Obstacle Avoidance for Ship Navigation Safety Combining Heuristic Search Algorithm and Improved ACO Algorithm by Dan Wang, Yan Jing

“…Through simulation experiments and practical applications, the study verifies the capability of the obstacle avoidance planning model. …”
Get full text

Bright night sleeping environment induces diabetes and impaired glucose tolerance in non-human primates by Shuxing Wang, Zhenyi Chen, Zihao Liang, Qiang Xu, Jiankai Zhang

“…However, there is little direct experiment on primates to study the precise extent of how serious bright sleeping environment at night impairs glucose metabolism, what the relationship is between nocturnal brightness and the development of diabetes and IGT, any difference between male and female, and whether aging and weight are involved. …”
Get full text

Development of an sRNA-mediated conditional knockdown system for Chlamydia trachomatis by Janina Ehses, Kevin Wang, Asha Densi, Cuper Ramirez, Ming Tan, Christine Sütterlin

“…In proof-of-principle experiments, we induced functional knockdown of IncA, a fusion-mediating inclusion membrane protein, as shown with Western blots, loss of IncA staining at the inclusion membrane, and production of multiple chlamydial inclusions within an infected cell. …”
Get full text

Psychosocial factors influencing dietary management in patients with type 2 diabetes and healthy adults: an ecological momentary assessment approach by Junichi Saito, Hiroaki Kumano, Hiroaki Kumano

“…Ecological momentary assessment (EMA) allows patients to consistently report their experiences in real-time over a certain period and across different contexts. …”
Get full text

Combined analysis of 16S rRNA sequencing and metabolomics reveals the growth-promoting mechanism of compound probiotics in zig-zag eel (Mastacembelus armatus) by Yuwei Feng, Zhiting Zuo, Guangting Xie, Yiman Chen, Xiaoli Yin, Baoyue Lu, Zhide Yu, Chong Han, Hu Shu

“…The objective of this experiment was to investigate the effects of single or combined supplementation with marine fish probiotics on growth performance, intestinal physiology, gut microbes, and gut metabolites in zig-zag eel (Mastacembelus armatus). …”
Get full text

Pore Structure, Fractal Features, and Oil Content Evaluation of Lacustrine Shale: A Case Study of First Member of Paleogene Shahejie Formation, NE China by Enze Wang, Gang Chen, Hanqi Li, Yanchen Song, Jianwei Wang, Zhuoya Wu, Yue Feng

“…To further expand our geological understanding of lacustrine shales and provide guidance for hydrocarbon exploration, in this study, based on programmed and improved Rock-Eval pyrolysis, total organic content (TOC) measurements, scanning electron microscopy (SEM) observations, and N2 adsorption (NA) experiments, a systematic evaluation of the mineral composition, geochemical features, pore structure, and oil contents of the third member of the Paleogene Shahejie Formation (Es3) shale in the typical lacustrine hydrocarbon enrichment sag (Nanpu Sag, Bohai Bay Basin) is conducted. …”
Get full text

BMSC-Derived Exosomes Ameliorate Osteoarthritis by Inhibiting Pyroptosis of Cartilage via Delivering miR-326 Targeting HDAC3 and STAT1//NF-κB p65 to Chondrocytes by Honggang Xu, Bin Xu

“…The targeted relationship between miR-326 and HDAC3 was verified by dual-luciferase reporter assay. Animal experiments confirmed the mechanism by which miR-326 delivered by BMSC-Exos inhibits pyroptosis of cartilage by targeting HDAC3 and STAT1/NF-κB p65 signaling pathway. …”
Get full text

Multi-scale feature fusion of deep convolutional neural networks on cancerous tumor detection and classification using biomedical images by U. M. Prakash, S. Iniyan, Ashit Kumar Dutta, Shtwai Alsubai, Janjhyam Venkata Naga Ramesh, Sachi Nandan Mohanty, Khasim Vali Dudekula

“…Finally, the parameter tuning process is performed through a hybrid fireworks whale optimization algorithm (FWWOA) to enhance the classification performance of the CAE model. A wide range of experiments is performed to authorize the performance of the MFFDCNN-CTDC approach. …”
Get full text

tPA‐GFP is a reliable probe for detecting compound exocytosis in human pancreatic β‐cells by Aishwarya A. Makam, Shruti Sharma, Prajwal Nagle, Nandhini M. Sundaram, Vidya Mangala Prasad, Nikhil R. Gandasi

“…These observations, with additional experiments, may open a whole new field to study the impact of compound exocytosis on biphasic secretion of insulin. …”
Get full text

RESISTANCE TO THE BLAST AGENT AND THE MORPHOBIOLOGICALFEATURES OF GENOTYPES IN THE Oryza sativa L. COLLECTION FROM VARIOUS ECOLOGICAL AND GEOGRAPHICAL GROUPS IN CONDITIONS OF КUBAN... by T. L. Korotenko, O. A. Bragina, I. I. Suprun, Zh. M. Mukhina, Yu. V. Epifanovich, A. A. Petrukhnenko, T. А. Khorina

“…The results of the comparison of germplasm of domestic and foreign varieties according to the degree of resistance to the pathogen in conditions of natural infection in the field experiment for five years are presented. As a result of the evaluation of plant resistance to the Krasnodar population of the pathogen, the effective genes for resistance to the pathogen for breeding programs of the south of Russia and the molecular genetic analysis of the rice collection variety were determined: Pi-1, Pi-z, Pi-ta, Pi-z5, Pi-9, Pi-5(t), Pi-t, Pi-19.…”
Get full text

Optimizing in vitro spherulation cues in the fungal pathogen Coccidioides by Christina M. Homer, Elena Ochoa, Mark Voorhies, Anita Sil

“…Finally, we examined how the conditions under which arthroconidia are generated influence their transcriptome and subsequent development into spherules, demonstrating that this is an important variable to control when designing spherulation experiments. Together, our data reveal multiple strategies to optimize in vitro spherulation growth, enabling characterization of this virulence-relevant morphology.IMPORTANCECoccidioides spp. are thermally dimorphic fungal pathogens found in the Southwest United States, Mexico, Central America, and South America. …”
Get full text

Identification and characterization of Faecalibacterium prophages rich in diversity-generating retroelements by Anastasia Gulyaeva, Lei Liu, Sanzhima Garmaeva, Marloes Kruk, Rinse K. Weersma, Hermie J. M. Harmsen, Alexandra Zhernakova

“…DGRs of two phages were active at the time of the induction experiments, as evidenced by nucleotide variation in sequencing reads. …”
Get full text

Can Thinning Foster Forest Genetic Adaptation to Drought? A Demo‐Genetic Modelling Approach With Disturbance Regimes by Victor Fririon, Hendrik Davi, Sylvie Oddou‐Muratorio, Gauthier Ligot, François Lefèvre

“…We conducted a simulation experiment spanning three nonoverlapping generations with the individual‐based demo‐genetic model Luberon2. …”
Get full text

Influence of type traits on stayability in the Ital- ian Mediterranean buffalo by Damiano Altieri, Stefano Biffani, Mayra Gómez, Yuri Gombia, Dario Rossi, Luca Gubitosi, Nadia Piscopo, Francesca Carnovale, Rossella Di Palo

“… The selection schemes adopted over the past 20 years for the Italian Mediterranean Buffalo, together with the marked improvement in farm management techniques and the systematic application of AI in an increasing number of subjects, have resulted in a sharp improvement in the quantities of milk produced per lactation. Experiences from dairy cows suggest that such an improvement could reduce the average productive life span of breeding females and, therefore, their longevity. …”
Get full text

Silent struggles: a qualitative study exploring mental health challenges of undergraduate healthcare students by Shahd Al-Najdi, Abdulla Mansoor, Ola Al Hayk, Najah Al-Hashimi, Kamran Ali, Alaa Daud

“…This paper aimed to explore the experiences of undergraduate healthcare students facing mental health challenges at Qatar University. …”
Get full text

Growth Regulator Indole-3-Butyric Acid on Rooting Potential of <i>Actinidia deliciosa</i> Rootstock and <i>Actinidia arguta</i> Female Scion Species Stem Cuttings by Mapogo Kgetjepe Sekhukhune, Yvonne Mmatshelo Maila

“…Treatment comprised IBA concentrations of 0, 10, 100, 1000, 10,000 and 100,000 ppm. Parallel experiments for <i>A. deliciosa</i> and <i>A. arguta</i>’s treatment were arranged in a randomised complete block design, with 12 replications. …”
Get full text

Does Context Matter? Governance Models in Local Administration by Stefanie Vedder, Benjamin Friedländer, Simon Bogumil-Uçan, Tanja Klenk

“… Purpose: Over the past decades, public administration scholars and practitioners around the world have experimented with various administrative reforms to design governance models suitable to fulfil the tasks of public administration. …”
Get full text

Multi-criteria decision-making method for emergency shelter site selection considering flood risk: A case study of Zhuhai, China by Bo Liu, Yingbing Li, Yan Zhang, Zhichao Wu, Yansong Pan, Meiquan Li

“…In addition, the coverage rate of the selected locations in this study significantly increased by 55.3%, which exceeded the results of all comparative experiments established in this study. Among the 11 indicators involved in decision making, the most sensitive to the site selection results were slope and impervious surface, and the least sensitive was fire station accessibility. …”
Get full text

Integrative analysis of 5-methylcytosine associated signature in papillary thyroid cancer by Ying Ding, Xinying Li, Wenlong Wang, Lei Cai

“…Subsequently, we preliminarily verified the regulation mechanisms of m5C-lncRNAs in vivo and in vitro experiments. A total of six m5C-lncRNAs and five immune cell types were selected to construct the risk score and immune risk score (IRS) model, respectively. …”
Get full text

Cohort profile: Health and Attainment of Pupils in a Primary Education National Cohort (HAPPEN) – a hybrid total population cohort in Wales, UK by Amrita Bandyopadhyay, Michaela James, Gareth Stratton, Sinead Brophy, Emily Marchant, Hope Jones, Amy Locke, Jonathan L Kennedy, David W E Burdett

“…Ongoing research includes the evaluation of interventions for primary school children such as natural experiment methods, free school meal roll-out in Wales, interventions to improve physical literacy including changes to the built environment and interventions to improve the health and well-being of primary school children.…”
Get full text