Longitudinal Metabolomics Data Analysis Informed by Mechanistic Models by Lu Li, Huub Hoefsloot, Barbara M. Bakker, David Horner, Morten A. Rasmussen, Age K. Smilde, Evrim Acar

“…<b>Results</b>: Our experiments demonstrated that the joint analysis of simulated and real data had better performance in terms of pattern discovery, achieving higher correlations with a BMI (body mass index)-related phenotype compared to the analysis of only real data in males, while in females, the performance was comparable. …”
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Effects of Soil Disinfection Using Chlorine Dioxide on Soil Fungal Communities in Apple Replant Fields and the Growth of <i>Malus hupehensis</i> Rehd. Seedlings by Gongshuai Wang, Yuxin Xie, Jinhui Lv, Susu Zhang, Chengmiao Yin, Yusong Liu, Zhiquan Mao

“…The experimental results indicated that a high concentration of 600 mg·L⁻¹ chlorine dioxide exhibited a potent lethal effect on both the hyphae and spores of pathogenic <i>Fusarium</i>. Results from pot experiments demonstrated that, compared with the replant control, the height, ground diameter, fresh weight, and dry weight of <i>Malus hupehensis</i> Rehd. seedlings treated with 600 mg·L⁻¹ chlorine dioxide increased by 27.20%, 15.95%, 100.70%, and 76.28%, respectively. …”
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Structural Characterization and Antioxidant Activity in Vivo of Polysaccharides from the Leaves of Hippophae rhamnoides L. by Niannian SONG, Yuxin YI, Xiaoping ZHANG, Bo YANG, Mangsier SAINAWAER, Abuduwaili AYITUXUN

“…The structure of HRLP-2 was identified based on the analysis of liquid chromatography, gas chromatography, UV, infrared spectroscopy, circular dichroism, Congo red experiment, as well as partial acid hydrolysis, periodate oxidation, and Smith degradation methods. …”
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Experimental Study of 2-Ethylhexyl Nitrate Effects on Engine Performance and Exhaust Emissions of Diesel Engine Fueled with Diesel–2-Methylfuran Blends by Balla M. Ahmed, Maji Luo, Hassan A. M. Elbadawi, Nasreldin M. Mahmoud, Pang-Chieh Sui

“…This study investigates the effect of adding 2-ethylhexyl nitrate (2-EHN), a cetane enhancer, to the M30 blend (30% 2-MF by volume), on combustion characteristics and exhaust emissions. Experiments were conducted using a modified four-cylinder, four-stroke, direct-injection compression ignition (DICI) engine featuring a common rail fuel injection system. …”
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An Outdoor Walking Program for Immigrant Muslim Older Adults: A Community‐Based Participatory Intervention by Jordana Salma, Shelby Yamamoto, Nancy M Salbach, Ruth Barclay, Allyson Jones

“…ABSTRACT Aim To explore Muslim immigrant older adults' experiences of a modified community‐based outdoor walking program and identify factors that facilitate or hinder program acceptance and participation. …”
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Integration of artificial intelligence and advanced optimization techniques for continuous gas lift under restricted gas supply: A case study by Leila Zeinolabedini, Forough Ameli, Abdolhossein Hemmati-Sarapardeh

“…To this end, 154 data points constructed by a central composite design (CCD) experiment were utilized to develop neural network models. …”
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Accumulation and Transport of Cd, Pb, As, and Cr in Different Maize Varieties in Southwest China by Qi Liu, Sheng Wang, Jijiang Zhou, Li Bao, Wenbing Zhou, Naiming Zhang

“…In this study, we conducted field experiments to investigate the differences in biological traits among 28 local maize varieties under combined soil pollution with Cd, Pb, As, Cr, and Hg. …”
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Network Pharmacology Combined With Metabolomics Reveals the Mechanism of Yangxuerongjin Pill Against Type 2 Diabetic Peripheral Neuropathy in Rats by Jin R, Pei H, Yue F, Zhang X, Zhang Z, Xu Y, Li J

“…Pharmaceutical factory, Beijing, 100079, People’s Republic of China, Tel +86-10-87632655, Email xy706@sina.com; yarily@126.comPurpose: This study aims to explore the mechanism of Yangxuerongjin pill (YXRJP) in the treatment of diabetic peripheral neuropathy (DPN) by network pharmacology and metabolomics technology combined with animal experiments, and to provide scientific basis for the treatment of DPN.Methods: In this study, network pharmacology analysis was applied to identify the active compounds, core targets and signal pathways, which might be responsible for the effect of DPN. …”
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Supporting self-management for patients with Interstitial Lung Diseases: Utility and acceptability of digital devices. by Malik A Althobiani, Rebecca Shuttleworth, John Conway, Jonathan Dainton, Anna Duckworth, Ana Jorge Da Ponte, Jessica Mandizha, Joseph W Lanario, Michael A Gibbons, Sarah Lines, Chris J Scotton, John R Hurst, Joanna C Porter, Anne-Marie Russell

“…We sought to quantify patients' usage and experiences with home digital devices, and further evaluate their perceived utility and barriers to adaptation.…”
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Influence of Injection Pressure on the Dual-Fuel Mode in CI Engines Fueled with Blends of Ethanol and Tamanu Biodiesel by M. Parthasarathy, P. V. Elumalai, M. Murunachippan, P. B. Senthilkumar, Saboor Shaik, Mohsen Sharifpur, Nima Khalilpoor

“…Under peak load conditions, NOx emissions of TMEE10 are 6.2% lower than those of neat TME in the CI mode. Furthermore, the experiment was conducted using TMEE10 as the primary fuel and CNG as the secondary fuel. …”
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How climate change is shaping young people’s health: a participatory, youth co-led study from Bangladesh, Guatemala and Nigeria by Jessie Pinchoff, Karen Austrian, Eno-Obong Etetim, Damilola Babatunde, Eleanor Blomstrom, Sigma Ainul, Toyin Olamide Akomolafe, Brian Medina Carranza, Angel Del Valle

“…Open-ended questions elicited responses regarding AYP knowledge, experiences and perceptions of climate change. Using NVivo software, translated transcripts were coded to explore and synthesise key thematic areas.Results Respondents discussed varied climate exposures and associated health risks, for example, how flooding events were impeding access to sexual and reproductive health commodities. …”
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Growth, Yield and Quality of Maize under Ozone and Carbon Dioxide Interaction in North West India by Achchhelal Yadav, Arti Bhatia, Sudesh Yadav, Archana Singh, Ritu Tomer, Ramesh Harit, Vinod Kumar, Bhupinder Singh

“…To understand how the growth and nutritional quality of maize will be affected under elevated carbon dioxide (CO2) and tropospheric ozone (O3) interaction, a field experiment was conducted under free air O3 and CO2 enrichment rings (FAOCE) growing HQPM-1 and PMH-1 maize cultivars at New Delhi, India. …”
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Stakeholders’ perceptions of adolescents’ sexual and reproductive health needs in Southeast Nigeria: a qualitative study by Obinna Onwujekwe, Chinyere Cecilia Okeke, Chinyere Ojiugo Mbachu, Ifunanya Clara Agu, Uchenna Ezenwaka, Ifeyinwa Arize, Chibuike Agu, Chinonso Obayi

“…A total of 77 in-depth interviews, 6 (with community leaders) and 12 (with adolescents) focus group discussions were conducted using pretested question guides.Results Adolescent SRH needs were perceived to be unique and special due to their vulnerability, fragility and predisposition to explore new experiences. Recurring adolescent SRH needs were: SRH education and counselling; access to contraceptive services and information. …”
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Assessing molecular changes underlying isopropylated phenyl phosphate (IPP)-induced larval sensorimotor response deficits in zebrafish by Sunil Sharma, Alfredo Rojas, Abhishek Gour, Rosemaria Serradimigni, Connor Leong, Abhisheak Sharma, Subham Dasgupta

“…Our initial range-finding experiments revealed significant morphological impacts like pericardial edema, yolk sac edema and spinal curvature, coupled with a significant increase in the levels of dopamine and 3-methoxytyramine. …”
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A nociceptor-specific RNAi screen in Drosophila larvae identifies RNA-binding proteins that regulate thermal nociception by Amber Dyson, Gita Gajjar, Katherine C. Hoffman, Dakota Lewis, Sara Palega, Erik Rangel Silva, James Auwn, Andrew Bellemer

“…The screen and subsequent validation experiments identified nine candidate genes (eIF2α, eIF4A, eIF4AIII, eIF4G2, mbl, SC35, snf, Larp4B and CG10445) that produce defects in nociceptive response latency when knocked down in larval nociceptors. …”
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Improving doublet cell removal efficiency through multiple algorithm runs by Yong She, Chaoye Wang, Qi Zhao

“…Overall, we proved that the MRDR strategy was more effective in removing doublets and advantageous for downstream analyses, and the strategy could be incorporated into the standard analysis pipeline for scRNA-seq experiments and recommend using cxds to remove doublets through two rounds of algorithm iteration.…”
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Effect and Mechanism of Soluble Dietary Fiber from Corn Bran on Loperamide-induced Constipation in Mice by Xiangrui ZENG, Caixia JIANG, Xiaolan LIU, Xiqun ZHENG, Xuyao WEI

“…Small bowel propulsion rate and colon pathology experiments showed a 110.58% increase in small bowel propulsion rate, and a 43.67% increase in colonic crypt depth in the combined group compared with that of the model group. …”
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Copper Resistance in <i>Pseudomonas syringae</i> pv. <i>actinidiae</i> Strains from the Prefecture of Pella, Northern Greece, and a Comparison of the Effectiveness of Several Comme... by Thomas Thomidis, Marianthi G. Pagoulatou, Eleftherios Alexandridis, Evaggelia Mpalantinaki, Dimitrios E. Goumas

“…In addition to studying copper resistance, the research evaluated the effectiveness of several products in controlling <i>Psa</i> through field experiments. The copper products IONIC CONCENTRATED COPPER, MAGNA BLUE, and COPROFIX ULTRA were tested due to their historical effectiveness in managing bacterial diseases in plants. …”
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Barriers facilitators and needs of female sex workers in Arak to access sexual health services a qualitative study by Iman Navidi, Elham Shakibazadeh, Firoozeh Raisi, Samaneh Akbarpour

“…The participants believed that peer education offers several benefits, including building credibility and trust among peers, fostering positive interactions within peer groups, enhancing support through shared experiences, improving access to educational resources and empowerment through peer education. …”
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Atomistic Insight into the Effects of Collision Angle on the Characteristics of Cu-Ta Joining by Explosive Welding by Van-Thuc Nguyen, Nguyen Quang Hien, Pham Minh Duc, Tran Duy Nam, Van Huong Hoang, Van Thanh Tien Nguyen

“…The stress evolution experiences three stages: quick increasing, spreading out, and stabling. …”
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