Is there a risk of esketamine misuse in clinical practice? by Carlos Roncero, Milton Merizalde-Torres, Néstor Szerman, Marta Torrens, Pablo Vega, Pilar Andres-Olivera, Francisco Javier Álvarez

“…Therapeutic Advances in Drug Safety…”
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Overlapping of DRESS and Stevens-Johnson syndrome due to first-line antituberculosis drugs: a case report by Cristian Morán-Mariños, Felix Llanos-Tejada, Rebeca Huamani-Llantoy, Capriny Bernal-Turpo, Kimberly López-Pilco, Alex Ventura-Leon, Renato Casanova-Mendoza

“…Therapeutic Advances in Drug Safety…”
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Unveiling unexpected adverse events: post-marketing safety surveillance of gilteritinib and midostaurin from the FDA Adverse Event Reporting database by Tingting Jiang, Yanping Li, Ni Zhang, Lanlan Gan, Hui Su, Guiyuan Xiang, Yuanlin Wu, Yao Liu

“…Therapeutic Advances in Drug Safety…”
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Integrating environmental effects in the benefit-risk assessment of therapeutic products: a proposal and example for sustainable health and healthcare by Emiliano Giovagnoni, Luisa Mattoli, Andrea Cossu, Vitalia Murgia

“…Frontiers in Drug Safety and Regulation…”
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Characterization of children’s prospective prescription review and exploration of factors influencing the success of interventions by Qiang Wen, Chuang Yang, Bangjian Deng, Yi Zhang, Lin Song

“…Therapeutic Advances in Drug Safety…”
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The crystal structure of methyl 4-(4-(methylsulfonyl)phenyl)-2-methyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate, C19H21NO5S by Li Yaoyao, Su Lai, Wang Tianqin, Zhang Le

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Quantitative Proteomic Analysis of Hepatic Tissue of T2DM Rhesus Macaque by Tingfu Du, Shuaiyao Lu, Qinfang Jiang, Yun Li, Kaili Ma

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The impact of solute carrier proteins on disrupting substance regulation in metabolic disorders: insights and clinical applications by Jiangxia Du, Minhui Shen, Jiajia Chen, Hao Yan, Zhifei Xu, Xiaochun Yang, Bo Yang, Bo Yang, Peihua Luo, Peihua Luo, Kefeng Ding, Yuhuai Hu, Qiaojun He, Qiaojun He, Qiaojun He, Qiaojun He

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Opportunities for implementing digital applications to monitor the impact of risk-minimization measures within the pharmacovigilance process: Scoping review of published literature by Ilko Getov, Denitsa Panayotova, Stanimir Dobrev, Maria Dimitrova, Valentina Petkova

“…The study provides an overview of innovative digital solutions to meet the evolving needs of drug safety monitoring and improve patient outcomes, focusing on implementing digital applications to enhance the monitoring of additional risk-minimization measures (aRMMs) for pharmacovigilance. …”
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Single-cell immunopathology of recurrent acute generalized exanthematous pustulosis associated with vancomycin by Eric M. Mukherjee, MD, PhD, Andrew Gibson, PhD, Matthew S. Krantz, MD, Rama Gangula, MS, Amy M. Palubinsky, PhD, Alan S. Boyd, MD, Jeffrey P. Zwerner, MD, PhD, Anna K. Dewan, MD, MS, Nontaya Nakkam, PhD, Katherine C. Konvinse, MD, PhD, Yueran Li, PhD, Ramesh Ram, PhD, Abha Chopra, PhD, Elizabeth J. Phillips, MD

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Markers of Inflammation and Fibrosis in Alcoholic Hepatitis and Viral Hepatitis C by Manuela G. Neuman, Hemda Schmilovitz-Weiss, Nir Hilzenrat, Marc Bourliere, Patrick Marcellin, Cristhian Trepo, Tony Mazulli, George Moussa, Ankit Patel, Asad A. Baig, Lawrence Cohen

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The Link between Hypersensitivity Syndrome Reaction Development and Human Herpes Virus-6 Reactivation by Joshua C. Pritchett, Radu M. Nanau, Manuela G. Neuman

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Gastrointestinal Inflammation and Repair: Role of Microbiome, Infection, and Nutrition by Helieh S. Oz, Sung-Ling Yeh, Manuela G. Neuman

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Women's perception of risks of adverse fetal pregnancy outcomes: a large-scale multinational survey by Irene Petersen, Hedvig Nordeng, Angela Lupattelli, Rachel L McCrea

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Characterization of Nutritional Composition, Antioxidative Capacity, and Sensory Attributes of Seomae Mugwort, a Native Korean Variety of Artemisia argyi H. Lév. & Vaniot by Jae Kyeom Kim, Eui-Cheol Shin, Ho-Jeong Lim, Soo Jung Choi, Cho Rong Kim, Soo Hwan Suh, Chang-Ju Kim, Gwi Gun Park, Cheung-Seog Park, Hye Kyung Kim, Jong Hun Choi, Sang-Wook Song, Dong-Hoon Shin

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HDAC1-3 inhibition triggers NEDD4-mediated CCR2 downregulation and attenuates immunosuppression in myeloid-derived suppressor cells by Zhiqi Xie, Jinjin Shao, Zeren Shen, Zhichao Ye, Yoshiaki Okada, Daisuke Okuzaki, Naoki Okada, Masashi Tachibana

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Updated treatment guidelines for drug-resistant TB: how safe are clofazimine-based regimens? by E. Pontali, M. Raviglione

“…Here, we discuss the cardiac safety of Cfz and the role of active drug safety monitoring at the programme level in collecting information on this issue.…”
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Digital twin-enhanced three-organ microphysiological system for studying drug pharmacokinetics in pregnant women by Katja Graf, José Martin Murrieta-Coxca, Tobias Vogt, Sophie Besser, Daria Geilen, Tim Kaden, Tim Kaden, Anne-Katrin Bothe, Diana Maria Morales-Prieto, Behnam Amiri, Behnam Amiri, Stephan Schaller, Ligaya Kaufmann, Martin Raasch, Ramy M. Ammar, Ramy M. Ammar, Christian Maass, Christian Maass

“…Long-term exposure simulations confirmed the value of this integrated system for predicting the non-toxic metabolization of prednisone.ConclusionThis approach may provide a potential non-animal alternative that could contribute to our understanding of drug behavior during pregnancy and may support early-stage drug safety assessment for vulnerable populations.…”
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Political economics in health and implications for neurosurgery diseases by Yi Han, Yutao Huang

“…It encompasses a diverse range of interconnected domains, including the economy, welfare, the environment, food and drug safety, pollution emissions, occupational safety, the quality of medical services, consumer rights, public health policy, healthcare policy, scientific research, and marketing management. …”
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Nano Delivery System for Atherosclerosis by Zhuoyi Rong, Xuan He, Tianjian Fan, Haitao Zhang

“…This review will focus on how nanoparticles effectively improve drug safety and efficacy, as well as the continuous development and optimization of nanoparticles of the same material and further explore current challenges and future opportunities in this field.…”
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