Utilizing machine-learning techniques on MRI radiomics to identify primary tumors in brain metastases by W. L. Yang, W. L. Yang, X. R. Su, S. Li, K. Y. Zhao, Q. Yue

“…A comprehensive model combining radiomics and clinical features was established, and the diagnostic performance was compared by area under the curve (AUC) and evaluated in an independent test set.ResultsThe radiomics model differentiated BMGiT from BMLC (13 features, AUC = 0.915 ± 0.071) or BMBC (20 features, AUC = 0.954 ± 0.064) with high accuracy, while the classification between BMLC and BMBC was unsatisfactory (11 features, AUC = 0.729 ± 0.114). …”
Get full text

Leptomeningeal Dissemination in Choroid Plexus Tumors: Magnetic Resonance Imaging Appearance and Risk Factors by Daniel Nunes do Espirito Santo, Monika Warmuth-Metz, Camelia-Maria Monoranu, Martin Hasselblatt, Christian Thomas, Torsten Pietsch, Jürgen Krauß, Tilmann Schweitzer, Brigitte Bison, Matthias Eyrich, Uwe Kordes, Denise Obrecht-Sturm, Mirko Pham, Annika Quenzer

Get full text

Burden of Antimicrobial Resistance in Adult Hospitalized Patients With Cancer: A Multicenter Analysis by Vikas Gupta, Michael J. Satlin, Kalvin Yu, Yehoda M. Martei, Lillian Sung, Lars F. Westblade, Scott C. Howard, ChinEn Ai, Diane C. Flayhart

“…The increased AMR rate in cancer patients highlights the need for enhanced infection prevention and diagnostic stewardship efforts.…”
Get full text

Assessment of the application of the FA280—a fully automated fecal analyzer for diagnosing clonorchiasis: a mixed-method study by Si-Yue Huang, Qing-Sheng Zeng, Xin-Fu Shi, Yun-Ting He, Yue-Yi Fang, Ying-Si Lai

“…The quantitative component consisted of a cross-sectional survey in Xinhui District, Guangdong, China, to evaluate the diagnostic performance of the FA280. The positive rate and agreement between the FA280 and the KK method were evaluated using McNemar’s test. …”
Get full text

Role of the androgen receptor in melanoma aggressiveness by Marzia Di Donato, Costanza Maria Cristiani, Mariaelena Capone, Cinzia Garofalo, Gabriele Madonna, Lucia Carmela Passacatini, Margaret Ottaviano, Paolo Antonio Ascierto, Ferdinando Auricchio, Ennio Carbone, Antimo Migliaccio, Gabriella Castoria

“…Taken together, our findings identify the androgen receptor as a diagnostic guidance in melanoma and support the repositioning of AR blockers in clinical management of patients.…”
Get full text

Maximizing the clinical utility and performance of cytology samples for comprehensive genetic profiling by David Kim, Chad M. Vanderbilt, Soo-Ryum Yang, Subhiksha Nandakumar, Khedoudja Nafa, Rusmir Feratovic, Natasha Rekhtman, Ivelise Rijo, Jacklyn Casanova, Anita Yun, A. Rose Brannon, Michael F. Berger, Marc Ladanyi, Oscar Lin, Maria E. Arcila

“…However, routine implementation is challenged by the scant nature of diagnostic material obtained through minimally invasive procedures. …”
Get full text

Relationship between cognitive impairment and hippocampal iron overload: A quantitative susceptibility mapping study of a rat model by Xi Deng, Meiru Bu, Jiali Liang, Yihao Sun, Liyan Li, Heishu Zheng, Zisan Zeng, Muliang Jiang, Bihong T. Chen

Get full text

The Use of AI in Mental Health Services to Support Decision-Making: Scoping Review by Hassan Auf, Petra Svedberg, Jens Nygren, Monika Nair, Lina E Lundgren

“…Three types of AI systems were identified in terms of decision-making support: diagnostic and predictive AI, treatment selection AI, and self-help AI. …”
Get full text

Clinical Evaluation of a Rapid Reciprocal-Flow PCR Assay and Real-Time PCR Assay with Quenching Probe for Detection of <i>Mycobacterium tuberculosis</i> Complex by Kosuke Kosai, Keisuke Matsumoto, Takahisa Ishikawa, Yasuhide Kawamoto, Norihiko Akamatsu, Kenji Ota, Fujiko Mitsumoto-Kaseida, Norihito Kaku, Hiroo Hasegawa, Koichi Izumikawa, Hiroshi Mukae, Katsunori Yanagihara

“…This study investigated the diagnostic efficiencies of two assays for the detection of <i>Mycobacterium tuberculosis</i> complex: (1) the reciprocal-flow real-time polymerase chain reaction (PCR)-based GeneSoC assay and (2) the real-time PCR based GENECUBE MTB assay with quenching probe. …”
Get full text

Molecular Epidemiological Characteristics of <i>Staphylococcus pseudintermedius</i>, <i>Staphylococcus coagulans,</i> and Coagulase-Negative Staphylococci Cultured from Clinical Ca... by Sara Horsman, Julian Zaugg, Erika Meler, Deirdre Mikkelsen, Ricardo J. Soares Magalhães, Justine S. Gibson

“…<b>Methods:</b> Forty-two <i>Staphylococcus</i> spp. isolated from clinical canine skin and ear samples, from an unknown number of dogs, were sourced from two veterinary diagnostic laboratories between January 2022 and May 2023. …”
Get full text

Study on exhaled volatile organic compounds identifying cognitive fatigue induced by N-back task in healthy young adults by Xiaoyu Zhang, Xiaoyan Dong, Qiang Huang, Zhe Liu, Qin Wang

“…The study aimed to explore the characteristic volatile organic compounds (VOCs) in exhaled breath in response to cognitive fatigue, to provide a scientific basis for the non-invasive exhaled breath diagnostic techniques for cognitive fatigue assessing. …”
Get full text

Association between Axial Length to Corneal Curvature Radius Ratio and Myopia in Adult Patients by Yanyun Fan, Yikeng Huang, Xionggao Huang

“…Compared with 0.830 (95% confidence interval: 0.769 to 0.900) for AL, the area under ROC curve of AL/CR was 0.896 (95% confidence interval: 0.851 to 0.941), indicating that the diagnostic value of AL/CR for high myopia was higher than that of AL (P< 0.01). …”
Get full text

System- and fish-size-specific reference intervals for plasma analytes in Atlantic salmon (Salmo salar L.) reared in commercial fresh- and saltwater recirculating aquaculture syste... by Thomas Amlie, David Persson, Simen Foyn Nørstebø, Asgeir Østvik, Marit Stormoen, Øystein Evensen

“…Reference values should then be compared to analyte levels in fish with known diseases to assess the diagnostic value of blood sampling.…”
Get full text

Aetiology of vaginal discharge, urethral discharge, and genital ulcer in sub-Saharan Africa: A systematic review and meta-regression. by Julia Michalow, Magdalene K Walters, Olanrewaju Edun, Max Wybrant, Bethan Davies, Tendesayi Kufa, Thabitha Mathega, Sungai T Chabata, Frances M Cowan, Anne Cori, Marie-Claude Boily, Jeffrey W Imai-Eaton

“…<h4>Background</h4>Syndromic management is widely used to treat symptomatic sexually transmitted infections in settings without aetiologic diagnostics. However, underlying aetiologies and consequent treatment suitability are uncertain without regular assessment. …”
Get full text

Thrombophilia screening in women with recurrent first trimester miscarriage: is it time to stop testing? – a cohort study and systematic review of the literature by Hassan Shehata, Ranjit Akolekar, Amanda Ali, Mariane Silva-Edge, Shahla Haroon, Abdullatif Elfituri, Radhika Viswanatha, Haider Jan

“…The objective of our study was to assess the prevalence of inherited and acquired thrombophilia in a large cohort of women with a history of early RM using internationally agreed diagnostic criteria and inclusion parameters and compare it to the meta-analysis results of existing literature.Methods Design Retrospective cohort study and systematic review of literature.Setting This is a retrospective cohort study set-up in two dedicated tertiary centres for women with RM in Southwest London and Surrey. …”
Get full text

CST2 promotes cell proliferation and regulates cell cycle by activating Wnt-β-catenin signalling pathway in serous ovarian cancer by Xiaohua Wang, Sufen Zhao, Yanwei Guo, Chunhui Wang, Shuyu Han, Xingcha Wang

“…Additionally, our findings suggest that CST2 is a promising novel biomarker with potential applications in therapeutic, prognostic, and diagnostic strategies for SOC.…”
Get full text

COVID-19 is a risk factor for retinal vein occlusion in younger patients? by A.G. Shchuko, M.V. Akulenko, T.N. Yur’eva

“…Management of younger patients with RVO required a complex diagnostic approach to assess systemic risk factors and obligatory evaluation of baseline retinal ischemia using fluorescein angiography (FA) or optical coherence tomography angiography (OCTA). …”
Get full text

Identification and Analysis of Potential Immune-Related Biomarkers in Endometriosis by Yanan He, Jixin Li, Yanjun Qu, Liyuan Sun, Xibo Zhao, Han Wu, Guangmei Zhang

“…Finally, the receiver operating characteristic (ROC) curve analysis was used to assess the diagnostic value of the hub IRGs. Results. We screened a total of 94 DETFs and 121 DEIRGs in endometriosis. …”
Get full text

Maternal health risk factors dataset: Clinical parameters and insights from rural BangladeshMendeley Data by Mayen Uddin Mojumdar, Dhiman Sarker, Md Assaduzzaman, Hasin Arman Shifa, Md. Anisul Haque Sajeeb, Oahidul Islam, Md Shadikul Bari, Mohammad Jahangir Alam, Narayan Ranjan Chakraborty

“…In summary, this database will be highly valued and a significant asset for research studies on maternal health in pregnant patients, public health strategies, and the enhancing diagnostic and treatment modalities for patients.…”
Get full text

Diagnosis of Schizophrenia and Its Subtypes Using MRI and Machine Learning by Hosna Tavakoli, Reza Rostami, Reza Shalbaf, Mohammad‐Reza Nazem‐Zadeh

“…Conclusion The findings of this study underscore the utility of MRI and ML algorithms in enhancing the diagnostic process for schizophrenia. Furthermore, these methods hold promise for detecting both brain‐related abnormalities and cognitive impairments associated with this disorder.…”
Get full text