Breast Cancer Series: Hormone Therapy by Karen C. Daily, Martha C. Monroe

“…Women who are at high risk of getting breast cancer and women who have had breast cancer may be prescribed daily oral medications to block the estrogen receptor site or decrease the production of estrogen. …”
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Breast Cancer Series: Hormone Therapy by Karen C. Daily, Martha C. Monroe

“…Women who are at high risk of getting breast cancer and women who have had breast cancer may be prescribed daily oral medications to block the estrogen receptor site or decrease the production of estrogen. …”
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Synthesis and Antitumor Activity of Novel Pyridoxine-Based Bioisosteric Analogs of trans-Stilbenes by Mikhail V. Pugachev, Thang T. N. Nguyen, Timur M. Bulatov, Roman S. Pavelyev, Alfia G. Iksanova, Oksana V. Bondar, Konstantin V. Balakin, Yurii G. Shtyrlin

“…Two compounds demonstrated high activity against the estrogen-dependent MCF-7 (breast cancer) cell line with IC50 in the range of 1.9–7.9 µM and very good selectivity for other studied normal and tumor cells, including the estrogen receptor negative MDA-MB-231 breast cancer cells. …”
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17α-Ethynyl-5α-androstane-3α, 17β-diol Treatment of MNU-Induced Mammary Cancer in Rats by Clarence N. Ahlem, James M. Frincke, Steven K. White, Christopher L. Reading, Richard J. Trauger, Rajkumar Lakshmanaswamy

“…N-methyl-N-nitrosourea (MNU) induces estrogen-dependent mammary tumors in female Lewis rats. …”
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Association between Serum Trace Elements Levels, Steroid Concentrations, and Reproductive Disorders in Ewes and Does by Derar Derar, Ahmed Ali, Tariq Almundarij, Essam Abd-Elmoniem, Tamim Alhassun, Moustafa Zeitoun

“…Ewes and goats with estrogen-dominant reproductive disorders had higher Se (P=0.01), Fe (P=0.03), and Zn (P=0.01) compared with the control group. …”
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The Anti-Inflammatory, Phytoestrogenic, and Antioxidative Role of Labisia pumila in Prevention of Postmenopausal Osteoporosis by M. E. Nadia, A. S. Nazrun, M. Norazlina, N. M. Isa, M. Norliza, S. Ima Nirwana

“…Estrogen is able to suppress production of proinflammatory cytokines such as IL-1, IL-6, IL-7, and TNF-α. …”
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Jingui Shenqi Wan alleviates bone loss induced by primary osteoporosis by inhibiting osteoblast pyroptosis by Yuwangxuan Qian, Yihe Yu, Fan Yang, Qixing Liang, Dan Xu, Jiaxiang Chen, Xueqin Hu

“…Conclusion JGSQW may effectively mitigate the progression of estrogen deficiency-induced PMOP by inhibiting the dysregulated activation of osteoblast pyroptosis.…”
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Benign Metastasizing Leiomyoma: A Rare Type of Lung Metastases—Two Case Reports and Review of the Literature by Rokana Taftaf, Sandra Starnes, Jiang Wang, Ralph Shipley, Tariq Namad, Rana Khaled, Nagla Abdel Karim

“…Additional stains, such as estrogen/progesterone receptors, may need to be done to confirm the diagnosis.…”
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MiR-155-Mediated Deregulation of GPER1 Plays an Important Role in the Gender Differences Related to Inflammatory Bowel Disease by Xiaojuan Shao, Jintao Li, Fumin Xu, Dongfeng Chen, Kaijun Liu

“…The objective of this study was to investigate the role of the estrogen receptors and miR-155 in the pathogenesis of IBD. …”
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A Mathematical Model for DNA Damage and Repair by Philip S. Crooke, Fritz F. Parl

“…In this paper, we created a combined mathematical model for the formation of DNA adducts from oxidative estrogen metabolism followed by base excision repair (BER) of these adducts. …”
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DNA methylation, histone acetylation in the regulation of memory and its modulation during aging by Padmanabh Singh, Vijay Paramanik

“…Thus, the decline of estrogen levels or imbalance of these metabolites affects gene expression and underlying brain functions. …”
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Postmenopausal Deep Infiltrating Endometriosis of the Colon: Rare Location and Novel Medical Therapy by Benjamin M. Snyder, Joseph W. Beets, Bruce A. Lessey, Samuel R. W. Horton, Gary A. Abrams

“…Instead of surgery, we prescribed a novel medical therapeutic approach using conjugated estrogen-bazedoxifene to antagonize the proliferative effects of estrogen on endometrial tissue. …”
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Labial Fusion in Childhood: Management and Treatment Strategies by Ayşe Filiz GÖKMEN KARASU, Çağlar ÇETİN

“…However if the condition results in complications such as urinary retention, recurrent urinary tract infection or vaginitis topical therapy with estrogen or bethametazone is the first treatment option. …”
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Physical activities and breast cancer: a Mendelian randomization study by Lishan Ding, Qingliang Chen, Hao Liang, Meng Shen, Ming Zheng, Zhaojun Li

“…The cases were further categorized based on estrogen receptor status into estrogen receptor-positive breast cancer (ER+ BC) and estrogen receptor-negative breast cancer (ER– BC). …”
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Progression of Luminal Breast Tumors Is Promoted by Ménage à Trois between the Inflammatory Cytokine TNFα and the Hormonal and Growth-Supporting Arms of the Tumor Microenvironment... by Polina Weitzenfeld, Nurit Meron, Tal Leibovich-Rivkin, Tsipi Meshel, Adit Ben-Baruch

“…Here, we show that together with representatives of other important arms of the tumor microenvironment, estrogen (hormonal) and EGF (growth-supporting), TNFα potently induced metastasis-related properties and functions in luminal breast tumor cells, representing the most common type of breast cancer. …”
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Labial Adhesion with Acute Urinary Retention Secondary to Vaginitis by Şenol Şentürk, Pelin Üstüner, Gülşah Balık, Mehmet Kağıtcı, Ülkü Mete Ural, Figen Kır Şahin

“…Labial adhesion occurs most often in infants and girls and is usually associated with low estrogen levels. Labial adhesion in the reproductive age group is extremely rare due to abundance of estrogen. …”
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Evaluation and diagnostic approach in patient with Perrault Syndrome by Rachael Christin Nathania, Steven Yulius Usman, Ekarini Aryasatiani

“…The rare hereditary condition Perrault Syndrome is characterized by sensorineural hearing loss (SNHL) and ovarian dysfunction 2. Cyclic estrogens and progesterone may be given to adolescents with amenorrhea to induce withdrawal bleeding and mimic the menstrual cycle.   …”
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Spontaneous Coronary Artery Dissection following Topical Hormone Replacement Therapy by Alexander L. Pan, David Fergusson, Robert Hong, Ramy A. Badawi

“…Spontaneous coronary artery dissection is a rare condition, usually presenting as an acute coronary syndrome, and is often seen in states associated with high systemic estrogen levels such as pregnancy or oral contraceptive use. …”
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Analysis of In Vitro Effects of Sex Steroids on Lymphocyte Responsiveness in Murrah Buffaloes (Bubalus bubalis) by Zahoor Ahmad Pampori, Sujata Pandita

“…Estrogen at 100 pg/mL concentration stimulating the proliferation significantly (𝑃<0.05). in all groups and had higher stimulatory effect in lymphocytes from day 10 than day 0 of estrous cycle. …”
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Epigenetics and Breast Cancers by An T. Vo, Richard M. Millis

“…Hypermethylation at the CpG islands found in estrogen response element (ERE) promoters occurs in conjunction with ligand-bonded alpha subunit estrogen receptor (Erα) dimers wherein the ligand ERα dimer complex acts as a transcription factor and binds to the ERE promoter. …”
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