Optimized methods for the targeted surveillance of extended-spectrum beta-lactamase-producing Escherichia coli in human stool by Sarah Gallichan, Sally Forrest, Esther Picton-Barlow, Claudia McKeown, Maria Moore, Eva Heinz, Nicholas A. Feasey, Joseph M. Lewis, Fabrice E. Graf

“…Here, we compared different steps in the microbiological workflow to determine the impact different pre-enrichment broths, pre-enrichment incubation times, selection in pre-enrichment, selective plating, and DNA extraction methods had on recovering ESBL-EC from human stool samples, with the aim to acquire high-quality DNA for sequencing and genomic epidemiology. …”
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Virulence potential of faecal <i>Escherichia coli</i> strains isolated from healthy cows and calves on farms in Perm Krai by V. S. Mihailovskaya, N. B. Remezovskaya, I. N. Zhdanova, M. Starčič Erjavec, M. V. Kuznetsova

“…The presence of VAGs that are common among diarrheagenic E. coli (DEC) strains and/or extraintestinal pathogenic E. coli (ExPEC) strains was determined by amplifying specific gene sequences by PCR. …”
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Segmentasi Pelanggan B2B dengan Model LRFM Menggunakan Algoritma Fuzzy C-Means pada Rotte Bakery by Dea Putri Ananda, Siti Monalisa

“…The Davies Bouldien-Index validation method was used to determine the optimal number of clusters. The results revealed that there are five optimal clusters for agent customers with a DBI value of 0.57, while outlet customers have four clusters with a DBI value of 0.49. …”
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Decidualized ovarian and rectouterine deep endometriosis disguised as malignancy in the second-trimester of pregnancy: A case report by Lingjie Bao, Ting Wang, Yinping Xiao, Shouxin Gu, Xiaoyu Zhou, Yunxi Zheng, Yun Chen, Xiaofang Yi

“…Conservative laparoscopic surgery was suggested to determine the pathology first. When removing the ovarian cysts and the lesion at rectouterine pouch, rich papillary nodules inside the capsule were exposed and looked like malignancy. …”
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Development of Cephradine-Loaded Gelatin/Polyvinyl Alcohol Electrospun Nanofibers for Effective Diabetic Wound Healing: In-Vitro and In-Vivo Assessments by Anam Razzaq, Zaheer Ullah Khan, Aasim Saeed, Kiramat Ali Shah, Naveed Ullah Khan, Bouzid Menaa, Haroon Iqbal, Farid Menaa

“…The resulting drug-loaded NFs (LNFs) were characterized physically using ultraviolet-visible (UV-Vis) spectrophotometry (for drug loading capacity (LC), drug encapsulation efficiency (EE), and drug release kinetics determination), thermogravimetric analysis (TGA) (for thermostability evaluation), scanning electron microscopy (SEM) (for surface morphology analysis), and Fourier-transform infrared spectroscopy (FTIR) (for functional group identification). …”
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Systemic Resolvin E1 (RvE1) Treatment Does Not Ameliorate the Severity of Collagen-Induced Arthritis (CIA) in Mice: A Randomized, Prospective, and Controlled Proof of Concept Study by Rafael Scaf de Molon, Rogier M. Thurlings, Birgitte Walgreen, Monique M. Helsen, Peter M. van der Kraan, Joni Augusto Cirelli, Marije I. Koenders

“…Thus, this study is aimed at determining whether systemic RvE1 treatment reduces arthritis onset and severity in murine collagen-induced arthritis (CIA) and spontaneous cytokine production by human rheumatoid arthritis (RA) synovial explants. 10-week-old DBA1/J male mice were subjected to CIA and treated systemically with 0.1 μg RvE1, 1 μg RvE1, 5 mg/kg anti-TNF (positive control group), PBS (negative control group), or with a combination of 1 μg of RvE1 plus 5 mg/kg anti-TNF using prophylactic or therapeutic strategies. …”
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Game-thinking; utilizing serious games and gamification in nursing education – a systematic review and meta-analysis by Mats Nylén-Eriksen, Marko Stojiljkovic, Daniela Lillekroken, Katrin Lindeflaten, Elisabeth Hessevaagbakke, Tone Nygaard Flølo, Olav Johannes Hovland, Ada Marie Svarstad Solberg, Sylvia Hansen, Ann Kristin Bjørnnes, Christine Tørris

“…We aim to identify, assess, and summarize the findings of evidence and determine the effectiveness of game-thinking on learning outcomes in nursing education. …”
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Optimization of Preparation of Bioactive Peptide by Enzymatic Hydrolysis in <italic>Katsuwonus pelamis </italic>Using Response Surface Methodology and its Anti-fatigue Effect on Mi... by LI Shoujiang, KONG Xiangjia, LIU Zhiyu, ZHAO Feng, SU Yongchang, CHEN Xiaoting

“…Compared with the exercise model group, the exhaustion swimming time of the positive control group, low-, medium- and high-dose of bioactive peptide in <italic>Katsuwonus pelamis</italic> groups were significantly prolonged (<italic>P</italic>&lt;0.01), the contents of serum BUN, serum LD and liver MDA, and serum LDH activity were decreased (all <italic>P</italic>&lt;0.01), while the liver SOD activity was improved (<italic>P</italic>&lt;0.01).ConclusionThe response surface methodology was used to determine the optimal enzymatic hydrolysis technology of bioactive peptide in <italic>Katsuwonus pelamis</italic> with flavor protease, which verified that bioactive peptide in <italic>Katsuwonus pelamis</italic> could relieve fatigue in exhausted swimming mice.…”
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Designing host-associated microbiomes using the consumer/resource model by Germán Plata, Karthik Srinivasan, Madan Krishnamurthy, Lukas Herron, Purushottam Dixit

“…Using data from three animal hosts, we show that this mechanistic generative model has several salient features: the model identifies a latent space that represents variables that determine the growth and, therefore, relative abundances of microbial species. …”
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Mangrove biomass productivity and sediment carbon storage assessment at selected sites in Mauritius: the effect of tidal inundation, forest age and mineral availability by M D D Doodee, S D D V Rughooputh, S Jawaheer

“…Total organic carbon (TOC), sediment carbon storage, and all essential nutrients for plant growth were analysed using standard methods. Soil texture was determined using granulometric analysis. Our findings show that in both natural and planted forests, the zones that were more inundated were first established. …”
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Targeted inhibition of Aurora kinase A promotes immune checkpoint inhibition efficacy in human papillomavirus-driven cancers by Pragya Sinha, Faye M Johnson, Soma Ghosh, Jagannadha K Sastry, Madison P O'Hara, Tuhina Mazumdar, Lacin Yapindi

“…In each treatment group, we determined the tumor growth kinetics and long-term survival and assessed the tumor immune microenvironment using polychromatic flow cytometry.Results Aurora A inhibition induced apoptosis, DNA damage, and ICD in vitro in multiple human and murine HPV-positive cancer cell lines. …”
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Promoting trans patient autonomy in surgical preparation for phalloplasty and metoidioplasty: results from a community-based cross-sectional survey and implications for preoperativ... by Leo L. Rutherford, Elijah R. Castle, Noah Adams, Logan Berrian, Linden Jennings, Ayden Scheim, Aaron Devor, Nathan J. Lachowsky

“…Respect for patient autonomy is one of the central tenets of ethical healthcare, yet historically, scholarship related to pre-surgical assessments for gender-affirming surgery has focused determining the ideal surgical candidate rather than respecting patient autonomy and ascertaining individual patient needs. …”
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Factors associated with the injury severity of falls from a similar height and features of the injury site in Korea: a retrospective study by Dae Hyun Kim, Jae-Hyug Woo, Yang Bin Jeon, Jin-Seong Cho, Jae Ho Jang, Jea Yeon Choi, Woo Sung Choi

“…Purpose This study aimed to determine the risk factors associated with the severity of fall-related injuries among patients who suffered a fall from similar heights and analyze differences in injury sites according to intentionality and injury severity. …”
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Hubungan Kadar Hemoglobin Ibu Hamil Trimester III Dengan Berat Bayi Lahir di Kota Pariaman by Anggi Setiawan, Nur Indrawaty Lipoeto, Amirah Zatil Izzah

“…Kesimpulan: penelitian ini tidak ditemukan adanya hubungan kadar hemoglobin ibu hamil trimester III dengan berat bayi lahir di kota Pariaman (p &gt; 0,05)<br />Kata kunci: Kadar hemoglobin, berat bayi lahir, ibu hamil<br />Abstract<br />Introduction : Hemoglobin level is biochemical indicator to determine the nutrition status of pregnant women. World Health Organization (WHO) recommends that ideal level of hemoglobin for pregnant women is ≥ 11 g/dl and not below 10,5 g/dl on the second trimester of pregnancy. …”
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Peran Asupan Zat Gizi Makronutrien Ibu Hamil terhadap Berat Badan Lahir Bayi di Kota Padang by Mila Syari, Joserizal Serudji, Ulvi Mariati

“…</p><p> </p><p>Abstract <br />Growth and development of children determined by the condition of the fetus in the uterus and maternal dietary intake during pregnancy. …”
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Anti-inflammatory Effects of Empagliflozin and Gemigliptin on LPS-Stimulated Macrophage via the IKK/NF-κB, MKK7/JNK, and JAK2/STAT1 Signalling Pathways by Nami Lee, Yu Jung Heo, Sung-E Choi, Ja Young Jeon, Seung Jin Han, Dae Jung Kim, Yup Kang, Kwan Woo Lee, Hae Jin Kim

“…We conducted quantitative RT-PCR (qRT-PCR) to determine the most effective anti-inflammatory doses without cytotoxicity. …”
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Perfusion index as a predictor of successful PNS-guided supraclavicular block: A prospective study by Monika Gandhi, Khushboo Ranpise, Aseem Sharma, Manish Banjare

“…Objectives: The primary objective of this study was to assess the value of PI as a predictor of successful PNS-guided supraclavicular block and to determine threshold values for PI and PI ratio that could accurately predict block success. …”
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Redox-Modulating Capacity and Effect of Ethyl Acetate Roots and Aerial Parts Extracts from <i>Geum urbanum</i> L. on the Phenotype Inhibition of the <i>Pseudomonas aeruginosa</i> L... by Lyudmila Dimitrova, Milka Mileva, Almira Georgieva, Elina Tzvetanova, Milena Popova, Vassya Bankova, Hristo Najdenski

“…This study aimed to investigate the redox-modulating capacity and effect of ethyl acetate (EtOAc) extracts from roots (EtOAcR) and aerial parts (EtOAcAP) of the Bulgarian plant on the phenotype inhibition of the <i>P. aeruginosa</i> Las/RhI quorum sensing (QS) system, which primarily determines drug resistance in pathogenic bacteria, including biofilm formation, motility, and pigment production. …”
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Growth and Population Parameters of Panulirus penicillatus and Panulirus homarus in Labangka Tidal Waters, Indonesia by Evron Asrial, Erwin Rosadi, Hamid Hamid, Muhammad Ichsan, Ruly Isfatul Khasanah, Naning Dwi Sulystyaningsih, Agustin Dwi Sumiwi, Najiah Khalisah

“…The aim of this study is to determine the key attributes in growth and population parameters. …”
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Emulation of ARISTOTLE and ROCKET AF trials in real-world atrial fibrillation patients results in similar efficacy and safety as original landmark trials: insights from the GARFIEL... by Ralf E Harskamp, Karen Pieper, A John Camm, Ajay K Kakkar, Jelle C L Himmelreich, Saverio Virdone, Jean-Pierre Bassand, Frank Misselwitz, Freek W A Verheugt, Frank Cools, Harry Gibbs, Antônio C Pereira-Barretto

“…Aims This study aimed to determine the robustness, reproducibility and representativeness of the landmark Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation (AF) (ARISTOTLE) and Rivaroxaban Once Daily Oral Direct Factor Xa Inhibition Compared with Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in AF (ROCKET AF) randomised trials through replication in an observational AF patient registry.Methods and results Patients from the Global Anticoagulant Registry in the FIELD (GARFIELD)-AF registry treated with apixaban, rivaroxaban or vitamin K antagonist (VKA) were assessed for eligibility for the ARISTOTLE and ROCKET AF trials. …”
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