Proteolytic Processing of CD44 and Its Implications in Cancer by Priscila Anhel Medrano-González, Osmar Rivera-Ramírez, Luis Felipe Montaño, Erika P. Rendón-Huerta

“…These include the protooncogene tyrosine-protein kinase Src (c-Src)/signal transducer and activator of transcription 3 (STAT3), the epithelial growth factor receptor, the estrogen receptor, Wnt/βcatenin, or Hippo signaling pathways all of which are associated to cell proliferation, differentiation, or cancer progression. …”
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Efficient sex hormone biosensors in Saccharomyces cerevisiae cells to evaluate human aromatase activity and inhibition by Jie Wu, Matthias Bureik, Mario Andrea Marchisio

“…We engineered compact β-estradiol biosensors in S. cerevisiae cells by leveraging short (20-nt long) operators bound by the fusion protein LexA-ER-VP64—where ER is the human estrogen receptor and VP64 a strong viral activation domain. …”
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Exploring the role of ESR1 mutations in metastatic hormone receptor-positive breast cancer T cell immune surveillance disruption by Morgane Lopez, Laurie Spehner, Fabrice André, Julien Viot, Evan Seffar, Amélie Marguier, Elsa Curtit, Guillaume Meynard, Erion Dobi, Sylvain Ladoire, Romain Boidot, Romain Loyon, Valentin Derangere, François-Clément Bidard, Christophe Borg, Laura Mansi, Marie Kroemer

“…In 40% of cases, a key mechanism of endocrine resistance to the standard first line is a mutation of the ligand-binding domain (LBD) of Estrogen Receptor 1 (ESR1) encoding estrogen receptor α (ER). …”
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Transformer-based modeling of Clonal Selection and Expression Dynamics reveals resistance mechanisms in breast cancer by Nathan D Maulding, Jun Zou, Wei Zhou, Ciara Metcalfe, Joshua M Stuart, Xin Ye, Marc Hafner

“…When applied to cells treated with either giredestrant, a selective estrogen receptor (ER) antagonist and degrader, or palbociclib, a CDK4/6 inhibitor, pathways dynamically associated with resistance are revealed. …”
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The mechanism underlying metastasis in triple-negative breast cancer: focusing on the interplay between ferroptosis, epithelial-mesenchymal transition, and non-coding RNAs by Ziyi Chen, Yi Zhao, Yi Zhao

“…Triple-negative breast cancer (TNBC) is a type of breast cancer with lack the expression of estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2). …”
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The Immunoexpression of Glucocorticoid Receptors in Breast Carcinomas, Lactational Change, and Normal Breast Epithelium and Its Possible Role in Mammary Carcinogenesis by Raja Alyusuf, Javed Fayyaz Wazir, Urmil Prabha Brahmi, Abdul Rahman Fakhro, Moiz Bakhiet

“…The role of estrogen and progesterone receptors in breast cancer biology is well established. …”
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Pregnancy Followed by Delivery May Affect Circulating Soluble Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 Levels in Women of Reproductive Age by Mehmet Balin, Ahmet Çelik, M. Ali Kobat, Adil Baydas

“…It is known that menopause or lack of endogenous estrogen is a risk factor for endothelial dysfunction and CAD. …”
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Impact of Vitamin D on Skin Aging, and Age-Related Dermatological Conditions by Sankalya S. Ambagaspitiya, Gayan A. Appuhamillage, Sunil J. Wimalawansa

“…Intrinsic factors associated with advanced age gradually degrade the dermal collagen matrix, resulting in fine wrinkles and reduced elasticity; this is accelerated in post-menopausal women due to estrogen deficiency. In contrast, extrinsic factors associated with advanced age, primarily caused by exposure to ultraviolet (UV) radiation, lead to coarse wrinkles, solar elastosis, hyperkeratosis, irregular pigmentation, and skin cancers. …”
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Risk Factors for Hypertension in Women of Childbearing Age by Natasya Vidia, Betty Yosephin Simanjuntak, Diah Eka Nugraheni

“…Hormonal contraceptives contain the hormones estrogen and progesterone, resulting in a hormonal imbalance that leads to hypertension. …”
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Association between Single Nucleotide Polymorphisms rs3757318 and Vitamin D Deficiency in Iraqi Breast Cancer Patients by Istikrar M. Hade, Ahmed S. K. Al-Khafaji, Fadhel M. Lafta, Yasir B. Qaddoori

“…Background: Multiple single-nucleotide polymorphisms (SNPs) located in the intergenic region between estrogen receptor 1 and CCDC170 (especially at rs3757318) are thought to be associated with breast cancer risk. additionally, the serum level of vitamin D is believed to be linked to different aspects of breast carcinogenesis. …”
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In Silico, In Vitro, and In Vivo Wound Healing Activity of Astragalus microcephalus Willd. by Fatemeh Akbari, Mohammad Azadbakht, Ali Bagheri, Lale Vahedi

“…In silico examination was performed based on the LC/MS results, and the binding affinity of these compounds to estrogen receptors (ERs) α and β was evaluated. Wound healing evaluation in both in vitro (NHDF cell line, by 500 μg/ml concentration of the extract, 24 h) and in vivo (Wistar rat, topical daily treated with 1.5% of the extract ointment, 21 days) conditions in comparison to control groups was conducted. …”
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Endometriosis in Postmenopausal Woman Without Previous Hormonal Therapy: A Case Report by Mine İslimye Taşkın, Meltem Çağrı Menteşe, Engin Uzgören, Ümit İnceboz

“… Endometriosis is a benign, estrogen-dependent, chronic gynecological disorder commonly associated with pelvic pain and infertility. …”
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Insulin-Like Growth Factor and Epidermal Growth Factor Signaling in Breast Cancer Cell Growth: Focus on Endocrine Resistant Disease by Kallirroi Voudouri, Aikaterini Berdiaki, Maria Tzardi, George N. Tzanakakis, Dragana Nikitovic

“…Numerous studies have demonstrated that both estrogens and growth factors stimulate the proliferation of steroid-dependent tumor cells, and that the interaction between these signaling pathways occurs at several levels. …”
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Breast Cancer Treatment Practices in Elderly Women in a Community Hospital by Hua Wang, Awinder P. Singh, Serena A. St. Luce, Alan R. Go

“…Eighty-six percent of patients who were estrogen receptor-positive received adjuvant hormonal therapy. …”
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Axillary Metastasis from an Occult Tubal Serous Carcinoma in a Patient with Ipsilateral Breast Carcinoma: A Potential Diagnostic Pitfall by Chantal Atallah, Gulbeyaz Altinel, Lili Fu, Jocelyne Arseneau, Atilla Omeroglu

“…In this context, the poorly differentiated appearance of the metastatic tumor and positive staining for estrogen receptor, might lead to a misdiagnosis of metastatic breast carcinoma. …”
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Evaluation of Salivary and Serum Total Antioxidant Capacity and Lipid Peroxidation in Postmenopausal Women by Fatemeh Zovari, Hadi Parsian, Ali Bijani, Ameneh Moslemnezhad, Atena Shirzad

“…In menopause, reduction of estrogen hormone affects oxidative stress process in serum. …”
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Immunotherapeutic Approaches in Triple-Negative Breast Cancer: State of the Art and Future Perspectives by Karima Oualla, Loay Kassem, Lamiae Nouiakh, Lamiae Amaadour, Zineb Benbrahim, Samia Arifi, Nawfel Mellas

“…Triple-negative breast cancer (TNBC) is characterized by the absence of estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2). …”
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CD4+T and CD8+T Cells in Uterus Exhibit Both Selective Dysfunction and Residency Signatures by Shuangpeng Kang, Shuiping Jin, Xueying Mao, BinSheng He, Changyou Wu

“…Our previous study fully elucidated the characteristics of γδT cells in nonpregnant uterus and the mechanism modulated by estrogen. However, comprehensive knowledge of the immunological properties of αβT (including CD4+T cells and CD8+T) cells in nonpregnancy uterus has not been acquired. …”
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Associations of Polyunsaturated Fatty Acid Intake with Bone Mineral Density in Postmenopausal Women by Margaret Harris, Vanessa Farrell, Linda Houtkooper, Scott Going, Timothy Lohman

“…A secondary analysis of cross-sectional data was analyzed from 6 cohorts (Fall 1995–Fall 1997) of postmenopausal women (n=266; 56.6±4.7 years) participating in the Bone Estrogen Strength Training (BEST) study (a 12-month, block-randomized, clinical trial). …”
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Prenatal exposure to nitrate alters uterine morphology and gene expression in adult female F1 generation rats by André Gilberto Cassiani, Thiago Pinheiro Arrais Aloia, Érica Kássia Sousa-Vidal, Sérgio Podgaec, Carla de Azevedo Piccinato, Caroline Serrano-Nascimento

“…Additionally, nitrate treatment significantly increased the expression of estrogen receptors and reduced the expression of progesterone receptors in the uterus. …”
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