Screening for creatine transporter deficiency in autism spectrum disorder: a pilot study by Arslan Mutluay, Yildiz Yılmaz, Olgaç Asburçe, Hekim Özlem, Yücel Çiğdem, Sertoğlu Erdim

“…X-linked creatine transporter deficiency is among the metabolic disorders which may present predominantly with features of ASD and intellectual disability. Here, we aimed to screen for creatine transporter deficiency in boys with ASD at a university hospital in Turkey.…”
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Cervical Spondylotic Myelopathy: Factors in Choosing the Surgical Approach by Praveen K. Yalamanchili, Michael J. Vives, Saad B. Chaudhary

“…Cervical spondylotic myelopathy is a progressive disease and a common cause of acquired disability in the elderly. A variety of surgical interventions are available to halt or improve progression of the disease. …”
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Sturge–Weber Syndrome with Bilateral Port-Wine Stain by Bishnu Deep Pathak, Shriya Sharma, Aakriti Adhikari, Nabin Simkhada, Bhuwan Ghimire, Nirjala Aryal

“…Here, we describe a case of four years seven months female with seizures, developmental delay, intellectual disability, and bilateral port-wine stain diagnosed as type I (classical) Sturge–Weber syndrome. …”
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Linguistic Validation of the Kannada Language Version of Pelvic Girdle Questionnaire by Nice Mathew, Veena Kiran Nambiar, Jyothi GS

“…Categorically the internal consistency for the activity subscale 1-20 was 0.860 while that of the symptoms subscale 21-25 was 0.804.Conclusion The PGQ-Kannada is a reliable and valid tool with high internal consistency for assessing disability resulting from pelvic girdle pain in gravid women. …”
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Failed back surgery syndrome treatment using spinal cord stimulation in Lithuania by M. Vaišvilas, A. Radžiūnas, V. Deltuva, A. Tamašauskas

“…Many of the treated patients become unable to work because of their disability and face psychosocial problems. Failed Back Surgery Syndrome is defined as persisting chronic neuropathic pain after a successful lumbar spine surgery. …”
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Advances in Vertebral Augmentation Systems for Osteoporotic Vertebral Compression Fractures by Yufeng Long, Weihong Yi, Dazhi Yang

“…Osteoporotic vertebral compression fracture (OVCF) is a common cause of pain and disability and is steadily increasing due to the growth of the elderly population. …”
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The Usefulness of the Discrete Choice Experiment in Providing Effective Healthcare by Nikolina Dukić

“…Given that in times of crisis the burden of chronic disease is increasing, preventive interventions are becoming more important as they affect the maintenance and improvement of the population’s health, therefore reducing government spending on the sick leave and disability benefits. As public healthcare is characterized by administrative decision-making and relying on non-market mechanisms in the resource allocation, it requires the implementation of economic evaluations. …”
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Suicidality and Self-Harming Behaviors in Patients with Prader-Willi Syndrome (PWS): Case Report and Literature Review by Val Bellman, Zargham Abbass, Ramsa Sohail, Syed Jafri

“…Although PWS is associated with mild intellectual disability, which in itself confers a higher mortality rate, suicidality in this population is so far unreported in the literature. …”
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MicroRNAs in Cerebral Ischemia by Yang Wang, Yongting Wang, Guo-Yuan Yang

“…The risk of ischemic stroke increases substantially with age, making it the third leading cause of death and the leading cause of long-term disability in the world. Numerous studies demonstrated that genes, RNAs, and proteins are involved in the occurrence and development of stroke. …”
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Platelet-rich Plasma Therapy as a Treatment for Unilateral Foot Pain in a Child by Aanchal Sharma, Akhil Bhalla, Ishwar Bohra

“…Lateral sprains have been commonly seen in ankle injuries and have been the leading cause of chronic pain, disability, and posttraumatic ankle osteoarthritis. …”
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Klippel-Trenaunay-Weber Syndrome. Case Report and Literature Review by Laura Vázquez Pis, Maday González Hernández, Aimé Marrero Gil, Antonio Mazot Rangel

“…The treatment of choice is the symptomatic clinic, focused on avoiding disability, improving functional capacity, quality of life and preventing complications. …”
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Treatment of an ankle fracture-dislocation using RALCA external fixation. Five-year monitoring by Yaniel Truffin Rodriguez, Osmany Pérez Martínez, Annia L. López Hernández

“…Complications related to the non-reduction of a dislocation in the previously mentioned period of time are known; within these, avascular necrosis of the talus represents the most feared due to the disability it generates. For these reasons, it was decided to present a case that shows the treatment of a fracture -luxation of the right ankle, in a 30-year-old patient, stabilized by using a RALCA mini fixator, which was followed for a period of five years.…”
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THE FEELING UNDERSTANDING AND VALUES OF THE DEAF CHILDREN by Qurrata 'Ain, Margana Margana

“…It can be helped the deaf children to understand the signs. The disability people or gift children have an equal with normal people. …”
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Inflammation in Heart Failure: Mechanisms and Therapeutic Strategies by Jiang Yu, Guoxiang Zhou, Yongzheng Guo, Yang Long

“…Cardiovascular disease remains a leading cause of death and disability worldwide. Heart failure (HF) is the end stage of various cardiovascular diseases. …”
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Targeted Therapy for Rheumatoid Arthritis in the New Era by WANG Jun, MENG Juan

“…Ineffective drug treatment for severe arthritis can result in physical disability and severely decreased quality of life. In recent years, targeted therapy for RA has become a hot research topic and has made new breakthroughs. …”
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Sex Differences in Parkinson’s Disease: A Narrative Review by Carlo Cattaneo, Javier Pagonabarraga

“…The results confirm the existence of differences between men and women in PD; women have a higher risk of developing disabling motor complications and non-motor fluctuations compared to men, while men have a higher risk of developing cognitive impairment, postural instability, and gait disorders. …”
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Vibration Energy Color Doppler Imaging (VECDI) in Evaluating the Effect of Screw Fixation on Sacroiliac Joint Stiffness: A Prospective Pilot Study by Caleb Gottlich, Thomas Githens, Alex Drusch, Neil Jain, Cyrus Caroom, Phillip S. Sizer

“…Pearson correlation coefficients highlighted relationships between current pain at T1 and T2 (p = .004, r = .879), and Oswestry Disability Index (ODI) values at T1 and T2 (p = .003, r = .890). …”
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Traditional Chinese Mind and Body Exercises for Neck Pain: A Meta-Analysis of Randomized Controlled Trials by Yu-Hua Xie, Man-Xia Liao, Mao-Yuan Wang, W. C. Hewith A. Fernando, Yue-Ming Gu, Xue-Qiang Wang, Lin-Rong Liao

“…Compared with the control groups, TCMBE had no therapeutic advantage in improving pain intensity (visual analogue scale: mean difference (MD) = 1.8, 95% confidence interval (CI): −7.70 to 11.46, and P = 0.70); functional mobility (neck disability index: MD = 0.15, 95% CI: −6.37 to 6.66, and P = 0.96; neck pain and disability scale: MD = 1.31, 95% CI: −4.10 to 6.71, and P = 0.64); or 36-item short-form health survey (SF-36) scores for physical function (MD = 5.58, 95% CI: −8.03 to 19.18, and P = 0.42), general health (MD = 1.87, 95% CI: −4.99 to 8.72, and P = 0.59), body pain (MD = 2.26, 95% CI: −3.80 to 8.32, and P = 0.46), vitality (MD = 6.24, 95% CI: −1.49 to 13.98, and P = 0.11), social function (MD = 8.06, 95% CI: −4.85 to 20.98, and P = 0.22), role physical (MD = –1.46, 95% CI: −8.54 to 5.62, and P = 0.69), or role emotional (MD = 6.5, 95% CI: −3.45 to 16.45, and P = 0.2). …”
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Evaluation of a Guided Chatbot Intervention for Young People in Jordan: Feasibility Randomized Controlled Trial by Anne Marijn de Graaff, Rand Habashneh, Sarah Fanatseh, Dharani Keyan, Aemal Akhtar, Adnan Abualhaija, Muhannad Faroun, Ibrahim Said Aqel, Latefa Dardas, Chiara Servili, Mark van Ommeren, Richard Bryant, Kenneth Carswell

“… BackgroundDepression and anxiety are a leading cause of disability worldwide and often start during adolescence and young adulthood. …”
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Using the Oxford Foot Model to determine the association between objective measures of foot function and results of the AOFAS Ankle-Hindfoot Scale and the Foot Function Index: a pr... by Frank Krummenauer, Tanja Kostuj, Felix Stief, Kirsten Anna Hartmann, Katharina Schaper, Mohammad Arabmotlagh, Mike H Baums, Andrea Meurer, Sebastian Lieske

“…An analysis of correlations with CIs between the FFI-D and the AOFAS-AHS items and the gait parameters was performed by means of the Jonckheere-Terpstra test; furthermore, exploratory factor analysis was applied to identify common information structures and thereby redundancy in the FFI-D and the AOFAS-AHS items.Results Objective findings for hindfoot disorders, namely a reduced ROM, in the ankle and subtalar joints, respectively, as well as reduced ankle power generation during push-off, showed a better correlation with the AOFAS-AHS total score—as well as AOFAS-AHS items representing ROM in the ankle, subtalar joints and gait function—compared with the FFI-D score.Factor analysis, however, could not identify FFI-D items consistently related to these three indicator parameters (pain, disability and function) found in the AOFAS-AHS. Furthermore, factor analysis did not support stratification of the FFI-D into two subscales.Conclusions The AOFAS-AHS showed a good agreement with objective gait parameters and is therefore better suited to evaluate disability and functional limitations of patients suffering from foot and ankle pathologies compared with the FFI-D.…”
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