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201
Cov-trans: an efficient algorithm for discontinuous transcript assembly in coronaviruses
Published 2024-12-01“…However, traditional transcript assembly methods primarily designed for variable alternative splicing events in eukaryotes are not suitable for the viral transcript assembly problem. …”
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202
Pseudorabies virus infection triggers pUL46-mediated phosphorylation of connexin-43 and closure of gap junctions to promote intercellular virus spread.
Published 2025-01-01“…Gap junctions (GJs) play a pivotal role in intercellular communication between eukaryotic cells, including transfer of biomolecules that contribute to the innate and adaptive immune response. …”
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203
Protein Profiling and Histone Deacetylation Activities in Somaclonal Variants of Oil Palm (Elaeis guineensis Jacq.)
Published 2013-01-01“…Histone deacetylases (HDACs), involved in eukaryotic gene regulation by catalyzing the acetyl groups are removal from lysine residues on histone, hence transcriptionally repress gene expression. …”
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204
Mechanisms of miRNA-Mediated Gene Regulation from Common Downregulation to mRNA-Specific Upregulation
Published 2014-01-01“…Discovered in 1993, micoRNAs (miRNAs) are now recognized as one of the major regulatory gene families in eukaryotes. To date, 24521 microRNAs have been discovered and there are certainly more to come. …”
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205
Comparative genomics of Aspergillus nidulans and section Nidulantes
Published 2025-01-01“…Aspergillus nidulans is an important model organism for eukaryotic biology and the reference for the section Nidulantes in comparative studies. …”
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206
Global atlas of predicted functional domains in Legionella pneumophila Dot/Icm translocated effectors
Published 2024-11-01“…Abstract Legionella pneumophila utilizes the Dot/Icm type IVB secretion system to deliver hundreds of effector proteins inside eukaryotic cells to ensure intracellular replication. …”
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207
The history of Drosophila studies: steps in the development of genetics
Published 2015-07-01“…Owing to Drosophila’s biologic features, it became a universal eukaryotic model for genetic, embryological, morphological, physiological, molecular, and cellular studies. …”
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208
Development of a differentiating of infected from vaccinated animal (DIVA) ELISA to detect antibodies against Senecavirus A in pigs using two expression systems of non-structural p...
Published 2025-12-01“…Different expression systems (eukaryotic and prokaryotic) were used to express recombinant proteins. …”
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209
eEF-2K Deficiency Boosts the Virus-Specific Effector CD8<sup>+</sup> T Cell Responses During Viral Infection
Published 2024-12-01“…In this study, we revealed a critical role of eukaryotic elongation factor-2 kinase (eEF-2K), a negative regulator of protein synthesis, in regulating T cells during vaccinia virus (VACV) infection. …”
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210
eIF3 engages with 3’-UTR termini of highly translated mRNAs
Published 2025-01-01“…Here, we investigate the role of eukaryotic initiation factor 3 (eIF3) in early differentiation of human pluripotent stem cell (hPSC)-derived neural progenitor cells (NPCs). …”
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211
Excitable Ras dynamics-based screens reveal RasGEFX is required for macropinocytosis and random cell migration
Published 2025-01-01“…Abstract Excitable systems of eukaryotic chemotaxis can generate asymmetric signals of Ras-GTP-enriched domains spontaneously to drive random cell migration without guidance cues. …”
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212
Lawsonia intracellularis T3SS effector LI0758, an Rce1 ortholog, activates MAPK and NF-κB signaling in mammalian cells
Published 2025-02-01“…Bioinformatics analyses indicate that LI0758 is an ortholog of Rce1, a eukaryotic CAAX protein endoprotease, sharing a similar subcellular localization on the endoplasmic reticulum (ER). …”
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213
Periodic Distribution of a Putative Nucleosome Positioning Motif in Human, Nonhuman Primates, and Archaea: Mutual Information Analysis
Published 2013-01-01“…Alu repetitive elements contribute to the most fundamental structure of nucleosome positioning in higher Eukaryotes. In some regions of primate chromosomes, the distribution of the decamer shows symmetrical patterns including inverted repeats.…”
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214
Sir2 and Fun30 regulate ribosomal DNA replication timing via MCM helicase positioning and nucleosome occupancy
Published 2025-01-01“…The association between late replication timing and low transcription rates in eukaryotic heterochromatin is well known, yet the specific mechanisms underlying this link remain uncertain. …”
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215
Hydrogenases – Types, Sources, Properties, and the Potential for Their Application
Published 2025-01-01“…We explore their background, classification, and phylogeny, highlighting their presence in many different sources in nature, such as bacteria, archaea, and certain eukaryotes. We also discuss key factors influencing their activity, along with their advantages and disadvantages. …”
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216
Functional Characterization of the Canine Heme-Regulated eIF2α Kinase: Regulation of Protein Synthesis
Published 2009-01-01“…The heme-regulated inhibitor (HRI) negatively regulates protein synthesis by phosphorylating eukaryotic initiation factor-2α (eIF2α) thereby inhibiting protein translation. …”
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217
Genome-wide identification and analysis of the NF-Y transcription factor family reveal its potential roles in tobacco (Nicotiana tabacum L.)
Published 2025-12-01“…Nuclear Factor Y (NF-Y) represents a group of transcription factors commonly present in higher eukaryotes, typically consisting of three subunits: NF-YA, NF-YB, and NF-YC. …”
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218
Alternative Splicing of Cdh23 Exon 68 Is Regulated by RBM24, RBM38, and PTBP1
Published 2020-01-01“…Alternative splicing plays a pivotal role in modulating the function of eukaryotic proteins. In the inner ear, many genes undergo alternative splicing, and errors in this process lead to hearing loss. …”
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219
ALKBH5 suppresses gastric cancer tumorigenesis and metastasis by inhibiting the translation of uncapped WRAP53 RNA isoforms in an m6A-dependent manner
Published 2025-01-01“…Abstract The N6-methyladenosine (m6A) modification serves as an essential epigenetic regulator in eukaryotic cells, playing a significant role in tumorigenesis and cancer progression. …”
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220
Specialized contact sites regulate the fusion of chlamydial inclusion membranes
Published 2024-10-01“…This regulatory mechanism contrasts with eukaryotic or viral fusion systems that are either composed of multiple proteins or use a change in pH to initiate membrane fusion. …”
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