Beef cattle performance and hair cortisol accumulation in silvopastoral and pastoral systems: a 2-year assessment by A. Ripamonti, G. Foggi, A. Mantino, L. Turini, J. Goracci, A. Silvi, M. Finocchi, M. Mele

“…A decrease of glucose levels in PA group was determined but further research is needed to clarify the effects of heat stress on physiological mechanisms that lead to a change in glucose levels. …”
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Plasma prolactin axis shift from placental to pituitary origin in late prepartum mice by Taku James Sairenji, Shinnosuke Masuda, Yuya Higuchi, Mitsue Miyazaki, Hiroyuki Yajima, Oh Kwan Ee, Yuki Fujiwara, Takuya Araki, Noriaki Shimokawa, Noriyuki Koibuchi

“…The level of Prl3b1 mRNA was determined by RT-qPCR in the placenta and remained stable until parturition, implying that PRL3B1 peptide production or secretion was suppressed. …”
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Combining In Vitro, In Vivo, and In Silico Approaches to Explore the Effect of <i>Ceratonia siliqua</i> and <i>Ocimum basilicum</i> Rich Phenolic Formula on Lipid Metabolism and Pl... by Mohammadine Moumou, Amani Tayebi, Abderrahmane Hadini, Omar M. Noman, Abdulsalam Alhalmi, Hamza Ahmoda, Souliman Amrani, Hicham Harnafi

“…Methods: The phenolic composition was determined using HPLC-DAD analysis. The antioxidant activity was studied using various in vitro methods. …”
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Epidemiological Characteristics and Prognostic Scoring in Toxic Epidermal Necrolysis and Stevens–Johnson Syndrome: Insights from a 17-Year Burn Center Experience by David Breidung, Sarina Delavari, Ioannis-Fivos Megas, Alexander Geierlehner, Wolfgang Hitzl, Karl J. Bodenschatz, Konrad Karcz, Denis Ehrl, Moritz Billner

“…A classification tree was created to detect unknown determinants of SJS/TEN mortality. <i>Results</i>: The drug most frequently associated with the occurrence of SJS/TEN was metamizole. …”
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Does syndromic surveillance assist public health practice in early detecting respiratory epidemics? Evidence from a wide Italian retrospective experience by Giovanni Corrao, Andrea Stella Bonaugurio, Giorgio Bagarella, Mauro Maistrello, Olivia Leoni, Danilo Cereda, Andrea Gori

“…Methods: Healthcare Utilization databases of the Italian region of Lombardy and the Google Trends website were used to measure the weekly utilization of emergency and healthcare services and determining the volume of Google searches from 2020 to 2022. …”
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The effectiveness and risks of Treating people with Idiopathic Pulmonary fibrosis with the Addition of Lansoprazole (TIPAL): study protocol for a randomised placebo-controlled mult... by Toby M Maher, A John Simpson, Anthony Cahn, David Thickett, Luke Vale, Allan B Clark, Nazia Chaudhuri, Ian Forrest, Lisa G Spencer, Christopher Ward, Stephen Jones, Ganesh Raghu, Andrew M Wilson, Helen Parfrey, Megan Jones, Matthew Hammond, Jaclyn Ann Smith, Shajahan Wahed

“…The trial is designed to determine whether treating people with IPF with lansoprazole will reduce the reduction in FVC over a year. …”
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Pneumonia among Under-Five Children in Northwest Ethiopia: Prevalence and Predictors—A Community-Based Cross-Sectional Study by Zewudu Andualem, Tsegaye Adane, Abiye Tigabu, Walelign Worku Yallew, Sintayehu Daba Wami, Henok Dagne, Jember Azanaw, Gebisa Guyasa, Zelalem Nigussie Azene, Mastewal Endalew

“…The current study is aimed at determining the magnitude and risk factors of childhood pneumonia in Gondar City. …”
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Cytoreductive Nephrectomy and Nephrectomy/Complete Metastasectomy for Metastatic Renal Cancer by Paul Russo, Mark Synder, Andrew Vickers, Varuni Kondagunta, Robert Motzer

“…The objective of this study was to determine our institutional experience with cytoreductive nephrectomy alone or in conjunction with nephrectomy complete metastasectomy. …”
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Epigenetic «probes» for lung cancer monitoring: LINE-1 methylation pattern in blood- circulating DNA by A. A. Ponomaryova, Е. Y. Rykova, N. V. Cherdyntseva, A. A. Bondar, A. Y. Dobrodeev, A. A. Zavyalov, S. A. Tuzikov, L. O. Bryzgalov, T. I. Merkulova, V. V. Vlassov, P. P. Laktionov

“…That is why, along with the expected decrease in LINE-1met concentration in csb-cirDNA, we recorded an unexpected statistically significant increase of the LINE-1 methylation index determined as (LINE-1met/LINE-1Ind) due to the profound LINE-1Ind decrease. …”
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Clinical significance of HER2 in urothelial carcinoma and analysis of its correlation with glycolytic metabolic characteristics by Andong Guo, Andong Guo, Chenrui Wu, Jishuang Cao, Kejia Zhu, Kejia Zhu, Sentai Ding, Sentai Ding

“…We investigated the relationships between HER2 expression and metabolic indicators such as the Homeostatic Model Assessment for insulin resistance (HOMA-IR), beta-cell function (HOMA-β), the triglyceride-glucose (TyG) index, and lactate dehydrogenase (LDH) levels. HER2 status was determined using a standardized scoring system from the 2021 Clinical Pathological Expert Consensus on HER2 Testing in UC, China. …”
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Metabolome and transcriptome analysis reveal the pigments biosynthesis pathways in different color fruit peels of Clausena lansium L. Skeels by Zhichang Zhao, Mark Owusu Adjei, Ruixiong Luo, Huaping Yu, Yali Pang, Jian Wang, Yu Zhang, Jun Ma, Aiping Gao

“…Despite the significant increase of FLS expression in PP, the contents of kaempferol, quercetin, and myricetin significantly decreased, suggesting that the increase of FLS expression did not lead to an increase in flavonol biosynthesis.DiscussionThe competition between F3’H and F3’5’H may determine the ratio of Dp/Cy, the higher levels of F3’H, F3’5’H, and UFGT expression, lead to the increase accumulation of total anthocyanin and Dp/Cy in PP. …”
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Identification of promising SARS-CoV-2 main protease inhibitor through molecular docking, dynamics simulation, and ADMET analysis by Ganesh Sharma, Neeraj Kumar, Chandra Shekhar Sharma, Taha Alqahtani, Yewulsew Kebede Tiruneh, Sharifa Sultana, Gabriel Vinícius Rolim Silva, Gabriela de Lima Menezes, Magdi E. A. Zaki, Jonas Ivan Nobre Oliveira

“…The physicochemical properties, pharmacokinetics, and ADMET (Absorption, Distribution, Metabolism, Excretion, and Toxicity) profiles were evaluated to determine drug similarity and safety. Compound 4896 − 4038 proved to be the most promising candidate. …”
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The prevalence of malaria in the five districts of Limpopo Province, South Africa, 2015 - 2017 by M T Lamola, A Musekiwa, A de Voux, C Reddy, M Morifi, P C Mutevedzi

“…To measure the prevalence of malaria in Limpopo Province, the proportion of malaria cases that are imported and to determine factors associated with malaria from January 2015 to December 2017. …”
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“Holding on to Hope”: follow up qualitative findings of a tobacco treatment intervention for people experiencing mental health conditions by Tessa-May Zirnsak, Kristen McCarter, Melissa L. McKinlay, Ashleigh Guillaumier, Nadine Cocks, Catherine Brasier, Laura Hayes, Amanda L. Baker, Donita E. Baird, Billie Bonevski, Ron Borland, Ron Borland, David Castle, Erin Forbes, Peter J. Kelly, Catherine Segan, Catherine Segan, Rohan Sweeney, Alyna Turner, Alyna Turner, Jill M. Williams, Lisa Brophy, Lisa Brophy

“…Interviews were transcribed and analyzed with a thematic analysis methodology using NVivo 12. Key themes were determined using inductive coding.ResultsSix key themes were identified. …”
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Study protocol for the COPE study: COVID-19 in Older PEople: the influence of frailty and multimorbidity on survival. A multicentre, European observational study by Thomas Lee, Sandeep Singh, Phyo Kyaw Myint, Sheila Jones, Ben Carter, Susan Moug, Terry Quinn, Michael Thomas, Emma Bhatti, Angeline Price, Fenella Barlow-Pay, Siobhan Duffy, Lyndsay Pearce, Arturo Vilches-Moraga, Michael Stechman, Philip Braude, Emma Mitchell, Alessia Verduri, Kathryn McCarthy, Jonathan Hewitt, Charlotte Davey, Kiah Lunstone, Alice Cavenagh, Charlotte Silver, Thomas Telford, Rebecca Simmons, Dolcie Paxton, Francis Rickard, Mark Holloway, James Hesford, Tarik Jichi, Norman Galbraith, Jenny Edwards, Carly Bisset, Ross Alexander, Abigail Ingham, Roxanna Short, Aine McGovern, Jemima Collins, Eilidh Bruce, Alice Einarsson, Enrico Clini, Giovanni Guaraldi, Madeline Garcia, Shefali Sangani, Thomas Kneen, George Kyriakopoulos, Denise Tan

“…We will carry out a secondary analysis of the primary outcome by including additional clinical mediators which are determined statistically important using a likelihood ratio test. …”
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Patient participation in free cataract surgery: a cross-sectional study of the low-income elderly in urban China by Bo Qu, Hui Chen, Xuhua Tan, Xiaohang Wu, Haotian Lin, Zhenzhen Liu, Lixia Luo, Bo Zhang, Erping Long, Duoru Lin, Weirong Chen, Yizhi Liu, Haofeng Jiang, Jingjing Chen, Zhuoling Lin, Xiaoyan Li, Jinzhu Tang, Yingfen Lin

“…Objectives To explore the characteristics of the low-income elderly who underwent free cataract surgery and to determine the degree of patient satisfaction with the free cataract surgery programme in urban China.Methods A free cataract surgery management workflow was designed as a poverty relief project in Guangzhou. …”
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Promotion of microfracture-mediated cartilage repair by the intra-articular injection of Mg2+ by Zhian Chen, Tianhua Zhou, Zhengbo Yin, Peiya Duan, Ying Zhang, Yujiao Feng, Rongmao Shi, Yongqing Xu, Rongqing Pang, Hongbo Tan

“…The RT-qPCR results showed that sirtuin 1/bone morphogenetic protein-2/sex-determining region Y box 9 (SIRT1/BMP-2/SOX-9) and hypoxia-inducible factor 1-alpha (HIF-1α) messenger RNA levels were up-regulated after Mg2+ injection. …”
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Health-Related Quality of Life and Its Influencing Factors in Patients with Hepatitis B: A Cross-Sectional Assessment in Southeastern China by Ping Chen, Fen Zhang, Yiqun Shen, Yubo Cai, Chaolei Jin, Yan Li, Mingmin Tu, Weizhen Zhang, Yu Wang, Shi-Feng Zhang, Jiangyun Wang, Lanjuan Li

“…Disease stage and income emerged as key determinants of HRQoL scores. Augmenting social and medical supports for patients with HB, especially those with a socioeconomic status and an advanced disease stage, may help to enhance HRQoL.…”
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Correlation between Therapeutic Efficacy of CD34+ Cell Treatment and Directed In Vivo Angiogenesis in Patients with End-Stage Diffuse Coronary Artery Disease by Tien-Hung Huang, Cheuk-Kwan Sun, Yi-Ling Chen, Pei-Hsun Sung, Chi-Hsiang Chu, Mel S. Lee, Yuan-Ping Lin, Hon-Kan Yip, Fan-Yen Lee

“…The percentages of circulating EPCs with KDR+/CD34+/CD45−, CD133+/CD34+/CD45−, and CD34+ were determined in each patient using flow cytometry. PBMC-derived EPCs from all patients were subjected to DIVAA through a 14-day implantation in nude mice. …”
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Cross-sectional design and protocol for Artificial Intelligence Ready and Equitable Atlas for Diabetes Insights (AI-READI) by Gerald McGwin, Linda M Zangwill, Nicholas Evans, Shannon McWeeney, Cecilia S Lee, Bhavesh Patel, Jeffrey C Edberg, Cynthia Owsley, Aaron Lee, Cecilia Lee, Sally L Baxter, Michael Snyder, Samantha Hurst, Nicole Ehrhardt, Christopher Chute, Dawn S Matthies, Julia P Owen, Amir Bahmani, Sally Baxter, Edward Boyko, Aaron Cohen, Jorge Contreras, Garrison Cottrell, Virginia de Sa, Jeffrey Edberg, Irl Hirsch, Michelle Hribar, T.Y. Alvin Liu, Bonnie Maldenado, Sara Singer, Bradley Voytek, Joseph Yracheta, Linda Zangwill

“…Data are collected in a multivariable protocol containing over 10 domains, including vitals, retinal imaging, electrocardiogram, cognitive function, continuous glucose monitoring, physical activity, home air quality, blood and urine collection for laboratory testing and psychosocial variables including social determinants of health. There are three study sites: Birmingham, Alabama; San Diego, California; and Seattle, Washington.Ethics and dissemination AI-READI aims to establish standards, best practices and guidelines for collection, preparation and sharing of the data for the purposes of AI/ML, including guidance from bioethicists. …”
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