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How Are n-3 LCPUFAs Antiarrhythmic? A Reassessment of n-3 LCPUFAs in Cardiac Disease
Published 2012-01-01“…Long-chain n-3-polyunsaturated fatty acids (n-3 LCPUFAs), referring particularly to marine-derived eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), have been shown to be effective in treating arrhythmias in some clinical trials and animal studies. …”
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Investigation of physicochemical, microbiological and sensorial properties for organic and conventional retail chicken meat
Published 2021-03-01“…Alpha-linoleic acid, docosahexaenoic acid was found to be higher in organic chicken meat. …”
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The Janus Face of Lipids in Human Breast Cancer: How Polyunsaturated Fatty Acids Affect Tumor Cell Hallmarks
Published 2012-01-01“…While most of the results obtained with docosahexaenoic acid and/or eicosapentaenoic acid show a decrease of tumor cell proliferation and/or aggressivity, there is some evidence that other lipids, which accumulate in breast cancer tissues, such as arachidonic acid may have opposite effects. …”
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Profiling the response of individual gut microbes to free fatty acids (FFAs) found in human milk
Published 2025-02-01“…Higher concentrations (0.1 %, 1 %) of docosahexaenoic acid significantly inhibited the growth of five of eight pathobionts. …”
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Maternal Vitamin B12 in Pregnancy and Placental Development
Published 2024-01-01“…Our review identified evidence of B12 deficiency resulting in impaired placental development, greater placental inflammation, and modulation of placental docosahexaenoic acid concentration, collectively suggestive of vitamin B12 deficiency as a determinant of both maternal and fetal health outcomes. …”
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A Revision on the Effectiveness of Omega-3 Polyunsaturated Fatty Acids as Monotherapy in the Treatment of Major Depressive Disorder
Published 2022-01-01“…Two well-trained reviewers independently looked at the most significant randomized clinical trials (RCTs) from the PubMed database regarding PUFAs’ employment in MDD compared to placebo; “major depressive disorder” and “omega-3 fatty acids,” or “omega-6 fatty acids,” or “polyunsaturated fatty acids (PUFA),” or “n − 3 polyunsaturated fatty acids,” or “eicosapentaenoic acid (EPA),” or “docosahexaenoic acid (DHA)” were used as the medical subject keywords. …”
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Biochemical Factors Modulating Cellular Neurotoxicity of Methylmercury
Published 2011-01-01“…., N-acetyl cysteine, (NAC); diethyl maleate, (DEM); docosahexaenoic acid, (DHA); selenomethionine, SeM; Trolox) and MeHg treatment on intercellular antioxidant status, MeHg content, and other endpoints was evaluated. …”
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Systematic Review of Randomized Clinical Trials on Safety and Efficacy of Pharmacological and Nonpharmacological Treatments for Retinitis Pigmentosa
Published 2015-01-01“…The 19 RCTs included in this systematic review included trials on hyperbaric oxygen delivery, topical brimonidine tartrate, vitamins, docosahexaenoic acid, gangliosides, lutein, oral nilvadipine, ciliary neurotrophic factor, and valproic acid. …”
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Polyunsaturated Fatty Acid Dietary Supplementation Induces Lipid Peroxidation in Normal Dogs
Published 2010-01-01“…Dogs (n=54) consumed a diet supplemented with 0.5% conjugated linoleic acid/dry matter, 1.0% conjugated linoleic acid/dry matter, or 200 mg/kg docosahexaenoic acid/eicosapentaenoic acid for 21 days. All dogs exhibited significantly increased plasma PUFA concentrations. …”
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Resolution of Inflammation in Neurodegenerative Diseases: The Role of Resolvins
Published 2020-01-01“…Among PUFA-derived proresolving mediators, different eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) derivatives have been described, namely, resolvins (resolution phase interaction products), which exert their anti-inflammatory and immune-regulatory activities through specific G-protein-coupled receptors. …”
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Molecular Circuits of Resolution in the Eye
Published 2010-01-01“…In addition to AA, the ω-3 polyunsaturated fatty acids (PUFAs) eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) also serve as substrates to generate potent and protective autacoids, such as resolvins and neuroprotectin (i.e., NPD1), respectively. …”
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Relationship between Fecal Content of Fatty Acids and Cyclooxygenase mRNA Expression and Fatty Acid Composition in Duodenal Biopsies, Serum Lipoproteins, and Dietary Fat in Colecto...
Published 2010-01-01“…In the ileostomy group separately (n=12), the fecal content of arachidonic acid was correlated negatively to the proportions of eicosapentaenoic acid and docosahexaenoic acid in duodenal biopsies. Total serum-cholesterol was negatively correlated to the fecal content of saturates and monounsaturates. …”
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Effects of the Maximum Recommended Levels of Fumonisins in the EU on Oxylipin Profiles in the Liver and Brain of Chickens
Published 2024-12-01“…In the brain, at four days, the most discriminative OLs were derived from ω3-PUFAs, including docosahexaenoic acid, docosapentaenoic acid, and alpha-linolenic acid, via the LOX pathway. …”
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Effect of Short-Term Stress and Interaction of Salinity and Ammonia-N Levels, Associated With Food Deprivation on Fatty Acid Profile and Body Composition in Nile Tilapia (Oreochrom...
Published 2025-01-01“…In salinity treatments and ammonia levels (50% and 30% of LC50-96 h of ammonia-N), a significant increase in the percentage of lipid, highly unsaturated fatty acids (HUFA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA) was observed. To draw the conclusion, our assessment indicates that a salinity concentration of 8 ppt over a 96-h period without feeding has produced positive effects on the quality of tilapia carcasses.…”
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Dietary (n-6 : n-3) Fatty Acids Alter Plasma and Tissue Fatty Acid Composition in Pregnant Sprague Dawley Rats
Published 2012-01-01“…The Diet 1 : 1 group showed significantly greater percentages of total n-3 PUFA and docosahexaenoic acid in adipose and liver tissue, and this clearly reflected the contribution of n-3 fatty acids from CLO. …”
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Investigation of Growth Performance, Proximate and Fatty Acid Composition of Freshwater (Euglena gracilis, Chlorella vulgaris) and Marine (Pavlova lutheri, Diacronema vlkanium) Mic...
Published 2024-01-01“…The highest EPA (C20:5n-3) content was found in Pavlova lutheri (6.85%) whereas arachidonic acid (C20:4n-6) and docosahexaenoic acid (C22:6n-3) contents were only found with a level of (3.32%) and (1.79%) in Euglena gracilis, respectively. …”
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Fatty Acids in Cnidaria: Distribution and Specific Functions
Published 2025-01-01“…Many of the families have characteristic FAs: Acroporidae are characterized by 18:3n6, eicosapentaenoic acid (EPA) 20:5n3, 22:4n6, and 22:5n3; Pocilloporidae by 20:3n6, 20:4n3, and docosahexaenoic acid 22:6n3 (DHA); and Poritidae by arachidonic acid (AA) and DHA. …”
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Omega-3 Polyunsaturated Fatty Acids Enhance Neuronal Differentiation in Cultured Rat Neural Stem Cells
Published 2013-01-01“…We recently reported that docosahexaenoic acid (DHA) induced neuronal differentiation by decreasing Hes1 expression and increasing p27kip1 expression, which causes cell cycle arrest in neural stem cells (NSCs). …”
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Relationship of Dietary Intake of Omega-3 and Omega-6 Fatty Acids with Risk of Prostate Cancer Development: A Meta-Analysis of Prospective Studies and Review of Literature
Published 2012-01-01“…Likewise, a slightly positive association was noted on dietary long-chain n-3 PUFA, composed of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) with prostate cancer risk (pooled RR: 1.135; 95% CI: 1.008, 1.278; ); however, when two other cohort studies with data of EPA and DHA, both analyzed separately, were included into the pool, the association became not significant (RR: 1.034; 95% CI: 0.973, 1.096; ). …”
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Effect of peppermint oil (mentha piperita) supplementation in quail diets on egg production and some egg quality characteristics, oxidative stress parameters and lipid profile
Published 2024-12-01“…A significant increase in omega-3 fatty acids, especially eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), was observed in the high-dose peppermint oil group, indicating an improvement in the lipid profile. …”
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