Clinical Characteristics, Intraoperative Findings, and Surgical Outcomes of Canalicular Laceration Repair with Monocanalicular Stent in Asia by Chun-Hsien Lin, Chun-Yuan Wang, Ying-Cheng Shen, Li-Chen Wei

“…Single lower canaliculus was involved in 37 (77.1%) patients, upper canaliculus in 10 (20.8%) patients, and both in 1 (2.1%) patient. The most common etiology was motorcycle accident (41.7%), and all traffic accident injuries accounted for 68.75% of cases. …”
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Interventricular septal dissection secondary to acute inferior myocardial infarction: case series and literature review by Ping Chen, Xiuqin Wang, Yun Mou

“…Conclusions These two cases illustrate a complication of acute myocardial infarction and highlight the importance of echocardiography in its diagnosis. By exploring the etiology, pathogenesis, and key diagnostic points of IVSD, this study aims to provide valuable insights for clinical practice.…”
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Computer vision syndrome: neuro- and pathophysiological aspects (analytical review) by R.R. Akhmadeev, T.R. Mukhamadeev, E.R. Shammasova

“…Most studies have classi-cally focused on epidemiological and etiological aspects of CVS. This article analyses 9 national and 42 international studies on CVS with a focus on its pathogenesis. …”
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COVID-19 encephalopathy with severe neurological symptoms: a clinical case presentation with literature review by G. Baranauskienė, N. Tutlienė, G. Kaubrys

“…However, the most likely etiology of encephalopathy is multifactorial: systemic disease response, inflammation, coagulopathy, direct viral neuroinvasion, endoartheritis, and possibly post-infectious autoimmune mechanisms. …”
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Cellular and immune landscape of chronic liver diseases: insights from immunophenotyping by Shaghayegh Soleimani, Shaghayegh Soleimani, Ozgur Albayrak, Kayra Somay, Hong Yang, Buket Yigit, Burge Ulukan, Dila Atak, Murat Akyildiz, Metehan Gursoy, Elif Demirtas, Adil Mardinoglu, Adil Mardinoglu, Atay Vural, Atay Vural, Murat Dayangac, Mujdat Zeybel

“…The NK cell count was lower in peri-tumor liver specimens compared to ARLD, and an upregulation of TIGIT, an inhibitory marker, was observed in those peri-tumor specimens.ConclusionThis study contributes to the understanding of immune dynamics in chronic liver disease among different etiologies. B lymphocytes are relatively reduced in alcohol-related liver disease compared to other groups, and T cells exhibit a more differentiated subtype. …”
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Diagnostics and Treatment of Esophageal Achalasia (Clinical Guidelines of the Russian Gastroenterological Association, Russian Scientific Medical Society of Internal Medicine, Russ... by V. T. Ivashkin, A. S. Trukhmanov, I. V. Maev, O. M. Drapkina, A. I. Martynov, O. A. Storonova, E. A. Godgello, M. P. Korolev, T. L. Lapina, P. V. Pavlov, A. V. Paraskevova, I. A. Tarasova, E. D. Fedorov, A. T. Tskhovrebov, M. P. Shapka, A. L. Shestakov, A. V. Yurasov

“…Achalasia is an idiopathic neuromuscular disease manifested by a functional disorder of the patency of the cardia due to a lack of coordination between swallowing, reflex opening of the lower esophageal sphincter, and the motor and tonic activity of the smooth muscles of the esophagus. The etiology of achalasia remains unclear. However, it is believed that the key role belongs to the changes in the myenteric (Auerbach’s) intermuscular plexus of the enteric nervous system of the esophagus, leading to loss of neuronal function. …”
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Serum metabolome profiling in patients with mild cognitive impairment reveals sex differences in lipid metabolism by Rocio Diaz Escarcega, Vijay Kumar M. J., Vasilia E. Kyriakopoulos, Guadalupe J. Ortiz, Aaron M. Gusdon, Huihui Fan, Pedram Peesh, Maria P. Blasco Conesa, Gabriela Delevati Colpo, Hilda W. Ahnstedt, Lucy Couture, Stella H. Kim, Miriam Hinojosa, Christine M. Farrell, Sean P. Marrelli, Akihiko Urayama, Bhanu P. Ganesh, Paul E. Schulz, Louise D. McCullough, Andrey S. Tsvetkov

“…Overall, we identified novel sex-specific metabolites in MCI patients that could serve as biomarkers of MCI in both sexes, help further define AD etiology, and reveal new potential prevention strategies for AD.…”
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Current status of the thyroid hormone measurement items in patients receiving levothyroxine monotherapy by the management based on the thyroid tissue volume by Mitsuru Ito, Hanna Deguchi-Horiuchi, Sawako Takahashi, Mako Hisakado, Kazuyoshi Kohsaka, Eijun Nishihara, Shuji Fukata, Mitsushige Nishikawa, Akira Miyauchi, Takashi Akamizu

“…This retrospective study examined the composition of the thyroid hormone measurement items (serum-free thyroxine [FT4], FT3, and FT4 + FT3) in patients receiving LT4 monotherapy. According to the etiology of hypothyroidism, 36% of the 25,523 patients included in this study underwent total thyroidectomy (TT). …”
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Renal Transplantation Dramatically Reduces IgA Anti-beta-2-glycoprotein I Antibodies in Patients with Endstage Renal Disease by Manuel Serrano, Jose Angel Martínez-Flores, Maria José Castro, Florencio García, David Lora, Dolores Pérez, Esther Gonzalez, Estela Paz-Artal, Jose M. Morales, Antonio Serrano

“…Patients with different etiologies of ESRD showed higher levels of IgA aB2GPI than blood donors, except the groups of non-IgA glomerular disease and systemic erythematosus lupus, whose nonsignificant differences were observed. …”
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Congenital muscular dystrophies and myopathies: the leading cause of genetic muscular disorders in eleven Chinese families by Bin Mao, Xiaoling Cai, Na Lin, Yulin Jiang, Na Hao, Yifang Dai, Danhua Guo, Deqin He, Huili Xue, Lingji Chen, Qianqian He, Min Zhang, Meihuan Chen, Hailong Huang, Liangpu Xu

“…In this study, we recruited eleven families with early-onset neuromuscular disorders in China, aimed to clarify the underlying genetic etiology. Methods Essential clinical tests, such as biomedical examination, electromyography and muscle biopsy, were applied to evaluate patient phenotypes. …”
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Diagnostic ability of myxovirus resistance-A in pediatric cases of viral-acute respiratory tract infections with vitamin A and zinc deficiencies by Dian Kesumapramudya Nurputra, Amalia Setyati, Nur Arfian, Endy Paryanto Prawirohartono, Zulvikar Syambani Ulhaq

“…This cross-sectional study involved a total of 113 subjects, including 53 diagnosed with ARTI due to viral causes based on validated clinical scoring criteria, and 50 healthy controls. To determine the etiology, we conducted blood cultures and employed RT-PCR analysis on nasopharyngeal swabs. …”
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Aqueous humor metabolomic profiling identifies a distinct signature in pseudoexfoliation syndrome by Arturs Zemitis, Arturs Zemitis, Juris Vanags, Juris Vanags, Theresa Schiemer, Theresa Schiemer, Kristaps Klavins, Kristaps Klavins, Guna Laganovska, Guna Laganovska

“…PurposePEXS was first described in 1917, yet its etiology still needs clarification. An imbalance between oxidants and antioxidants plays a significant role. …”
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Association between weight-adjusted-waist index and the prevalence of gallstone disease in Minhang District, Shanghai: a cross-sectional study by Jian Wang, Zixuan Zheng, Hongyu Tan, Shan Wei, Yufeng Gu, Yingsheng Cheng, Chengyan Xu, Wei Wang

“…Abstract Background Gallstone disease (GSD) is a common and costly health issue with a multifactorial etiology linked to obesity. The Weight-Adjusted-Waist Index (WWI) is a novel anthropometric measure that incorporates both weight and waist circumference, potentially offering a better assessment of GSD risk associated with adiposity. …”
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NOD-like receptor family pyrin domain containing 3 (rs10754558) gene polymorphism in chronic spontaneous urticaria: A pilot case-control study by Aya El Gendy, Fawzia Hassan Abo Ali, Shereen A. Baioumy, Sara I. Taha, Mahy El -Bassiouny, Osama M. Abdel Latif

“…Objective: This case-control study aimed to determine the association between the NLRP3 inflammasome (rs10754558) single nucleotide polymorphism (SNP) and the occurrence, severity and etiology of CSU. Methods: Each study group included 62 participants; all were subjected to CSU severity evaluation by the urticaria activity score (UAS), autologous serum skin testing (ASST) and NLRP3 (rs10754558) genotyping. …”
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Role of Arg1+ ILC2s and ILCregs in gestational diabetes progression by Zhangyun Gong, Haixing Yi, Jie Zhang, Wan Li, Hao Wang, Peipei Guo, Caihua Li, Anan Pan, Yunxia Cao, Zhimin Lu, Huanhuan Jiang

“…Chronic low-grade inflammation leads to insulin resistance, a major etiological factor in gestational diabetes mellitus (GDM). …”
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Mathematical modeling in autoimmune diseases: from theory to clinical application by Yaroslav Ugolkov, Yaroslav Ugolkov, Yaroslav Ugolkov, Antonina Nikitich, Antonina Nikitich, Cristina Leon, Gabriel Helmlinger, Kirill Peskov, Kirill Peskov, Kirill Peskov, Kirill Peskov, Victor Sokolov, Victor Sokolov, Alina Volkova, Alina Volkova

“…The research & development (R&D) of novel therapeutic agents for the treatment of autoimmune diseases is challenged by highly complex pathogenesis and multiple etiologies of these conditions. The number of targeted therapies available on the market is limited, whereas the prevalence of autoimmune conditions in the global population continues to rise. …”
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Return to play following craniotomy for non-traumatic brain lesions by Jovanna A. Tracz, Matthew L. Farmer, Mark Hughes, Debraj Mukherjee, Paul M. Brennan

“…Conclusions: Although limited by sample size, the data provides a foundation to support development of a systematic approach to RTP decision-making following craniotomy for brain lesions of non-traumatic etiology. Future work to develop consensus guidelines will benefit from objective data about outcomes, particularly in relation to repeat imaging prior to RTP.…”
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The GWAS-MAP platform for aggregation of results of genome-wide association studies and the GWAS-MAP|homo database of 70 billion genetic associations of human traits by T. I. Shashkova, D. D. Gorev, E. D. Pakhomov, A. S. Shadrina, S. Zh. Sharapov, Y. A. Tsepilov, L. C. Karssen, Y. S. Aulchenko

“…The GWAS-MAP platform and database can be used for studying the etiology of human diseases, building predictive risk models and finding potential biomarkers and therapeutic interventions. …”
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Cerebrospinal fluid‐specific oligoclonal bands in dogs with idiopathic epilepsy by Junwei Föhr, Julia K. Prümmer, Arianna Maiolini, Eliane Marti, Ilijas Jelcic, Beatriz Vidondo, Mario Ziegler, Andrea Bathen‐Nöthen, Andrea Tipold, Holger A. Volk, Veronika M. Stein

“…In human medicine, an immune‐mediated etiology is suspected in a subset of ASM‐resistant patients with epilepsy and cerebrospinal fluid (CSF)‐specific immunoglobulin G (IgG)‐type oligoclonal bands (OCBs) have been detected. …”
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Colorectal Cancer and Polyps in Diverticulosis Patients: A 10-Year Retrospective Study in 13680 Patients by Fadi Abu Baker, Jesus Alonso Z'cruz De La Garza, Amir Mari, Abdel-Rauf Zeina, Amani Bishara, Oren Gal, Yael Kopelman

“…Shared by certain epidemiological and etiological characteristics, diverticulosis and colorectal cancer (CRC) as well as colonic polyps has long been linked. …”
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