Retinoic Acid Signal Negatively Regulates Osteo/Odontogenic Differentiation of Dental Pulp Stem Cells by Jiangyi Wang, Guoqing Li, Lei Hu, Fei Yan, Bin Zhao, Xiaoshan Wu, Chunmei Zhang, Jinsong Wang, Juan Du, Songlin Wang

“…In vivo transplantation experiments suggested that osteo/odontogenic differentiation potential of DPSCs was enhanced by inversing RA signal. …”
Get full text

Super‐Enhancer‐Driven IRF2BP2 is Activated by Master Transcription Factors and Sustains T‐ALL Cell Growth and Survival by Juanjuan Yu, Zimu Zhang, Yanling Chen, Jianwei Wang, Gen Li, Yanfang Tao, Yongping Zhang, Yang Yang, Chenyue Zhang, Tiandan Li, Jia Cheng, Tongtign Ji, Zhongling Wei, Wenjuan Wang, Fang Fang, Wei Jiang, Peipei Chu, Hongli Yin, Di Wu, Xiaolu Li, Xiaodong Wang, Jun‐Jie Fan, Shaoyan Hu, Zhen‐Hong Zhu, Shuiyan Wu, Jun Lu, Jian Pan

“…However, in vitro and in vivo experiments demonstrated that IRF2BP2 is crucial for T‐ALL cell growth and survival. …”
Get full text

De novo assembly of the complete mitochondrial genomes of two Camellia-oil tree species reveals their multibranch conformation and evolutionary relationships by Zhun Xiao, Yiyang Gu, Junqin Zhou, Mengqi Lu, Jinfeng Wang, Kaizheng Lu, Yanling Zeng, Xiaofeng Tan

“…Both genomes exhibit a multipartite genome structure, which is supported by our PCR experiments. We conducted codon usage and RNA editing site analysis on these two mitogenomes, which showed highly consistent results. …”
Get full text

Evaluation of the Effectiveness of Using STEAM Projects in Teaching Physics: Student Interest in the Field of Solar Energy by Amin Pattayev, Naci Genc, Sherzod Ramankulov, Serik Polatuly, Meirbek Tuiyebayev, Indira Usembayeva, Gulnara Rizakhojayeva

“…Therefore, at present, the organization of advanced STEAM experiments and the effective use of STEAM educational software are taking an increasingly important place in the education system of developed countries. …”
Get full text

Multimodal Fusion and Cutting-Edge AI-Based Smart Vending Machines for Electronic Component Management by M. Karthiga, Syarifah Bahiyah Rahayu, E. Suganya, S. Sankarananth, S. Sountharrajan, K. Venkatesan

“…The algorithm’s effectiveness is particularly noticeable in its low GPU time consumption, which is important for real-time applications. Ablation experiments in various settings further validate the algorithm’s efficacy, particularly in identifying small electrical components. …”
Get full text

FreshWater Watch: Investigating the Health of Freshwater Ecosystems, from the Bottom Up by Isabel Bishop, Amedeo Boldrini, Wim Clymans, Charlotte Hall, Heather Moorhouse, Stephen Parkinson, Kesella Scott-Somme, Ian Thornhill, Steven Loiselle

“…We present laboratory and field experiments conducted to validate chemical and optical methods. …”
Get full text

Compost from the food waste for organic production of cabbage, cauliflower, and radish under sub-tropical conditions by Neha Kumari, Anit Sharma, Mamta Devi, Atif Zargar, Sunny Kumar, Umesh Thakur, Ajay Bhatia, Khushboo Badhan, Sunaina Chandel, Arpana Devi, Kriti Sharma, Shweta Kumari, Mussarat Choudhary, Arup Giri

“…In this context, a field study conducted on the effects of compost prepared from food wastage on the yield of cabbage, cauliflower, and radish. Methods The experiment consisted of twelve treatments and twelve control plants of all the plants. …”
Get full text

ED‐AttConvLSTM: An Ionospheric TEC Map Prediction Model Using Adaptive Weighted Spatiotemporal Features by Liangchao Li, Haijun Liu, Huijun Le, Jing Yuan, Haoran Wang, Yi Chen, Weifeng Shan, Li Ma, Chunjie Cui

“…The inclusion of the attention mechanism enhances the efficient utilization of spatiotemporal features extracted by the ConvLSTM, emphasizing the significance of crucial spatiotemporal features in the prediction process and, as a result, leading to an enhancement in predictive performance. We conducted experiments in East Asia (10°N–45°N, 90°E−130°E). The ED‐AttConvLSTM was trained and evaluated using the International GNSS Service TEC maps over a period of six years from 2013 to 2015 (high solar activity years) and 2017 to 2019 (low solar activity years). …”
Get full text

Tailoring the electron redistribution of RuO2 by constructing a Ru-O-La asymmetric configuration for efficient acidic oxygen evolution by Cong-Hui Li, Cheng-Zong Yuan, Xiaolei Huang, Hongrui Zhao, Fuling Wu, Lei Xin, Xiaomeng Zhang, Shufeng Ye, Yunfa Chen

“…Specifically, the as-prepared optimal La0.1Ru0.9O2 shows a low overpotential of 188 ​mV at 10 ​mA ​cm−2, a high mass activity of 251 A gRu−1 at 1.6 ​V vs. reversible hydrogen electrode (RHE), and a long-lasting durability of 63 ​h, far superior to the 8 ​h achieved by standard RuO2. Experiments and density functional theory calculations jointly reveal that the Ru-O-La asymmetric configuration could trigger electron redistribution in RuO2. …”
Get full text

Transcriptome analysis unveils the mechanisms of oxidative stress, immunotoxicity and neurotoxicity induced by benzotriazole UV stabilizer-328 in zebrafish embryos by Xinlu Yang, Yijing Gan, Menghuan Zhang, Shaolin Xie, Mingfu Lin, Lixiang Zhong, Mengke Song, Jun Wang, Yumei Huang

“…In particular, the immunotoxicity and neurotoxicity of UV-328 to aquatic organisms and their mechanisms have not been reported yet. In this experiment, the developmental toxicity, oxidative stress, apoptosis, immunotoxicity and neurotoxicity in zebrafish embryos exposed to UV-328 with concentrations of 0.01, 0.1, 1, 10 and 100 µg/L for 120 h were studied. …”
Get full text

The Fungi-specific histone Acetyltransferase Rtt109 mediates morphogenesis, Aflatoxin synthesis and pathogenicity in Aspergillus flavus by acetylating H3K9 by Ruilin Sun, Meifang Wen, Lianghuan Wu, Huahui Lan, Jun Yuan, Shihua Wang

“…Through the maize seed infection experiment, we found that the growth of △rtt109 on the surface of affected corn was largely reduced, and the amount of aerial mycelium decreased significantly, which was consistent with the results on the artificial medium. …”
Get full text

AdipoR1 enhances the radiation resistance via ESR1/CCNB1IP1/cyclin B1 pathway in hepatocellular carcinoma cells by Yuhan Gan, Linhui Zhu, Yimo Li, Ruoting Ge, Jiahe Tian, Yuxin Chen, Xiang He, Shumei Ma, Xiaodong Liu

“…KEGG enrichment analysis indicated that the cell cycle and ubiquitination degradation pathways may be involved in the regulation of radiation resistance by AdipoR1.The knockdown of AdipoR1 can attenuate the radiation-induced G2/M phase arrest through cyclin B1.By the ubiquitination IP assay and a rescue experiment, we confirmed that CCNB1IP1 regulated the ubiquitination and degradation of cyclin B1. …”
Get full text

DeepGlioSeg: advanced glioma MRI data segmentation with integrated local-global representation architecture by Ruipeng Li, Yuehui Liao, Yueqi Huang, Xiaofei Ma, Guohua Zhao, Yanbin Wang, Chen Song

“…Test-time augmentation (TTA) and volume-constrained (VC) post-processing are subsequently applied to refine the final segmentation outputs.ResultsExtensive experiments were conducted on three publicly available glioma MRI datasets and one privately owned clinical dataset. …”
Get full text

Advanced KNN-based cost-efficient algorithm for precision localization and energy optimization in dynamic underwater sensor networks by Nadia Shamshad, Lei Wang, Kiran Saleem, Danish Sarwr, Salil Bharany, Ahmad Almogren, Jaeyoung Choi, Ateeq Ur Rehman, Ayman Altameem

“…The effectiveness of the proposed KNN-based cost-efficient method is evaluated through real-time experiments conducted in a water tank setup and simulations using the Ns-3.37 version. …”
Get full text

OSAD: Open-Set Aircraft Detection in SAR Images by Xiayang Xiao, Zhuoxuan Li, Xiaolin Mi, Dandan Gu, Haipeng Wang

“…PCL employs prototype-based contrastive encoding loss to promote instance-level intraclass compactness and interclass variance, aiming to minimize the overlap between known and unknown distributions and reduce the empirical classification risk of known categories. Extensive experiments have demonstrated that the proposed method can effectively detect unknown objects and exhibit competitive performance without compromising closed-set performance. …”
Get full text

Evaluation of ampicillin plus ceftobiprole combination therapy in treating Enterococcus faecalis infective endocarditis and bloodstream infection by Simone Giuliano, Jacopo Angelini, Floriana Campanile, Paola Conti, Sarah Flammini, Alberto Pagotto, Francesco Sbrana, Luca Martini, Denise D’Elia, Mohd H. Abdul-Aziz, Menino O. Cotta, Jason A. Roberts, Robert A. Bonomo, Carlo Tascini

“…Our analysis included the study of E. faecalis biofilm production, as well as the kinetics of bacterial killing of ceftobiprole alone or in combination with ampicillin. Time-kill experiments revealed strong bactericidal activity of ceftobiprole alone at concentrations four times higher than the MIC for some enterococcal strains. …”
Get full text

CDPMF-DDA: contrastive deep probabilistic matrix factorization for drug-disease association prediction by Xianfang Tang, Yawen Hou, Yajie Meng, Zhaojing Wang, Changcheng Lu, Juan Lv, Xinrong Hu, Junlin Xu, Jialiang Yang

“…Extensive cross-validation experiments on three standard datasets show that CDPMF-DDA achieves an average AUC of 0.9475 and an AUPR of 0.5009, outperforming existing models. …”
Get full text

Sterol‐Targeted Laboratory Evolution Allows the Isolation of Thermotolerant and Respiratory‐Competent Clones of the Industrial Yeast Saccharomyces cerevisiae by Isabel‐Elena Sánchez‐Adriá, Jose A. Prieto, Gemma Sanmartín, Miguel Morard, Estéfani García‐Ríos, Francisco Estruch, Francisca Randez‐Gil

“…Notably, all evolved clones exhibited specific point mutations in MPM1 (P50S) and PDR1 (F749S). CRISPR‐Cas9 experiments confirmed the role of the pdr1F749S mutation in the FCNZ‐tolerance phenotype and demonstrated that Mpm1 is required for growth at high temperatures. …”
Get full text

The motion law of oil droplets and bubbles in air flotation-cyclone by WANG Wei, BAI Xu, CHU Xiaodan, ZHAO Xiang, MA Xueliang, LIN Wei, GONG Cheng, YU Jiuyang

“…In static water conditions, the average projected area of microbubble-floc aggregates was approximately six times that of microbubble-oil droplet aggregates, indicating that the addition of flocculants was conducive for improving oil-water separation. Interaction experiments demonstrated that, compared to pure water static settling, oil content in wastewater decreased by 38.7%, 71.4%, and 76.5% after treatment using microbubble air flotation, flotation+cyclone, and flotation+cyclone+flocculants, respectively. …”
Get full text

Extended homogeneous field correction method based on oblique projection in OPM-MEG by Fulong Wang, Fuzhi Cao, Yujie Ma, Ruochen Zhao, Ruonan Wang, Nan An, Min Xiang, Dawei Wang, Xiaolin Ning

“…We compared the opHFC with four benchmark methods by simulations and auditory and somatosensory evoked OPM-MEG experiments. The results demonstrate that opHFC provides superior noise suppression with minimal distortion, enhancing the signal quality at the sensor and source levels. …”
Get full text