Evaluating the Awareness and Knowledge about Probiotics in Postgraduate Students of an Indian Dental College by Kumari Upasana, Rameet Sandhu, Prerna Kataria, Abhik Sinha, Ritesh Vatsa, Nisha Parveen

“…Background: Probiotics are vital in maintaining gut health. With increasing drug resistance, it is crucial to keep healthy gut microbes, making probiotics essential. …”
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Whole genome sequencing and analysis of a goose-derived Mycoplasma gallisepticum in Guangdong Province, China by Zhou Yuanyuan, Song Shuti, Li Weihuo, Jia Yixin, Li Yangshuo, Liang Jingyi, Yao Zhaofeng, Zhang Nan

“…This study investigated the pathogenicity and drug resistance of an MG strain isolated from geese and whole-genome sequenced the strain.…”
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Targeting secretory autophagy in solid cancers: mechanisms, immune regulation and clinical insights by Xinyu Li, Haiying Zhao

“…Moreover, substances released by secretory autophagy convey biological signals to the TME, inducing immune dysregulation and contributing to drug resistance. Therefore, elucidating the mechanisms underlying secretory autophagy is essential for improving clinical treatments. …”
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Effect of neutrophils on tumor immunity and immunotherapy resistance with underlying mechanisms by Jiali Yao, Linlin Ji, Guang Wang, Jin Ding

“…Secondly, we review the mechanisms by which neutrophils affect drug resistance in tumor immunotherapy from the aspects of the immune microenvironment, tumor antigens, and epigenetics. …”
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'Pseudo' Treatment Failure of Pulmonary Tuberculosis in Association with a Tuberculoma by Richard Long, Sylvia Chomyc, Evelina Der, Daniel S Sitar

“…Failure of tuberculosis patients to respond to treatment is usually explained by one or more of five mechanisms: improper drug prescription; patient nonadherence to prescribed therapy; primary or acquired drug resistance; drug malabsorption; and rarely, exogenous reinfection with a drug-resistant isolate. …”
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Exploring Drug Targets in Isoprenoid Biosynthetic Pathway for Plasmodium falciparum by Tabish Qidwai, Farrukh Jamal, Mohd Y. Khan, Bechan Sharma

“…Emergence of rapid drug resistance to existing antimalarial drugs in Plasmodium falciparum has created the need for prediction of novel targets as well as leads derived from original molecules with improved activity against a validated drug target. …”
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Mathematical Model for Transmission and Control of Malaria Disease in Ihandiro Sub-County Kasese District. by Birumbu, Brian

“…A mathematical model was developed to examine the dynamics of malaria in Uganda, factoring in drug resistance, treatment methods, and the use of mosquito nets as preventive measures. …”
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Whole genomic analysis uncovers high genetic diversity of rifampicin-resistant Mycobacterium tuberculosis strains in Botswana by Tuelo Mogashoa, Tuelo Mogashoa, Johannes Loubser, Ontlametse T. Choga, Ontlametse T. Choga, Justice Tresor Ngom, Wonderful T. Choga, Wonderful T. Choga, Mpaphi B. Mbulawa, Tuduetso Molefi, One Stephen, Topo Makhondo, Kedumetse Seru, Patience Motshosi, Boitumelo Zuze, Joseph Makhema, Rosemary M. Musonda, Dimpho Otukile, Chawangwa Modongo, Botshelo T. Kgwaadira, Keabetswe Fane, Simani Gaseitsiwe, Rob M. Warren, Sikhulile Moyo, Sikhulile Moyo, Sikhulile Moyo, Sikhulile Moyo, Anzaan Dippenaar, Elizabeth M. Streicher

“…BackgroundThe emergence of drug-resistant Mycobacterium tuberculosis (M. tb) strains remains a threat to tuberculosis (TB) prevention and care. …”
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Resensitizing β‐Lactams by Reprogramming Purine Metabolism in Small Colony Variant for Osteomyelitis Treatment by Tingwang Shi, Qiong Wu, Zesong Ruan, Zhiyuan Luo, Wenbo Wang, Zhao Guo, Yihong Ma, Xin Wang, Guangyu Chu, Han Lin, Min Ge, Yunfeng Chen

“…In this study, phenotypically stable SCV strains are successfully recovered from clinical specimens, characterized by elevated drug resistance and reduced immunogenicity. Multi‐omics analysis revealed that the acquired high drug resistance is associated with altered flux in the purine metabolism pathway, attributable to mutations in the hypoxanthine phosphoribosyltransferase (hpt) gene. …”
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Can Ethiopia eliminate malaria? Malaria burden: insights from the pre-elimination era, current challenges and perspectives by Dagmawi Woldesenbet, Yalewayker Tegegne, Abdulhakim Mussema, Elias Tamene, Kemal Mohamed, Wagaw Abebe, Melese Mekuria, Kasahun Bogale, Habtamu Geremew, Mufta Muzemil Shifa, Mulugeta Aemero Tegegne

“…Factors contributing to this resurgence include emerging drug resistance, insecticide resistance, and genetic mutations such as single nucleotide polymorphisms. …”
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Cooperative Optimization QoS Cloud Routing Protocol Based on Bacterial Opportunistic Foraging and Chemotaxis Perception for Mobile Internet by Shujuan Wang, Long He, Guiru Cheng

“…This mechanism is based on the characteristics of drug resistance of bacteria and the structure of the field, and through many iterations of the individual behavior and population behavior the bacteria can be spread to the food gathering area with a certain probability. …”
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Circulating Tumor Cells Measurements in Hepatocellular Carcinoma by Franck Chiappini

“…CTC are an interesting source of biological information in order to understand dissemination, drug resistance, and treatment-induced cell death. Our aim is to review and analyze the different new methods existing to detect, enumerate, and characterize the CTC in the peripheral circulation of patients with HCC.…”
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Orofacial antibioma and its management by Priyadharsini Nataraj, Ashwini Ravi, Dineshkumar Thayalan, Rameshkumar Annasamy, Rajkumar Krishnan

“…Since there is no established protocol for the use of antibiotics in dentistry, they have frequently been used improperly or excessively. Drug resistance and other problems are brought on by this. …”
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Galangin-Loaded Gold Nanoparticles: Molecular Mechanisms of Antiangiogenesis Properties in Breast Cancer by Malik H. Qaddoori, Hanady S. Al-Shmgani

“…Angiogenesis is important for tissue during normal physiological processes as well as in a number of diseases, including cancer. Drug resistance is one of the largest difficulties to antiangiogenesis therapy. …”
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Current developments in personalized treatment strategies for elderly acute myelogenous leukemia patients by Xueting Hou, Jizhang Bao

“…Acute myelogenous leukemia(AML) is a life-threatening hematologic malignancy that predominantly affects the elderly.Currently, chemotherapy and hematopoietic stem cell transplantation are the primary treatment modalities for AML, though their clinical application is limited in older patients.Recent years have seen the development of novel molecular targeted therapies, such as isocitrate dehydrogenase 1/2 (IDH1/2) and Feline macrophage stimulator-like tyrosine kinase 3 (FLT3) inhibitors, as well as individualized approaches like chimeric antigen receptor T-cell (CAR-T) therapy.However, due to patient heterogeneity and drug resistance, treatment outcomes for elderly AML remain unsatisfactory, underscoring the need for more precise and safer individualized treatment strategies.The combination of chemotherapy with novel targeted or immunotherapies shows promise as a future treatment direction.This research reviews the latest advances in the treatment of elderly AML, with a focus on achieving more individualized and safer therapeutic approaches.…”
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The Anticancer Perspective of Tangeretin: A Small Review by Yuan Xu, Xi Yan, Junpeng Zhuang, Haijun Hao

“…Tangeretin can also work with other chemotherapy drugs, such as cisplatin, to reduce the drug resistance of cancer cells and improve the therapeutic effect of chemotherapy drugs. …”
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An Optimized Protocol for Simultaneous Propagation of Patient-derived Organoids and Matching CAFs by Jenny Högström, Taru Muranen

“…Our matching PDOs and CAFs will provide researchers with a new resource to study the influence of the tumor microenvironment on various aspects of cancer biology such as cell growth and drug resistance in HR+ breast cancer.…”
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2-Amino-1,3,4-thiadiazoles as prospective agents in trypanosomiasis and other parasitoses by Serban Georgeta

“…Due to old medications and drug resistance worldwide, there is an urgent need for new antiparasitic drugs. 1,3,4-Thiadiazoles have been widely studied for medical applications. …”
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HPRNA: Predicting synergistic drug combinations for angina pectoris based on human pathway relationship network algorithm. by Mengyao Zhou, Mengfan Xu, Xiangling Zhang, Xiaochun Xing, Yang Li, Guanghui Wang, Guiying Yan

“…Over the years, synergistic drug combinations therapies have attracted widespread attention due to its advantages of overcoming drug resistance, increasing treatment efficacy and decreasing toxicity. …”
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An Anaplastic Lymphoma Kinase-positive Inflammatory Myofibroblastic Tumor with Rapidly Acquired Resistance to First-line Anaplastic Lymphoma Kinase Inhibitor: A Case and Literature... by Shu-Cheng Wu, Hsing-Wu Chen

“…(Gly1202Arg), which is a common mechanism of drug resistance in ALK fusion-positive non-small cell lung cancer. …”
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