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44501
A sea ice deformation and rotation rate dataset (2017–2023) from the Environment and Climate Change Canada automated sea ice tracking system (ECCC-ASITS)
Published 2025-02-01“…The spatial coverage and range of resolutions of the SIDRR dataset provide an interesting opportunity to investigate regional and seasonal variability in sea ice deformation statistics across scales, and these data can also be used to determine metrics for model evaluation.</p>…”
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44502
Variables associated with cognitive function: an exposome-wide and mendelian randomization analysis
Published 2025-01-01“…Abstract Background Evidence indicates that cognitive function is influenced by potential environmental factors. We aimed to determine the variables influencing cognitive function. …”
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44503
mRNA-LNP vaccines combined with tPA signal sequence elicit strong protective immunity against Klebsiella pneumoniae
Published 2025-01-01“…Adaptive immunity was determined in mRNA vaccines-immunized mice and the protective effects of mRNA vaccines were evaluated in K. pneumoniae infected models. …”
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44504
Anthropometric measurements as markers of elevated blood pressure among Portuguese children and adolescents
Published 2025-02-01“…Receiver operating characteristic (ROC) analysis was used to determine the predictive capacity each of these measurements for identifying individuals with elevated BP. …”
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44505
Knowledge, attitudes and practices of healthcare workers towards COVID-19 in three states of Nigeria in 2022
Published 2025-01-01“…Binary logistic regression was used to determine the association between HCWs’ cadre and satisfactory KAP.Results The proportions of HCW with satisfactory KAP were 64.5%, 51.2% and 5.3%, respectively. …”
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44506
Exploring the allometry between ear saturated water accumulation and dry mass for diagnosing winter wheat water status during the reproductive growth
Published 2025-03-01“…Field experiments involving four water and two nitrogen treatments were conducted from 2019 to 2023 to determine the relationship between ear dry mass (EDM) and SWAE during the reproductive growth phase of winter wheat. …”
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44507
Informatization of the processes of administration of the quality of medical services in surgical hospitals
Published 2024-10-01“…Currently, there is no comprehensive information technology and algorithm for recording data on the provision of medical services and determining their quality. The goal is to develop and analyze the effectiveness of business processes and an algorithm for quality control of the performance of medical services in a surgical health care institution by establishing their daily accounting in the information system, control of indicators characterizing the safety and quality of their performance, as well as an opportunity to assess the dynamics changes in indicators for making management decisions. …”
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44508
Application of additive manufacturing for the adaptive design of ultrasound phantoms
Published 2025-01-01“…Speed of sound and attenuation were determined for both phantoms materials, and Shore hardness measured for the PVA-based phantoms.ResultsShore hardness of the PVA phantoms increased by up to 79% of the initial value with increasing number of freeze-thaw cycles, but showed a saturation after 5 FTCs. …”
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44509
<i>Vismia guianensis</i> Improves Survival of <i>Tenebrio molitor</i> and Mice During Lethal Infection with <i>Candida albicans</i>
Published 2025-01-01“…In the mice, the antifungal effect of EHVG was determined in three groups of immunosuppressed Swiss mice (cyclophosphamide, 50 mg/kg/ip) infected with <i>C. albicans</i> (1 × 10<sup>7</sup> CFU/ip). …”
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44510
Evaluation of Native <em>Festuca</em> Taxa for Sustainable Application in Urban Environments: Their Characteristics, Ornamental Value, and Germination in Different Growing Media
Published 2024-09-01“…During this study, <i>Festuca wagneri</i> and <i>Festuca tomanii</i> were identified as potentially suitable grass species for urban planting and turf establishment based on preliminary research. Our aim was to determine the germination success of seeds from aesthetically selected individuals and to identify the growing media on which they germinate most effectively. …”
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44511
Systematic ocular phenotyping of 8,707 knockout mouse lines identifies genes associated with abnormal corneal phenotypes
Published 2025-01-01“…A literature search was used to determine the proportion of candidate genes previously associated with CDs in mice and humans. …”
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44512
Whole genome sequencing of a novel carrageenan-degrading bacterium Photobacterium rosenbergii and oligosaccharide preparation
Published 2025-01-01“…Optimal hydrolysis conditions were determined to be 40°C and pH 7.0, with the enzyme retaining 80% of its activity below 30°C and across a pH range of 4.0–10.0. …”
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44513
Longitudinal immunogenicity cohort study of SARS-CoV-2 mRNA vaccines across individuals with different immunocompromising conditions: heterogeneity in the immune response and cruci...
Published 2025-03-01“…Summary: Background: Individuals with primary and secondary immunodeficiencies, being more susceptible to infections, are a priority for vaccination. Here, we determined and compared in a longitudinal study the immune response elicited by SARS-CoV-2 vaccination across different groups of individuals who are immunocompromised. …”
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44514
Comprehensive analysis of antimicrobial resistance dynamics among broiler and duck intensive production systems
Published 2025-02-01“…Above-average resistance markers accounted for approximately 10% of all detected resistance determinants. Tetracycline and phenicol resistances emerged as the most prevalent. 13 high-resistance carrier (HRC) species were shared between both hosts. …”
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44515
Long non-coding RNA Malat1 modulates CXCR4 expression to regulate the interaction between induced neural stem cells and microglia following closed head injury
Published 2025-01-01“…Student’s t-test and one-way analysis of variance (ANOVA) with Tukey’s post hoc test were used to determine statistical significance. Results Our results indicated that Malat1 could act as a sponge of miR-139-5p to modulate the expression of CXCR4 that exerted significant influence on the immunoregulatory effects of iNSCs on the secretion of CXCL12, TNF-α and IGF-1 by activated microglia. …”
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44516
Identifying biomarker-driven subphenotypes of cardiogenic shock: analysis of prospective cohorts and randomized controlled trialsResearch in context
Published 2025-01-01“…Methods: We used unsupervised clustering to integrate plasma biomarker data from two prospective cohorts of CS patients: CardShock (N = 205 [2010–2012, NCT01374867]) and the French and European Outcome reGistry in Intensive Care Units (FROG-ICU) (N = 228 [2011–2013, NCT01367093]) to determine the optimal number of classes. Thereafter, a simplified classifier (Euclidean distances) was used to assign the identified CS subphenotypes in three completed randomized controlled trials (RCTs) (OptimaCC, N = 57 [2011–2016, NCT01367743]; DOREMI, N = 192 [2017–2020, NCT03207165]; and CULPRIT-SHOCK, N = 434 [2013–2017, NCT01927549]) and explore heterogeneity of treatment effect with respect to 28-day mortality (primary outcome). …”
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44517
Comprehensive genomic and transcriptomic profiling of pulmonary nodules in synchronous multiple primary lung cancer
Published 2025-02-01“…The multiple nodules from the same patient was determined as major nodule and minor nodule. Additionally, the tumor tissues underwent histopathological evaluation through H&E staining, complemented by a comprehensive series of immunohistochemistry (IHC) analyses to detect protein expression. …”
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44518
CT45A1‐mediated MLC2 (MYL9) phosphorylation promotes natural killer cell resistance and outer cell fate in a cell‐in‐cell structure, potentiating the progression of microsatellite...
Published 2025-02-01“…We aimed to identify the tumor‐autonomous regulators determining these heterogeneous clinical outcomes. The Cancer Genome Atlas (TCGA) dataset was used to identify regulators in MSI‐H CRC patients with unfavorable outcomes. …”
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44519
Catabolic pathway acquisition by rhizosphere bacteria readily enables growth with a root exudate component but does not affect root colonization
Published 2025-01-01“…To experimentally test the effects of pathway acquisition, we transferred a pathway for catabolism of a plant-derived aromatic compound between soil bacteria isolated from the roots of poplar trees and determined the resulting phenotypic and fitness effects. …”
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44520
Adenomas from individuals with pathogenic biallelic variants in the MUTYH and NTHL1 genes demonstrate base excision repair tumour mutational signature profiles similar to colorecta...
Published 2025-02-01“…Background: Colorectal cancers (CRCs) from people with biallelic germline likely pathogenic/pathogenic variants in MUTYH or NTHL1 exhibit specific single base substitution (SBS) mutational signatures, namely combined SBS18 and SBS36 (SBS18+SBS36), and SBS30, respectively. The aim was to determine if adenomas from biallelic cases demonstrated these mutational signatures at diagnostic levels. …”
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