Current trends of Carbapenemase Production Amongst Multi-drug Resistant Gram-Negative Bacteria in a Tertiary-Care Hospital in West Bengal by Arunima Chakravarty, Raja Ray, Ananda S. Mondal, Hirak J. Raj

“…Objectives: Our aim was to study the prevalence of Carbapenemase producing multi-drug-resistant gram-negative bacteria in different zones of our hospital to aid in antimicrobial resistance surveillance. …”
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Decoding MexB efflux pump genes: structural, molecular, and phylogenetic analysis of multidrug-resistant and extensively drug-resistant Pseudomonas aeruginosa by Muhammad Bilal Habib, Naseer Ali Shah, Afreenish Amir, Huda Ahmed Alghamdi, Muhammad Haseeb Tariq, Kiran Nisa, Mariam Ammoun

“…ObjectiveEmerging drug resistance in Pseudomonas aeruginosa is of great concern in clinical settings. …”
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A MALDI-TOF MS-based multiple detection panel of drug resistance-associated multiple single-nucleotide polymorphisms in Candida tropicalis by Feifei Wan, Min Zhang, Jian Guo, Huiping Lin, Xiaoguang Zhou, Lixin Wang, Wenjuan Wu

“…We developed and validated a rapid, high-throughput, and cost-effective panel to detect and monitor drug-resistance mutations of C. tropicalis.…”
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Detection of 5 Kinds of Genes Related to Plasmid-Mediated Quinolone Resistance in Four Species of Nonfermenting Bacteria with 2 Drug Resistant Phenotypes by De-Song Ming, Qing-Qing Chen, Xiao-Ting Chen

“…But, the strains of two drug resistant phenotypes were not significantly different in the carrying rate of intI1. …”
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Second-generation BRAF inhibitor Encorafenib resistance is regulated by NCOA4-mediated iron trafficking in the drug-resistant malignant melanoma cells by Ceyda Colakoglu Bergel, Isil Ezgi Eryilmaz, Gulsah Cecener, Unal Egeli

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Plasmodium falciparum transcription factor AP2-06B is mutated at high frequency in Southeast Asia but does not associate with drug resistance by Qiyang Shi, Changhong Wang, Wenluan Yang, Xiaoqin Ma, Jianxia Tang, Jiayao Zhang, Guoding Zhu, Yinlong Wang, Yaobao Liu, Xiaoqin He

Subjects: “…drug-resistant…”
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Prospective surveillance study to detect antimalarial drug resistance, gene deletions of diagnostic relevance and genetic diversity of Plasmodium falciparum in Mozambique: protocol by Alexandra Wharton-Smith, Caterina Guinovart, Pedro Aide, Francisco Saute, Alfredo Mayor, Bryan Greenhouse, Baltazar Candrinho, Joshua L Proctor, Arantxa Roca-Feltrer, Clemente da Silva, Eduard Rovira-Vallbona, Craig Bonnington, Caitlin Bever, Arlindo Chidimatembue, Maria Rodrigues, Neide Canana, Paulo Arnaldo, Simone Boene, Sonia Enosse

“…This study aims to operationalise a functional malaria molecular surveillance system in Mozambique for guiding malaria control and elimination.Methods and analyses This prospective surveillance study seeks to generate Plasmodium falciparum genetic data to (1) monitor molecular markers of drug resistance and deletions in rapid diagnostic test targets; (2) characterise transmission sources in low transmission settings and (3) quantify transmission levels and the effectiveness of antimalarial interventions. …”
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Using β-Elemene to reduce stemness and drug resistance in osteosarcoma: A focus on the AKT/FOXO1 signaling pathway and immune modulation by Shaochun Zhang, Zhijie Xing, Jing Ke

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Nucleotide metabolism-associated drug resistance gene NDUFA4L2 promotes colon cancer progression and 5-FU resistance by Hongxin HE, Shiyao ZHENG, Shangkun JIN, Weijie HUANG, Enhao WEI, Shen GUAN, Chunkang YANG

“…We calculated the half-maximal inhibitory concentrations (IC50) of 5-Fluorouracil (5-FU) in colorectal cancer patients using the “oncopredict” package, screened nucleotide metabolism-related drug resistance genes, and constructed a risk score model. …”
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The implementation of whole-genome sequencing for Mycobacterium tuberculosis in Vietnam by D.T. Huong, T.M. Walker, D.T. Ha, K.T.T. Ngoc, V.N. Trung, L.T. Nam, P.T.T. Ngoc, L.T. Nguyet, N.T. Thanh, N.H. Minh, N.K. Cuong, N.V. Khiem, H.V.T. Ngoc, T.T.T. Bich, H.N. Hong, P.P. Trieu, L.K. Lan, K. Lan, N.N. Hue, N.T.L. Huong, T.L.T.N. Thao, N.L. Quang, T.D.D. Anh, D.W. Crook, G.E. Thwaites, N.T.T. Thuong, N.B. Hoa, D.V. Luong, N.V. Hung

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Dynamic Challenges of Active Tuberculosis: Prevalence and Risk Factors of Co-Infection in Clinical and Microbiological Characteristics at King Abdulaziz University Hospital, Jeddah... by Mokhtar JA, Attallah DM, Jiman-Fatani AA, Al-Rabia MW, Alqarni MA, Saleh BH, Amboon MM, Altorki TA, Alkuwaity KK, Abujamel T, Kaki R, Albarakati TN, Daghistani H, Ismail MA, Alharbi O, Abu ITM, Alfadil A, Ibrahem K, Mufrrih M, Sait AM

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Brief communication: virological outcomes and dolutegravir resistance mutations in HIV-infected patients: a multicenter retrospective cohort study in Mozambique by Anna Maria Doro Altan, Noorjehan Majid, Stefano Orlando, Elton Uamusse, Marcia Rafael, Zita Sidumo, Giovanni Guidotti, Fausto Ciccacci

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Modelling HIV superinfection among men who have sex with men by Xiaodan Sun, Yanni Xiao, Zhihang Peng

Subjects: “…drug resistance…”
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Antibiotic cycling versus mixing: The difficulty of using mathematicalmodels to definitively quantify their relative merits by Robert E. Beardmore, Rafael Peña-Miller

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Rotating antibiotics selects optimally against antibiotic resistance, in theory by Robert E. Beardmore, Rafael Peña-Miller

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Efficacy of Xpert MTB/RIF assay in detecting Mycobacterium tuberculosis in samples with different results by smear and culture in a coastal city with high incidence of tuberculosis by Gang Feng, Hongyu Jiang, Ying Chen

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An Update on African Trypanocide Pharmaceutics and Resistance. by Keneth Iceland, Kasozi, MacLeod, Ewan Thomas, Ntulume, Ibrahim, Welburn, Susan Christina

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Antibacterial activity of selenium nanoparticles/copper oxide (SeNPs/CuO) nanocomposite against some multi-drug resistant clinical pathogens by Ahmed Morad Asaad, Sara A. Saied, Mohammad M. Torayah, N. I. Abu-Elsaad, Samah Mohammed Awad.

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A Direct and Sensitive Method for Determination of 5-Fluorouracil in Colorectal Cancer Cells: Evaluating the Effect of Stromal Cell on Drug Resistance of Cancer Cells by Fengjing Xu, Zhipeng Wang, Xinhua Song, Mengwei Zhang, Lili Cui, Yanping Liu, Hongxia Yan, Shouhong Gao, Yan Liu, Wansheng Chen

“…The preliminary results present that NIH3T3 could enhance the drug resistance of MC38 to 5-FU with a decreased intracellular concentration of 5-FU in MC38, which showed a positive relationship with NIH3T3 number.…”
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Evaluation of the Drug-Resistant Tuberculosis (DR-TB) management component under the National Tuberculosis Elimination Program (NTEP) in Kerala, India, 2021-22 by Raman Swathy Vaman, Madhanraj Kalyanasundaram, Malu Mohan, Narayana Pradeepa, Manoj V. Murhekar

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