RETRACTED ARTICLE: Effect of Oroxylum indicum on hepatocellular carcinoma via the P53 and VEGF pathways based on microfluidic chips by Xi Luo, Miao Zhao, Sicong Liu, Yi Zheng, Qiang Zhang, Yong-rui Bao, Shuai Wang, Tian-jiao Li, Xian-sheng Meng

“…According to the P53 and VEGF pathways predicted by network pharmacology, RT‒qPCR and immunofluorescence staining experiments were conducted. Results The results showed that OI upregulated the expression of Bax, P53 and Caspase-3 and downregulated the expression of Bcl-2 and MDM2. …”
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An Empirical Analysis of Transformer-Based and Convolutional Neural Network Approaches for Early Detection and Diagnosis of Cancer Using Multimodal Imaging and Genomic Data by S. K. B. Sangeetha, Sandeep Kumar Mathivanan, V. Muthukumaran, Jaehyuk Cho, and Sathishkumar Veerappampalayam Easwaramoorthy

“…In search of the optimal neural network configuration, a series of experiments were conducted with respect to different layers, attention mechanisms in case of transformers, and convolutional architectures in case of CNNs. …”
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Assessing CNN and Semantic Segmentation Models for Coarse Resolution Satellite Image Classification in Subcontinental Scale Land Cover Mapping by Tesfaye Adugna, Wenbo Xu, Jinlong Fan, Haitao Jia, Xin Luo

“…We conducted several experiments to optimize models and select the best models. …”
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Identification of critical biomarkers and immune landscape patterns in glioma based on multi-database by Hanzhang Yuan, Jingsheng Cheng, Jun Xia, Zeng Yang, Lixin Xu

“…Immune staining in glioma patient samples and cell experiments of potential biomarkers further verified their expression and function. …”
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Pharmacological Mechanism of Zuojin Pill for Gastroesophageal Reflux Disease: A Network Pharmacology Study by Mi Lv, Jinke Huang, Jiayan Hu, Wenxi Yu, Ping Liu, Kunli Zhang, Fengyun Wang

“…However, whether the effect of this modulation of ROS metabolism is positive or negative needs to be further verified by pharmacological experiments.…”
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The Restoration Effect of Degraded Grassland Depends on the Response of Species Root Distribution to Resource Availability by Yiming Zhao, Hui Li, Fei Peng, Dabu Xilatu, Qing Chen, Shan Lin

“…The purpose of this study is to explore a method to distinguish the response of various plant root architectures to the resource availability in a mixed ecosystem in situ. Field experiments were conducted using isotope techniques in conjunction with a specialized experimental design at a semiarid grassland location featuring heavily grazed (HG) and moderately grazed (MG) grassland sites with different dominant species. …”
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Effects of Elemental Mercury Vapor Inhalation on Arterial Blood Gases, Lung Histology, and Interleukin-1 Expression in Pulmonary Tissues of Rats by Liqaa A. Raffee, Khaled Z. Alawneh, Ruba A. Alassaf, Abdallah Alzoubi, Musa A. Alshehabat, Nadeem Alabdallah, Abdel-Hameed Al-Mistarehi

“…In the LTG, six out of 14 (43%) rats died, including two males and four females, while none of the rats in the STG died during the experiment. In both STG and LTG, a significant acid-base imbalance was characterized by a significant decrease in blood pH values and a significant increase in PCO2 values. …”
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Ferroelectric Transistor-Based Synaptic Crossbar Arrays: The Impact of Ferroelectric Thickness and Device-Circuit Interactions by Chunguang Wang, Sumeet Kumar Gupta

“…First, based on a physics-based model of multidomain FeFETs calibrated to experiments, we analyze the impact of <inline-formula> <tex-math notation="LaTeX">$T_{\text {FE}}$ </tex-math></inline-formula> on the characteristics of FeFETs as synaptic devices, highlighting the connections between the multidomain physics and the synaptic attributes. …”
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Bioinspired activation strategies for Peano-HASEL artificial muscle. by Zhaozhen Liu, Harrison McAleese, Andrew Weightman, Glen Cooper

“…Future work should focus on more complex artificial muscle arrangements and test activation strategies in practical experiments.…”
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Metformin enhances epithelial cell growth inhibition via the protein kinase–insulin-like growth factor binding protein-1 pathway by Xuping Shao, Changling Li, Junhui Liang, Li Changzhong

“…Ten patients with ovarian-type endometriosis and eight patients each who underwent surgical treatment for other lesions with or without endometriosis were selected, and their tissues taken for cell proliferation, western blotting, polymerase chain reaction, and knockdown experiments.Results Ectopic and eutopic stromal cells (EcSCs and EuSCs) lost their ability to inhibit epithelial cell proliferation, and IGFBP1 expression was downregulated in both groups of stromal cells compared to that in normal stromal cells (NSCs; 1.09 vs. 0.25, p = .0002 1.09 vs. 0.57, p = .0029). …”
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Jiangzhi Granule Ameliorates JNK-Mediated Mitochondrial Dysfunction to Reduce Lipotoxic Liver Injury in NASH by Jiang Y, Xu J, Ding J, Liu T, Liu Y, Huang P, Wang Q, Zheng P, Song H, Yang L

“…Yuwei Jiang,1,&ast; Jiaoya Xu,1,2,&ast; Junyao Ding,1,&ast; Tao Liu,1 Yang Liu,1,3 Ping Huang,1 Qianlei Wang,1 Peiyong Zheng,1 Haiyan Song,1 Lili Yang1 1Institute of Digestive Diseases, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, People’s Republic of China; 2Department of Gout, Guanghua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, People’s Republic of China; 3Teaching Experiment Center, Shanghai University of Traditional Chinese Medicine, Shanghai, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Haiyan Song; Lili Yang, Institute of Digestive Diseases, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, 725 South Wanping Road, Shanghai, 200032, People’s Republic of China, Email songhy@126.com; yanglili76@126.comPurpose: Mitochondrial dysfunction mediated by c-Jun N-terminal kinase (JNK) plays an important role in lipotoxic liver injury in nonalcoholic steatohepatitis (NASH). …”
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«Talgenism» in the Digital Age: A Domestic History of cMOOC by M. A. Babaeva, E. B. Golubev

“…The article traces the historical milestones of the development of the method of collective mutual learning in Russia and adduces the documentary evidence of experiments on the creation of a fundamentally different pedagogical system. …”
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Protocol for the development of a reporting guideline for causal and counterfactual prediction models in biomedicine by Yi Guo, Hua Xu, Fei Wang, Jie Xu, Jiang Bian, Robert Lucero, Mattia Prosperi

“…Introduction While there are guidelines for reporting on observational studies (eg, Strengthening the Reporting of Observational Studies in Epidemiology, Reporting of Studies Conducted Using Observational Routinely Collected Health Data Statement), estimation of causal effects from both observational data and randomised experiments (eg, A Guideline for Reporting Mediation Analyses of Randomised Trials and Observational Studies, Consolidated Standards of Reporting Trials, PATH) and on prediction modelling (eg, Transparent Reporting of a multivariable prediction model for Individual Prognosis or Diagnosis), none is purposely made for deriving and validating models from observational data to predict counterfactuals for individuals on one or more possible interventions, on the basis of given (or inferred) causal structures. …”
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Long Noncoding RNA HCG9 Promotes Osteosarcoma Progression through RAD51 by Acting as a ceRNA of miR-34b-3p by Lu Wang, ShuangQing Li, Lin Qi, Lin Ling

“…A nude mouse tumor formation experiment was used to evaluate osteosarcoma progression in vivo. …”
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Experimental Study on the Bending Behavior of Steel-Wood Composite Beams by Shaowei Duan, Wenzhao Zhou, Xinglong Liu, Jian Yuan, Zhifeng Wang

“…Through the three-point monotonic static grading loading of the composite beam, the deflection change, failure phenomenon, and form of the specimen during the experiment were observed. Under the circumstances, the ultimate bearing capacity of the test piece was changed to study the combined effect of larch and hot-rolled H-shaped steel. …”
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Resistance of Chitti bean genotypes of promising to two-spotted spider mite Tetranychus urticae Koch in greenhouse conditions by Sedigheh Ashtari, Behrouz Asadi, Hamid Reza Dorri

“…The present research was conducted to identify resistance levels of chitti bean genotypes to ward T. urticae. For the experiments, Type 1 bean genotypes (standing) (KS-21216, KS-21181, KS-21538, KS-21565, KS-21563, KS-21602, KS-21500, KS-21601, KS-21600, and KS-21607), Type 2 genotypes (half standing) (KS-21573, KS-21597, and KS-21606), and Type 3 genotypes (prostrate) (KS-21255 and KS-21574), along with the susceptible variety (Sadri), were cultivated in the field at the Khomein National Bean Research Station in a randomized complete block design with three replications during two successive years (2022 and 2023). …”
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Marine Shale Gas Occurrence and Its Influencing Factors: A Case Study from the Wufeng-Longmaxi Formation, Northwestern Guizhou, China by Taotao Cao, Hu Liu, Anyang Pan, Mo Deng, Qinggu Cao, Ye Yu, Yanran Huang, Zhenghui Xiao

“…Desorption gas and lost gas determined by in situ desorption test are 0.42–1.54 cm3/g and 1.9–7.14 cm3/g, respectively, and Langmuir volume (VL) from isothermal adsorption experiment is 1.63–4.78 cm3/g. Shale gas content is positively correlated with micropore volume, mesopore volume and TOC content but negatively correlated with macropore volume and clay mineral content, indicating that methane is preferentially stored in micropores (<2 nm) and mesopores (2–50 nm) related to OMs. …”
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Polystyrene nanoplastics promote colitis-associated cancer by disrupting lipid metabolism and inducing DNA damage by Shan Tian, Ruixue Li, Jiao Li, Jinhui Zou

“…Compared to the normal control group, mice in the PS-NPs group exhibited more tumor nodes and reactive oxygen species (ROS), higher expression of pan-CK and Ki-67, and more severe DNA damage. 16S rRNA sequencing revealed that exposure to PS-NPs altered the abundance of Allobaculum and Lactobacillus, whereas metabolic analysis showed that the most significant metabolites were enriched mostly in fatty acid metabolism. Experiments in LPS intervened Caco-2 cells showed that exposure to PS-NPs led to lipid peroxidation, oxidative stress, and DNA damage in Caco-2. …”
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Efficient Path Planning and Formation Control in Multi-Robot Systems: A Neural Fields and Auto-Switching Mechanism Approach by Raouf Fareh, Mohammed Baziyad, Tamer Farouk Rabie, Sofiane Khadraoui, Mohammad Habibur Rahman

“…The effectiveness of this approach is validated through experiments, demonstrating significant improvements in execution speed, path smoothness, and overall system stability compared to competitive methods, including well-known techniques such as A*, Probabilistic RoadMap (PRM), Rapidly-exploring Random Tree Star (RRT*), and also against recent optimization techniques including Grey Wolf Optimization (GWO) and Whale Optimization Algorithm (WOA).…”
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Reasons, associated factors, and attitudes toward breastfeeding mothers’ use of complementary medicine products: a study from Türkiye by Demet Deniz Bilgin, Nalan Karabayir, Hatice Bilge Çetinkaya, Aybüke Kacir, Özlem Öçal, Mine Başibüyük, Övgü Büke

“…This study aims to investigate the reasons and associated factors of CMP use among breastfeeding mothers in Turkey, alongside their attitudes and experiences. Methods A descriptive cross-sectional study was conducted using a self-administered, anonymous online survey between 17 December 2023 and 17 March 2024. …”
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