Single-cell RNA-seq reveals immune cell heterogeneity and increased Th17 cells in human fibrotic skin diseases by Cheng-Cheng Deng, Xue-Yan Xu, Yan Zhang, Long-Can Liu, Xuan Wang, Jun-Yi Chen, Liu-Yi Yao, Ding-Heng Zhu, Bin Yang

“…Ki-67 staining, a scratch experiment, real-time PCR, and Western blotting were used to explore the effect of the Th17 cell supernatant on keloid fibroblasts.ResultsOur findings revealed the intricate cellular landscape of immune cells in fibrotic skin diseases. …”
Get full text

Influencing Factors’ Analysis of Disturbance Degree of Key Stratum Based on the Response Surface Method by Yang Li, Nan Wang, Yuqi Ren, Xiangji Ou, Yikun Liu, Junbo Luo, Canqi Mei

“…Through the response surface method, experiments of three factors (mining height, buried depth, and interlayer spacing) with three different lithology types (soft, medium, and hard) between key stratum and coal seam are signed. …”
Get full text

Utilization of Catfish Body Fat in the Diet of Tilapia Oreochromis niloticus by Mia Setiawati, C. Nuraeni, D. Jusadi

“… This experiment was conducted to evaluate the effect of catfish body fat in the diet on the growth of tilapia Oreochromis niloticus. …”
Get full text

Effects of Nitrogen Fertilization and Nitrogen Fixing Endophytic Bacteria Supplementation on Soil Fertility, N Uptake, Growth, and Yield of Sesame (Sesamum indicum L.) Cultivated o... by Le Vinh Thuc, Tran Ngoc Huu, Trinh Minh Ngoc, Nguyen Hong Hue, Le Thanh Quang, Do Thi Xuan, Tran Chi Nhan, Ly Ngoc Thanh Xuan, Le Thi My Thu, Isao Akagi, Jun-Ichi Sakagami, Nguyen Quoc Khuong

“…The aim of this study was to determine the proper combination of nitrogen (N) fertilizer level and nitrogen fixing endophytic bacteria (NFEB) supplementation for the maximum grain yield of sesame cultivated in alluvial soil in dykes. The experiment followed a completely randomized block design with two factors. …”
Get full text

Effective interventions to prevent youth vaping behaviours: a rapid review by Ana Paula Belon, Laura Nieuwendyk, Tasha Allen, Melissa Worrell, Candace I J Nykiforuk

“…Methodological quality was assessed using the Effective Public Health Practice Project Quality Assessment Tool.Results 20 studies were included: 45% were experiments or quasiexperiments, 85% reported data from the USA, 65% were non-policy interventions and 40% and 35% measured susceptibility and attitudes and behaviours related to vaping, respectively. …”
Get full text

Cost-Effective Treatment of Hemihydrate Phosphogypsum and Phosphorous Slag as Cemented Paste Backfill Material for Underground Mine by Xilong Xue, Yuxian Ke, Qian Kang, Qinli Zhang, Chongchun Xiao, Fengjian He, Qing Yu

“…After this, the underground environmental impact of CPB-based HPG and PS was investigated through a dynamic leachability experiment. The results show that (1) the UCS of CPB increases with the increase of the HPG content and mass fraction, and the addition of 3% quicklime can eliminate CO2, H2S, and SO2 generated from the slurry of CPB-based HPG-PS; (2) the addition of 3% quicklime and 5% cement to the HPG-PS mixtures can offset the strength loss of CPB in the late curing stage; (3) the UCS of the recommended specimen reaches 1.15–3.32 MPa after curing from 7 to 28 days, with their slump values varying from 15 mm to 26 mm, and the bleeding rates between 0.87% and 1.15%, which can meet the technical requirements of mining methods; (4) the UCS of CPB is the result of the cohydration reaction of hemihydrate gypsum (HG) in HPG and active Al2O3 and SiO2 in PS; and (5) the leaching indexes meet Category IV of the Chinese Groundwater Quality Standard (DZ/T 0290-2015). …”
Get full text

Deep Ensemble Learning for Human Action Recognition in Still Images by Xiangchun Yu, Zhe Zhang, Lei Wu, Wei Pang, Hechang Chen, Zhezhou Yu, Bin Li

“…More importantly, the model complexity can be reduced by lessening the number of trainable parameters, thereby effectively mitigating overfitting issues of the model in small datasets to some extent. We conduct experiments in Li’s action dataset, uncropped and 1.5x cropped Willow action datasets, and the results have validated the effectiveness and robustness of our proposed models in terms of mitigating overfitting issues in small datasets. …”
Get full text

A computational time integrator for heat and mass transfer modeling of boundary layer flow using fuzzy parameters by Muhammad Shoaib Arif, Wasfi Shatanawi, Yasir Nawaz

“…Stability and convergence analyses show that the method provides a 15 % improvement in accuracy compared to first-order methods and a 10 % improvement over second-order methods, particularly at time step sizes of Δt=0.01. Numerical experiments validate the accuracy and efficiency of the approach, showing significant improvements in modelling the influence of uncertainty on heat and mass transfer. …”
Get full text

Navigating ALICE: Advancements in Deployable Docking and Precision Detection for AUV Operations by Yevgeni Gutnik, Nir Zagdanski, Sharon Farber, Tali Treibitz, Morel Groper

“…The proposed method was validated through software-in-the-loop simulations, controlled seawater pool experiments, and preliminary open-sea trials, including several docking attempts. …”
Get full text

Magnitude and Associated Factors of Unintended Pregnancy among Pregnant Women at Saesie Tsaeda Emba Woreda Eastern Zone of Tigray, North Ethiopia, 2018 by Gebrehiwot Gebremariam Weldearegawi, Kidanemaryam Berhe Tekola, Berhane Fseha Teklehaymanot

“…In Ethiopia, around one third of women have experiences of unintended pregnancy. However, the magnitude of unintended pregnancy was not determined in the study area. …”
Get full text

Influences of True Triaxial Loading-Unloading Stress Paths on Mechanical Properties and Wave Velocity of Coal Samples subject to Risk of Rock Burst by Wei Shen, Guang-Jian Liu, Lin-Ming Dou, Si-Yuan Gong, Hu He

“…The triaxial stress-time curves obtained by experiments and simulations exhibited an “elasticity-yield-destruction” phase, and the characteristics of the yield phase were determined by the RURLR. …”
Get full text

Coupling Action of Cooling and Dynamic Load Impact on Deformation Characteristics of High-Salinity Saline Soils by Yu Zhang, Meisi Zou, Runze Tian, Anhua Xu, Yunlong Hou, Bingbing Han, Xuemei Li

“…Firstly, the freezing temperature experiment was carried out on SS (sandy silt) and HS (high-sulfate silty clay). …”
Get full text

Study on the Mechanism of Black Phosphorus Nanosheets Loading Sr2+ Used in Photothermal Antibacterial Treatment by Ma G, Li B, Diao J, Zhang Y, Zhang B, Wu D, Gui H, Zhong J, Zhu H, Zhang D

“…Black phosphorus (BP) is an emerging nanoparticle that can generate heat under the action of near-infrared light, it can safely and effectively kill bacteria through photothermal therapy. In this experiment, black phosphorus was used as a photothermal agent to kill bacteria and strontium ions were loaded onto BP to enhance its stability and antibacterial performance.Methods: BP was obtained by liquid phase exfoliation and Sr2+ was loaded onto the surface of BP by electrostatic interaction.Results: BP-Sr was synthesized via electrostatic interactions and characterized using various techniques. …”
Get full text

Simultaneous Determination of Mineral Nutrients and Toxic Metals in M. stenopetala from Southern Ethiopia: A Comparative Study of Three Cultivating Areas Using MP-AES by Ashenafi Shemnsa, Wondimeneh Dubale Adane, Merid Tessema, Endale Tesfaye, Gizaw Tesfaye

“…The efficiency of the optimized procedure was validated by spiking experiments, and the percentage recovery ranged between 94 and 110%. …”
Get full text

Genetic diversity of barley accessions from East Asian countries in terms of resistance to powdery mildew by R. A. Abdullaev, K. A. Lukina, B. A. Batasheva, O. N. Kovaleva, E. E. Radchenko

Get full text

Heterologous Expression and Adaptive Evolution of ε-Poly-lysine Synthase Gene in <i>Corynebacterium glutamicum</i> by Long Pan, Yihang Chen, Aimei Liao, Yinchen Hou, Jihong Huang

“…Its ability to produce high amounts of L-lysine can provide sufficient precursor substances for the synthesis of ε-PL, making it an ideal strain for the heterologous expression of ε-PL synthase genes (<i>pls</i>). In this experiment, a recombinant <i>C. glutamicum</i> capable of synthesizing ε-PL and exhibiting certain physiological resistance to ε-PL was obtained by amplifying <i>pls</i> and heterologous expression in <i>C. glutamicum</i> for the first time. …”
Get full text

Virtual consultation in kidney care: a mixed-methods study on a model for safe and effective integration into routine clinical care by Aminu K Bello, Stephanie Thompson, Deenaz Zaidi, Scott Klarenbach, Feng Ye, Terry J Smith, Mark Courtney

“…This study evaluated the integration of virtual outpatient consultation safely and effectively into the kidney care programme in Alberta.Study design We leveraged a mixed-methods approach to collate data about clinicians’ experiences and opinions, forming the basis for the qualitative part of the study.Data extraction Data were collected through surveys, interviews and focus groups of nephrologists and home dialysis nurses.Analytical approach Focus group/interview transcripts for nephrologists and nurses were used to generate initial codebooks, which were iteratively refined throughout the analysis. …”
Get full text

Web-Based Exercise and Nutrition Intervention to Improve Leg Muscle Strength and Physical Functioning in Older Adults: Pre-Post Pilot Study by Berber Gijsbertha Dorhout, Nick Wezenbeek, Lisette C P G M de Groot, Pol Grootswagers

“…Semistructured interviews were used to gather experiences of participants. Atlas.ti version 22 was used to analyze the interviews. …”
Get full text

Test Performance of Plastic Waste Shredder Machine and Analyze the Quality of the Shredded Plastic Product Using the Taguchi Method by Adam - Kamil, Hendra Hendra, Sidik Susilo, Erny Listijorini, Hernadewita Hernadewita

“…The purpose of this research is to get the maximum capacity of plastic Waste shredding, and to know the production capacity of plastic waste in one process of enumeration. The experiment method is used in this research to get the performance of the machine like voltage, power, cutting force of tool, and cutting speed. …”
Get full text

Local democracy and forms of direct citizen participation in governance: Case study Serbia by Radojević Mijodrag

“…Based on empirical data, comparative experiences and legal standards, the author believes that the solution lies in reviving the application of direct democracy at the local level.…”
Get full text