Effects of Polystyrene Microplastic Exposure on Liver Cell Damage, Oxidative Stress, and Gene Expression in Juvenile Crucian Carp (<i>Carassius auratus</i>) by Xiangtong Li, Yuequn Huang, Wenrong Li, Chaoyang Deng, Weiyuan Cao, Yi Yao

“…These four components demonstrated a relatively high level of responsiveness to PS-MP exposure and can be employed as ecotoxicological indicators of microplastics. (3) This experiment evaluated five genes in three treatments, which found that PS-MPs had different effects on gene expression in the liver and the tested genes were involved in different response pathways associated with virulence. …”
Get full text

Trying to Kill a Killer; Impressive Killing of Patient Derived Glioblastoma Cultures Using NK-92 Natural Killer Cells Reveals Both Sensitive and Highly Resistant Glioblastoma Cells by Jane Yu, Hyeon Joo Kim, Jordyn Reinecke, James Hucklesby, Tennille Read, Akshata Anchan, Catherine E. Angel, Euan Scott Graham

“…Moreover, long-term ECIS experiments reveal that the surviving glioblastoma cells were then able to grow and reseed the culture, which was evident 300–500 h after the addition of the NK-92 cells. …”
Get full text

The impact of weather conditions in different years on the biochemical composition of linseed oil by G. A. Popova, N. B. Rogalskaya, N. V. Knyazeva, V. M. Trofimova, T. V. Shelenga, E. A. Porokhovinova, N. B. Brutch

“…Practically all acids, except linoleic and linolenic ones, showed a very high random variation, which in our experiment included genotype × environment interaction. …”
Get full text

3D Point Cloud from Millimeter-wave Radar for Human Action Recognition: Dataset and Method by Biao JIN, Kangsheng SUN, Hao WU, Zixuan LI, Zhenkai ZHANG, Yan CAI, Rongmin LI, Xiangqun ZHANG, Genyuan DU

“…The network then leverages a series of Transformer encoding models to uncover temporal relationships across multiple point cloud frames. Extensive experiments reveal that the PETer network achieves exceptional recognition rates of 98.77% on the TI dataset and 99.51% on the Vayyar dataset, outperforming the traditional optimal baseline model by approximately 5%. …”
Get full text

Process Optimization and Antioxidant Activity of Pine Needle Essential Oil Extracted by Microwave-assisted Extraction by Suyuan LÜ, Bingqing SHANG, Luyan SUN, Guolong LIU, Fa ZHAO, Xiuqing LIANG, Qiu WU, Yue GENG

“…In the antioxidant experiment, L-ascorbic acid was used as a control to determine the DPPH and ABTS+ free radicals scavenging ability, and the half maximal inhibitory concentration (IC50) was 101.74 and 12.39 mg/mL, respectively. …”
Get full text

Earthworm inspired lubricant self-pumping hydrogel with sustained lubricity at high loading by Shuanhong Ma, Lunkun Liu, Weiyi Zhao, Renjie Li, Xiaoduo Zhao, Yunlei Zhang, Bo Yu, Ying Liu, Feng Zhou

“…The robust and sustained lubricity of the MS-SLH system is likely attributed to the synergy from the strong electrostatic repulsion effect at the sliding interface, the robust but compliant modulus of the dissociation lubrication layer, and the self-pumping lubricant release from the gland-like pocket of the texture pores during the dynamic shearing process. The demonstration experiments based on self-built equipments intuitively exhibit durable SL behavior of MS-SLH system. …”
Get full text

Use of implementation logic models in the Quadruple Aim QUERI: conceptualization and evolution by Russell E. Glasgow, Marina S. McCreight, Brianne Morgan, Heidi Sjoberg, Anne Hale, Lexus Ujano-De Motta, Lauren McKown, Rachael Kenney, Heather Gilmartin, Christine D. Jones, Joseph Frank, Borsika A. Rabin, Catherine Battaglia

“…Methods This paper describes our initial plans, experiences, and lessons learned from applying implementation logic models in the Quadruple Aim Quality Enhancement Research Initiative (QUERI) a large multi-study program funded by the Veterans Health Administration (VA). …”
Get full text

Experimental study on monitoring microwave ablation efficacy by real-time shear wave elastography in ex vivo porcine brain by Rui Li, Yukang Zhang, Linggang Cheng, Shuai Zheng, Hongbing Li, Hongxia Zhang, Lijuan Du, Wen He, Wei Zhang

“…The morphologic and microscopic changes of MWA tissues were observed, and the diameter of the ablation areas was measured. In this experiment, SWE is used to quantitatively evaluate brain tissue’s degree of thermal injury immediately after ablation.Results: This study It is found that the ablation range measured by SWE after ablation is in good consistency with the pathological range [ICCSWEL1-L1 = 0.975(95% CI:0.959 − 0.985), ICCSWEL2-L2 = 0.887(95% CI:0.779 − 0.938)]. …”
Get full text

A Study on Multi-Scale Behavior Recognition of Dairy Cows in Complex Background Based on Improved YOLOv5 by Zheying Zong, Zeyu Ban, Chunguang Wang, Shuai Wang, Wenbo Yuan, Chunhui Zhang, Lide Su, Ze Yuan

“…Moreover, it outperformed comparison models, including YOLOv4, YOLOv3, and Faster R-CNN, in complex background scenarios, multi-scale behavior detection, and behavior type discrimination. Ablation experiments further validate the effectiveness of the SA, DCNv3, and DyHead modules. …”
Get full text

LINC01271 promotes fracture healing via regulating miR-19a-3p/PIK3CA axis by Qinghua Chen, Lina Huang, Wenjun Ji, Miao Huang, Jincheng Sima, Jin Li, Hao Song, Wei Xiong, Bin Chen

“…Luciferase reporter assays, RIP experiments, and RNA pull-down assays were utilized to verify the target relationships between LINC01271 and miR-19a-3p, as well as between miR-19a-3p and PIK3CA. …”
Get full text

Exosomal circ_0006896 promotes AML progression via interaction with HDAC1 and restriction of antitumor immunity by Can Can, Xinyu Yang, Hexiao Jia, Hanyang Wu, Xiaodong Guo, Yihong Wei, Ziting Jia, Wancheng Liu, Amin Zhang, Na He, Hailei Zhang, Daoxin Ma

“…The role of circ_0006896 in the progression of AML was assessed by in vitro and in vivo functional experiments. Flow cytometry, RT-qPCR and adoptive T cell-transfer immunotherapy were conducted to assess the function of exosomal circ_0006896 in CD8+ T cell dysfunction. …”
Get full text

Control of two-spotted spider mite, Tetranychus urticae, on strawberry by integrating with cyetpyrafen and Phytoseiulus persimilis by Shan Zhao, Qiuyu Zhao, Xiaoyan Dai, Bing Lv, Ruijuan Wang, Zhenjuan Yin, Feng Zhang, Yan Liu, Long Su, Hao Chen, Li Zheng, Hongmei Li, Lixia Xie, Yifan Zhai

“…This efficacy increased to 96.04% by day 9 and was sustained until the experiment concluded on day 27. Field trials similarly showed a reduction in TSSM from 53.93 to 9.63 mites/leaf by day 6, achieving an 83.64% control efficiency, and culminated in a 98.46% reduction by day 10. …”
Get full text

A high-throughput platform for single-molecule tracking identifies drug interaction and cellular mechanisms by David Trombley McSwiggen, Helen Liu, Ruensern Tan, Sebastia Agramunt Puig, Lakshmi B Akella, Russell Berman, Mason Bretan, Hanzhe Chen, Xavier Darzacq, Kelsey Ford, Ruth Godbey, Eric Gonzalez, Adi Hanuka, Alec Heckert, Jaclyn J Ho, Stephanie L Johnson, Reed Kelso, Aaron Klammer, Ruchira Krishnamurthy, Jifu Li, Kevin Lin, Brian Margolin, Patrick McNamara, Laurence Meyer, Sarah E Pierce, Akshay Sule, Connor Stashko, Yangzhong Tang, Daniel J Anderson, Hilary P Beck

“…With this one experimental modality, we determined the potency, pathway selectivity, target engagement, and mechanism of action for identified hits. Kinetic htSMT experiments were capable of distinguishing between on-target and on-pathway modulators of ER signaling. …”
Get full text

An investigation of a hemophilia A female with heterozygous intron 22 inversion and skewed X chromosome inactivation by Xiaoyan Tan, Yi Yang, Xia Wu, Jing Zhu, Teng Wang, Huihui Jiang, Shu Chen, Shifeng Lou

“…X-chromosome inactivation experiments revealed unbalanced inactivation in the proband, leading to the silencing of the healthy X copy. …”
Get full text

Beyond averaging: A transformer approach to decoding event related brain potentials by Philipp Zelger, Manuel Arnold, Sonja Rossi, Josef Seebacher, Franz Muigg, Simone Graf, Antonio Rodríguez-Sánchez

“…Our investigation focuses on determining whether a transformer-based deep learning approach, specifically utilizing attention maps, an essential component of transformer networks, can provide deeper insights into ERP data compared to traditional averaging-based analyses.We investigated the data of an experiment on loudness perception. In the study, 29 normal-hearing participants between 18 and 30 years were presented with acoustic stimuli at five different sound levels between 65 and 95 dB and provided their subjective loudness rating, which was categorized as ”too loud” and ”not too loud”. …”
Get full text

Azospirillum brasilense and organomineral fertilizer co-inoculated with Bradyrhizobium japonicumon oxidative stress in soybean by Fernanda Barros, Reginaldo de Camargo, Regina Maria Lana, Miguel Henrique Franco, Mayara Cristiana Stanger, Vanderley José Pereira, Ernane Lemes

“…This study evaluated the efficacy of an organomineral fertilizer (sewage sludge-based) as a carrier for the Azospirillum brasilense inoculation and the influence of A. brasilense plus Bradyrhizobium japonicum on the soybean antioxidant metabolism.Method The experiment was performed under greenhouse conditions. …”
Get full text

Single-cell analyses of intestinal epithelium reveal the dysregulation of gut immune microenvironment in systemic lupus erythematosus by Qiaolin Wang, Yutong Wu, Lianlian Ouyang, Xiaoli Min, Meiling Zheng, Lingyu Gao, Xiaoyun Chen, Zhi Hu, Shuang Yang, Wenjuan Jiang, Sujie Jia, Qianjin Lu, Ming Zhao

“…The primary findings from scRNA-seq were further validated by quantitative polymerase chain reaction (qPCR), flow cytometry, and in vivo experiments including selenium supplementation. Results We observed a significant reduction in CD8αα + IELs, accompanied by a marked increase in CD8αβ + IELs in Lpr mice. …”
Get full text

Impacts of benchmarking choices on inferred model skill of the Arctic–Boreal terrestrial carbon cycle by Jeralyn Poe, Deborah Huntzinger, Nathan Collier, Christopher Schwalm, Jon Wells, Christina Schädel, William J Riley, Stephen Sitch

“…This analysis uses global datasets integrated into ILAMB and new, regionally-specific observational products from the Arctic–Boreal Vulnerability Experiment. Our results cover the overall time period of 1979–2019 and show that model scores can vary substantially depending on the data product applied, with higher model scores indicating better model performance against observations. …”
Get full text

A Study on the Dietary Yeast Polysaccharide Supplementation in Growth Performance, Antioxidant Capacity, and Immunity of Juvenile Largemouth Bass (<i>Micropterus salmoides</i>) by Junjie Qin, Haifeng Mi, Mingchun Ren, Dongyu Huang, Hualiang Liang, Lu Zhang, Tao Teng, Heng Yin

“…A total of 300 healthy fish (3.20 ± 0.03 g) were randomly divided into 15 floating cages (1 × 1 × 1 m) in five different groups, with three replicates per group, for an 8-week culture experiment. The 0.10Y and 0.20Y groups had significantly higher feed conversion ratios compared with the control group. …”
Get full text

Synergistic effects of PGPRs and fertilizer amendments on improving the yield and productivity of Canola (Brassica napus L.) by Haji Muhammad, Muhammad Ijaz, Abdul Sattar, Sami Ul-Allah, Ahmad Sher, Muhammad Asif, Muhammad Dilshad, Khalid Mahmood, Muhammad Waheed Riaz, Muhammad Saqlain Zaheer, Muhammad Rizwan, Salim Manoharadas

“…Insect pest management and other agronomic practices were carried out to maintain the experiment. Results Canola yield and agronomic traits were enhanced by the combination of Bacillus subtilis with the fully recommended N: P:K ratio (140:55:40 kg/ha). …”
Get full text