Crystal structure of (E)-7-methoxy-2-((6-methoxypyridin-3-yl)methylene)-3,4-dihydronaphthalen-1(2H)-one, C18H17NO3 by Wang Lei, Meng Qing-Guo, Jiang Nan, Wei Lin, Wang Chun-Hua

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Crystal structure and anti-inflammatory activity of (E)-7-fluoro-2-((5-methoxypyridin-3-yl)methylene)-3,4-dihydronaphthalen-1(2H)-one, C17H14FNO2 by Sun Jia-Jia, Zhang Xiao-Fan, Meng Qing-Guo, Li Hong-Juan, Wang Chun-Hua

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Studies on the Loading and Release of Metformin HCl Using Hydrogels with EGDMA and MBA as Crosslinkers by Ariyaldi Ariyaldi, Noverra Mardhatillah Nizardo, Maria Lucia Ardhani Dwi Lestari

“…The P(NVCL-co-DMAEMA) hydrogel has the potential for a drug delivery system. However, additional optimizations are necessary to improve the efficiency of the hydrogels as a carrier.…”
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Calcium Phosphate Nanoparticles Functionalized with a Cardio-Specific Peptide by Federica Mancini, Lorenzo Degli Esposti, Alessio Adamiano, Jessica Modica, Daniele Catalucci, Dora Mehn, Otmar Geiss, Michele Iafisco

“…To overcome this challenge, an effective drug delivery system is essential to protect and efficiently transport peptides to their intended targets. …”
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Local Exosome Inhibition Potentiates Mild Photothermal Immunotherapy Against Breast Cancer by Qian Chen, Yanan Li, Jiameng Hu, Zhenyu Xu, Shengyi Wang, Naicong Cai, Mengjiao He, Yifang Xiao, Yuan Ding, Mengjuan Sun, Chunjiayu Li, Yiyang Cao, Zhongyuan Wang, Fang Zhou, Guangji Wang, Chen Wang, Jiasheng Tu, Haiyang Hu, Chunmeng Sun

“…Thus, a multi‐stage drug delivery system is designed that concurrently delivers photosensitizers (reduced graphene oxide nanosheets, NRGO), anti‐PD‐L1 antibodies, and exosome inhibitors (sulfisoxazole). …”
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Synthesis, Structural Characterization, and Preclinical Efficacy of a Novel Paclitaxel-Loaded Alginate Nanoparticle for Breast Cancer Treatment by Ahmed A. Markeb, Nagwa A. El-Maali, Douaa M. Sayed, Amany Osama, Mohamed A. Y. Abdel-Malek, Amen H. Zaki, Mostafa E. A. Elwanis, James J. Driscoll

“…PTX was combined with ALG in a nanoparticle as a drug delivery system designed to improve breast cancer tumor cell killing. …”
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A cryo-shocked M2 macrophages based treatment strategy promoting repair of spinal cord injury via immunomodulation and axonal regeneration effects by Ermei Lu, Kecheng Zhou, Jiansen Miao, Yanlin Zhu, Jiyao Tang, Siting Du, Yanzhen Feng, Linyuan Jiang, Tianyao Jiang, Ting Huang, Ping Li, Xinjun Miao, Qi Han, Jian Xiao

“…To tackle these issues, we developed an innovative biomimetic drug delivery system using liquid nitrogen-treated M2 macrophages (LNT M2) which internalized paclitaxel (PTX) nanoparticles beforehand. …”
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In situ delivery of synthetic preimplantation factor using aldehyde-modified hyaluronic acid hydrogel with immobilized complexes of chondroitin sulfate derivatives by Tutut Habibah, Andrea Exnerová, Kristina Nešporová, Una FitzGerald, Abhay Pandit, Marek Ingr, Martin Pravda, Vladimír Velebný

“…This study presents an injectable drug delivery system (DDS) using 2 % (w/v) aldehyde-modified hyaluronic acid (HAOX) and chondroitin sulfate (CSOX) to deliver 100 µg of Fluorescein isothiocyanate-modified SPIF (FITC-SPIF). …”
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Dual functional hydrogel of osteoclastic-inhibition and osteogenic-stimulation for osteoporotic bone defect regeneration by Lei Yu, Wentao Wang, Chang Lv, Qian Chen, Peng Yang, Zhenrong Qi, Haomiao Yu, Ruiqi Cao, Wenhao Li, Yi Qin, Gaoran Ge, Peilai Liu, Lixin Zhu, Houyi Sun, Dechun Geng, Liang Zhang

“…In this study, we designed a drug delivery system composed of mesoporous bioactive glass (MBG) and photo-crosslinked hyaluronic acid methacrylate (HAMA). …”
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Bioactive sorbicillinoid derivatives from an endophytic fungus Trichoderma citrinoviride by Yan-Ping Xia, Yan Xie, Li Rao, Guo-Ping Yin

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Lipid Horizons: Recent Advances and Future Prospects in LBDDS for Oral Administration of Antihypertensive Agents by null Preeti, Sharda Sambhakar, Rohit Malik, Saurabh Bhatia, Ahmed Al Harrasi, Renu Saharan, Geeta Aggarwal, Suresh Kumar, Renu Sehrawat, Chanchal Rani

“…The lipid-based drug delivery system (LBDDS) is a well-established technique that is anticipated to bring about comprehensive transformations in the pharmaceutical field, impacting the management and administration of drugs, as well as treatment and diagnosis. …”
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Crystal structure of (E)-2-((3-fluoropyridin-4-yl)methylene)-7-methoxy-3,4-dihydronaphthalen-1(2H)-one, C17H14FNO2 by Wang Chen, Wang Lei, Meng Qing-Guo, Huang Zhi-Xin, Ma Nuan-Nuan, Wang Chun-Hua

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Development of a conjunctival contact–type drug delivery device for latanoprost using hyaluronic acid by Soomin Lee, Mi-Young Jung, Choul Yong Park

“…This study evaluates the efficacy and safety of using freeze-dried hyaluronic acid (HA) as a carrier for a novel conjunctival-contact drug delivery system. We developed HA tablets loaded with latanoprost (HA-latanoprost) and verified the concentration using high-performance liquid chromatography. …”
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Environmental friendly carrier material for nifedipine as hypertension drug by E. Budianto, S.H. Astuti

“…One way of developing a controlled drug delivery system is making nifedipine microcapsules by using environmentally friendly polymers of polylactic acid and polycaprolactone via the evaporation method using oil-in-water solvents. …”
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Trust Region Policy Learning for Adaptive Drug Infusion with Communication Networks in Hypertensive Patients by Mai The Vu, Seong Han Kim, Ha Le Nhu Ngoc Thanh, Majid Roohi, Tuan Hai Nguyen

“…To overcome these challenges, this paper presents an adaptive closed-loop drug delivery system to control AABP by adjusting the infusion rate, as well as a communication time delay (CTD) for analyzing the wireless connectivity and interruption in transferring feedback data as a new insight. …”
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Supramolecular discrimination and diagnosis-guided treatment of intracellular bacteria by Jia-Hong Tian, Siyuan Huang, Ze-Han Wang, Juan-Juan Li, Xianhui Song, Ze-Tao Jiang, Bing-Sen Shi, Ying-Ying Zhao, Hui-Yan Zhang, Ke-Rang Wang, Xin-Yue Hu, Xinge Zhang, Dong-Sheng Guo

“…This diagnostic approach executes the significant guiding missions of screening a customized host-guest drug delivery system by disclosing the rationale behind the discrimination. …”
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Enhanced precise therapy of ROS-sensitive dual-layer shell nanoparticles loading quercetin on DSS-induced ulcerative colitis mice by Yang Bai, Danling Jiang, Boda Wu, Jiao Peng, Ji Wang, Yuhui Chen, Xi Li

“…Therefore, Que@Gel-DA NPs, a ROS-sensitive nano-drug delivery system, represent a novel therapeutic approach for the clinical intervention of UC.…”
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Liposome-like encapsulation of fish oil-based self-nano emulsifying formulation for improved bioavailability by Iqbal Ahmad, Aparana Dogra, Tanya Nagpal, Chandvi Sharma, Sudhakar Singh, Nikhil Shaiva, Gaurav Saini, Kanishk Luhach

“…This study aimed to develop a novel liposome-like self-micro emulsifying drug delivery system (SMEDS) to enhance the bioavailability of fish oil-based EPA and DHA. …”
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Polyhydroxyalkanoates Biopolymer Production by Moderately Halophilic Paracoccus onubensis Strain E3: Extraction, Characterization and Synergistic Activity with Sorafenib Drug again... by Hend A. Hamedo, Ahmed E.M. Shokr, Omnia T. Abd-Elsalam, Naglaa Elshafey

“…Our findings indicate that Paracoccus onubensis strain E3 is a promising candidate for producing PHAs, which could be used as a drug delivery system for HCC treatment with sorafenib drug. …”
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CD7‐targeting pro‐apoptotic extracellular vesicles: A novel approach for T‐cell haematological malignancy therapy by Bei Zhang, Jianqiang Chen, Jiming Chen, Yingying Shen, Yinghu Chen, Shibo Wang, Chengyan Zhang, Yuzhou He, Huajun Feng, Jiaoli Wang, Zhijian Cai

“…Here, we developed a drug delivery system utilizing 293T cell‐derived extracellular vesicles (EVs) modified with an anti‐CD7 single‐chain variable fragment (αCD7/EVs). …”
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