarni

“…The novel tracer was also investigated experimentally for rock adsorption by exposing it to the sandstone rock particles (150–250 μm) at 121 °C; it was demonstrated that the tracer showed minimal adsorption at the rock surface (< 1%), which was equivalent to the industry-standard tracer. A core flooding experiment was conducted using the novel tracer solution on a rock sample from the Rajasthan, India, oilfield. …”
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Designing and Optimizing Heat Storage of a Solar-Assisted Ground Source Heat Pump System in China by Yan Gao, Zhi Sun, Xinxing Lin, Chuang Wang, Zongyu Sun, Yanhong Chen

“…A ground source heat pump (GSHP) project was established using the transient system simulation program (TRNSYS) based on a ground heat exchange theoretical model, which was validated by a previously established experiment in Beijing. The Beijing, Harbin, and Zhengzhou regions were used in numerical simulations to represent three typical cities where buildings require space heating (a cold region, a severe cold region, and a hot summer and cold winter region, respectively). …”
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Features of the use of physical exercises at the long-term stage of rehabilitation after intra-articular fractures by Sviatoslava Pashkevych, Tetiana Shutieieva, Оlha Beziazychna

“…All patients gave their informed consent to participate in the experiment and to the processing of their personal data. …”
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Integrating whole-genome re-sequencing and transcriptome data to reveal the molecular mechanism of TBX5 gene regulating feathered feet in Guangxi native chickens by Zhuliang Yang, Yongcui Liu, Jintang Luo, Cong Xiao, Hong Yuan, Wenya Du, Xiurong Yang

“…This study combined whole-genome re-sequencing (WGS) data, transcriptomic analysis, and cellular experiments to investigate the genetic basis of feathered feet in Guangxi native chickens. …”
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Experimental paradigm to test the effects of providing social support: study protocol of the PROSPECT trial (Study 2) by Vivien Hajak, Simone Grimm, Ewa Gruszczyńska, Aleksandra Kroemeke, Natalia Józefacka, Lisa Marie Warner

“…Discussion In a controlled laboratory experiment, this new experimental paradigm manipulates the conditions under which social support is provided. …”
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Development of a non-invasive heart rate measurement method for sea turtles with dense keratinous scutes through effective electrode placement by Ayaka Saito, Kino Sakai, Megumi Kawai, Lyu Lyu, Kazunari Kameda, Hiromi Kudo, Katsufumi Sato, Kentaro Q. Sakamoto

“…Furthermore, in the water tank experiments, continuous ECG signals were successfully recorded by attaching a negative electrode near the neck: almost noiseless clear ECG signals even during moving in seven out of ten individuals and slightly weak and noisy signals in other individuals. …”
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Using Peer-Learning and Game-Based Instruction for Achieving Long-Lasting Knowledge of Cybersecurity in Primary Schools by Maja Videnovik, Vladimir Trajkovik, Tone Vold, Linda Vibeke Kionig, Ana Madevska Bogdanova, Sonja Filiposka

“…Upper-grade students deliver lectures and create educational games for their lower-grade peers, fostering learning communities where students share their knowledge and experiences, and learn from one another&#x2019;s diverse perspectives. …”
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Citrullinated IGF2BP1 promotes rheumatoid synovial aggression via increasing the mRNA stability of SEMA3D by Yang Qin, Li Liu, Yanwen Zhang, Xiaowei Chen, Jiani Zhang, Sunwang Ling, Jianguang Wang, Xinyu Yang

“…Transcriptomic sequencing and functional verification show that citrullination at the R167 site of IGF2BP1 promotes the proliferation, migration, and invasion of RA fibroblast-like synoviocytes (RA-FLSs) by improving the mRNA stability of Semaphorin 3D (SEMA3D). Experiments in collagen-induced arthritis (CIA) mice, the classical animal model of RA, show that IGF2BP1 R176K point mutation (Igf2bp1 R167K/R167K) mice exert reduced inflammatory response, clinical scores, and joint destruction. …”
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Optimal irrigation and nitrogen fertilization for growth and yield of perennial ryegrass (Lolium perenne) by DUAN Kelong, NIU Zuirong, ZHANG Zhenrong, SONG Shuzhen, LI Miaoqi, GUO Sheng

“…[Method] The field experiment consisted of two irrigation treatments by keeping the soil water content above 75%-85% (W1) or 55%-65% (W2) of the field capacity. …”
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Water–saving irrigation combined with N–loaded clinoptilolite enhances nutrient yield, and water productivity by improving rice root characteristics: A combined PCA–SEM analysis... by Yang Sun, Qi Wu, Daocai Chi, Hongyang Chen, Suyun Zhu, Qingliang Liu

“…This two–year split–plot experiment evaluated the impact of two irrigation regimes (ICF: continuous flooding irrigation; IAWD: alternate wet–dry irrigation) and two rates of N–loaded clinoptilolite (NZ0: no N–loaded clinoptilolite; NZ10: 10 t·ha–1) on root characteristics, mineralized N, nutrient yield, and water productivity. …”
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Heterogeneity in Fluorescence-Stained Sperm Membrane Patterns and Their Dynamic Changes Towards Fertilization in Mice by Momoka Hirai, Satoshi Kishigami

“…Staining was performed either before, during, or after incubation for capacitation. In pre-staining experiments, sperm were stained with MG-560 before capacitation and then incubated to induce capacitation. …”
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Heterosis and heritability of traits contributing to select high yielding drought stress tolerance sweetpotato breeding lines by Mahaman Mourtala Issa Zakari, Emeka Benjamin Utobo, Zangui Souley Moussa, Josefina Ndamononghenda Abed, Ifeanyi Maxwell Nwankwo Innocent, Happiness Ogba Oselebe

“…The objective of this study was to estimate the heterosis and heritability of traits that contribute to drought stress tolerance and storage root yield in sweetpotatoes. Experiments were conducted at six locations in Niger (Kollo, Kalapate, Bengou, and Bangui) and Nigeria (Abakaliki and Umudike). …”
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Profesjonspraksis i møte med barnehagebarns fysiske aktivitet by Kathrine Bjørgen, Anne Holla Sivertsen, Karin Kippe

“…This study aimed to explore ECEC teachers’ experiences with professional practice related to physical activity. …”
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Finite Element Analysis of Horizontal Bearing Capacity for the Composite Diaphragm Wall Anchor Foundation by Qian Yin, Leyong Wei, Xiaojuan Li, Weiming Gong, Xueying Yang, Guoliang Dai, Shunkai Peng

“…The results reveal that under external loads, the CDWAF experiences both rigid-body translation and rotational displacement, with the rotation center shifting dynamically to the upper right with the increase in load. …”
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Personal and behavioural factors that influence physical activity in women living with metastatic breast cancer: a qualitative interview study by Mark Liu, Sharon Kilbreath, Jasmine Yee, Jane Beith, Justin McNab, Elizabeth Dylke

“…Conclusions Participants expressed diverse experiences with physical activity, with common notions on how physical activity is beneficial but difficult in which to adhere. …”
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Sexual and Gender Minority Adolescents’ Preferences for HIV Pre-Exposure Prophylaxis Social Marketing Campaigns: Qualitative Preimplementation Study by Kathryn Macapagal, Juan Pablo Zapata, Junye Ma, Jacob D Gordon, Christopher Owens, Silvia Valadez-Tapia, Peter Cummings, Nathan Walter, Jim Pickett

“…For product and price, SGM adolescents wanted a campaign to address barriers to, costs of, and how to access PrEP and desired to know about other adolescents’ PrEP experiences to improve campaign relatability. For place and promotion, participants preferred digital campaigns on social media to reduce the possibility of embarrassment and stigma and increase the accessibility of health content. …”
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