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1001
Characterization and antibacterial activity of biogenic iron nanoparticles using Proteus mirabilis
Published 2024-01-01“…These NPs, including their antimicrobial qualities, how they work, how they affect drug-resistant microbes, the risks involved with using them, the unique qualities of NPs, their mode of action as antibacterial properties, and the elements that influence how well they function in a therapeutic setting all are thoroughly investigated. …”
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1002
Antibiotics Profile, Prevalence of Extended-Spectrum Beta-Lactamase (ESBL), and Multidrug-Resistant Enterobacteriaceae from Different Clinical Samples in Khartoum State, Sudan
Published 2020-01-01“…Therefore, this study aimed to deliver the indication of different resistant profiles of clinically isolated Enterobacteriaceae from different sources of samples from Khartoum state, Sudan, and to determine the prevalence rate of extended-spectrum beta-lactamase (ESBL), multidrug-resistant (MDR), extensively drug-resistant (XDR), and pandrug-resistant (PDR) bacteria. …”
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1003
Prevalence and factors associated with multidrug resistant Escherichia coli carriage on chicken farms in west Nile region in Uganda: A cross-sectional survey.
Published 2025-01-01“…Infections with multi-drug-resistant (MDR) pathogens in food-animals threaten public health and food security. …”
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1004
SEEG-Based Bilateral Seizure Network Analysis for Neurostimulation Treatment
Published 2025-01-01“…Epilepsy patients with drug-resistant seizures emanating from two or more distinct regions of left and right hemispheres are the primary candidates for neurostimulation treatment. …”
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1005
Microbial Load and Antibiotic Resistance of Escherichia coli and Staphylococcus aureus Isolated from Ready-to-Eat (RTE) Khebab Sold on a University Campus and Its Environs in Ghana
Published 2021-01-01“…Also, the S. aureus and E. coli isolated were multiresistant to the antibiotics tested and could be a medium for the transmission of antibiotic-resistant bacteria and therefore expose consumers to a high risk of contracting foodborne infections with drug-resistant strains.…”
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1006
The challenges associated with a ketogenic diet: a narrative review
Published 2025-01-01“…For ‘intractable’ epilepsy (when seizures cannot be managed completely by drug therapy, also referred to as ‘refractory’, ‘uncontrolled’ or ‘drug-resistant’ epilepsy) the dietary fat to carbohydrate plus protein ratio is held at a ratio of 4:1 or 3:1. …”
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1007
Antibacterial Efficacy and Healing Potential of Honey from Different Zones in Nigeria on Diabetic-Induced Wound Infection in Wistar Rats
Published 2022-01-01“…There is an increase in drug-resistant strains causing infection, thus making available therapeutics less effective. …”
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1008
Natural Cyclic Peptides: Synthetic Strategies and Biomedical Applications
Published 2025-01-01“…Their unique ability to combine high specificity with desirable pharmacokinetic properties makes them valuable tools in addressing unmet medical needs, such as combating drug-resistant pathogens and targeting challenging biological pathways. …”
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1009
Carbapenem-Resistant Gram-Negative Bacterial Infections at a Tertiary Health Care Center in Nepal: An Observational Study
Published 2024-12-01“… Introduction: Carbapenems are last-resort antibiotics and are considered the drugs of choice for infections caused by multi-drug-resistant bacteria. During the last several years, there has been an alarming global increase in the detection and spread of Carbapenem-resistant organisms among gram-negative bacteria. …”
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1010
Genomic characterization of antimicrobial-resistance and virulence factors in Salmonella isolates obtained from pig farms in Antioquia, Colombia.
Published 2025-01-01“…<h4>Conclusion</h4>The presence of multi-drug resistant Salmonella strains in pigs destined for human consumption in Antioquia, Colombia was determined. …”
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1011
Tackling Microbial Resistance and Emerging Pathogens with Next-Generation Antibiotics
Published 2024-08-01“…However, the misuse and abuse of antimicrobial agents are accompanied by major ramifications like antimicrobial resistance, creating drug-resistant superbugs. This issue is concerning worldwide, as dwindling effective antibiotics lead to rising healthcare costs, re-hospitalization, and disease severity. …”
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1012
Rifampicin and isoniazid resistance not promote fluoroquinolone resistance in Mycobacterium smegmatis.
Published 2025-01-01“…<h4>Background</h4>The emergence of drug-resistant Tuberculosis (TB) has made treatment challenging. …”
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1013
Improved Clinical Outcomes with Appropriate Meropenem De-escalation in Patients with Febrile Neutropenia
Published 2024-12-01“…Introduction: Antibiotic stewardship is a critical aspect of managing cancer patients with febrile neutropenia (FN) to limit the development of drug-resistant organisms and minimize adverse drug effects. …”
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1014
A Comprehensive Study of the Relationship between the Production of β-Lactamase Enzymes and Iron/Siderophore Uptake Regulatory Genes in Clinical Isolates of Acinetobacter baumannii...
Published 2021-01-01“…Based on our knowledge from this study, the association between β-lactamase production and IUS genes in A. baumannii plays an essential role in the emergence of drug-resistant strains.…”
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1015
Characterization of Carbapenem-Resistant Acinetobacter baumannii Strains Isolated from Hospitalized Patients in Palestine
Published 2017-01-01“…The detection of these drug resistant pathogens is a reminder of the importance of active surveillance for resistant bacteria in order to prevent their spread in hospital settings.…”
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1016
The effect of carbonyl cyanide m-chlorophenyl-hydrazine on antibiotic susceptibility in MDR Enterobacteriaceae isolates in Babylon, Iraq
Published 2024-01-01“…Abstract Background: One of the efflux pump inhibitors is carbonyl cyanide 3-chlorophenylhydrazone (CCCP) that has often been found to increase the susceptibility of a number of multi-drug resistant (MDR) MDR bacteria, isolated from human clinical specimens. …”
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1017
Exploring the Genetic Landscape of Mycobacterium tuberculosis: Unlocking the Differences in Between Latent and Active Tuberculosis
Published 2024-12-01“…Results: Three distinct frameshift mutations were identified in the fbiC, PPE35, and ald genes, and one upstream mutation in whiB6 genes in all studied isolates under dormancy, irrespective of their susceptibility patterns (P < 0.01). Among drug-resistant strains, at the exponential phase isolated from patients with prolonged treatment, 5%–7% had PPE35, ald mutations, whereas 95% had the whiB6 mutation, suggesting that adaptive stress responses may be triggered under in vivo conditions. …”
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1018
Understanding Nigeria’s antibiotic resistance crisis among neonates and its future implications
Published 2025-01-01“…Studies show a significant rise in multi-drug-resistant infections, with almost half of Escherichia coli and 86% of Staphylococcus aureus strains among newborns resistant to conventionally used antibiotics like penicillin. …”
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1019
Infected burn wound healing using Hydroxy-propyl-methyl cellulose gel containing bacteriophages against Pseudomonas aeruginosa and Klebsiella pneumoniae
Published 2025-02-01“…Conclusion: The results of this study indicate that lytic phages are powerful biological tools for the treatment of bacterial infections in burn wounds, which can be considered as one of the alternatives for drug-resistant bacterial species and the high costs of antibiotics; though further animal and trial studies are needed. …”
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1020
The Impact of Zinc Supplementation on the Course of Infections
Published 2025-02-01“…Zinc also destabilized microbial membranes, inhibiting bacterial and viral replication, including multi-drug-resistant strains. Furthermore, zinc supplementation improved gut microbiome composition, promoting beneficial bacteria and reducing pathogenic growth. …”
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