Paeonol Attenuates Methotrexate-Induced Cardiac Toxicity in Rats by Inhibiting Oxidative Stress and Suppressing TLR4-Induced NF-κB Inflammatory Pathway by Abdulla Y. Al-Taher, Mohamed A. Morsy, Rehab A. Rifaai, Nagwa M. Zenhom, Seham A. Abdel-Gaber

“…MTX cardiac toxicity was induced at the end of the fifth day of the experiment, with or without paeonol pretreatment. MTX-induced cardiac damage is evidenced by a distortion in the normal cardiac histological structure, with significant oxidative and nitrosative stress shown as a significant increase in NADPH oxidase-2, malondialdehyde, and nitric oxide levels along with a decrease in reduced glutathione concentration and superoxide dismutase activity compared to the control group. …”
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Evaluation of Melongosides as Potential Inhibitors of NS2B-NS3 Activator-Protease of Dengue Virus (Serotype 2) by Using Molecular Docking and Dynamics Simulation Approach by Partha Biswas, Ommay Hany Rumi, Dhrubo Ahmed Khan, Md Nasir Ahmed, Nusratun Nahar, Rownak Jahan, Md Nazmul Hasan Zilani, Tridib K Paul, Anamul Hasan, Tohmina Afroze Bondhon, Khoshnur Jannat, Md Nazmul Hasan, Mohammed Rahmatullah

“…However, the 200 ns molecular dynamic simulation experiment indicates significant stability of the protein-ligand interactions with the RMSD values of 2.5 Å, thus suggesting a better docking position and no disruption of the protein-ligand structure. …”
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Understanding recruitment to a perioperative randomised controlled trial: protocol for a mixed-methods substudy nested within a feasibility trial of octreotide infusion during live... by Duncan Wagstaff, S Ramani Moonesinghe, Jez Fabes, Michael Spiro, Edgar Brodkin, Ee-Neng Loh, Vivienne Hannon

“…This is a substudy within a feasibility randomised controlled trial of octreotide infusion during liver transplantation at two National Health Service hospitals, which will evaluate patient and staff experiences of trial processes. By sharing formative understanding from these methods with the trials team we aim to improve staff–patient interactions and hence recruitment rates.Methods and analysis This prospective mixed-methods study will comprise two workstreams. …”
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Effectiveness of the barley cultivar ‘Bios 1’ as source material for breeding by N. A. Zhilin, I. Yu. Zaytseva, I. N. Shchennikova, S. A. Emelev

“…According to the results of laboratory experiments and competitive variety trials, 5 mutant forms of barley were identified as promising. …”
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Association among financial toxicity, depression and fear of cancer recurrence in young breast cancer patient-family caregiver dyads: an actor-partner interdependence mediation mod... by Tianye Yang, Zhu Zhu, Jianjun Shi, Lingling Tong, Jia Yang, Songli Mei, Hui Ren

“…Clinical implications The study emphasized the importance of addressing the experiences of both patient and family caregivers in clinical interventions. …”
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Weak neutral current axial form factor using ν ¯ ν $$ \left(\overline{\nu}\right)\nu $$ -nucleon scattering and lattice QCD inputs by Raza Sabbir Sufian, Keh-Fei Liu, David G. Richards

“…We then perform a phenomenological analysis, where we combine the strange quark electromagnetic form factor from lattice QCD with (anti)neutrino-nucleon scattering differential cross section from MiniBooNE experiments in a momentum transfer region 0.24 ≲ Q2 ≲ 0.71 GeV2 to determine the neutral current weak axial form factor G A Z Q 2 $$ {G}_A^Z\left({Q}^2\right) $$ in the range of 0 ≲ Q2 ≤ 1 GeV2. …”
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Effects of Organic Nutrient Sources and NPS Fertilizer on the Agronomic and Economic Performance of Haricot Bean (Phaseolus vulgaris L.) in Southern Ethiopia by Ermias Elka, Fanuel Laekemariam

“…The organic materials used were Croton (Croton macrostachyus) and Erythrina (Erythrina brucei) at 2 : 1 ratio, respectively. The experiment was laid out in a randomized complete block design with three replications. …”
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A simple and highly efficient protocol for 13C-labeling of plant cell wall for structural and quantitative analyses via solid-state nuclear magnetic resonance by Tasleem Javaid, Akshayaa Venkataraghavan, Matrika Bhattarai, Debkumar Debnath, Wancheng Zhao, Tuo Wang, Ahmed Faik

“…This level of 13C-enrichment is sufficient for all conventional 2D and 3D correlation ssNMR experiments for detailed analysis of plant cell wall structure. …”
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Anger Emotional Stress Influences VEGF/VEGFR2 and Its Induced PI3K/AKT/mTOR Signaling Pathway by Peng Sun, Sheng Wei, Xia Wei, Jieqiong Wang, Yuanyuan Zhang, Mingqi Qiao, Jibiao Wu

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ML-NIC: accelerating machine learning inference using smart network interface cards by Raghav Kapoor, David C. Anastasiu, Sean Choi

“…ML-NIC deploys models directly into the computational cores of the devices to efficiently leverage the inherent parallelism capabilities of network devices, thus providing huge latency and throughput gains. Our experiments show that ML-NIC reduced inference latency by at least 6 × on average and in the 99th percentile and increased throughput by at least 16x with little to no degradation in model effectiveness compared to the existing CPU solutions. …”
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Utilizing liquid-liquid biopolymer regulators to predict the prognosis and drug sensitivity of hepatocellular carcinoma by Jianhao Li, Han Chen, Lang Bai, Hong Tang

“…To validate our findings, we collected 49 HCC cases along with adjacent tissue samples and confirmed the correlation between DCAF13 expression and HCC progression through qRT-PCR analysis and in vitro experiments. Results LPRS was established with 8 LLPS-related genes (TXN, CBX2, DCAF13, SLC2A1, KPNA2, FTCD, MAPT, and SAC3D1). …”
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Research on water and fertilizer irrigation system of tea plantation by Xuetao Jia, Ying Huang, Yanhua Wang, Daozong Sun

“…Diamond deployment is used in the network, and the networking experiments were conducted comparing with random deployment. …”
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Finding the best column for polar basic analytes across reversed-phase and hydrophilic interaction liquid chromatography by József Simon, Márton Kovács, Pál T. Szabó

“…On the one hand, the standard experiments use C18 columns, which is usually unsuitable. …”
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Bilevel Optimization of Regular Bus-Subway-Shared Bicycle Cooperative Operation considering Dual Uncertainties by Yunqiang Xue, Tong He, Tao Li, Hongzhi Guan, Yang Qiu

“…The research outcomes hold significant practical implications for facilitating the efficient and cooperative development of urban transportation networks, ultimately enhancing the convenience of residents’ travel experiences.…”
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E-waste recycling in an optimized way for copper recovery by leaching and a case study on E-waste generation and management in Dhaka city by Kaniz Fatema, Md Niamul Hassan, Sanjida Hasan, Hridoy Roy

“…A combination of experimental procedures and computational modeling was employed to optimize copper extraction from printed circuit boards (PCBs). The experiments involved treating PCBs with iron-based solutions of different concentrations and testing the effectiveness over two distinct time periods. …”
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Quality Evaluation of Bioactive Ingredients in Lianhua Qingwen Capsule Based on Quantitative Analysis of Multicomponent by the Single Marker Method and the Chemical Recognition Pat... by Qianqian Zhou, Lin Yang, Yiwu Wang, Jiajia Zou, Shuya Li, Lei Dai, Yan Li, Dan He

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Biomimetic Rotary Tillage Blade Design for Reduced Torque and Energy Requirement by Yuwan Yang, Jin Tong, Yuxiang Huang, Jinguang Li, Xiaohu Jiang

“…Results showed that BB-1 and BB-2 averagely reduced the torque by 13.99% and 3.74% compared with CB, respectively. The field experiment results also showed the excellent soil-cutting performance of BB-1 whose average torques were largely reduced by 17.00%, 16.88%, and 21.80% compared with CB at different rotary speeds, forward velocities, and tillage depths, respectively. …”
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Modern possibilities of tear film stability restoration by V.V. Brzheskiy, G.G. Кim, V.А. Bobryshev

“…In vitro and in vivo experiments have proven the possibility of using such modified hyaluronic acid as an artificial tear substitute. …”
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Study of the deformation of sponge application hemostatic materials by V. A. Lipatov, D. A. Severinov, M.D. Z. Naimzda, E. L. Puchkova

“…To evaluate the dynamics of deformation of spongy application hemostatic materials in an in vitro experiment. Materials and methods. As materials of the study the following samples of hemostatic materials were used: Tachocomb (No. 1), Gelita-Spon Standard (No. 2), Reggicel Fibrillar (No. 3), samples of hemostatic sponges developed jointly with Lintex (St.Petersburg, Russia) on the basis of sodium-Carboxymethyl Cellulose (No. 3): Samples were placed on a glass substrate which was mounted on the rising REM cross-arm 0.2–1 to estimate 50% compression residual strain. …”
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Research on the Impact of Different Force Directions on the Mechanical Properties and Damage Evolution Law of Sandstone with Different Hole Diameters by Fukun Xiao, Renhe Li, Le Xing

“…In this research, a uniaxial acoustic emission experiment was conducted on rock samples with different positions and diameters of the hole, and an analysis was made on the impact of different hole positions and diameters on the mechanical properties, failure, energy conversion, and acoustic emission-caused damage characteristics and laws of the rock samples. …”
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