Prognostic significance of albumin corrected anion gap in patients with acute pancreatitis: a novel perspective by Jianjun Wang, Pei Yang, Xintao Zeng, Sirui Chen, Xi Chen, Lan Deng, Ruizi Shi, Chuan Qin, Huiwen Luo, Jianping Gong, Hua Luo, Decai Wang

“…Kaplan-Meier survival curves and multivariate Cox proportional hazards regression models were employed to assess the association between ACAG and short- and long-term ACM of AP. …”
Get full text

Technical efficiency of public hospitals in east Africa: a systematic review and meta-analysis by Anteneh Lamesgen, Bekalu Endalew, Aysheshim Belaineh Haimanot, Tigabu Kidie Tesfie, Elyas Melaku Mazengia, Mulat Belay Simegn, Werkneh Melkie Tilahun, Molla Yigzaw Birhanu, Lakew Asmare, Habtamu Geremew, Muluye Gebrie Mengie

“…Methods A systematic search of published articles on the technical efficiency of public hospitals was employed using Pubmed, Cochrane library, and google scholar and thirteen studies were included to this review. …”
Get full text

Outcomes in Catheter Ablation of Sustained Ventricular Tachycardia in Myocarditis Compared with Ischemic Heart Disease by Sheng Su, Le Li, Xi Peng, Likun Zhou, Zhuxin Zhang, Yulong Xiong, Zhenhao Zhang, Mengtong Xu, Yan Yao

“…Initially, an endocardial approach was employed, reserving epicardial ablation procedures for non-responders. …”
Get full text

PMAIP1 regulates the progression of follicular thyroid carcinoma through the Wnt3/FOSL1 pathway by Haobo Wang, Fangjian Shang, Yifang Wang, Bo Pang, Bo Pang, Longfei Kang, Longfei Kang, Chuanmin Zhou, Chuanmin Zhou, Dongyun Li, Dongyun Li, Zhongxin Li, Zhongxin Li, Xia Jiang, Xia Jiang, Bo Liu, Zengren Zhao

“…Additionally, transcriptome sequencing was employed to identify potential signaling pathways associated with PMAIP1. …”
Get full text

Hydrocarbon generation, expulsion, and retention characteristics of the Permian Fengcheng shale and Lucaogou shale in the Junggar Basin: implications for the exploration of lacustr... by Wenjun He, Zhiming Li, Zhiming Li, Zhiming Li, Changrong Li, Changrong Li, Jinyi He, Jinyi He, Jinyi He, Junying Leng, Junying Leng, Junying Leng, Zhongliang Sun, Zhongliang Sun, Zhongliang Sun, Deguang Liu, Sen Yang

“…Additionally, a multivariate regression model was employed to systematically evaluate the primary controlling factors of hydrocarbon expulsion ratio. …”
Get full text

Unveiling the Cosmic Chemistry: Revisiting the Mass–Metallicity Relation with JWST/NIRSpec at 4 < z < 10 by Arnab Sarkar, Priyanka Chakraborty, Mark Vogelsberger, Michael McDonald, Paul Torrey, Alex M. Garcia, Gourav Khullar, Gary J. Ferland, William Forman, Scott Wolk, Benjamin Schneider, Mark Bautz, Eric Miller, Catherine Grant, John ZuHone

“…We present star formation rates (SFRs), the mass–metallicity relation (MZR), and the SFR-dependent MZR across redshifts 4–10 using 81 star-forming galaxies observed by the JWST NIRSpec employing both low-resolution PRISM and medium-resolution gratings, including galaxies from the JWST Advanced Deep Extragalactic Survey (JADES) GOODS-N and GOODS-S fields, the JWST-PRIMAL Legacy Survey, and additional galaxies from the literature in the A2744, SMACS-0723, RXJ2129, BDF, COSMOS, and MACS1149 fields. …”
Get full text

The diagnostic performance of International Ovarian Tumor Analysis: Simple Rules for diagnosing ovarian tumors—a systematic review and meta-analysis by Awadia Gareeballah, Moawia Gameraddin, Moawia Gameraddin, Sultan Abdulwadoud Alshoabi, Amirah Alsaedi, Maisa Elzaki, Walaa Alsharif, Ibrahim Mohamed Daoud, Ibrahim Mohamed Daoud, Shrooq Aldahery, Magbool Alelyani, Elrashed AbdElrahim, Fahad H. Alhazmi, Zuhal Y. Hamd, Raga Ahmed Abouraida, Mayeen Uddin Khandaker, Mayeen Uddin Khandaker, Mayeen Uddin Khandaker, Mohamed Adam

“…The terminologies “IOTA-SR”, “adnexal, mass”, and “ovarian tumors scoring” were employed. Twenty-seven research articles conducted from 2008 to 2022 were included in the meta-analysis; the publication outcome indicates that performance quality tests were extracted directly or indirectly, including true positive (TP), false positive (FP), true negative (TN), and false negative (FN). …”
Get full text

Response of alcohol fermentation strains, mixed fermentation and extremozymes interactions on wine flavor by Ling-Zhi Zhao, Ling-Zhi Zhao, Jing Chen, Jing Chen, Jing Chen, Xiang-Ying Wei, Xiang-Ying Wei, Xiang-Ying Wei, Bo Lin, Feng-Jin Zheng, Krishan K. Verma, Gan-Lin Chen, Gan-Lin Chen, Gan-Lin Chen

“…However, the use of mixed fermentation and extremozymes can provide significant insight and potential remedial solutions to overcome these technical problems and shape the final product in more desirable and sustainable ways, challenging the current shortcomings to deliver a more resilient end-products with consistent, flavorful, and a number of what may be considered remedial techniques can be employed to produce an acceptable product to consumers.…”
Get full text

Quality Evaluation of Fresh Cayenne Pepper for Chili Sauce from Different Origins by Jinge XU, Zhuoqi ZHENG, Pengjie HOU, Gaoxing MA, Yandi XIONG, Zhuang MA, Meng LIU, Liang ZHAO, Xiaojun LIAO

“…Methods: Targeted detection combined with non-targeted metabolomics technology were employed to conduct the quality evaluation on cayenne pepper from Jiuquan City, Gansu Province and Bayannur City, Inner Mongolia Autonomous Region. …”
Get full text

Associations between hypovitaminosis D, adiposity indices and insulin resistance in adolescents: mediation analyses from NHANES 2011–2018 by Yaping Deng, Yingting Luo, Yilei Shen, Yong Zhao, Wei Cao, Jie Cao, Lijuan Xu, Lin Kong

“…Methods We conducted a comprehensive analysis of NHANES data from 2011 to 2018, examining the correlation between adiposity indices such as Body Mass Index (BMI), Fat Mass Index (FMI, defined as the ratio of fat mass to height squared), hypovitaminosis D, and IR. We employed the XGBoost algorithm to identify key factors significantly influencing IR, thereby deepening our insight into the link between adiposity and insulin resistance. …”
Get full text

LoCS-Net: Localizing convolutional spiking neural network for fast visual place recognition by Ugur Akcal, Ugur Akcal, Ugur Akcal, Ivan Georgiev Raikov, Ekaterina Dmitrievna Gribkova, Ekaterina Dmitrievna Gribkova, Anwesa Choudhuri, Anwesa Choudhuri, Seung Hyun Kim, Mattia Gazzola, Rhanor Gillette, Rhanor Gillette, Ivan Soltesz, Girish Chowdhary, Girish Chowdhary, Girish Chowdhary

“…Rate-based approximations of leaky integrate-and-fire (LIF) neurons are employed during training, which are then replaced with spiking LIF neurons during inference. …”
Get full text

Analysis of the risk of oncological adverse events associated with infliximab in combination with azathioprine compared to monotherapy: insights from the FAERS database by Qian Qiao, Qian Qiao, Qian Qiao, Jiachen Sun, Jiachen Sun, Jiachen Sun, Ya Zheng, Ya Zheng, Yingying Mi, Yingying Mi, Yingying Mi, Yanan Gong, Yanan Gong, Jiahui Liu, Jiahui Liu, Jiahui Liu, Wenyue Rui, Wenyue Rui, Wenyue Rui, Yumei Ma, Yumei Ma, Yumei Ma, Yongning Zhou, Yongning Zhou, Min Liu, Min Liu

“…ObjectiveThis study aimed to evaluate the risk of tumor formation with infliximab or azathioprine monotherapy versus their combination, using the FDA Adverse Event Reporting System (FAERS) database.MethodsData were extracted from the FAERS database for patients treated with infliximab, azathioprine, and combination therapy from Q1 2004 to Q2 2024. Signal mining employed methods such as Reported Odds Ratio (ROR), Proportional Reporting Ratio (PRR), Multiple Gamma-Poisson Scaling Assessment (MGPSA) and Bayesian Confidence Interval Progressive Neural Network (BCPNN).ResultsOur analysis of the FAERS database revealed that the highest number of reported cases involved skin-related tumors, both individually and in combination. …”
Get full text

Mesenchymal Stem Cells Carrying Viral Fusogenic Protein p14 to Treat Solid Tumors by Inducing Cell–Cell Fusion and Immune Activation by Yao Wang, Xunlei Pang, Ruirui Li, Jiuzhou Chen, Chen Wen, Huihuang Zhu, Tingyu Long, Jianjie Li, Lijun Zheng, Youcai Deng, Junnian Zheng, Bo Xu

“…Cell viability assay was employed to assess the killing effects of MSCs carrying the p14 protein (MSCs-p14), which was also identified in the subcutaneous tumor models. …”
Get full text

Evolution paths of urban forms influenced by landforms: Asynchrony but convergence by Chao Yang, Qiyan Huang, Qiong Xian, Meng Yuan, Xiaoming Cong, Lisha Xun, Jianxiong Cheng, Hongyi Pan

“…Principal component analysis and hierarchical clustering are then employed to classify urban form types, revealing evolution patterns and trends across various landforms. …”
Get full text

Alcohol intake exacerbates experimental autoimmune prostatitis through activating PI3K/AKT/mTOR pathway-mediated Th1 differentiation by Shun Xu, Shun Xu, Shun Xu, Jing Chen, Jing Chen, Jing Chen, Shaoyu Yue, Shaoyu Yue, Shaoyu Yue, Yifan Zhang, Yifan Zhang, Yifan Zhang, Shengyu Zhao, Shengyu Zhao, Shengyu Zhao, Yongtao Hu, Yongtao Hu, Yongtao Hu, Cheng Zhang, Cheng Zhang, Cheng Zhang, Wenrui Guan, Wenrui Guan, Wenrui Guan, Li Zhang, Li Zhang, Li Zhang, Ligang Zhang, Ligang Zhang, Ligang Zhang, Chaozhao Liang, Chaozhao Liang, Chaozhao Liang

“…The HE staining, ELISA, and behavioral experiments were employed to assess the severity of inflammation in EAP mice and EAP-alcohol mice. …”
Get full text

The novel manualized RELIEVE-group treatment for burdened relatives of cancer patients: a feasibility study by Jessica Neumann, Jessica Neumann, Jil Beckord, Jil Beckord, Helen Samira Hesse, Helen Samira Hesse, Carl Martin, Carl Martin, Carlotta Mons, Carlotta Mons, Diana Chur, Diana Chur, Jörg Hense, Jörg Hense, Mitra Tewes, Martin Teufel, Martin Teufel, Eva-Maria Skoda, Eva-Maria Skoda

“…A paired samples T-test was employed to assess the feasibility of the treatment, with pre- and post-scores being compared. …”
Get full text

A stratified two-stage tumor molecular profiling algorithm to identify clinically actionable molecular alterations in pancreatic cancer☆ by S. Hussung, D. Akhoundova, C. Pistoni, D. Lenggenhager, A. Töpfer, C. Pauli, B. Pestalozzi, C. Britschgi, M. Zoche, M. Rechsteiner, H. Moch, A. Weber, R. Fritsch

“…Stage 1 comprised immunohistochemistry for mismatch repair deficiency and targeted sequencing employing a 33-gene next-generation sequencing panel covering common PC drivers and DNA damage response genes. …”
Get full text

YWHAG promotes bladder cancer metastasis by regulating TMOD3 to activate ERK1/2 and JNK phosphorylation in the MAPK pathway by Tai Tian, Shiming He, Han Hao, Bao Guan, Yanqing Gong, Jian Fan, Zhenpeng Zhu, Wenzhi Gao, Yucai Wu, Ninghan Feng, Aixiang Wang, Yuexian Guo, Xuesong Li

“…Transcriptome sequencing was employed to identify the key signaling pathways regulated by YWHAG. …”
Get full text

Leveraging Autofluorescence for Tumor Detection, Diagnosis, and Accurate Excision with Surgical Margin Assessment in Tumor Excision by Antonis Perdiou, Ramona Dumitrescu, Daniela Jumanca, Octavia Balean, Ruxandra Sava-Rosianu, Serban Talpos, Dacian Virgil Lalescu, Atena Galuscan

“…Autofluorescence imaging was performed using the OralID device, which employs a 405 nm excitation laser to detect abnormal tissue. …”
Get full text

Considerations for determining warm-water coral reef tipping points by P. Pearce-Kelly, A. H. Altieri, J. F. Bruno, C. E. Cornwall, M. McField, A. I. Muñiz-Castillo, J. Rocha, R. O. Setter, C. Sheppard, R. M. Roman-Cuesta, C. Yesson

“…Uncertainties around tipping points for such crucially important ecosystems underline the imperative of robust assessment and, in the case of knowledge gaps, employing a precautionary principle favouring lower-range tipping point values.…”
Get full text