Pregnancy entails a U-shaped trajectory in human brain structure linked to hormones and maternal attachment by Camila Servin-Barthet, Magdalena Martínez-García, María Paternina-Die, Luis Marcos-Vidal, Daniel Martín de Blas, Anna Soler, Olha Khymenets, Daniel Bergé, Gemma Casals, Pilar Prats, Oscar J. Pozo, Clara Pretus, Susana Carmona, Oscar Vilarroya

“…The U-shaped trajectory is predominantly linked to gestational factors, as it only presents in gestational mothers and correlates with fluctuations in estrogens over time. Finally, the mother’s mental health status mediates the relationship between postpartum GM volume recovery and maternal attachment at 6 months postpartum. …”
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Sclerosus and atrophic genital Lichen or vulvar craurosis. About a case by Graciela Caridad Cabrera Acea, Julia M. Hernández Mompié, Cynthia Gómez Cabrera

“…It was treated with local high potency steroids, conjugated estrogens and psychological support. The patient had an evident symptom improvement. …”
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Finger Length Ratios in Serbian Transsexuals by Svetlana Vujović, Srdjan Popović, Ljiljana Mrvošević Marojević, Miomira Ivović, Milina Tančić-Gajić, Miloš Stojanović, Ljiljana V. Marina, Marija Barać, Branko Barać, Milena Kovačević, Dragana Duišin, Jasmina Barišić, Miroslav L. Djordjević, Dragan Micić

“…There is evidence that the 2nd and 4th digit ratio (2D : 4D) associates negatively with prenatal testosterone and positively with estrogens. The aim was to assess the difference in 2D : 4D between female to male transsexuals (FMT) and male to female transsexuals (MFT) and controls. …”
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Effects of Zearalenone on IL-2, IL-6, and IFN-γ mRNA Levels in the Splenic Lymphocytes of Chickens by Y. C. Wang, J. L. Deng, S. W. Xu, X. Peng, Z. C. Zuo, H. M. Cui, Y. Wang, Z. H. Ren

“…Zearalenone (ZEN) is an estrogenic mycotoxin produced by several Fusarium species, which can contaminate food and feed. …”
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Effect of Quercetin on Bone Mineral Status and Markers of Bone Turnover in Retinoic Acid-Induced Osteoporosis by Oršolić Nada, Jeleč Željko, Nemrava Johann, Balta Vedran, Gregorović Gordana, Jeleč Dražen

“…Good therapeutic potential of quercetin on rat skeletal system is based partly on its antioxidant capacity and estrogenic activity.…”
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Synthesis and Experimental Validation of New PDI Inhibitors with Antiproliferative Activity by Mariateresa Badolato, Gabriele Carullo, Francesca Aiello, Antonio Garofalo

“…Besides acting as a protein folding catalyst, several evidences have suggested that PDI can bind small molecules containing, for example, a phenolic structure, which includes the estrogenic one. Increasing studies indicate that PDI is involved in both physiology and pathophysiology of cells and tissues and is involved in the survival and proliferation of different cancers. …”
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Influence of chronic ischemic disorders in the prostate on the development of benign prostatic hyperplasia by G. E. Roitberg, K. G. Mkrtchyan, N. G. Kulchenko

“…After 1.5 months, we conducted a hormonal study in all rats (n=20) — determining the concentration of androgens (testosterone, dihydrotestosterone) and estrogens (estradiol) in the blood of animals and prostate tissue.Results. …”
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Chronic Hyperglycemia Modulates Rat Osteoporotic Cortical Bone Microarchitecture into Less Fragile Structures by Cristina de Mello-Sampayo, Alaíde Alves Agripino, Duarte Stilwell, Bruno Vidal, Ana Luisa Fernando, Beatriz Silva-Lima, Maria Fátima Vaz, Helena Canhão, M. Cristina Marques

“…In this study, the effect of chronic hyperglycemia in bone turnover, morphology, and biomechanics was evaluated in female Wistar rats in the presence/absence of estrogens (ovariectomy). Animals (n=28) were divided into sham, ovariectomized (OVX), hyperglycemic (streptozotocin 40 mg/kg, single-dose i.p.…”
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The Notch Pathway in Breast Cancer Progression by Emmanuel N. Kontomanolis, Sofia Kalagasidou, Stamatia Pouliliou, Xanthoula Anthoulaki, Nikolaos Georgiou, Valentinos Papamanolis, Zacharias N. Fasoulakis

“…The cross-talk of Notch and estrogens, the effect of Notch in breast cancer stem cells formation, and the dependable Notch overexpression during breast tumorigenesis have been studied enough and undoubtedly linked to breast cancer development. …”
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Pilot-Scale Removal of Trace Steroid Hormones and Pharmaceuticals and Personal Care Products from Municipal Wastewater Using a Heterogeneous Fenton’s Catalytic Process by George Tangyie Chi, John Churchley, Katherine D. Huddersman

“…The treatment system incorporating the modified PAN catalyst/H2O2 decomposed >90% of the EDCs and >40% of PPCPs using 200 mgL−1 H2O2, 3 hr residence time. The estrogenic potency EE2-EQ was removed by 82.77%, 91.36%, and 96.13% from three different wastewater treatment plants. …”
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Ferula (Ferula elaeochytris) as a phytoestrogen: Use of Ferula in laying hens by Arda Onur Özkök, Gözde Kılınç

“…Given the results achieved, it was determined that FRP does not have a significant estrogenic effect. However, FRP can be utilized to prevent lipid oxidation and for its hypocholesterolemic effect.…”
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Optogenetic screening of MCT1 activity implicates a cluster of non-steroidal anti-inflammatory drugs (NSAIDs) as inhibitors of lactate transport. by Scott A Wegner, Hahn Kim, José L Avalos

“…Our findings show that several existing drug classes inhibit MCT1 activity, including non-steroidal estrogens, non-steroidal anti-inflammatory drugs (NSAIDs), and natural products (in total representing approximately 1% of the total library, 78 out of 6400), with a moderate affinity (IC50 1.8-21 μM). …”
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Metabolomic profile and its association with the diagnosis of prostate cancer: a systematic review by Angela Patricia Salinas Pita, Mildrey Mosquera Escudero, Eliecer Jiménez-Charris, Herney Andrés García-Perdomo

“…The metabolites of interest associated with establishing a metabolomic profile in the diagnosis of localized prostate cancer were amino acids, lipids, androgens, estrogens, nucleotides, and histidine metabolism. Conclusion Disturbances in the metabolism of fatty acids, amino acids, nucleotides, and steroid hormones were identified, suggesting the presence of localized prostate cancer. …”
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Therapeutic Implications of a Polymethoxylated Flavone, Tangeretin, in the Management of Cancer via Modulation of Different Molecular Pathways by El-Shaimaa A. Arafa, Noura T. Shurrab, Manal A. Buabeid

“…Evidence indicates that tangeretin acts through several mechanisms including growth inhibition, induction of apoptosis, autophagy, antiangiogenesis, and estrogenic-like effects. Furthermore, tangeretin works through mitigating levels of inflammatory mediators in the immune system. …”
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Impact of Age and Sex on Viral Load in Hepatitis C Virus Infection by Andrea Magri, Giulia Francesca Manfredi, Carlo Smirne, Silvia Pigni, Michela Emma Burlone, Mattia Bellan, Nicole Vercellino, Rosalba Minisini, Mario Pirisi

“…These findings are consistent with data showing that estrogens exert an antiviral effect in in vitro models of HCV. …”
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A Hyperlipidic Diet Combined with Short-Term Ovariectomy Increases Adiposity and Hyperleptinemia and Decreases Cytokine Content in Mesenteric Adipose Tissue by Nelson Inacio Pinto Neto, Maria Elizabeth Sousa Rodrigues, Ana Claudia Losinskas Hachul, Mayara Franzoi Moreno, Valter Tadeu Boldarine, Eliane Beraldi Ribeiro, Lila Missae Oyama, Claudia Maria Oller do Nascimento

“…These suggest that the absence of estrogens promotes metabolic changes that may contribute to installation of a proinflammatory process induced by a hyperlipidic diet.…”
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QbD-Driven preparation, characterization, and pharmacokinetic investigation of daidzein-l oaded nano-cargos of hydroxyapatite by Namrata Gautam, Debopriya Dutta, Saurabh Mittal, Perwez Alam, Nasr A. Emad, Mohamed H. Al-Sabri, Suraj Pal Verma, Sushama Talegaonkar

“…To confront this issue, the present research aimed to design and fabricate daidzein (DZ); a phytoestrogen-loaded hydroxyapatite nanoparticles to mimic and compensate for synthetic estrogens and biomineralization. Hypothesizing this bimodal approach, hydroxyapatite nanoparticles (HAPNPs) were synthesized using the chemical-precipitation method followed by drug loading (DZHAPNPs) via sorption. …”
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Hormones and Hormonal Anabolics: Residues in Animal Source Food, Potential Public Health Impacts, and Methods of Analysis by Belachew B. Hirpessa, Beyza H. Ulusoy, Canan Hecer

“…Hormones such as steroidal (estrogens, gestagens, and androgens), nonsteroidal, semisynthetic, and synthetic or designer drugs are all growth-promoting and body-partitioning agents. …”
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Therapeutic role of isoflavones from traditional medicine in the management of polycystic ovary syndrome by Ashwini Armarkar, Prafulla Sabale, Satyendra Prasad, Vidya Sabale, Lata Potey, Dipti Masram

“…These secondary plant metabolites, which predominantly occur in the Fabaceae family, exhibit structural similarities to 17β-estradiol, and typically exist in conjugated forms. The estrogenic properties of isoflavone phytoconstituents, such as genistein, biochanin A, daidzein, puerarin, and formononetin, confer substantial therapeutic potential for PCOS management. …”
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Dry eye disease and its treatment in women over 45 years by E.A. Drozdova, V.E. Balan

“…In addition to age-related alterations of structures producing tear film, the reduction of androgen levels and other regulating hormones is important for DED development. The role of estrogens and progesterone in the regulation of lacrimal and meibomian gland activity is still disputable. …”
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