Evaluation of pulmonary tuberculosis disease burden in Shenyang, China, 2023 by Huijie Chen, Haiyan Bi, Peng Li, Zhixing Yang, Lihai Wen, Baijun Sun, Wei Sun

“…Methods The disability-adjusted life years (DALYs) calculated based on Global Burden of Disease (GBD) framework was used to assess the disease burden of PTB in Shenyang in 2023, and descriptive epidemiological methods were employed to elucidate the magnitude, composition, and distribution characteristics of PTB disease burden in Shenyang. …”
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Preoperative prediction of IDH genotypes and prognosis in adult-type diffuse gliomas: intratumor heterogeneity habitat analysis using dynamic contrast-enhanced MRI and diffusion-we... by Xingrui Wang, Zhenhui Xie, Xiaoqing Wang, Yang Song, Shiteng Suo, Yan Ren, Wentao Hu, Yi Zhu, Mengqiu Cao, Yan Zhou

“…Conclusions Habitat imaging employing DCE-MRI and DWI may facilitate the characterization of ITH in adult-type diffuse gliomas and serve as a valuable adjunct in the preoperative prediction of IDH genotypes and prognosis. …”
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Non-small Cell Lung Cancer Cell Line PC-9 Drug-resistant Mutant Cell Line 
Establishment and Validation of Their Sensitivity to EGFR Inhibitors by Tao HU, Yang LOU, Mingbo SU

“…Methods Clustered regularly interspaced short palindromic repeats/CRISPR-associated nuclease 9 (CRISPR/Cas9) technology was employed to knock in the EGFRT790M/C797S mutant fragment into NSCLC PC-9 cells, originally harboring the EGFRD19 mutation, to generate the PC-9 EGFRD19/T790M/C797S cell model. …”
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Effects of oil pollution on the growth and rhizosphere microbial community of Calamagrostis epigejos by Ying Wei, Yukun Zhu, Liqun Yang, Chen Chen, Ming Yue, Zhuxin Mao, Yuchao Wang, Qian Li, Yang Li, Jinlin Lv, Wenyan Xue

“…Metagenomic sequencing technology was employed to analyze the community structure and diversity of soil bacteria, fungi, archaea, and viruses. …”
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Risk prediction models for feeding intolerance in patients with enteral nutrition: a systematic review and meta-analysis by Huijiao Chen, Jin Han, Jing Li, Jianhua Xiong, Dong Wang, Mingming Han, Yuehao Shen, Wenli Lu

“…In the field of model construction, only one study employed the use of multiple machine-learning techniques for the development of a model. …”
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Soil moisture partitioning strategies in blowouts in the Hulunbeier grassland and response to rainfall by Zhixin Bao, Limin Yuan, Limin Yuan, Limin Yuan, Zhongju Meng, Ezhen Zhang, Lei Zhu, Jinwang Liu

“…Understanding the dynamic change characteristics of soil moisture in blowouts and soil water retention capacity is of great significance for the management of blowouts.MethodsThis study employs drying and in situ monitoring methods to select typical blowouts in different regions (sand pits, fringe zones, sand accumulation zones, and sand-grass transition zones) on the Hulunbuir Grassland. …”
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Exploring the clinical value of procalcitonin, c-reactive protein, white blood cell count, and neutrophil-to-lymphocyte ratio in the early diagnosis of bloodstream infections in ch... by Yadong Li, Mingjie Li, Chenye Lin, Wentao Tang, Qiuyu Tang, Feng Cheng

“…Moreover, the study employed the receiver operating characteristic (ROC) curve to evaluate the diagnostic value of these indicators in identifying BSI in pediatric patients at an early stage. …”
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Influencing factors of the participation of patients with severe mental disorders in community health service management by Shiming Li, Yingying Ji, Queping Yang, Ying Jiang, Qitao Yin, Haohao Zhu

“…Logistic regression modeling will be employed to identify influencing factors. Ultimately, negative factors affecting participation in community health management will be identified, followed by targeted qualitative analysis through interviews.ResultsA total of 27,977 individuals were included in the analysis, with 25,744 participants enrolled in community health service management, resulting in a management rate of 92.02%. …”
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α-Methyl-Tryptophan Inhibits SLC6A14 Expression and Exhibits Immunomodulatory Effects in Crohn’s Disease by Su Y, Li J, Chen Y, Bao J, Lei Z, Ma M, Zhang W, Liu Q, Xu B, Hu T, Hu Y

“…Traditional diagnostic and therapeutic methods have limitations, necessitating the exploration of more effective strategies.Methods: In this study, we employed the Gene Expression Omnibus database to identify genes that are differentially expressed in CD. …”
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Global burden of subarachnoid hemorrhage among adolescents and young adults aged 15-39 years: A trend analysis study from 1990 to 2021. by Xuanchen Liu, Rui Cheng, Yingda Song, Xiaoxiong Yang, Xiaochen Niu, Chunhong Wang, Guijun Jia, Hongming Ji

“…Statistical analyses, including Joinpoint regression and decomposition analysis, were employed to assess temporal trends and the impact of population growth, aging, and epidemiological changes.…”
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Targeted reproductive management for lactating Holstein cows: Economic return by Ricardo C. Chebel, Tomas Gonzalez, Ana B. Montevecchio, Klibs N. Galvão, Albert de Vries, Rafael S. Bisinotto

“…ABSTRACT: Targeted reproductive management (TRM), employing automated monitoring devices (AMD), is as an alternative to the blanket adoption of ovulation synchronization protocols (OvSP) for first postpartum AI and a means of reducing the use of OvSP for re-insemination of nonpregnant cows. …”
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A Novel Unilateral Bi/Multi‐Portal Endoscopic Transforaminal Interbody Fusion Utilizing Uniaxial Spinal Endoscope Instead of Arthroscope: Technical Note and Preliminary Clinical Re... by Liyu Yang, Long Zhou, Min Qiu, Feng Liang, Liqing Yang, Qin Fu, Gen Ba

“…ABSTRACT Background Currently, traditional UBE surgery, which is based on arthroscope, has been increasingly employed for complex lumbar degenerative diseases. …”
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Early Detection and Intervention of Preschool-Aged Children Using Android-Based Monitoring during the COVID-19 Pandemic in Central Java by Triwiji Lestari, Elisa

“…This study aims to assess the effectiveness of an Android-based early detection and intervention system on the development of preschool children during the challenging circumstances of the COVID-19 pandemic in Central Java. The research employed a quasi-experimental design without a control group using a range of instruments, including observation sheets, the Sahabat Bunda application, the pre-screening developmental questionnaire (PDQ), and anthropometric measurements. …”
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Integrated Effects of Water and Nitrogen Coupling on Eggplant Productivity, Fruit Quality, and Resource Use Efficiency in a Cold and Arid Environment by Jie Li, Hengjia Zhang, Chenli Zhou, Anguo Teng, Lian Lei, Yuchun Ba, Jiandong Yu, Fuqiang Li

“…The W₂N₂ treatment had the maximum water use efficiency and irrigation water use efficiency, which were significantly higher than other water and nitrogen application treatments and CK by 14.79–42.51% in 2022 and 8.79–44.88% in 2023, and 15.86–45.55% in 2022 and 4.68–40.22% in 2023, respectively. By employing the EWM-TOPSIS model for comprehensive evaluation, the results indicated that mild water deficit (60–70% in FC) and moderate nitrogen application (270 kg·ha⁻¹) at flowering and fruiting of eggplants was the optimal water and nitrogen application mode under mulched drip irrigation in the Hexi region of northwest China. …”
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Anticancer Activity of Asiatic Acid from Centella Asiatica: A Comprehensive Systematic Review of In Vitro and In Vivo Studies by Fiki Muhammad Ridho, Panggih Fahrudin, Andika Julyanto Syachputra, Iren Angelia Aruan, Kamailiya Ulfah, Alfi Syahri

“…A systematic review method was employed and several databases, including Scopus, PubMed, ScienceDirect, and Google Scholar, were used to conduct a comprehensive and systematic search of the literature based in vitro and in vivo studies in November 2023 following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. …”
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Potential drug targets for asthma identified through mendelian randomization analysis by Xingxuan Chen, Yu Shang, Danting Shen, Si Shi, Zhe Wen, Lijuan Li, Hong Chen

“…Bidirectional Mendelian randomization analysis, Steiger filtering, colocalization, and phenotype scanning were employed for reverse causal inference detection, further substantiating the Mendelian randomization results. …”
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Identifying the Antecedents of Employee Perceptions of Human Resource Practices Using Signaling Theory by Aryan Gholipour, Mohammad Abooyee Ardakan, Neda Mohammad Esmaeili, Atiyeh Rasouli

“…The main goal of this research was to identify the drivers, antecedents, or elements that significantly influence the formation of employee perceptions of HR practices Methods  To conduct the present research, a systematic literature review (SLR) method was employed. Using keywords related to employee perceptions of human resources, approximately 1,000 articles from 2004 to 2022 were identified and reviewed. …”
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Geographic variation in modern contraceptive utilization among women of reproductive age in Mozambique: a multilevel analysis by Habtu Kifle Negash, Destaye Tirite Gelaw, Mihret Getnet, Hiwot Tezera Endale, Tseganesh Asefa, Fethiya Seid Hasen, Yihun Tefera Ayenew, Nebebe Demis Baykemagn, Trualem Zeleke Yehuala, Winta Tesfaye

“…Data analysis was conducted using Stata 17 and ArcGIS 10.7, employing multilevel logistic regression and spatial techniques (Global Moran’s I, Getis-Ord Gi*, interpolation, and SaTScan) to identify patterns and geographic clusters of contraceptive use. …”
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Loss of histone H3K27me3 up-regulates SLC7A11 in diffuse gastric cancer cells by REN Yuanfeng, LIU Wenkang, CHU Zhaole

“…Cleavage under target and tagmentation （CUT&Tag） technology was employed to capture genomic regions modified by H3K27me3， and analyze the reprogramming characteristics of these modifications. …”
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Injectable Nanocomposite Hydrogel for Accelerating Diabetic Wound Healing Through Inflammatory Microenvironment Regulation by Chen Y, Li Y, Song H, Liu X, Zhang H, Jiang J, Liu H, Zhuo R, Cheng G, Fang J, Xu L, Qi Y, Sun D

“…Yuhui Chen,1,* Ying Li,1,* Haoning Song,1,* Xiaochun Liu,1 Hongan Zhang,1 Jiaxin Jiang,2 Hongsheng Liu,2 Ribo Zhuo,1 Guoyun Cheng,1 Jia Fang,1 Lei Xu,1 Yong Qi,1 Dawei Sun1 1Department of Orthopedics and Traumatology, The Affiliated Guangdong second Provincial General Hospital of Jinan University, Guangzhou, Guangdong, 510315, People’s Republic of China; 2Guangdong Huayi Biomedical Science and Technology Center, Guangzhou, Guangdong, 511450, People’s Republic of China*These authors contributed equally to this workCorrespondence: Lei Xu, Department of Orthopedics and Traumatology, Guangdong second Provincial General Hospital of Jinan University, No. 466 Xingang Middle Road, Haizhu District, Guangzhou, Guangdong, People’s Republic of China, Email orthoxl@163.com Dawei Sun, Department of Orthopedics and Traumatology, Guangdong second Provincial General Hospital of Jinan University, No. 466 Xingang Middle Road, Haizhu District, Guangzhou, Guangdong, People’s Republic of China, Email sundw@gd2h.org.cnBackground: A paramount issue in the realm of chronic wound healing among diabetic patients is the pervasive inflammatory response that persistently thwarts angiogenesis, thereby precipitating protracted delays in the healing process of such wounds. Employing zeolitic imidazolate framework-8 (ZIF-8) as a drug delivery platform, integrated within a temperature-sensitive injectable hydrogel, presents an intriguing strategy for the closure of various irregular wounds, modulation of inflammatory responses, and promotion of angiogenesis.Methods: Herein, ZIF-8 loaded with curcumin (Cur) combined with methylcellulose/carboxymethyl chitosan (MCC) thermosensitive hydrogel was described. …”
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